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      • November 2024
      • Teaching Note

      Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams

      By: Debora L. Spar and Julia M. Comeau
      Teaching Note for HBS Case No. 323-039. In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At... View Details
      Keywords: Pharmaceutical Companies; Technological And Scientific Innovation; Organ Donation; Health Care and Treatment; Health Disorders; Innovation and Invention; Growth and Development Strategy; Product Development; Pharmaceutical Industry; Medical Devices and Supplies Industry; United States; District of Columbia
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      Spar, Debora L., and Julia M. Comeau. "Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams." Harvard Business School Teaching Note 325-058, November 2024.
      • 2024
      • Working Paper

      Categorical Processing in a Complex World

      By: Marco Sammon, Thomas Graeber and Christopher Roth
      In real-world news environments, quantitative information is rarely presented in isolation; it is characterized through qualitative comparisons with various reference levels. Company earnings, for example, are commonly compared to analyst forecasts, previous earnings,... View Details
      Keywords: Announcements; Cognition and Thinking; Communication Strategy
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      Sammon, Marco, Thomas Graeber, and Christopher Roth. "Categorical Processing in a Complex World." Working Paper, November 2024.
      • November 5, 2024
      • Article

      The International Empirics of Management

      By: Daniela Scur, Scott Ohlmacher, John Van Reenen, Morten Bennedsen, Nick Bloom, Ali Choudhary, Lucia Foster, Jesse Groenewegen, Arti Grover, Sjoerd Hardeman, Leonardo Iacovone, Ryo Kambayashi, Marie-Christine Laible, Renata Lemos, Hongbin Li, Andrea Linarello, Mika Maliranta, Denis Medvedev, Charlotte Meng, John Miles Touya, Natalia Mandirola, Roope Ohlsbom, Atsushi Ohyama, Megha Patnaik, Mariana Pereira-López, Raffaella Sadun, Tatsuro Senga, Franklin Qian and Florian Zimmermann
      A country’s national income broadly depends on the quantity and quality of workers and capital. But how well these factors are managed within and between firms may be a key determinant of a country’s productivity and its GDP. Although social scientists have long... View Details
      Keywords: Performance Productivity; Economy; Management Practices and Processes
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      Scur, Daniela, Scott Ohlmacher, John Van Reenen, Morten Bennedsen, Nick Bloom, Ali Choudhary, Lucia Foster, Jesse Groenewegen, Arti Grover, Sjoerd Hardeman, Leonardo Iacovone, Ryo Kambayashi, Marie-Christine Laible, Renata Lemos, Hongbin Li, Andrea Linarello, Mika Maliranta, Denis Medvedev, Charlotte Meng, John Miles Touya, Natalia Mandirola, Roope Ohlsbom, Atsushi Ohyama, Megha Patnaik, Mariana Pereira-López, Raffaella Sadun, Tatsuro Senga, Franklin Qian, and Florian Zimmermann. "The International Empirics of Management." Proceedings of the National Academy of Sciences 121, no. 45 (November 5, 2024).
      • October 18, 2024
      • Article

      Why Workplace Well-Being Programs Don’t Achieve Better Outcomes

      By: Jazz Croft, Acacia Parks and Ashley Whillans
      By 2026, global corporate spending on wellness programs is set to top $94.6 billion, yet anticipated improvements in well-being are not being realized, and, in fact, mental health needs are continuing to rise around the world. Drawing on a large body of recent... View Details
      Keywords: Organizational Culture; Employees; Well-being
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      Croft, Jazz, Acacia Parks, and Ashley Whillans. "Why Workplace Well-Being Programs Don’t Achieve Better Outcomes." Harvard Business Review Digital Articles (October 18, 2024).
      • October 16, 2024
      • Article

      Physicians Can Help Cut Costs. They Just Need the Right Incentives.

