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  • All HBS Web  (1,036)
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    • News  (155)
    • Research  (661)
    • Events  (13)
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  • June 2021
  • Article

From Predictions to Prescriptions: A Data-driven Response to COVID-19

By: Dimitris Bertsimas, Léonard Boussioux, Ryan Cory-Wright, Arthur Delarue, Vassilis Digalakis Jr, Alexander Jacquillat, Driss Lahlou Kitane, Galit Lukin, Michael Lingzhi Li, Luca Mingardi, Omid Nohadani, Agni Orfanoudaki, Theodore Papalexopoulos, Ivan Paskov, Jean Pauphilet, Omar Skali Lami, Bartolomeo Stellato, Hamza Tazi Bouardi, Kimberly Villalobos Carballo, Holly Wiberg and Cynthia Zeng
The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing measures to slow the disease, at... View Details
Keywords: COVID-19; Health Pandemics; AI and Machine Learning; Forecasting and Prediction; Analytics and Data Science
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Bertsimas, Dimitris, Léonard Boussioux, Ryan Cory-Wright, Arthur Delarue, Vassilis Digalakis Jr, Alexander Jacquillat, Driss Lahlou Kitane, Galit Lukin, Michael Lingzhi Li, Luca Mingardi, Omid Nohadani, Agni Orfanoudaki, Theodore Papalexopoulos, Ivan Paskov, Jean Pauphilet, Omar Skali Lami, Bartolomeo Stellato, Hamza Tazi Bouardi, Kimberly Villalobos Carballo, Holly Wiberg, and Cynthia Zeng. "From Predictions to Prescriptions: A Data-driven Response to COVID-19." Health Care Management Science 24, no. 2 (June 2021): 253–272.
  • January 2025
  • Case

Moderna: Democratizing Artificial Intelligence

By: Iavor I. Bojinov, Karim R. Lakhani, Annika Hildebrandt and James Weber
The case study examines Moderna's journey in democratizing artificial intelligence (AI), particularly generative AI, across its workforce. It details the company's "digital-first, AI-focused" approach, including the rollout of OpenAI's ChatGPT Enterprise to all... View Details
Keywords: AI and Machine Learning; Technology Adoption; Innovation Strategy; Governance Controls; Biotechnology Industry
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Bojinov, Iavor I., Karim R. Lakhani, Annika Hildebrandt, and James Weber. "Moderna: Democratizing Artificial Intelligence." Harvard Business School Case 625-070, January 2025.
  • May–June 2024
  • Article

Should Your Brand Hire a Virtual Influencer?

By: Serim Hwang, Shunyuan Zhang, Xiao Liu and Kannan Srinivasan
Followers respond more favorably to sponsored posts by virtual influencers versus those by humans, costs are lower, and creating an influencer from scratch allows marketers to introduce more diversity. View Details
Keywords: Social Media; AI and Machine Learning; Brands and Branding; Power and Influence
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Hwang, Serim, Shunyuan Zhang, Xiao Liu, and Kannan Srinivasan. "Should Your Brand Hire a Virtual Influencer?" Harvard Business Review 102, no. 3 (May–June 2024): 56–60.
  • Article

Using Gen AI for Early-Stage Market Research

By: James Brand, Ayelet Israeli and Donald Ngwe
Generative AI, particularly large language models (LLMs), offers a promising new tool for early-stage market research by simulating customer responses to product concepts. This can allow companies to draw conclusions similar to those they’d obtain by surveying... View Details
Keywords: Large Language Models; Large Language Model; Generative Ai; Artificial Intelligence; Market Research; Research; Marketing; AI and Machine Learning; Analytics and Data Science; Analysis; Customers; Consumer Behavior; Technology Industry; Information Technology Industry
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Brand, James, Ayelet Israeli, and Donald Ngwe. "Using Gen AI for Early-Stage Market Research." Harvard Business Review (website) (July 18, 2025).
  • January 2025
  • Teaching Note

