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- Faculty Publications (327)
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- All HBS Web
(2,040)
- Faculty Publications (327)
- April 2024 (Revised November 2024)
- Case
Moderna: Pioneering a People Platform to Accelerate Science Innovation
By: Tatiana Sandino, Emil Dy and Samuel Grad
Moderna was founded in 2010 to explore how messenger ribonucleic acid (mRNA) could be used to create breakthrough medicines by encoding instructions for the body to create antibodies. When Stéphane Bancel (HBS 2000) took over in 2011, he bet on the potential of this... View Details
Keywords: Disruptive Innovation; Talent and Talent Management; Selection and Staffing; AI and Machine Learning; Digital Strategy; Innovation and Management; Leadership Development; Management Practices and Processes; Management Systems; Organizational Culture; Performance Evaluation; Alignment; Employee Relationship Management; Science-Based Business; Expansion; Pharmaceutical Industry; Biotechnology Industry; United States
Sandino, Tatiana, Emil Dy, and Samuel Grad. "Moderna: Pioneering a People Platform to Accelerate Science Innovation." Harvard Business School Case 124-091, April 2024. (Revised November 2024.)
- 2024
- Working Paper
Appropriate Entrepreneurship? The Rise of China and the Developing World
By: Josh Lerner, Junxi Liu, Jacob Moscona and David Yang
Global innovation and entrepreneurship has traditionally been dominated by a handful
of high-income countries, especially the US. This paper investigates the international
consequences of the rise of a new hub for innovation, focusing on the dramatic
growth of... View Details
Lerner, Josh, Junxi Liu, Jacob Moscona, and David Yang. "Appropriate Entrepreneurship? The Rise of China and the Developing World." Harvard Business School Working Paper, No. 24-061, March 2024.
- March 2024 (Revised May 2025)
- Case
Governing OpenAI (A)
By: Lynn S. Paine, Suraj Srinivasan and Will Hurwitz
In late November 2023, OpenAI’s new board of directors took stock of the situation. The company, which sought to develop artificial general intelligence (AGI)—computer systems with capabilities exceeding human abilities—was looking to regain its footing after a chaotic... View Details
Keywords: Artificial Intelligence; Board Of Directors; Board Decisions; Board Dynamics; Corporate Boards; Governance Changes; Governance Structure; Leadership Change; Legal Aspects Of Business; Nonprofit Governance; Strategy And Execution; Technological Change; AI and Machine Learning; Corporate Governance; Leadership; Management; Mission and Purpose; Technological Innovation; Governing Rules, Regulations, and Reforms; Governing and Advisory Boards; Resignation and Termination; Ethics; Nonprofit Organizations; Open Source Distribution; Partners and Partnerships; Technology Industry; San Francisco; United States
Paine, Lynn S., Suraj Srinivasan, and Will Hurwitz. "Governing OpenAI (A)." Harvard Business School Case 324-103, March 2024. (Revised May 2025.)
- February 2024 (Revised December 2024)
- Case
Best Buy Health: Enabling Care at Home
This case explores retailer Best Buy’s decision to enter health care. Best Buy Health aims to enable care at home across three prongs: consumer health, active aging, and virtual care. A key pillar of Best Buy Health's strategy is leveraging the Geek Squad—the company's... View Details
Keywords: Business Ventures; Health Care and Treatment; Innovation and Invention; Business Strategy; Market Entry and Exit; Service Delivery; Service Operations; Electronics Industry; Health Industry; Retail Industry; United States; Minnesota
Huckman, Robert S., Rosabeth Moss Kanter, Antonio Moreno, Bradley Staats, and Sarah Mehta. "Best Buy Health: Enabling Care at Home." Harvard Business School Case 624-009, February 2024. (Revised December 2024.)
- February 2024
- Article
Representation and Extrapolation: Evidence from Clinical Trials
By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
This article examines the consequences and causes of low enrollment of Black patients in clinical
trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is
more relevant for decision-making by physicians and patients when it... View Details
Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." Quarterly Journal of Economics 139, no. 1 (February 2024): 575–635.
- January 2024 (Revised August 2024)
- Case
Essex County Community Foundation: Pivot to Systems Philanthropy
By: V. Kasturi Rangan, Brian Trelstad and Courtney Han
2023 marked five years of the Essex County Community Foundation (ECCF)’s “systems philanthropy” approach to grantmaking. Located in northeastern Massachusetts, the community foundation served 800,000 residents across 34 cities and towns that varied widely by... View Details
Keywords: Philanthropy and Charitable Giving; Reputation; Civil Society or Community; Social Issues; Alignment; Nonprofit Organizations; Business and Stakeholder Relations; Collaborative Innovation and Invention; Leading Change; Massachusetts
Rangan, V. Kasturi, Brian Trelstad, and Courtney Han. "Essex County Community Foundation: Pivot to Systems Philanthropy." Harvard Business School Case 524-066, January 2024. (Revised August 2024.)
