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Show Results For
- All HBS Web
(2,517)
- People (6)
- News (578)
- Research (1,754)
- Events (11)
- Multimedia (14)
- Faculty Publications (1,389)
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- February 2024
- Case
Compass Pathways: Pioneering Psychedelic Treatment
By: Tiona Zuzul, Kisha Lashley and Gamze Yucaoglu
This case follows Compass Pathways, a pioneering company developing treatment for depression based on psilocybin, the compound found in ‘magic mushrooms.’ Psilocybin was a federally illegal substance in the U.S., and a “Schedule I” drug, defined as a drug “with no... View Details
Keywords: Commercialization; Corporate Strategy; Competitive Strategy; Product Launch; Health Testing and Trials; Research and Development; Laws and Statutes; Pharmaceutical Industry; Europe; United States; United Kingdom
Zuzul, Tiona, Kisha Lashley, and Gamze Yucaoglu. "Compass Pathways: Pioneering Psychedelic Treatment." Harvard Business School Case 724-412, February 2024.
- February 2014
- Article
Developing a System to Track Meaningful Outcome Measures in Head and Neck Cancer Treatment
By: Ronald S. Walters, Heidi W. Albright, Randal S. Weber, Thomas W. Feeley, Ehab Y. Hanna, Scott B. Cantor, Carol M. Lewis and Thomas W. Burke
The health care industry, including consumers, providers, and payers of health care, recognize the importance of developing meaningful, patient-centered measures. This article describes our experience using an existing electronic medical record largely based on free... View Details
Keywords: Cancer Treatment; Cancer Care In The U.S.; Outcomes Measurement; Health Care and Treatment; Measurement and Metrics; Health Industry; North and Central America
Walters, Ronald S., Heidi W. Albright, Randal S. Weber, Thomas W. Feeley, Ehab Y. Hanna, Scott B. Cantor, Carol M. Lewis, and Thomas W. Burke. "Developing a System to Track Meaningful Outcome Measures in Head and Neck Cancer Treatment." Head & Neck 36, no. 2 (February 2014): 226–230. (e-Pub 6/2013. PMID: 23729280.)
- 2024
- Working Paper
Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a chance discovery of bacteria that infect stomach linings completely changed how physicians treat ulcers. Specifically, we chronicle how: 1) two Australian physicians brought the bacterial infection to the world’s attention and... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-006, July 2019. (Revised May 2024.)
- 2024
- Article
Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules
By: Michael Lingzhi Li and Kosuke Imai
A century ago, Neyman showed how to evaluate the efficacy of treatment using a randomized experiment under a minimal set of assumptions. This classical repeated sampling framework serves as a basis of routine experimental analyses conducted by today’s scientists across... View Details
Li, Michael Lingzhi, and Kosuke Imai. "Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules." Journal of Causal Inference 12, no. 1 (2024).
- January 2007
- Article
A Randomized Clinical Trial of EMDR, Fluoxetine and Pill Placebo in the Treatment of PTSD: Treatment Effects and Long-term Maintenance
By: Bessel A. van der Kolk, Joseph Spinazzola, Margaret E. Blaustein, James Hopper, Elizabeth Hopper, Deborah Korn and William B. Simpson
van der Kolk, Bessel A., Joseph Spinazzola, Margaret E. Blaustein, James Hopper, Elizabeth Hopper, Deborah Korn, and William B. Simpson. "A Randomized Clinical Trial of EMDR, Fluoxetine and Pill Placebo in the Treatment of PTSD: Treatment Effects and Long-term Maintenance." Journal of Clinical Psychiatry 68, no. 1 (January 2007).
- 1995
- Chapter
The Tax Treatment of Interest and the Operations of U.S. Multinationals
By: Kenneth A. Froot
Keywords: Corporation Taxation; Interest Deductibility; Cost of Capital; Taxation; Financing and Loans; Corporate Finance
Froot, Kenneth A. "The Tax Treatment of Interest and the Operations of U.S. Multinationals." In Taxing Multinational Corporations, edited by M. Feldstein, J. Hines, and G. Hubbard, 81–93. University of Chicago Press, 1995.