AGENTS.inc: Pathways to Growth at an AI Startup

By: Frank Nagle and Susan Pinckney
Teaching Note for HBS Case No. 724-444. In 2024, AI agent startup company AGENTS.inc faced multiple strategic decisions that could shape the company’s ability to grow into the future AI agent market leader. View Details
Keywords: Business Startups; AI and Machine Learning; Growth and Development Strategy; Open Source Distribution; Entrepreneurial Finance; Competition; Computer Industry; Technology Industry; Europe; Germany
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Nagle, Frank, and Susan Pinckney. "AGENTS.inc: Pathways to Growth at an AI Startup." Harvard Business School Teaching Note 725-353, January 2025.
  • October 2023
  • Case

Fixie and Conversational AI Sidekicks

By: Jeffrey J. Bussgang and Carin-Isabel Knoop
In March 2023, Fixie Co-Founder and Chief Architect Matt Welsh and co-founders had the kind of meeting no founders want to have. The president of leading artificial intelligence (AI) research and deployment firm OpenAI, which had catapulted into fame with its ChatGPT... View Details
Keywords: Large Language Model; Entrepreneurship; Decision Choices and Conditions; AI and Machine Learning; Technological Innovation; Competitive Strategy; Technology Industry; United States
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Bussgang, Jeffrey J., and Carin-Isabel Knoop. "Fixie and Conversational AI Sidekicks." Harvard Business School Case 824-037, October 2023.
  • 2024
  • Working Paper

Old Moats for New Models: Openness, Control, and Competition in Generative AI

By: Pierre Azoulay, Joshua L. Krieger and Abhishek Nagaraj
Drawing insights from the field of innovation economics, we discuss the likely competitive environment shaping generative AI advances. Central to our analysis are the concepts of appropriability—whether firms in the industry are able to control the knowledge generated... View Details
Keywords: Technological Innovation; AI and Machine Learning; Open Source Distribution; Policy
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Azoulay, Pierre, Joshua L. Krieger, and Abhishek Nagaraj. "Old Moats for New Models: Openness, Control, and Competition in Generative AI." NBER Working Paper Series, No. 7442, May 2024.
  • July 2024
  • Article

Chatbots and Mental Health: Insights into the Safety of Generative AI

By: Julian De Freitas, Ahmet Kaan Uğuralp, Zeliha Uğuralp and Stefano Puntoni
Chatbots are now able to engage in sophisticated conversations with consumers. Due to the ‘black box’ nature of the algorithms, it is impossible to predict in advance how these conversations will unfold. Behavioral research provides little insight into potential safety... View Details
Keywords: Autonomy; Chatbots; New Technology; Brand Crises; Mental Health; Large Language Model; AI and Machine Learning; Behavior; Well-being; Technological Innovation; Ethics
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De Freitas, Julian, Ahmet Kaan Uğuralp, Zeliha Uğuralp, and Stefano Puntoni. "Chatbots and Mental Health: Insights into the Safety of Generative AI." Journal of Consumer Psychology 34, no. 3 (July 2024): 481–491.
  • September 2023
  • Case

Ada: Cultivating Investors

By: Reza Satchu and Patrick Sanguineti
Mike Murchison, co-founder and CEO of Ada, has an enviable dilemma. Launched in 2016 by Murchison and his co-founder David Hariri, Ada is an AI-native company that aims to revolutionize how businesses approach customer service. The company has already attracted a buzz,... View Details
Keywords: Founder; Fundraising; Business Startups; Decisions; Entrepreneurship; Venture Capital; AI and Machine Learning; Technology Industry
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Satchu, Reza, and Patrick Sanguineti. "Ada: Cultivating Investors." Harvard Business School Case 824-090, September 2023.
  • 2025
  • Working Paper

Lessons from an App Update at Replika AI: Identity Discontinuity in Human-AI Relationships

By: Julian De Freitas, Noah Castelo, Ahmet Kaan Uğuralp and Zeliha Oğuz-Uğuralp
As consumers increasingly interact with AI applications specialized for social relationships, what is the nature and depth of these relationships among actual users, and can company actions influence these dynamics? We find that active users of the US-based AI... View Details
Keywords: AI and Machine Learning; Welfare; Loss; Well-being; Identity; Perception; Relationships
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De Freitas, Julian, Noah Castelo, Ahmet Kaan Uğuralp, and Zeliha Oğuz-Uğuralp. "Lessons from an App Update at Replika AI: Identity Discontinuity in Human-AI Relationships." Harvard Business School Working Paper, No. 25-018, October 2024. (Revised May 2025.)
  • September–October 2024
  • Article

