Publications

16 Jan 2018
First Look

First Look at New Research and Ideas, January 16, 2018

on average, more valuable—they are more clinically effective; have higher patent citations; lead to more revenue and to higher stock market value. Using variation in the expansion of Medicare prescription drug coverage, we show that firms... View Details

Keywords: Sean Silverthorne

November 1995 (Revised February 1996)
Case

Monsanto Company: The Coming of Age of Bio-Technology

By: Ray A. Goldberg and Thomas N. Urban Jr

Monsanto has one product, Roundup, accounting for 30% of company net income and is going off patent. How should the company position itself and its products in the future? View Details

Keywords: Patents; Product Positioning; Strategic Planning; System Shocks; Biotechnology Industry

November 1978 (Revised October 1989)
Case

Amicon Corp. (B)

Details the negotiation between Amicon and three potential licensees, Jackson, Maynard-Smith and Behrstein. View Details

Keywords: Technology; Patents; Negotiation Process; Negotiation Participants; Health Care and Treatment; Biotechnology Industry

08 Nov 2016
First Look

November 8, 2016

work in linked fields. Our analysis uses 1.8 million U.S. patents and their citation properties to map the innovation network and its strength. Past innovation network structures are calculated using citation patterns across technology... View Details

Keywords: Sean Silverthorne

27 Aug 2008
Research & Ideas

Creating Leaders for Science-Based Businesses

sector. Pisano proposes more vertical integration, fewer but closer long-term collaborations, and quasi-public corporations. In academia he calls for more cross-disciplinary research and for universities to strive to disseminate new knowledge and liberate it from... View Details

Keywords: by Garry Emmons; Biotechnology; Health

January 2021 (Revised June 2021)
Case

Hester Pharmaceuticals (A): A Pricing Dilemma

By: Dante Roscini and John Masko

In August 2019, the leadership of Hester Pharmaceuticals (Hester) had a problem. Italy promised to be a key market for their new breakthrough oncology drug Akrozumab, but for almost two years, its single-payer healthcare system had been unable to agree with Hester on a... View Details

Keywords: Macroeconomics; Trade; Price; Global Range; Global Strategy; Globalized Markets and Industries; Health Care and Treatment; Patents; Monopoly; Negotiation; Business and Government Relations; Risk and Uncertainty; Human Needs; Business Strategy; Commercialization; Pharmaceutical Industry; Italy

16 Jul 2024
Research & Ideas

Weighing Digital Tradeoffs in Private Equity

and sales by 7 percent. Moreover, the team found that improving digital technology increased innovation; companies that received more technology investment held more new patents afterward. “If there are firms that haven’t been interested... View Details

Keywords: by Michael Blanding; Financial Services

June 2019
Teaching Note

Zebra Medical Vision

By: Shane Greenstein and Sarah Gulick

Teaching note is meant to accompany Zebra Medical Vision case, which offers a look at a company’s decisions as a small startup competing with other startups and major technology companies. It also demonstrates the challenges faced by a machine learning company working... View Details

Keywords: Business Startups; Science-Based Business; Applications and Software; Patents; Cross-Cultural and Cross-Border Issues; Health Care and Treatment; Health Industry; Medical Devices and Supplies Industry; Technology Industry; Israel

September 2007 (Revised May 2011)
Case

Commercializing an MRI Breakthrough

The challenges and best strategies for the commercialization of university technologies are illustrated in this case which documents an MRI breakthrough that arose from the Charles Marcus laboratory at Harvard. Students discuss the interdependencies of intellectual... View Details

Keywords: Business Model; Decision Choices and Conditions; Higher Education; Patents; Research and Development; Science-Based Business; Commercialization

September 2010
Teaching Note

Alnylam Pharmaceuticals: Building Value from the IP Estate (TN)

By: Willy C. Shih

Teaching Note for 611009. View Details

Keywords: Value; Patents; Corporate Strategy; Competition; Research and Development; Lawsuits and Litigation; Pharmaceutical Industry; United States

March 2017 (Revised February 2025)
Case

Edwin Land: The Art and Science of Innovation

By: Tom Nicholas, Christopher T. Stanton and Matthew G. Preble

Throughout the second half of the 20th century, Polaroid first invented—and then continuously reinvented—the field of instant photography. Under the leadership of its mercurial founder Edwin Land, the company regularly released new instant cameras and films, often... View Details

Keywords: Instant Photography; Company History; Change Management; Disruption; Forecasting and Prediction; Entrepreneurship; Business History; Innovation Strategy; Disruptive Innovation; Innovation and Management; Intellectual Property; Patents; Product Marketing; Brands and Branding; Product Launch; Product Development; Chemical Industry; Consumer Products Industry; United States