Publications

20 Mar 2012
First Look

Market Governments—Qualitative Evidence from a Biotechnology Multinational Authors:Prithwiraj Choudhury, James Geraghty, and Tarun Khanna Publication:Global Strategy Journal 2, no. 1 (February 2012) Abstract We build on the emerging... View Details

Keywords: Sean Silverthorne

September 2012 (Revised January 2014)
Case

Aqua Bounty

By: Lucy White and Stephen Burn-Murdoch

Valuation of a pre-revenue biotech company at IPO using probability trees and real option techniques. Company is based in Massachusetts and lists in London on AIM. Products are genetically-modified fast-growing salmon for fish farmers and disease-prevention drugs and... View Details

Keywords: IPO; Valuation; Real Options; Decision Tree; Biotech; Genetically Modified; Salmon; Entrepreneurship; Finance; Biotechnology Industry; Biotechnology Industry; North and Central America; Europe; South America

September 2000
Case

Novartis Agricultural Discovery Institute (A)

Steve Briggs, a PhD biologist, is asked to propose a strategy to take global life-science giant Novartis into the rapidly expanding field of plant genomics. View Details

Keywords: Design; Plant-Based Agribusiness; Genetics; Infrastructure; Biotechnology Industry; Biotechnology Industry

April 1998 (Revised June 1998)
Supplement

Pioneer Hi-Bred International, Inc.: Supply Management (Addendum)

By: Francis Aguilar, Paul Clark and Xin Xi He

Addendum to case. View Details

Keywords: Biotechnology Industry; Biotechnology Industry

October 1998 (Revised December 1999)
Case

Gene Research, the Mapping of Life and the Global Economy

By: Ray A. Goldberg and Juan Enriquez-Cabot

A new firm is being created to speed up the process of mapping humans, animals, and plants by combining gene technology with rapid gene identification to improve the health and well being of the human population and the productivity of crops and animals. How does one... View Details

Keywords: Information Technology; Organizational Structure; Technological Innovation; Business Processes; Health Care and Treatment; Performance Productivity; Welfare; Agribusiness; Genetics; Science-Based Business; Biotechnology Industry; Biotechnology Industry

03 Nov 2015
First Look

November 3, 2015

quantify the impact of scientific grant funding at the National Institutes of Health (NIH) on patenting by pharmaceutical and biotechnology firms. Our paper makes two contributions. First, we use newly constructed bibliometric data to... View Details

Keywords: Sean Silverthorne

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Biotechnology; Biotechnology; Biotechnology; Biotechnology

24 Sep 2007
Research & Ideas

The FDA: What Will the Next 100 Years Bring?

The U.S. Food and Drug Administration, which was created by the passage of the 1906 Federal Food and Drugs Act, regulates companies and industries accounting for one-quarter of all consumer spending, roughly $1.5 trillion worth of consumer goods and medicines. It... View Details

Keywords: by Sean Silverthorne; Biotechnology; Biotechnology; Biotechnology; Biotechnology

17 Oct 2012
Research & Ideas

America Needs a Manufacturing Renaissance

innovation process, but it is not the whole thing. Innovation is about moving the idea from concept to the customer's hands. For some highly complex products (flat-panel displays, PV cells, and biotechnology drugs, to name a few) the... View Details

Keywords: by Gary P. Pisano & Willy C. Shih; Manufacturing

Research Summary

Overview

By: Kyle R. Myers

Professor Myers studies the economics of what determines the rate and direction of innovation. He has examined the reallocation of scientists through the use of targeted research grants at the National Institutes of Health, and is working to further understand how... View Details

13 Jun 2005
Research & Ideas

From Turf Wars to Learning Curves: How Hospitals Adopt New Technology

in many cases, perform identical procedures in two or more hospitals during the course of a given week. We have found that this movement has negative effects on the degree to which surgeons are able to leverage their prior experience to improve future performance. We... View Details

Keywords: by Sara Grant; Health

23 Oct 2018
First Look

New Research and Ideas, October 23, 2018

Purchase this case:https://hbsp.harvard.edu/product/219030-PDF-ENG Harvard Business School Case 318-082 Sandra Brown Goes Digital (A): The Promise and Perils of Social Movements in a Healthcare Company As a middle manager at a View Details

Keywords: Dina Gerdeman

Sep 2011 - 2011
Conference Presentation

From Farms to Fuel Tanks: Collective Actors and New-venture Innovation in the U.S. Biodiesel Sector

By: Shon R. Hiatt

Keywords: Innovation and Invention; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry

July 2014 (Revised January 2017)
Course Overview Note

Building Life Science Businesses Spring Term 2017: Course Outline and Syllabus

By: Richard G. Hamermesh

This Course Outline and Syllabus gives an overview of the Spring 2016 class Building Life Science Businesses.7 View Details

Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Asia; North America; Europe

July 2013
Case

Novozymes: Establishing the Cellulosic Ethanol Value Chain

By: Willy Shih and Sen Chai

As the world's largest producer of industrial enzymes, Novozymes had invested heavily for many years to bio-engineer enzymes that could break down cellulose into fermentable sugar. In 2010, the company had launched what it thought would become a breakthrough product... View Details

Article

What to Know About Locating in a Cluster

By: Willy C. Shih and Sen Chai

As a study of two industry clusters in Denmark shows, factors that can make clusters attractive—easy people movement and knowledge spillovers—can also make it harder for individual companies to retain proprietary knowledge. View Details

Keywords: Clusters; Clustering; Competitiveness; Life Sciences; Telecommunications; Science-based; Research And Development; Industry Clusters; Research; Innovation Strategy; Innovation and Management; Geographic Location; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Denmark

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February 2014
Case

BGI: Data-driven Research

By: Willy Shih and Sen Chai

BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details

September 2009 (Revised December 2009)
Supplement

Genzyme Center (C)

By: Michael W. Toffel and Aldo Sesia

Genzyme Corporation is in the midst of planning its new corporate headquarters, which incorporates many innovative green building features. After learning that the building as planned would likely earn a LEED Silver rating, an intermediate score in the LEED green... View Details

Keywords: Environmental Sustainability; Corporate Social Responsibility and Impact; Standards; Cost vs Benefits; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry

September 2009 (Revised December 2009)
Supplement

Genzyme Center (B)

By: Michael W. Toffel and Aldo Sesia

Genzyme Corporation is in the midst of planning its new corporate headquarters, which incorporates many innovative green building features. After learning that the building as planned would likely earn a LEED Silver rating, an intermediate score in the LEED green... View Details

Keywords: Environmental Sustainability; Corporate Social Responsibility and Impact; Standards; Cost vs Benefits; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry