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  • 2021
  • Working Paper

Regulatory Approval and Expanded Market Size

By: Benjamin Berger, Amitabh Chandra and Craig Garthwaite
Regulatory review of new medicines is often viewed as a hindrance to innovation by increasing the hurdle to bring products to market. However, a more complete accounting of regulation must also account for its potential market expanding effects through quality... View Details
Keywords: New Medicines; Regulatory Approval; Health Care and Treatment; Research and Development; Governing Rules, Regulations, and Reforms; Markets; Expansion; Pharmaceutical Industry
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  • 2018
  • Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details
Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly
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  • 01 Dec 2023
  • News

Wide Horizon

home in Dallas to his parents’ place in Ruston, Louisiana, the small town of about 22,000 where he grew up. While there, the kids, then two and three years old, started running a fever, which would eventually register around 104 degrees. After finding a quick View Details
Keywords: Dan Morrell; Photos by Sarah Wilson
  • 2021
  • Working Paper

The Health Costs of Cost-Sharing

By: Amitabh Chandra, Evan Flack and Ziad Obermeyer
We use the design of Medicare’s prescription drug benefit program to demonstrate three facts about the health consequences of cost-sharing. First, we show that an as-if-random increase of 33.6% in out-of-pocket price (11.0 percentage points (p.p.) change in... View Details
Keywords: Cost-sharing; Impact; Health Care and Treatment; Insurance; Health; Consumer Behavior
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  • 2013
  • Working Paper

Increased Speed Equals Increased Wait: The Impact of a Reduction in Emergency Department Ultrasound Order Processing Time

By: Jillian Berry Jaeker, Anita L. Tucker and Michael H. Lee
We exploit an exogenous process change at two emergency departments (EDs) within a health system to test the theory that increasing capacity in a discretionary work setting increases wait times due to additional services being provided to customers as a consequence of... View Details
Keywords: Technology; Demand and Consumers; Service Delivery; Health Care and Treatment; Business Processes; Health Industry
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  • Web

Key Concepts - Institute For Strategy And Competitiveness

Integration Clinically integrate care across separate units and facilities using an IPU structure. Geography of Care Increase the geographic reach of leading providers in their... View Details
  • September 2017 (Revised February 2018)
  • Case

Becton Dickinson: Global Health Strategy

By: Mark R. Kramer and Sarah Mehta
Becton, Dickinson and Company (BD) was a medical technology firm headquartered in Franklin Lakes, New Jersey, with 43,000 employees and 2016 revenues of $12.5 billion. For several years, the company had pursued developing products that created shared value, defined as... View Details
Keywords: Shared Value; Creating Shared Value; Odon Device; Medical Technology; Value Creation; Values and Beliefs; Philanthropy and Charitable Giving; Health; Health Care and Treatment; Health Testing and Trials; Emerging Markets; Social Issues; Competitive Strategy; Medical Devices and Supplies Industry; Africa; Asia; Middle East
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  • Article

Front-line Staff Perspectives on Opportunities for Improving the Safety and Efficiency of Hospital Work Systems

By: Anita L. Tucker, Sara J. Singer, Jennifer E. Hayes and Alyson Falwell

Objective To link safety-related concerns raised by frontline staff about hospital work systems (operational failures) to the safety and efficiency of hospitals, and to contrast these concerns with national patient safety initiatives.

Data... View Details

Keywords: Perspective; Opportunities; Safety; Performance Efficiency; System; Failure; Conferences; Employees; Management Analysis, Tools, and Techniques; Experience and Expertise; Health Care and Treatment; Health Industry; United States
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  • Web

Information Technology - Institute For Strategy And Competitiveness

HBS ISC Health Care Health Care Value-Based Health Care Health Care Courses Fast Facts Value-Based Health Care... View Details
  • Web

Organizational Behavior - Faculty & Research

practitioners, enhance patient care, and seamlessly integrate into clinical workflows? The exact threshold of success was unclear, challenging Hillen to ensure the AI factory could continuously refine the technology to improve... View Details
  • 14 Jul 2009
  • First Look

First Look: July 14

horizontal preferences, distinct segments exist—each caring about innovation on only one attribute—and firms are a priori uncertain how many consumers each segment contains. In this case, a firm that conducts market research may follow a... View Details
Keywords: Martha Lagace
  • Web

Systems Integration - Institute For Strategy And Competitiveness

scheduling system. They also provided CHOP care for all children in the region at all times of the day, night and weekends through urgent care centers and a nurse run telephone... View Details
  • Web

Latin America - Global

supporting public schools serving over 40,000 students or by launching a community training center to meet urgent workforce development needs in the local energy sector. With Techint’s tradition of deep community engagement and rigorous... View Details
  • September 2009
  • Article

A Detailed Analysis of the Reduction Mammaplasty Learning Curve: A Statistical Process Model for Approaching Surgical Performance Improvement

By: Matthew Carty MD, Rodney Chan, Robert S. Huckman, Daniel C. Snow and Dennis Orgill

Background: The increased focus on quality and efficiency improvement within academic surgery has met with variable success among plastic surgeons. Traditional surgical performance metrics, such as morbidity and mortality, are insufficient to improve the... View Details

Keywords: Experience and Expertise; Health Care and Treatment; Medical Specialties; Outcome or Result; Performance Efficiency; Performance Improvement
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  • 01 Dec 2023
  • News

Joint Venture

health care venture of his own. Surakanti spent almost a year poring over tech research in search of a device with the potential to transform the treatment of a common health issue. Galene, under development at Duke University, stopped... View Details
Keywords: Shoshi Parks
  • 09 Jun 2015
  • First Look

First Look: June 9, 2015

In October 2013, Colgate-Palmolive Company, the world's leading oral care company, was about to launch its new Colgate® Maximum Cavity Protection plus Sugar Acid Neutralizer toothpaste in Brazil. The oral View Details
Keywords: Sean Silverthorne
  • March 2022
  • Article

Where to Locate COVID-19 Mass Vaccination Facilities?

By: Dimitris Bertsimas, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li and Alessandro Previero
The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new... View Details
Keywords: Vaccines; COVID-19; Health Care and Treatment; Health Pandemics; Performance Effectiveness; Analytics and Data Science; Mathematical Methods
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  • 14 Jul 2023
  • Blog Post

Harvard Business School Announces Its 2023-2024 Blavatnik Fellows

Patrick will focus on product and research development at Raia Health with the goal of using AI-driven supported care to reduce patient-related symptom load and improve treatment completion for anti-cancer medications. Patrick earned a... View Details
  • 02 Apr 2013
  • First Look

First Look: April 2

  Publications 2006 Nature Reviews Beyond Magic Bullets: True Innovation in Health Care By: Narayan, Vaibhav A., Marco Mohwinckel, Gary Pisano, Michael Yang, and Husseini Manji Abstract—The molecular medicine revolution-based on advances... View Details
Keywords: Sean Silverthorne
  • Web

Entrepreneurship - Faculty & Research

algorithms to analyze thermal images and detect tumors. Its patented solution leveraged big data analytics, AI, and ML for reliable, early, and accurate breast cancer screening. Early clinical trials showed that the solution was equal to... View Details