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  • Article

Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting

By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
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  • September 2020
  • Article

Regulatory Sandboxes: A Cure for mHealth Pilotitis?

By: Abhishek Bhatia, Rahul Matthan, Tarun Khanna and Satchit Balsari
Mobile health (mHealth) and related digital health interventions in the past decade have not always scaled globally as anticipated earlier despite large investments by governments and philanthropic foundations. The implementation of digital health tools has suffered... View Details
Keywords: COVID-19; mHealth; Digital Health; Design Thinking; Regulation; Intervention; Regulatory Sandbox; Health Care and Treatment; Technological Innovation; Design; Governing Rules, Regulations, and Reforms; India
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  • Article

Front-line Staff Perspectives on Opportunities for Improving the Safety and Efficiency of Hospital Work Systems

By: Anita L. Tucker, Sara J. Singer, Jennifer E. Hayes and Alyson Falwell

Objective To link safety-related concerns raised by frontline staff about hospital work systems (operational failures) to the safety and efficiency of hospitals, and to contrast these concerns with national patient safety initiatives.

Data... View Details

Keywords: Perspective; Opportunities; Safety; Performance Efficiency; System; Failure; Conferences; Employees; Management Analysis, Tools, and Techniques; Experience and Expertise; Health Care and Treatment; Health Industry; United States
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  • Web

Accounting & Management - Faculty & Research

two operational pillars: data-driven decision-making and prioritization. Using BMC’s experience as an illustrative case, the article outlines six strategic choices healthcare leaders must make to translate intention into impact. Early results from BMC include... View Details
  • 2021
  • Working Paper

Regulatory Approval and Expanded Market Size

By: Benjamin Berger, Amitabh Chandra and Craig Garthwaite
Regulatory review of new medicines is often viewed as a hindrance to innovation by increasing the hurdle to bring products to market. However, a more complete accounting of regulation must also account for its potential market expanding effects through quality... View Details
Keywords: New Medicines; Regulatory Approval; Health Care and Treatment; Research and Development; Governing Rules, Regulations, and Reforms; Markets; Expansion; Pharmaceutical Industry
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  • 2018
  • Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details
Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly
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  • 01 Dec 2023
  • News

Wide Horizon

There were three critical events that led John Rodakis (MBA 1997) to form the nonprofit N of One in 2014 and ultimately dedicate his life to surfacing breakthrough autism research. The first occurred on Thanksgiving of 2012. He had driven about four hours with his wife... View Details
Keywords: Dan Morrell; Photos by Sarah Wilson
  • September 2017 (Revised February 2018)
  • Case

Becton Dickinson: Global Health Strategy

By: Mark R. Kramer and Sarah Mehta
Becton, Dickinson and Company (BD) was a medical technology firm headquartered in Franklin Lakes, New Jersey, with 43,000 employees and 2016 revenues of $12.5 billion. For several years, the company had pursued developing products that created shared value, defined as... View Details
Keywords: Shared Value; Creating Shared Value; Odon Device; Medical Technology; Value Creation; Values and Beliefs; Philanthropy and Charitable Giving; Health; Health Care and Treatment; Health Testing and Trials; Emerging Markets; Social Issues; Competitive Strategy; Medical Devices and Supplies Industry; Africa; Asia; Middle East
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  • Web

Latin America - Global

Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D) By: Linda A. Hill and Lydia Begag This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights... View Details
  • 2021
  • Working Paper

The Health Costs of Cost-Sharing

By: Amitabh Chandra, Evan Flack and Ziad Obermeyer
We use the design of Medicare’s prescription drug benefit program to demonstrate three facts about the health consequences of cost-sharing. First, we show that an as-if-random increase of 33.6% in out-of-pocket price (11.0 percentage points (p.p.) change in... View Details
Keywords: Cost-sharing; Impact; Health Care and Treatment; Insurance; Health; Consumer Behavior
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  • 2013
  • Working Paper

Increased Speed Equals Increased Wait: The Impact of a Reduction in Emergency Department Ultrasound Order Processing Time

By: Jillian Berry Jaeker, Anita L. Tucker and Michael H. Lee
We exploit an exogenous process change at two emergency departments (EDs) within a health system to test the theory that increasing capacity in a discretionary work setting increases wait times due to additional services being provided to customers as a consequence of... View Details
Keywords: Technology; Demand and Consumers; Service Delivery; Health Care and Treatment; Business Processes; Health Industry
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  • Web

Key Concepts - Institute For Strategy And Competitiveness

Integration Clinically integrate care across separate units and facilities using an IPU structure. Geography of Care Increase the geographic reach of leading providers in their... View Details
  • Web

Systems Integration - Institute For Strategy And Competitiveness

scheduling system. They also provided CHOP care for all children in the region at all times of the day, night and weekends through urgent care centers and a nurse run telephone... View Details
  • September 2009
  • Article

A Detailed Analysis of the Reduction Mammaplasty Learning Curve: A Statistical Process Model for Approaching Surgical Performance Improvement

By: Matthew Carty MD, Rodney Chan, Robert S. Huckman, Daniel C. Snow and Dennis Orgill

Background: The increased focus on quality and efficiency improvement within academic surgery has met with variable success among plastic surgeons. Traditional surgical performance metrics, such as morbidity and mortality, are insufficient to improve the... View Details

Keywords: Experience and Expertise; Health Care and Treatment; Medical Specialties; Outcome or Result; Performance Efficiency; Performance Improvement
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  • 14 Jul 2009
  • First Look

First Look: July 14

horizontal preferences, distinct segments exist—each caring about innovation on only one attribute—and firms are a priori uncertain how many consumers each segment contains. In this case, a firm that conducts market research may follow a... View Details
Keywords: Martha Lagace
  • Web

Information Technology - Institute For Strategy And Competitiveness

HBS ISC Health Care Health Care Value-Based Health Care Health Care Courses Fast Facts Value-Based Health Care... View Details
  • 14 Nov 2017
  • First Look

New Research and Ideas: November 14, 2017

expensive. How can health care organizations change this? One key is to prioritize quality improvement over cost cutting. By harnessing IT to help design better clinical practices, it’s possible to achieve... View Details
Keywords: Carmen Nobel
  • 07 Feb 2024
  • News

The Sound of Success

A groundbreaking gene therapy developed by Akouos, Inc., a precision genetic medicine company founded in 2016 by Emmanuel (Manny) Simons (MBA 2012), has enabled an 11-year-old boy from Morocco to hear sounds for the first time. According to a recent New York Times... View Details
  • 01 Dec 2023
  • News

Joint Venture

health care venture of his own. Surakanti spent almost a year poring over tech research in search of a device with the potential to transform the treatment of a common health issue. Galene, under development at Duke University, stopped... View Details
Keywords: Shoshi Parks
  • 14 Jul 2023
  • Blog Post

Harvard Business School Announces Its 2023-2024 Blavatnik Fellows

Patrick will focus on product and research development at Raia Health with the goal of using AI-driven supported care to reduce patient-related symptom load and improve treatment completion for anti-cancer medications. Patrick earned a... View Details