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  • 22 Nov 2004
  • Research & Ideas

Side Effects: The Case of Propecia

wives, believing such campaigns would not be cost effective. As Wosinska put the problem: "How does a pharma talk to barbers?" In the end, first-year sales beat internal estimates, thanks to pent-up demand. Propecia is now a... View Details
Keywords: by Sean Silverthorne; Health; Pharmaceutical
  • 15 Feb 2012
  • Working Paper Summaries

Learning from My Success and From Others’ Failure: Evidence from Minimally Invasive Cardiac Surgery

Keywords: by KC Diwas, Bradley R. Staats & Francesca Gino; Health
  • June 2024
  • Article

Valuing the Societal Impact of Medicines and Other Health Technologies: A User Guide to Current Best Practices

By: Jason Shafrin, Jaehong Kim, Joshua T. Cohen, Louis P. Garrison, Dana A. Goldman, Jalpa A. Doshi, Joshua Krieger, Darius N. Lakdawalla, Peter J. Neumann, Charles E. Phelps, Melanie D. Whittington and Richard Willke
This study argues that value assessment conducted from a societal perspective should rely on the Generalized Cost-Effectiveness Analysis (GCEA) framework proposed herein. Recently developed value assessment inventories—such as the Second Panel on Cost-Effectiveness’s... View Details
Keywords: Health Care and Treatment; Valuation; Cost vs Benefits; Society
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  • April 2024 (Revised November 2024)
  • Case

Moderna: Pioneering a People Platform to Accelerate Science Innovation

By: Tatiana Sandino, Emil Dy and Samuel Grad
Moderna was founded in 2010 to explore how messenger ribonucleic acid (mRNA) could be used to create breakthrough medicines by encoding instructions for the body to create antibodies. When Stéphane Bancel (HBS 2000) took over in 2011, he bet on the potential of this... View Details
Keywords: Disruptive Innovation; Talent and Talent Management; Selection and Staffing; AI and Machine Learning; Digital Strategy; Innovation and Management; Leadership Development; Management Practices and Processes; Management Systems; Organizational Culture; Performance Evaluation; Alignment; Employee Relationship Management; Science-Based Business; Expansion; Pharmaceutical Industry; Biotechnology Industry; United States
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  • December 2021
  • Article

The Evolutionary Nature of Breakthrough Innovation: An Empirical Investigation of Firm Search Strategies

By: Dominika Kinga Randle and Gary P. Pisano
Breakthrough innovation has been an important topic of study for generations of scholars. Previous research in this domain has focused on exploring the way breakthroughs emerge from cumulative combination and recombination of prior technologies and knowledge components... View Details
Keywords: Breakthrough Innovation; Exploration And Exploitation; Search Strategy; Innovation and Invention; Technological Innovation; Strategy
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  • 2020
  • Book

Capitalism at Risk: How Business Can Lead

By: Joseph L. Bower, Dutch Leonard and Lynn S. Paine
Who should take the lead in fixing market capitalism? Business—not government alone. The spread of capitalism worldwide has made people wealthier than ever before. But capitalism's future is far from assured. Pandemics, income inequality, resource depletion, mass... View Details
Keywords: Capitalism; Business And Society; Economic Systems; Economic Growth; Policy; Leading Change; Corporate Social Responsibility and Impact; Business and Community Relations; Corporate Strategy
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  • January 2008
  • Article

How to Change the World

By: Howard H. Stevenson
Alan Wilson has a decision to make. The CEO of his company, Grepter, wants him to relocate to Zurich, where he can gain valuable experience for a rise to the top. Karl, his best friend, hopes to lure him to a hedge fund that promises big money fast. Shiori, an enticing... View Details
Keywords: Decision Choices and Conditions; Values and Beliefs; Compensation and Benefits; Personal Development and Career; Power and Influence
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    Journal of Economics & Management Strategy (JEMS)

    Together with Prof. Daniel F. Spulber (Kellogg School of Management at Northwestern University), I edit the Journal of Economics & Management Strategy (JEMS), the leading academic journal on the economics of strategy. JEMS is based at Harvard Business... View Details
    • 11 Feb 2020
    • Sharpening Your Skills