      By: Susanna Gallani and Derek A. Haas
      Health care organizations have long tried to enlist physicians in their effort to control or reduce costs. One effective means for doing so is to create an incentive system that rewards physicians for their contributions. To design such a system, organizations should... View Details
      Keywords: Cost; Motivation and Incentives; Compensation and Benefits; Health Industry
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      Gallani, Susanna, and Derek A. Haas. "Physicians Can Help Cut Costs. They Just Need the Right Incentives." Harvard Business Review Digital Articles (October 16, 2024).
      • September 20, 2024
      • Article

      It’s Time to Unbundle ESG

      By: Aaron K. Chatterji and Michael W. Toffel
      ESG is at an inflection point. It has come to represent a broad and inchoate aspiration for what business should be doing beyond maximizing shareholder value. With ESG advocates on the defensive, business leaders need a new roadmap to determine which factors to... View Details
      Keywords: ESG; ESG (Environmental, Social, Governance) Performance; ESG Ratings; ESG Reporting; ESG Disclosure; Sustainability; Climate; Climate Finance; Climate Risk; Social Accounting; Investment; Governance; Safety; Climate Change; Environmental Sustainability; Corporate Social Responsibility and Impact; Financial Services Industry
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      Chatterji, Aaron K., and Michael W. Toffel. "It’s Time to Unbundle ESG." Harvard Business Review (website) (September 20, 2024).
      • August 2024 (Revised August 2024)
      • Background Note

      Note on Adherence in Healthcare

      By: Regina E. Herzlinger, Zachery Page and Ben Creo
      This note provides an overview of adherence in healthcare. It discusses systemwide costs of non-adherence, common barriers to adherence, relevant stakeholders, novel compliance tactics, and the impact on digital therapeutic adoption. It is recommended as a companion to... View Details
      Keywords: Health Care and Treatment; Behavior; Health Industry
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      Herzlinger, Regina E., Zachery Page, and Ben Creo. "Note on Adherence in Healthcare." Harvard Business School Background Note 325-025, August 2024. (Revised August 2024.)
      • August 2024
      • Case

      Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic

      By: Susanna Gallani, Karen L. Sedatole and Sarah Mehta
      Set in March 2024, this case is about CWC Alliance (CWC), a nonprofit working to prevent opioid addiction in the U.S. Founder Cammie Wolf Rice launched CWC in 2018 after her son, Christopher Wolf, died of a heroin overdose. Wolf’s dependence on opioids stemmed from a... View Details
      Keywords: Health Care and Treatment; Innovation and Invention; Jobs and Positions; Nonprofit Organizations; Expansion; Growth and Development Strategy; Service Delivery; Mission and Purpose; Health Industry; United States; Georgia (state, US); Atlanta
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      Gallani, Susanna, Karen L. Sedatole, and Sarah Mehta. "Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic." Harvard Business School Case 125-012, August 2024.
      • July 2024
      • Case

      Living up to Purpose and Performance at Parker Hannifin

      By: Hubert Joly, Alicia Dadlani and Martha Hostetter
      In 2019, Parker Hannifin, one of the world’s largest manufacturers of motion and control technologies, did something unusual for an industrial company: it created a purpose statement. Even though it already had a clear business strategy and longstanding culture of... View Details
      Keywords: Mission and Purpose; Health Pandemics; Leadership; Business or Company Management; Organizational Culture; Business Strategy; Communication Strategy; Manufacturing Industry; Industrial Products Industry; Cleveland; Ohio; United States
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      Joly, Hubert, Alicia Dadlani, and Martha Hostetter. "Living up to Purpose and Performance at Parker Hannifin." Harvard Business School Case 525-015, July 2024.
      • July 2024
      • Article

      Chatbots and Mental Health: Insights into the Safety of Generative AI

      By: Julian De Freitas, Ahmet Kaan Uğuralp, Zeliha Uğuralp and Stefano Puntoni
      Chatbots are now able to engage in sophisticated conversations with consumers. Due to the ‘black box’ nature of the algorithms, it is impossible to predict in advance how these conversations will unfold. Behavioral research provides little insight into potential safety... View Details
      Keywords: Autonomy; Chatbots; New Technology; Brand Crises; Mental Health; Large Language Model; AI and Machine Learning; Behavior; Well-being; Technological Innovation; Ethics
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      De Freitas, Julian, Ahmet Kaan Uğuralp, Zeliha Uğuralp, and Stefano Puntoni. "Chatbots and Mental Health: Insights into the Safety of Generative AI." Journal of Consumer Psychology 34, no. 3 (July 2024): 481–491.
      • July 2024 (Revised July 2024)
      • Case