- 2024
- Book
The Everything Token: How NFTs and Web3 Will Transform the Way We Buy, Sell, and Create
By: Steve Kaczynski and Scott Duke Kominers
We demystify the coming digital revolution, showing how NFTs will transform our online and offline interactions.
NFTs aren’t just pictures on the internet, or a fad that has come and gone. Rather, they’re a new technology for creating digital assets and... View Details
NFTs aren’t just pictures on the internet, or a fad that has come and gone. Rather, they’re a new technology for creating digital assets and... View Details
Keywords: Economic Systems; Microeconomics; Entrepreneurship; Cultural Entrepreneurship; Information Technology; Innovation and Invention; Innovation Strategy; Digital Platforms; Digital Strategy; Digital Transformation; Internet and the Web; Technology Adoption; Marketing; Marketing Strategy; Product Marketing; Product Positioning; Markets; E-commerce; Market Design; Value; Customer Value and Value Chain; Collaborative Innovation and Invention; Innovation and Management; Organizational Structure; Customer Ownership; Ownership; Advertising Industry; Communications Industry; Computer Industry; Consumer Products Industry; Fashion Industry; Information Technology Industry; Media and Broadcasting Industry; Technology Industry; Web Services Industry
Kaczynski, Steve, and Scott Duke Kominers. The Everything Token: How NFTs and Web3 Will Transform the Way We Buy, Sell, and Create. Portfolio/Penguin, 2024.
- December 2023
- Case
TikTok: The Algorithm Will See You Now
By: Shikhar Ghosh and Shweta Bagai
In a world where attention is a scarce commodity, this case explores the meteoric rise of TikTok—an app that transformed from a niche platform for teens into the most visited domain by 2021—surpassing even Google. Its algorithm was a sophisticated mechanism for... View Details
Keywords: Social Media; Applications and Software; Disruptive Innovation; Business and Government Relations; International Relations; Cybersecurity; Culture; Technology Industry; China; United States; India
Ghosh, Shikhar, and Shweta Bagai. "TikTok: The Algorithm Will See You Now." Harvard Business School Case 824-125, December 2023.
- December 2023 (Revised January 2025)
- Case
Research In Motion: Launching and Scaling the World's First Smartphone Empire (A)
By: Tatiana Sandino and Samuel Grad
In 2005, Research In Motion’s (RIM) BlackBerry smartphone was a sensation. After its launch in 1999, the groundbreaking BlackBerry had captured the hearts and minds of corporate America through its secure wireless email service. The device was so addictive and... View Details
Keywords: Business Growth and Maturation; Decision Choices and Conditions; Mobile and Wireless Technology; Innovation and Management; Technological Innovation; Business or Company Management; Management Style; Product Development; Managerial Roles; Growth and Development Strategy; Technology Industry; United States; Canada
Sandino, Tatiana, and Samuel Grad. "Research In Motion: Launching and Scaling the World's First Smartphone Empire (A)." Harvard Business School Case 124-023, December 2023. (Revised January 2025.)
- November 2023
- Case
Open Source Machine Learning at Google
Set in early 2023, the case exposes students to the challenges of managing open source software at Google. The case focuses on the challenges for Alex Spinelli, Vice President of Product Management for Core Machine Learning. He must set priorities for Google’s efforts... View Details
Keywords: Decision Choices and Conditions; Technological Innovation; Open Source Distribution; Strategy; AI and Machine Learning; Applications and Software; Technology Industry; United States
Greenstein, Shane, Martin Wattenberg, Fernanda B. Viégas, Daniel Yue, and James Barnett. "Open Source Machine Learning at Google." Harvard Business School Case 624-015, November 2023.
- 2023
- Working Paper
Coordinated R&D Programs and the Creation of New Industries
By: Daniel P. Gross and Maria P. Roche
Complex systems technologies—including “deep tech”—are prone to numerous frictions that stymie commercial development. Yet technologies with these features underpin some of the most valuable industries of the past century. We examine how large, mission-oriented... View Details
Keywords: Research and Development; Policy; Business and Government Relations; Technological Innovation; Collaborative Innovation and Invention
Gross, Daniel P., and Maria P. Roche. "Coordinated R&D Programs and the Creation of New Industries." Harvard Business School Working Paper, No. 24-027, April 2023. (Revised October 2024.)
- October 2023 (Revised March 2024)
- Case
KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing
By: George Serafeim, Siko Sikochi and Namrata Arora
The problem was massive: two million hectares of African forests were lost annually to charcoal production for cooking, an area equivalent to 13 times Greater London, resulting in one billion tons of carbon emissions yearly. At the same time, an estimated 700,000... View Details
Keywords: Clean Tech; Digital; Carbon Credits; Carbon Offsetting; Africa; Emerging Markets; Energy; Climate Change; Entrepreneurship; Energy Sources; Environmental Sustainability; Health; Market Design; Business Startups; Transition; Environmental Regulation; Policy; Energy Industry; Consumer Products Industry; Africa; Kenya; Rwanda
Serafeim, George, Siko Sikochi, and Namrata Arora. "KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing." Harvard Business School Case 124-022, October 2023. (Revised March 2024.)
