Publications

February 2021
Case

Digital Manufacturing at Amgen

By: Shane Greenstein, Kyle R. Myers and Sarah Mehta

This case discusses efforts made by biotechnology (biotech) company Amgen to introduce digital technologies into its manufacturing processes. Doing so is complicated by the fact that the process for manufacturing biologics—or therapeutics made from living cells—is... View Details

January 2023
Case

Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

By: Regina Herzlinger and Brian Walker

What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details

Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry

31 Jan 2014
News

Body, Heal Thyself

BANCEL Throughout 2009 and 2010, Stéphane Bancel (MBA 2000) had received upward of 20 calls from biotech companies asking him to come aboard and lead the company. It made sense. He was a highly recruited CEO successfully running... View Details

Keywords: Maureen Harmon; biotech; Health, Social Assistance; Scientific Research and Development Services

22 Oct 2013
First Look

First Look: October 22

expenditures on teammates lead to better performance in both sports teams in Canada and pharmaceutical sales teams in Belgium. These results suggest that a minor adjustment to employee bonuses-shifting the focus from the self to... View Details

Keywords: Sean Silverthorne

2010
Working Paper

Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe

By: Christopher C. Liu and Toby E. Stuart

In innovative industries, private-sector companies increasingly are participants in open communities of science and technology. To participate in the system of exchange in such communities, firms often publicly disclose what would otherwise remain private discoveries.... View Details

Keywords: For-Profit Firms; Higher Education; Information Publishing; Innovation and Invention; Science-Based Business; Social and Collaborative Networks; Boundaries; Pharmaceutical Industry; Pharmaceutical Industry

Read Now

21 Nov 2006
First Look

First Look: November 21, 2006

cost to identify and investigate. The Effect of File Sharing on Record Sales: An Empirical Analysis Authors:Felix Oberholzer-Gee and Koleman Strumpf Periodical:Journal of Political Economy (forthcoming) Abstract For industries ranging from software to View Details

Keywords: Sean Silverthorne

15 Jun 2007
Research & Ideas

Remembering Alfred Chandler

economic life. Chandler always stressed the importance of knowledge and learning inside organizations, which preceded more recent notions of the knowledge company or organizational learning. He was also a model intellectual, a scholar's... View Details

Keywords: by Sean Silverthorne

07 Oct 2014
First Look

First Look: October 7

Results from a Natural Field Experiment in California By: Levine, David I., and Michael W. Toffel Abstract—For companies with strong internal occupational safety and health auditing programs, OSHA inspections might seem a formality that... View Details

Keywords: Sean Silverthorne

15 Jan 2013
First Look

First Look: January 15

KnoopHarvard Business School Case 813-091 Amylin Pharmaceuticals brought two first-in-class diabetes drugs to market, Byetta and Symlin, in 2005, which were sold in over 80 countries with $650.7 million in sales by 2011. However, the... View Details

Keywords: Sean Silverthorne

Web

2024 Reunion Presentations - Alumni

a software company that encourages households to reduce their energy consumption. From Opower's earliest days, its managers utilized experiments to amplify their environmental impact and enhance customer value. We will revisit some of... View Details

May 2012 (Revised August 2014)
Case

McKesson

By: Regina E. Herzlinger and Natalie Kindred

McKesson, a large, diversified drug distribution and health care IT company, is considering development of new business offerings to help private practice physicians remain independent. The company, with $122 billion in 2010 revenues, just made its first foray into... View Details

Keywords: Health Care Industry; Health Care Policy; Organizational Transformations; Health Services; Health Care and Treatment; Business Model; Service Operations; Change Management; Corporate Strategy; Information Technology; Policy; Pharmaceutical Industry; Pharmaceutical Industry; United States