      Gates Ventures: Making Alzheimer's a Forgotten Past

      By: Satish Tadikonda, William Marks, Shardule Shah and Calvin Marambo
      After a personal journey and interest in Alzheimer's Disease (AD) by Bill Gates, Gates Ventures set out to find the best way to accelerate innovation in the field of AD. In partnership with the Alzheimer's Drug Discovery Foundation, Gates Ventures created the... View Details
      Keywords: Philanthropy and Charitable Giving; Entrepreneurial Finance; Health Disorders; Mission and Purpose
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      Tadikonda, Satish, William Marks, Shardule Shah, and Calvin Marambo. "Gates Ventures: Making Alzheimer's a Forgotten Past." Harvard Business School Case 824-075, July 2024. (Revised July 2024.)
      • July 2024
      • Case

      Replika AI: Alleviating Loneliness (A)

      By: Shikhar Ghosh and Shweta Bagai
      Eugenia Kuyda launched Replika AI in 2017 as an empathetic digital companion to combat loneliness and provide emotional support. The platform surged in popularity during the COVID-19 pandemic, offering non-judgmental support to isolated users. By 2023, Replika boasted... View Details
      Keywords: Entrepreneurship; Ethics; Health Pandemics; AI and Machine Learning; Well-being; Technology Industry
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      Ghosh, Shikhar, and Shweta Bagai. "Replika AI: Alleviating Loneliness (A)." Harvard Business School Case 824-088, July 2024.
      • June 2024
      • Article

      Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes

      By: Peter N. Hadar, Susanna Gallani and Lidia Moura
      Physician burnout, which is prevalent in neurology, has accelerated in recent years. While multifactorial, a major contributing factor to burnout is a payment model that rewards volume over quality, leaving physicians overburdened and unfulfilled. The aim of this... View Details
      Keywords: Compensation and Benefits; Personal Development and Career; Well-being; Motivation and Incentives
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      Hadar, Peter N., Susanna Gallani, and Lidia Moura. "Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes." Neurology: Clinical Practice 14, no. 1 (June 2024).
      • 2024
      • Working Paper

      Health, Human Capital Development and the Longevity of Japanese Elites Since 710

      By: Tom Nicholas and Hiroshi Shimizu
      We examine the lifespan of over 40,000 elites in Japan born between 710 and 1912, including samurai warriors, feudal lords, business, political, cultural, and religious leaders at the apex of the social hierarchy. Japanese elites experienced increases in lifespan about... View Details
      Keywords: Life Expectancy; Status and Position; Health; History; Human Capital; Japan
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      Nicholas, Tom, and Hiroshi Shimizu. "Health, Human Capital Development and the Longevity of Japanese Elites Since 710." Working Paper, June 2024.
      • June 2024
      • Article

      Redistributive Allocation Mechanisms

      By: Mohammad Akbarpour, Piotr Dworczak and Scott Duke Kominers
      Many scarce public resources are allocated at below-market-clearing prices, and sometimes for free. Such "non-market" mechanisms sacrifice some surplus, yet they can potentially improve equity. We develop a model of mechanism design with redistributive concerns. Agents... View Details
      Keywords: Equality and Inequality; Welfare; Mathematical Methods; Market Design; Cost vs Benefits
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      Akbarpour, Mohammad, Piotr Dworczak, and Scott Duke Kominers. "Redistributive Allocation Mechanisms." Journal of Political Economy 132, no. 6 (June 2024): 1831–1875. (Authors' names are in certified random order.)
      • May 2024 (Revised February 2025)
      • Case

