Publications

November 2018
Case

David Hysong and SHEPHERD Therapeutics

By: Ananth Raman, John Masko and Aldo Sesia

In 2016, David Hysong, at age 27, found out he had a rare, incurable cancer. Rather than wait around to die, Hysong, a recent graduate of Harvard Divinity School, decided to launch a biotechnology company called Shepherd Therapeutics to development treatments for his... View Details

Keywords: Cancer; Therapeutics; Drugs; Health Care and Treatment; Business Startups; Product Development; Financing and Loans; Growth and Development Strategy; Problems and Challenges

01 Jul 2013
Research & Ideas

Crowdfunding a Poor Investment?

usually required in a venture capital presentation. “A lot of companies that probably shouldn't get funding will get it” As enticing as crowdfunding is as a concept, it may ultimately have little power to... View Details

Keywords: by Michael Blanding; Financial Services

02 Nov 2020
Blog Post

WE RISE

someone different.” “The venture industry is a really great job for women—and for men too—because it’s right on the cutting edge. You’re shaping the future.”—Sonja Hoel Perkins (MBA 1993), founder and managing director, Perkins View Details

Keywords: Venture Capital / Private Equity; Venture Capital / Private Equity; Venture Capital / Private Equity

November 2022 (Revised March 2024)
Case

Replika AI: Monetizing a Chatbot

By: Julian De Freitas and Nicole Tempest Keller

In early 2018, Eugenia Kuyda, co-founder and CEO of San Francisco-based chatbot Replika AI, was deciding how to monetize the app she had built. Launched in 2017, Replika was a consumer AI “companion app” developed by a team of AI software engineers originally based in... View Details

Keywords: Mental Health; Subscriber Models; TAM; Monetization Strategy; Marketing Strategy; Product Marketing; AI and Machine Learning; Applications and Software; Product Positioning; Health Disorders; Technology Industry

04 Feb 2014
Blog Post

VCPE Club prepares for their annual conference…20 years and running!

Women in Private Equity. All panels will be comprised of a blend of institutional investment managers, fund general partners, advisors, and intermediaries, each with extensive experience in the private equity and View Details

Research Summary

Formulating technology commercialization strategies

Even if young organizations succeed in acquiring the specialized talent necessary to further develop a recently-discovered technology, they may face an uncertain path in commercializing the original invention. Initial conceptions of what might constitute a useful... View Details

December 2009 (Revised March 2025)
Case

Phreesia: The Patient Intake Company

By: Regina E. Herzlinger, Sunaina Yarlagadda and Brian L. Walker

How should the co-founders of an organization that provides patient sign-in and billing services scale their company after five years of successfully targeting small private physician practices? Phreesia had deployed a direct mail and sales force strategy that resulted... View Details

Keywords: Advertising; Social Entrepreneurship; Revenue; Health Care and Treatment; Health Industry

Entrepreneurs who dream of building the next Amazon, Facebook or Google have the opportunity to take advantage of one of the most powerful economic engines the world has ever known: venture capital. To do so, you need to woo, impress, and persuade venture... View Details

April 2006 (Revised April 2012)
Background Note

The Role of Private Equity Firms in Merger and Acquisition Transactions

By: William E. Fruhan Jr.

Explores the importance of private equity firms in merger and acquisitions activity around the globe. In many countries, these firms now account for one quarter of the total merger and acquisition activity of all firms. The larger private equity firms generate fees for... View Details

Keywords: Leveraged Buyouts; Mergers and Acquisitions; Private Equity; Investment Funds; Value Creation

April 2019 (Revised June 2019)
Case

Western Governors University: 10x Vision

By: William R. Kerr and Susie L. Ma

Western Governors University (WGU) was a nonprofit institution of higher education whose online learning model served more than 100,000 students in 2019 and was scaling rapidly. President Scott Pulsipher wanted to expand WGU’s reach to millions more with a plan called... View Details

Keywords: Online Education; Enrollment; Scaling; Higher Education; Internet and the Web; Business Model; Expansion; Growth and Development Strategy; Education Industry; United States

December 2004 (Revised October 2005)
Case

Intel Research: Exploring the Future

By: Alan D. MacCormack and Kerry Herman

It is 2004 and David Tennenhouse, the director of Intel Research, is reviewing the organization he has built since 2000. Intel Research was charged with exploring new and disruptive technologies that lay off the "silicon roadmap" that drove most of Intel's R&D efforts.... View Details

Keywords: Disruptive Innovation; Technological Innovation; Research and Development; Performance Evaluation; Venture Capital; Technology Networks; Semiconductor Industry; United States

04 Dec 2012
First Look

First Look: December 4

Lerner, Morten Sorensen, and Per Strömberg Publication:Journal of Finance (forthcoming) Abstract A long-standing controversy is whether LBOs relieve managers from short-term pressures of dispersed shareholders, or whether LBO funds... View Details

Keywords: Carmen Nobel

November 2010 (Revised May 2014)
Case

Dow's Bid for Rohm and Haas

By: Benjamin C. Esty and David Lane

This case analyzes Dow Chemical Company's proposed acquisition of Rohm and Haas in 2008. The $18.8 billion acquisition was part of Dow's strategic transformation from a slow-growth, low-margin, and cyclical producer of basic chemicals into a higher-growth,... View Details

Keywords: Mergers and Acquisitions; Financial Crisis; Capital Structure; Financial Condition; Financial Management; Contracts; Lawsuits and Litigation; Risk and Uncertainty; Valuation; Chemical Industry

21 Feb 2005
Research & Ideas

The VC Quandary: Too Much Money

It might be hard for the ordinary business owner or consumer to imagine having "too much" money. But that's exactly where the venture capital industry finds itself: with too much money available for the number of emerging... View Details

Keywords: by Julie Jette; Financial Services

June 2005 (Revised May 2006)
Case

Vidient (A)

Vidient, a young company, is in the process of being spun out of a much larger, established Japanese business. Vidient is in the business of analyzing the feeds from security cameras and catches security breaches automatically, without human assistance. The parent... View Details

Keywords: Technological Innovation; Business Growth and Maturation; Corporate Entrepreneurship; Financing and Loans; Business Startups; Service Industry; Japan

Find at Harvard

October 2002 (Revised December 2003)
Case

Collabrys, Inc. (A)-The Evolution of a Startup

By: Dorothy A. Leonard and Brian DeLacey

The CEO of a two-year-old start-up must now decide whether to become a technology provider or a service agency. In a time of enormous uncertainty about the viability of various business models for Internet-delivered services and products, Collabrys has survived the... View Details

Keywords: Risk and Uncertainty; Internet and the Web; Corporate Entrepreneurship; Corporate Strategy; Technological Innovation; Cost vs Benefits; Partners and Partnerships; Business Growth and Maturation; Business Startups; Corporate Finance; United States