The Crowdless Future? Generative AI and Creative Problem-Solving

By: Léonard Boussioux, Jacqueline N. Lane, Miaomiao Zhang, Vladimir Jacimovic and Karim R. Lakhani
The rapid advances in generative artificial intelligence (AI) open up attractive opportunities for creative problem-solving through human-guided AI partnerships. To explore this potential, we initiated a crowdsourcing challenge focused on sustainable, circular economy... View Details
Keywords: Large Language Models; Generative Ai; Crowdsourcing; AI and Machine Learning; Creativity; Technological Innovation
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Boussioux, Léonard, Jacqueline N. Lane, Miaomiao Zhang, Vladimir Jacimovic, and Karim R. Lakhani. "The Crowdless Future? Generative AI and Creative Problem-Solving." Organization Science 35, no. 5 (September–October 2024): 1589–1607.
  • 2024
  • Working Paper

Climate Solutions, Transition Risk, and Stock Returns

By: Shirley Lu, Edward J. Riedl, Simon Xu and George Serafeim
Using large language models to measure firms' climate solution products and services, we find that high-climate solution firms exhibit lower stock returns and higher market valuation multiples. Their stock prices respond positively to events signaling increased demand... View Details
Keywords: Technology; Generative Ai; Large Language Models; Climate Finance; Climate Change; Innovation and Invention; Environmental Sustainability; AI and Machine Learning; Investment; Financial Markets
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Lu, Shirley, Edward J. Riedl, Simon Xu, and George Serafeim. "Climate Solutions, Transition Risk, and Stock Returns." Harvard Business School Working Paper, No. 25-024, November 2024.
  • October 2023 (Revised January 2025)
  • Case

Sydney Loves Kevin

By: Ryan W. Buell and Himabindu Lakkaraju
Kevin Roose was a columnist and podcast host for the New York Times, who focused on technology and its effects on society. When Microsoft launched the latest version of its search engine Bing in February 2023, the company invited Roose to its Redmond campus to... View Details
Keywords: Newspapers; AI and Machine Learning; Technology Adoption; Technological Innovation; Perspective; Media and Broadcasting Industry; Technology Industry
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Buell, Ryan W., and Himabindu Lakkaraju. "Sydney Loves Kevin." Harvard Business School Case 624-039, October 2023. (Revised January 2025.)
  • March–April 2025
  • Article

Strategy in an Era of Abundant Expertise: How to Thrive When AI Makes Knowledge and Know-How Cheaper and Easier to Access

By: Bobby Yerramilli-Rao, John Corwin, Yang Li and Karim R. Lakhani
The AI era is in its early stages, and the technology is evolving extremely quickly. Providers are rapidly introducing AI "copilots," "bots," and "assistants" into applications to augment employees' workflows. Examples include GitHub Copilot for coding, ServiceNow... View Details
Keywords: AI; AI and Machine Learning; Performance Productivity; Experience and Expertise; Technology Adoption
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Yerramilli-Rao, Bobby, John Corwin, Yang Li, and Karim R. Lakhani. "Strategy in an Era of Abundant Expertise: How to Thrive When AI Makes Knowledge and Know-How Cheaper and Easier to Access." Harvard Business Review 103, no. 2 (March–April 2025): 72–81.
  • 2025
  • Working Paper

Global Evidence on Gender Gaps and Generative AI

By: Nicholas G. Otis, Solène Delecourt, Katelynn Cranney and Rembrand Koning
Generative AI has the potential to transform productivity and reduce inequality, but only if adopted broadly. In this paper, we show that recently identified gender gaps in generative AI use are nearly universal. Synthesizing data from 18 studies covering more than... View Details
Keywords: AI and Machine Learning; Gender; Equality and Inequality; Technology Adoption; Behavior
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Otis, Nicholas G., Solène Delecourt, Katelynn Cranney, and Rembrand Koning. "Global Evidence on Gender Gaps and Generative AI." Harvard Business School Working Paper, No. 25-023, October 2024. (Revised January 2025.)
  • September 2024 (Revised January 2025)
  • Exercise