- 02 Feb 2012
- Op-Ed
Once a Castle, Home is Now a Debtors’ Prison
We have created a housing hybrid in America, refashioning the single-family home into a mini debtors' prison. Almost 11 million dot the landscape. In Las Vegas and Phoenix, over 50 percent of homeowners live in one. “Understandably, most... View Details
- 1995
- Chapter
The Tax Treatment of Interest and the Operations of U.S. Multinationals
By: K. Froot and J. Hines
Froot, K., and J. Hines. "The Tax Treatment of Interest and the Operations of U.S. Multinationals." In Taxing Multinational Corporations, edited by M. Feldstein, J. Hines, and G. Hubbard, 81–93. University of Chicago Press, 1995.
- Article
Some Reflections on the Antitrust Treatment of Intellectual Property
By: Tracy R. Lewis and Dennis A. Yao
Abridged version in The Financial Times, The Complete MBA Companion, 1997, pp. 577-582. View Details
Lewis, Tracy R., and Dennis A. Yao. "Some Reflections on the Antitrust Treatment of Intellectual Property." Antitrust Law Journal 63, no. 2 (1995): 603–619. (Abridged version in The Financial Times, The Complete MBA Companion, 1997, pp.577-582. Harvard users click here for full text.)
- September 2022
- Article
Cost of Cardiac Stereotactic Body Radioablation Therapy versus Catheter Ablation for Treatment of Ventricular Tachycardia
By: Chen Wei, Michelle Boeck, Pierre C. Qian, Todd Vivenzio, Zoe Elizee, Jeremy S. Bredfeldt, Robert S. Kaplan, Usha Tedrow, Raymond Mak and Paul C. Zei
Cardiac SBRT is a novel way of treating refractory ventricular tachycardia (VT) that may be less costly than catheter ablation, owing to its noninvasive, outpatient nature. We applied time-driven activity-based costing to both procedures. The direct and total... View Details
Wei, Chen, Michelle Boeck, Pierre C. Qian, Todd Vivenzio, Zoe Elizee, Jeremy S. Bredfeldt, Robert S. Kaplan, Usha Tedrow, Raymond Mak, and Paul C. Zei. "Cost of Cardiac Stereotactic Body Radioablation Therapy versus Catheter Ablation for Treatment of Ventricular Tachycardia." Pacing and Clinical Electrophysiology 45, no. 9 (September 2022): 1005–1179.
- 2007
- Working Paper
Taxes and Portfolio Choice: Evidence from JGTRRA's Treatment of International Dividends
By: Mihir A. Desai and Dhammika Dharmapala
This paper investigates how taxes influence portfolio choices by exploring the response to the distinctive treatment of foreign dividends in the Jobs and Growth Tax Relief Reconciliation Act (JGTRRA). JGTRRA lowered the dividend tax rate to 15% for American equities... View Details
- January 2020
- Article
One of a Kind: The Strong and Complex Preference for Unique Treatment from Romantic Partners
By: Lalin Anik and Ryan Hauser
Individuals prefer romantic partners who universally treat others well (i.e., partners who exhibit trait-level generosity) and also prefer partners who treat them uniquely. Previous work supports both preferences, yet the literature has largely ignored what happens... View Details
Anik, Lalin, and Ryan Hauser. "One of a Kind: The Strong and Complex Preference for Unique Treatment from Romantic Partners." Journal of Experimental Social Psychology 86 (January 2020).
- January 19, 2024
- Article
Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder
By: Robert S. Kaplan and Sarah E. Wakeman
U.S. overdose deaths currently exceed 100,000 per year. New facilities, known as bridge clinics, are broadening access to high-quality care by offering outpatient substance use disorder (SUD) treatment with few access barriers. But many of the critical services offered... View Details
Kaplan, Robert S., and Sarah E. Wakeman. "Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder." Health Affairs Forefront (January 19, 2024).
- June 2012
- Teaching Note
Cancer Treatment Centers of America: Scaling the Mother Standard of Care (TN)
By: Rosabeth Moss Kanter and Matthew Bird
- 2022
- Article
Regulatory Treatment of Changes in Fair Value and the Composition of Banks' Investment Portfolios
By: Michael Iselin, Jung Koo Kang and Joshua Madsen
In their implementation of Basel III, U.S. bank regulators are again including changes in the fair value of available-for-sale (AFS) debt securities in Tier 1 capital, but only for the largest U.S. banks. This paper investigates a potential impact of expanding this... View Details
Keywords: Fair Value Accounting; SFAS 115; Basel III; Governing Rules, Regulations, and Reforms; Banks and Banking; Debt Securities; Credit; Risk and Uncertainty; Investment Portfolio; Decision Making; Banking Industry; United States
Iselin, Michael, Jung Koo Kang, and Joshua Madsen. "Regulatory Treatment of Changes in Fair Value and the Composition of Banks' Investment Portfolios." Journal of Financial Reporting 7, no. 1 (2022): 123–143.