- October 2023
- Case
Fixie and Conversational AI Sidekicks
By: Jeffrey J. Bussgang and Carin-Isabel Knoop
In March 2023, Fixie Co-Founder and Chief Architect Matt Welsh and co-founders had the kind of meeting no founders want to have. The president of leading artificial intelligence (AI) research and deployment firm OpenAI, which had catapulted into fame with its ChatGPT... View Details
Keywords: Large Language Model; Entrepreneurship; Decision Choices and Conditions; AI and Machine Learning; Technological Innovation; Competitive Strategy; Technology Industry; United States
Bussgang, Jeffrey J., and Carin-Isabel Knoop. "Fixie and Conversational AI Sidekicks." Harvard Business School Case 824-037, October 2023.
- September 2023 (Revised September 2023)
- Teaching Note
Roche: Innovation and Access to Healthcare
By: George Serafeim
Teaching Note for HBS Case No. 123-075. In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to... View Details
- September 2023
- Case
FoodCloud: Tackling Food Insecurity and Climate Change in One Bite
By: Brian Trelstad and Emer Moloney
In 2013, Aoibheann O’Brien and Iseult Ward founded FoodCloud, a non-profit social enterprise that aimed to address food waste and food insecurity issues. Through its technology platform, Foodiverse, FoodCloud connected surplus food from retailers with community groups... View Details
Keywords: Nonprofit Organizations; Expansion; Technological Innovation; Environmental Sustainability; Social Issues; Growth and Development Strategy; Green Technology Industry; Agriculture and Agribusiness Industry; Food and Beverage Industry; Republic of Ireland; Europe
Trelstad, Brian, and Emer Moloney. "FoodCloud: Tackling Food Insecurity and Climate Change in One Bite." Harvard Business School Case 324-031, September 2023.
- September 2023
- Teaching Note
Apple’s iPhone Revolution: Pioneering the Circular Economy
By: George Serafeim
Teaching Note for HBS Case 123-089. The case describes the Trade-In system for iPhones that allow iPhones to be refurbished and reused or to be recycled. The case provides information for the students to analyze the financial attractiveness of the Trade-In system and... View Details
- September 2023 (Revised January 2024)
- Case
RightHand Robotics: Choosing the First Market
By: Thomas R. Eisenmann and Stacy Straaberg
In early 2015, RightHand Robotics’s (RHR) leadership faced a set of decisions in commercializing the startup’s robotic picking solution. RHR’s central product was the RightPick integrated robotic picking system which featured a robotic arm, a three-fingered robotic... View Details
Keywords: Business Startups; Market Entry and Exit; Product; Research and Development; Business Strategy; Commercialization; Information Infrastructure; Technological Innovation; Manufacturing Industry; Technology Industry; United States; Massachusetts
Eisenmann, Thomas R., and Stacy Straaberg. "RightHand Robotics: Choosing the First Market." Harvard Business School Case 824-006, September 2023. (Revised January 2024.)
- August 2023
- Article
Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel
By: Dylan Slack, Satyapriya Krishna, Himabindu Lakkaraju and Sameer Singh
Practitioners increasingly use machine learning (ML) models, yet models have become more complex and harder to understand. To understand complex models, researchers have proposed techniques to explain model predictions. However, practitioners struggle to use... View Details
Slack, Dylan, Satyapriya Krishna, Himabindu Lakkaraju, and Sameer Singh. "Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel." Nature Machine Intelligence 5, no. 8 (August 2023): 873–883.
- June 2023 (Revised June 2023)
- Supplement
Roche: Innovation and Access to Healthcare
By: George Serafeim
In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that had... View Details
Keywords: ESG (Environmental, Social, Governance) Performance; Sustainable Finance; Growth Strategy And Execution; Sustainability Targets; Impact Evaluation; Healthcare Access; Healthcare Innovation; Healthcare Systems; Healthcare Operations; Finance; Strategy; Health Testing and Trials; Health Care and Treatment; Growth Management; Measurement and Metrics; Innovation Strategy; Corporate Social Responsibility and Impact; Health Industry; Pharmaceutical Industry; Switzerland; North America; Europe; Asia; Latin America; Africa
Serafeim, George. "Roche: Innovation and Access to Healthcare." Harvard Business School Multimedia/Video Supplement 123-713, June 2023. (Revised June 2023.)
- April 2023 (Revised September 2023)
- Case
Levels: The Remote, Asynchronous, Deep Work Management System
By: Joseph B. Fuller and George Gonzalez
Levels is a highly innovative startup in the health care space. They intend to revolutionize health by linking behavior—eating, exercise, sleeping, etc.—to changes in metabolism. They believe metabolic health can be managed through careful monitoring of changes in... View Details
Keywords: Applications and Software; Business Startups; Organizational Culture; Management Style; Technology Industry; United States
Fuller, Joseph B., and George Gonzalez. "Levels: The Remote, Asynchronous, Deep Work Management System." Harvard Business School Case 323-069, April 2023. (Revised September 2023.)