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  • 14 Dec 2011
  • Research & Ideas

The New Measures for Improving Nonprofit Performance

using systems thinking and complexity theory to help us understand the challenges at the ecosystem level. There's also growing attention to using randomized control trials in the social sector, which we tend to associate with drug trials.... View Details
Keywords: by Julia Hanna
  • 19 Nov 2014
  • HBS Case

Marketing Marijuana

something that hadn't been done in 81 years—make an illegal drug legal. “They do not need to buy it at a fancy store—they'll go to a back alley basement shop as long as the product delivers” Of course, the question remains: How will state... View Details
Keywords: by Michael Blanding; Food & Beverage
  • 05 Jul 2004
  • Research & Ideas

Radical Change, Entrepreneurial Opportunity

tightly coupled relationships with customers to engage in trials of different product concepts, producers and users can jointly learn about and make sense of the new technology. For instance, Surface Logix, a firm with highly sophisticated, flexible technology called... View Details
Keywords: by Michael J. Roberts; Technology
  • 29 May 2001
  • Research & Ideas

How Technological Disruption Changes Everything

and, finally, self-care. Microsoft has way overshot what the customer needs. —Clayton Christensen Christensen said that disruptive technologies in health care are coming in the form of better and more targeted drugs and rapidly improving... View Details
Keywords: by Sean Silverthorne; Health
  • 15 Jun 2016
  • Research & Ideas

These VC Partners May Make Your Firm Less Innovative

developed by the Food and Drug Administration (FDA), they were able to tell which companies were competitors in the same patient application areas (such as cardiology, oncology, or urology) and product classes. Then, using commercial... View Details
Keywords: by Michael Blanding; Financial Services; Banking
  • 25 Aug 2015
  • First Look

First Look Tuesday

to examine the phenomena in the context of health. In particular, we examine how an individual's prior experiences and the experiences of those around them alter the operational decisions that the individual makes. We draw on an exogenous announcement of negative news... View Details
  • 05 Nov 2007
  • Research & Ideas

The Changing Face of American Innovation

on? Are they concentrated in a specific industry or business type? A: Inventors can file for patents in many technology fields, ranging from chemicals and drugs to computer software to agricultural machinery. Immigrant contributions are... View Details
Keywords: by Sarah Jane Gilbert; Technology
  • 18 Apr 2019
  • Research & Ideas

Open Innovation Contestants Build AI-Based Cancer Tool

for Google, etc. AI is already being used as an adjunct to diagnosis in some settings. However, the bar for US Food & Drug Administration approval for a diagnostic test is appropriately high, and “products” will need to meet this bar... View Details
Keywords: by Martha Lagace; Health; Medical Devices & Supplies
  • 25 Oct 2016
  • First Look

October 25, 2016

insulate consumers from cost sharing, thereby undermining insurers’ ability to influence drug utilization. We study the impact of copay coupons on branded drugs first facing generic entry between 2007 and... View Details
Keywords: Sean Silverthorne
  • 07 Aug 2007
  • First Look

First Look: August 7, 2007

and issues around current practices. Purchase this note: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=807124 U.S. Food and Drug Administration Harvard Business School Note 807-050 Describes the U.S. FDA with particular... View Details
Keywords: Martha Lagace
  • 14 Dec 2010
  • First Look

First Look: Dec. 14

511-075 By 2009, Hikma Pharmaceuticals operated 13 manufacturing plants in 8 countries of which 5 were approved by the U.S. Food and Drug Administration. Hikma tracked its sales revenues over the period to show from where the largest... View Details
Keywords: Sean Silverthorne
  • 26 Apr 2004
  • Research & Ideas

A Clear Eye for Innovation

series of contact-lens products, introduced a drug for treating age-related macular degeneration, pioneered a new lens-manufacturing process that dramatically reduced production costs, and overtook J&J in some market segments. The... View Details
Keywords: by Charles A. O'Reilly III & Michael L. Tushman
  • 15 Feb 2000
  • Lessons from the Classroom

Delivering Information Services: A 30-Year Perspective

IPO in 1990 to a $10-billion company today, with a market value of close to $140 billion! I'm also doing research for a case on Drugstore.com, which is essentially a drug store "built" on the Internet. It's getting ready to... View Details
Keywords: by Staff
  • 07 Aug 2006
  • Research & Ideas

Whatever Happened to Caveat Emptor?

basic material needs to concerns about the safety and quality of these products. When products did fail—as happened dramatically in the late 1950s with the antinausea drug Thalidomide—such cases became the focus of aggressive consumer... View Details
Keywords: by Sean Silverthorne; Retail
  • 06 Jun 2017
  • First Look

First Look at New Research and Ideas: June 6, 2017

with revenue expectations of $1 billion in 2015. At the time of the acquisition, AbbVie received more than 60% of its sales from the drug Humira, a biologic agent used to treat several autoimmune diseases and malignancies. However, Humira... View Details
Keywords: Sean Silverthorne
  • 27 Feb 2018
  • First Look

First Look at New Research and Ideas, February 27, 2018

company. Purchase this case: https://cb.hbsp.harvard.edu/cbmp/product/718403-PDF-ENG Harvard Business School Case 618-033 BeiGene BeiGene was a biopharmaceutical company founded on exploiting a temporal regulatory policy discontinuity. Because of regulatory challenges... View Details
Keywords: Sean Silverthorne
  • 21 Jul 2015
  • First Look

First Look: July 21, 2015

new drug markets. Download working paper: https://www.hbs.edu/faculty/Pages/item.aspx?num=49384   Cases & Course Materials Harvard Business School Case 715-438 The Transformation of NCR During his tenure as CEO since 2005, Bill Nuti... View Details
Keywords: Sean Silverthorne
  • 27 Jan 2003
  • Research & Ideas

New Cluster Mapping Project Helps Companies Locate Facilities

A: There is some heartening progress. The word is out among retailers about the under-served market in inner cities. Drug chains, such as Walgreen's, and many other retailers, such as Home Depot, are pursuing this opportunity to good... View Details
Keywords: by Sean Silverthorne
  • 30 Oct 2007
  • First Look

First Look: October 30, 2007

Changing Context of Pharmaceutical Risk Mitigation Author:Arthur A. Daemmrich Periodical:Pharmacy in History 49, no. 2 (2007): 61-75 Abstract In the wake of Vioxx, Avandia, and other recent prominent cases of drugs found to cause side... View Details
Keywords: Sean Silverthorne
  • 22 Aug 2006
  • First Look

First Look: August 22, 2006

805-067 Molecular Insight has developed a novel biopharmaceutical to detect heart attacks. The company's unique approach to intellectual property protection uses the Hatch Waxman Act and the Orphan Drug Act. The company is struggling to... View Details
Keywords: Martha Lagace
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