Building an AI First Snack Company: A Hands-on Generative AI Exercise

By: Iavor I. Bojinov
Although the term 'Generative AI' (GenAI) is widely recognized, its practical application in daily workflows has yet to be understood. This exercise introduces students to GenAI tools, demonstrating how they can be seamlessly integrated into professional work practices... View Details
Keywords: AI and Machine Learning; Technology Adoption; Marketing Strategy; Product Launch; Brands and Branding
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Bojinov, Iavor I. "Building an AI First Snack Company: A Hands-on Generative AI Exercise." Harvard Business School Exercise 625-052, September 2024. (Revised January 2025.)
  • March 2023
  • Teaching Note

VideaHealth: Building the AI Factory

By: Karim R. Lakhani
Teaching Note for HBS Case No. 621-021. The case “VideaHealth: Building the AI Factory” examines the creation of dental startup VideaHealth (Videa) and the development of its artificial intelligence (AI)-led business strategy through the eyes of founder and CEO Florian... View Details
Keywords: AI and Machine Learning; Applications and Software; Business Model; Marketing Strategy; Product Development; Health Industry; Technology Industry
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Lakhani, Karim R. "VideaHealth: Building the AI Factory." Harvard Business School Teaching Note 623-073, March 2023.
  • July 2024
  • Article

How Artificial Intelligence Constrains Human Experience

By: A. Valenzuela, S. Puntoni, D. Hoffman, N. Castelo, J. De Freitas, B. Dietvorst, C. Hildebrand, Y.E. Huh, R. Meyer, M. Sweeney, S. Talaifar, G. Tomaino and K. Wertenbroch
Many consumption decisions and experiences are digitally mediated. As a consequence, consumer behavior is increasingly the joint product of human psychology and ubiquitous algorithms (Braun et al. 2024; cf. Melumad et al. 2020). The coming of age of Large Language... View Details
Keywords: Large Language Model; User Experience; AI and Machine Learning; Consumer Behavior; Technology Adoption; Risk and Uncertainty; Cost vs Benefits
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Valenzuela, A., S. Puntoni, D. Hoffman, N. Castelo, J. De Freitas, B. Dietvorst, C. Hildebrand, Y.E. Huh, R. Meyer, M. Sweeney, S. Talaifar, G. Tomaino, and K. Wertenbroch. "How Artificial Intelligence Constrains Human Experience." Journal of the Association for Consumer Research 9, no. 3 (July 2024): 241–256.
  • February 2022 (Revised November 2022)
  • Case

Nuritas

By: Mitchell Weiss, Satish Tadikonda, Vincent Dessain and Emer Moloney
Nora Khaldi had built a technology “to unlock the power of nature” in the service of extending human lifespan and improving health, and now in April 2020 was debating telling her Board of Directors she wanted to put on ice some of her discoveries. Nuritas, the company... View Details
Keywords: Cash Burn; Cash Flow Analysis; Pharmaceutical Companies; Founder; Artificial Intelligence; AI; Entrepreneurship; Health Testing and Trials; Health Care and Treatment; Decision Making; Market Entry and Exit; AI and Machine Learning; Pharmaceutical Industry
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Weiss, Mitchell, Satish Tadikonda, Vincent Dessain, and Emer Moloney. "Nuritas." Harvard Business School Case 822-080, February 2022. (Revised November 2022.)
  • March 27, 2025
  • Article

How One Company Used AI to Broaden Its Customer Base

By: Sunil Gupta and Frank V. Cespedes
The software company SAP successfully leveraged AI tools to begin selling to the small and medium enterprises (SMEs) market, which had previously been uneconomical for its in-person sales approach. By mapping the customer journey and deploying over 40 AI tools, SAP... View Details
Keywords: AI and Machine Learning; Sales; Business Strategy; Market Entry and Exit
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Gupta, Sunil, and Frank V. Cespedes. "How One Company Used AI to Broaden Its Customer Base." Harvard Business Review (website) (March 27, 2025).
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