    10 Rules Entrepreneurs Need to Know Before Adopting AI

    and understand the input needed and the internal workflow used by businesses in order to trust AI’s judgments and validate results. Organizational shift: Towards a more open and experimental culture. ML/AI engineers are still a novelty in... View Details
    Keywords: by Rocio Wu
    • 15 Jun 2007
    • Research & Ideas

    Remembering Alfred Chandler

    and view this page again, you will be able to play this video.   Jeffrey Fear Jeffrey Fear has been an associate professor at Harvard Business School since 2001 in the Business, Government, and International Economy unit. Chandler's... View Details
    Keywords: by Sean Silverthorne
    • Web

    Student Activities - Health Care

    and figures about where students are securing internships and full-time positions. Health Care Career Days Offers panels and presentations designed to introduce students to diverse health care industries, including life sciences, digital health, payors, providers,... View Details
    • 08 Jan 2019
    • First Look

    New Research and Ideas, January 8, 2019

    international audiences was indeed shifting in the intended direction. Several observers were further worried that the younger generation was finding Israel even less relevant and urged for devising a new approach. What should or could... View Details
    Keywords: Dina Gerdeman
    • 30 Aug 2004
    • Research & Ideas

    Real Estate: The Most Imperfect Asset

    trying to augment the curriculum with international cases. For example, I wrote a case about a hotel in Barcelona, a shopping center development in Hungary, and the recapitalization of Canary Wharf in London. Currently, most of my focus... View Details
    Keywords: by Sarah Jane Johnston; Construction; Real Estate
    • Research Summary

    Corporate Lobbying Strategy and Foreign MNEs

    “U.S. Defense Contracts and the Lobbying Strategies of Foreign MNEs: The Liability of Foreignness and Make-or-Buy Decisions about Political Goods”

    Many firms engage in lobbying with the expectation that their lobbying efforts will... View Details

    Keywords: Non-market Strategy; Political Strategy; Lobbying; Make V. Buy; Multinational Enterprise; Global Strategy; United States
    • 14 Jul 2020
    • Research & Ideas

    Restarting Under Uncertainty: Managerial Experiences from Around the World

    proactive effort to be as effective and clear as possible in their communication to both internal and external stakeholders. Importantly, a vast majority of the initiatives that companies in our sample are implementing do not require... View Details
    Keywords: by Raffaella Sadun, Andrea Bertoni, Alexia Delfino, Giovanni Fassio, and Mariapaola Testa
    • 22 Mar 2024
    • Blog Post

    Driving Impact in Emerging Markets with HBS Alum Nneka Chime (MBA 2015)

    contributing to her home country. She noticed that many of the families she grew up with eventually found themselves dispersed around the globe after seeking opportunities abroad. While she welcomed international exposure, traveling to... View Details
    • 08 Feb 2000
    • Research & Ideas

    Building Effective R&D Capabilities Abroad

    Because he knew the company inside and out—from central research and development to international marketing—the team reasoned that he would be able to bring the new laboratory up to speed quickly by drawing on resources from various... View Details
    Keywords: by Walter Kuemmerle
    • 19 Jul 2023
    • Blog Post

    A Pathway to Pursue Aspirations

    really attracted to its mission to help children grow smarter, stronger, and kinder – especially the kinder part in this current age.” Although she hasn’t discussed specific projects yet, Mizuho will serve as Director of Strategy for View Details
    • 02 Apr 2007
    • Lessons from the Classroom

    Making the Move to General Manager

    integration. The cases also focus on general managers from companies around the globe in an effort to mirror the international mix of participants. "We try to have cases that reflect the people in the group. More importantly, we... View Details
    Keywords: by Martha Lagace
    • 06 Mar 2020
    • Book

    A Great Teacher's Lessons for Leading

    content. At the same time, I’m managing my own internal dialogue about whether we are moving in the right direction. Maybe there’s a student who looks disengaged. There’s a student who’s emotional. There’s a student who has her hand up... View Details
    Keywords: by Martha Lagace; Education