- 2011
- Working Paper
Free to Punish? The American Dream and the Harsh Treatment of Criminals
By: Rafael Di Tella and Juan Dubra
We describe the evolution of selective aspects of punishment in the U.S. over the period 1980-2004. We note that imprisonment increased around 1980, a period that coincides with the "Reagan revolution" in economic matters. We build an economic model where beliefs about... View Details
Keywords: Crime and Corruption; Economy; Moral Sensibility; Mathematical Methods; Opportunities; Behavior; United States
Di Tella, Rafael, and Juan Dubra. "Free to Punish? The American Dream and the Harsh Treatment of Criminals." NBER Working Paper Series, No. 17309, August 2011.
- February 2018
- Article
Development and Feasibility of Bundled Payments for the Multidisciplinary Treatment of Head and Neck Cancer: A Pilot Program
By: Tracy Spinks, Alexis Guzman, Beth M. Beadle, Seohyun Lee, Ron Walters, Jim Incalcaterra, Ehab Hanna, Amy Hessel, Randal Weber, Sandra Denney, Lee Newcomer and Thomas W. Feeley
Purpose:
Despite growing interest in bundled payments to reduce the costs of care, this payment method remains largely untested in cancer. This 3-year pilot tested the feasibility of a 1-year bundled payment for the multidisciplinary treatment of head and neck... View Details
Spinks, Tracy, Alexis Guzman, Beth M. Beadle, Seohyun Lee, Ron Walters, Jim Incalcaterra, Ehab Hanna, Amy Hessel, Randal Weber, Sandra Denney, Lee Newcomer, and Thomas W. Feeley. "Development and Feasibility of Bundled Payments for the Multidisciplinary Treatment of Head and Neck Cancer: A Pilot Program." Journal of Oncology Practice 14, no. 2 (February 2018): e103–e121.
- April 2017
- Case
Luminopia: Improving Treatment for Visual Disorders
By: Doug J. Chung and Sarah Mehta
Luminopia—a start-up founded in January 2016 by three Harvard College freshmen—uses virtual reality technology to treat amblyopia (more commonly called “lazy eye”), the single biggest cause of visual disorders among children. By February 2017, the three founders had... View Details
Keywords: Pricing; Virtual Reality; Startup; Marketing; Marketing Channels; Product Marketing; Product Launch; Product Positioning; Business Startups; Price; Medical Devices and Supplies Industry; Cambridge; Massachusetts; United States
Chung, Doug J., and Sarah Mehta. "Luminopia: Improving Treatment for Visual Disorders." Harvard Business School Case 517-065, April 2017.
- April 2020
- Article
Designs for Estimating the Treatment Effect in Networks with Interference
By: Ravi Jagadeesan, Natesh S. Pillai and Alexander Volfovsky
In this paper, we introduce new, easily implementable designs for drawing causal inference from randomized experiments on networks with interference. Inspired by the idea of matching in observational studies, we introduce the notion of considering a treatment... View Details
Keywords: Experimental Design; Network Inference; Neyman Estimator; Symmetric Interference Model; Homophily
Jagadeesan, Ravi, Natesh S. Pillai, and Alexander Volfovsky. "Designs for Estimating the Treatment Effect in Networks with Interference." Annals of Statistics 48, no. 2 (April 2020): 679–712.
- Global Healthcare 2002
- Article
Disruptive Innovation -- New Diagnosis and Treatment for the Systemic Maladies of Healthcare
By: John W. Kenagy and Clayton M. Christensen
Kenagy, John W., and Clayton M. Christensen. "Disruptive Innovation -- New Diagnosis and Treatment for the Systemic Maladies of Healthcare." World Markets Series, Business Briefing (Global Healthcare 2002): 14–17.