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Why Partner with HBS Executive Education

Our leadership development ignites transformation. We believe that effective leadership development is critical for successfully driving transformative change. Our learning programs are designed to help you... View Details

22 Aug 2006
First Look

First Look: August 22, 2006

805-067 Molecular Insight has developed a novel biopharmaceutical to detect heart attacks. The company's unique approach to intellectual property protection uses the Hatch Waxman Act and the Orphan Drug Act. The company is struggling to... View Details

Keywords: Martha Lagace

27 Aug 2008
Research & Ideas

Creating Leaders for Science-Based Businesses

Science Complex—four multistory buildings, due for completion in 2011—the centerpiece of the initial phase of Harvard's 300-acre development on the Boston side of the Charles River. New Management Skills Needed Both in the scale and scope... View Details

Keywords: by Garry Emmons; Biotechnology; Health

01 Dec 2023
News

Educating Leaders for Today and Tomorrow

Illustration by Stephanie Dalton Cowan HBS is constantly taking steps, both small and large, to refine and improve the way it prepares its students and program participants to lead—both in today’s world and in a future we can’t yet imagine. By being creative, nimble,... View Details

12 Feb 2009
Working Paper Summaries

Platform Competition, Compatibility, and Social Efficiency

Keywords: by Ramon Casadesus-Masanell & Francisco Ruiz-Aliseda; Computer

June 2011 (Revised June 2013)
Case

Sino-Ocean Land: Responding to Change

By: Nicolas P. Retsinas, Jeffrey Hu and Runjiao Xu

In 2010, Sino-Ocean Land Holdings Limited was a highly successful, large real estate developer based in Beijing, China. Sino-Ocean Land had three main business segments—property development, property investment/management, and other real estate related businesses. From... View Details

Keywords: Organizational Change and Adaptation; Strategic Planning; Diversification; Property; Policy; State Ownership; Business Strategy; Business and Government Relations; Real Estate Industry; Beijing

2010
Article

Zwischen Familienerbe und globalem Markt. Eigentum und Management von großen westdeutschen Familienunternehmen im Wandel (1960-2008)

"Between Family Heritage and Global Market. Changes in Ownership and Management of Large West-German Family Firms (1960-2008)" Large family firms fall between two theoretical accounts. They neither follow the development path described by Alfred D. Chandler nor do they... View Details

Keywords: Business or Company Management; Family Ownership; Germany

Approximately 80% of the 9,000 wineries in the US breakeven or lose money. An even greater percentage, perhaps 90-95%, lose money on an economic basis (i.e., after a charge for the capital employed). Tegan Passalacqua is a Californian winemaker who appears to have... View Details

Meeting the Challenge of Corporate Entrepreneurship

To be competitive, companies must grow innovative new businesses. Corporate entrepreneurship, however, isn't easy. New ventures face innumerable barriers and seldom mesh smoothly with well-established systems, processes, and cultures. Nonetheless, success requires a... View Details

18 Dec 2018
First Look

New Research and Ideas, December 18, 2018

the threshold for research and development (R&D) investment in an economically viable product. Further, the small size of patient populations for orphan drugs, together with the increasing prevalence of biologics among orphan drugs,... View Details

Keywords: Dina Gerdeman

13 Jul 2020
Research & Ideas

Merck CEO Ken Frazier Discusses a COVID Cure, Racism, and Why Leaders Need to Walk the Talk

As chairman and CEO of the leading vaccine producer in the world, pharmaceutical giant Merck & Co., Ken Frazier has one of the highest-profile positions in global business. But Frazier, who is leading one of the firms on a charge to View Details

Keywords: by Staff; Pharmaceutical

April 30, 2020
Article

Leading Your Team Past the Peak of a Crisis

By: Rosabeth M. Kanter

In the middle of a crisis, everything looks like a failure. But it’s possible to come out the other end with a strong company—and often with a plan for growth. Companies with a people-first culture can succeed by paying attention to three things: establishing clear... View Details

Keywords: Crisis Management; Organizational Culture; Corporate Accountability; Collaborative Innovation and Invention

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2024
Working Paper

Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances

By: Srikant M. Datar, Amar Bhidé and Katherine Stebbins

This case history describes how Magnetic Resource Imaging (MRI) came to complement – and partially replace -- computed tomography (CT) imaging of soft tissue. Specifically, we chronicle 1) the development of foundational techniques and prototypes (through the 1970s);... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

SSRN

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2024
Working Paper

Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes how a chance discovery of bacteria that infect stomach linings completely changed how physicians treat ulcers. Specifically, we chronicle how: 1) two Australian physicians brought the bacterial infection to the world’s attention and... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

SSRN

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November 2017
Case

BeiGene

By: Willy Shih and Jimmy Zhang

BeiGene was a biopharmaceutical company founded on exploiting a temporal regulatory policy discontinuity. Because of regulatory challenges in China, most innovative new drugs launched there four to six years after their initial U.S. launches. This gave BeiGene a window... View Details

Keywords: Biotechnology; Pharmaceutical Company; Pharmaceuticals; China; Regulatory Environment; Business Strategy; Business Startups; Innovation Strategy; Situation or Environment; Pharmaceutical Industry; China

July–August 2011
Article

Putting Business Models Under the Microscope

By: K. Merchant, Tatiana Sandino and D. Huelsbeck

The article provides advice for financial managers on evaluating business models for corporate performance measurement. Emphasis is given to a study sponsored by the Chartered Institute of Management Accountants (CIMA) that examined the business model of a medical... View Details

Keywords: Business Model; Financial Management; Performance Evaluation

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March 2005
Background Note

Home Video Games: Generation Seven

By: Elie Ofek

Discusses the issues facing firms in the seventh generation of home video game platforms. In particular, Sony and Microsoft plan to launch new game consoles in the 2005 to 2006 time frame. Each firm seems to be following a different strategy. Microsoft wants to launch... View Details

Keywords: Marketing Strategy; Competitive Strategy; Technological Innovation; Information Infrastructure; Applications and Software; Entertainment and Recreation Industry; Information Technology Industry

October 2003 (Revised January 2009)
Case

Transforming Matsui Securities

By: Lynda M. Applegate, Masako Egawa, Jamie Ladge and Haruki Umezawa

Michio Matsui, president and CEO of Matsui Securities, transformed a small regional securities company into a leading player in the online broking industry in Japan. Discusses how he transformed the business model and culture of the company and took advantage of the... View Details

Keywords: Transformation; Innovation and Invention; Leading Change; Organizational Change and Adaptation; Business Model; Organizational Culture; Financial Markets; Competitive Advantage; Japan

April 2001
Exercise

Selecting a Hosting Provider

Asks students to develop criteria for selecting a Web hosting company, then to select one of three profiled in case exhibits. In choosing a hosting vendor, students represent one of two companies: one a start-up, the other an industrial-age manufacturer. By assigning... View Details

Keywords: Job Cuts and Outsourcing; Partners and Partnerships; Internet