      Choosing the Course of Passion: Brooke Boyarsky Pratt at knownwell

      By: Jon M. Jachimowicz and Alexis Lefort
      Brooke Boyarsky Pratt (HBS ’13) enjoyed considerable success in her early career, quickly climbing the ranks to associate partner at McKinsey, and later becoming an executive vice president at Berkadia, a Berkshire Hathaway portfolio company. Throughout these years,... View Details
      Keywords: Passion; Career; Career Planning; Purpose; Personal Development and Career; Mission and Purpose; Identity; Business Startups; Health Care and Treatment; Health Disorders; Growth and Development Strategy; Market Entry and Exit; Health Industry; United States
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      Jachimowicz, Jon M., and Alexis Lefort. "Choosing the Course of Passion: Brooke Boyarsky Pratt at knownwell." Harvard Business School Case 424-040, May 2024. (Revised February 2025.)
      • May 2024
      • Article

      The Health Risks of Generative AI-Based Wellness Apps

      By: Julian De Freitas and G. Cohen
      Artifcial intelligence (AI)-enabled chatbots are increasingly being used to help people manage their mental health. Chatbots for mental health and particularly ‘wellness’ applications currently exist in a regulatory ‘gray area’. Indeed, most generative AI-powered... View Details
      Keywords: AI and Machine Learning; Well-being; Governing Rules, Regulations, and Reforms; Applications and Software
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      De Freitas, Julian, and G. Cohen. "The Health Risks of Generative AI-Based Wellness Apps." Nature Medicine 30, no. 5 (May 2024): 1269–1275.
      • April 29, 2024
      • Editorial

      Stemming the Ripple Effect of Untreated Mental Illness: A Prescription for Change: Reimagining U.S. Healthcare

      By: Lidia Moura and Susanna Gallani
      Keywords: Well-being; Health Care and Treatment; Health Disorders; Change
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      Moura, Lidia, and Susanna Gallani. "Stemming the Ripple Effect of Untreated Mental Illness: A Prescription for Change: Reimagining U.S. Healthcare." Psychology Today (website) (April 29, 2024).
      • April 2024 (Revised July 2024)
      • Case

      Market Dynamics and Moral Dilemmas: Novo Nordisk’s Weight-Loss Drugs

      By: Joseph L. Badaracco, Tom Quinn and John Schultz
      Danish pharmaceutical company Novo Nordisk was owned by a charitable foundation, and since its founding in the 1920s had focused on producing insulin to treat diabetes. In 2017, however, it released Ozempic, a diabetes treatment with the revolutionary side effect of... View Details
      Keywords: Cost vs Benefits; Decisions; Judgments; Values and Beliefs; Global Strategy; Health Care and Treatment; Patents; Growth and Development Strategy; Growth Management; Product Positioning; Supply and Industry; Supply Chain; Corporate Social Responsibility and Impact; Mission and Purpose; Philanthropy and Charitable Giving; Opportunities; Social Issues; Equality and Inequality; Health Industry; Health Industry; Denmark; United States; Europe; China; India; Middle East; North Africa
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      Badaracco, Joseph L., Tom Quinn, and John Schultz. "Market Dynamics and Moral Dilemmas: Novo Nordisk’s Weight-Loss Drugs." Harvard Business School Case 324-114, April 2024. (Revised July 2024.)
      • 2024
      • Working Paper

      The Effects of Medical Debt Relief: Evidence from Two Randomized Experiments

      By: Raymond Kluender, Neale Mahoney, Francis Wong and Wesley Yin
      Two in five Americans have medical debt, nearly half of whom owe at least $2,500. Concerned by this burden, governments and private donors have undertaken large, high-profile efforts to relieve medical debt. We partnered with RIP Medical Debt to conduct two randomized... View Details
      Keywords: Borrowing and Debt; Credit; Outcome or Result; Well-being; Personal Finance
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      Kluender, Raymond, Neale Mahoney, Francis Wong, and Wesley Yin. "The Effects of Medical Debt Relief: Evidence from Two Randomized Experiments." NBER Working Paper Series, No. 32315, April 2024.
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