Publications
Publications
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- All HBS Web
(541)
- Faculty Publications (58)
- December 2014
- Article
The Discipline of Business Experimentation
By: Stefan Thomke and Jim Manzi
The data you already have can't tell you how customers will react to innovations. To discover if a truly novel concept will succeed, you must subject it to a rigorous experiment. In most companies, tests do not adhere to scientific and statistical principles. As a... View Details
- April 2014
- Case
Merrimack Pharmaceuticals, Inc. (A)
By: Amy C. Edmondson, Bethany S. Gerstein and Melissa Valentine
In 2006, Merrimack Pharmaceuticals was a fast-growing biotechnology company. Its leadership team was divided over whether to keep R&D organized in functional departments or transition to interdisciplinary teams. As a small company, Merrimack's R&D organization had... View Details
- July 2013 (Revised November 2021)
- Module Note
Exploration vs. Exploitation
By: Willy Shih
This module note introduces James March's concept of exploration and exploitation, and the management challenge of balancing the allocation of resources to the two activities in the firm. The note also touches on the O'Reilly and Tushman paper on the ambidextrous... View Details
Keywords: Exploration And Exploitation; Exploitation; Research; Scientific Research; Product Commercialization; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Knowledge Acquisition; Growth and Development Strategy; Resource Allocation; Strategic Planning; Research and Development; Science-Based Business; Corporate Strategy; Knowledge Sharing; Biotechnology Industry; Information Technology Industry; Manufacturing Industry; Medical Devices and Supplies Industry; Pharmaceutical Industry; Semiconductor Industry; Technology Industry; United States
- 2014
- Working Paper
Bridging Science and Technology Through Academic-Industry Partnerships
By: Sen Chai and Willy C. Shih
Scientific research and its translation into commercialized technology is a driver of wealth creation and economic growth. Partnerships to foster the translational processes from public research organizations, such as universities and hospitals, to private firms are a... View Details
- April 2012
- Case
Danish National Advanced Technology Foundation
By: Willy Shih and Margaret Pierson
Danish National Advanced Technology Foundation (DNATF), a government agency, invests in public-private partnerships to stimulate commercialization of Danish scientific research within the country's industry. DNATF established a process for evaluating proposals, making... View Details
- July 2011 (Revised January 2013)
- Case
Digital Microscopy Is Making Me Crazy!
By: Willy Shih
For Carl Zeiss Microimaging, modular hardware and software enabled customers to tailor Zeiss's broad range of microscopy systems hardware and software to meet a wide range of needs from basic scientific research in the biological and medical sciences to clinical... View Details
- 2011
- Case
Scientific Glass, Inc.: Inventory Management: Brief Case No. 4208.
By: Steven Wheelwright and William Schmidt
- June 2010 (Revised January 2011)
- Case
Scientific Glass Incorporated: Inventory Management
By: Steven C. Wheelwright and William Schmidt
Scientific Glassware is a fast-growing, privately held company that provides specialized glassware for laboratory and research facilities. Excess inventory is tying up extra capital needed to fund the company's expansion plans. The newly hired Manager of Inventory... View Details
- June 2010 (Revised January 2011)
- Teaching Note
Scientific Glass Incorporated: Inventory Management (Brief Case)
By: Steven C. Wheelwright and William Schmidt
Teaching Note for 4208 View Details
- 2010
- Case
Scientific Glass, Inc.: Inventory Management (TN): Brief Case No. 4209.
By: Steven Wheelwright and William Schmidt
- Article
The Evolution of Science-Based Business: Innovating How We Innovate
By: Gary P. Pisano
Science has long been connected to innovation and to business. As early as the late 19th century, chemical companies, realizing the commercial potential of science, created the first industrial research laboratories. During much of the 20th century, large-scale... View Details
- November 2009 (Revised January 2011)
- Case
International AIDS Vaccine Initiative
By: Allen S. Grossman and Cathy Ross
Dedicated to accelerating the development of a safe, effective, accessible, preventive HIV vaccine, the International AIDS Vaccine Initiative (IAVI) pioneered ways of addressing the inadequate incentive structures that prevented progress toward vaccines for AIDS and... View Details
- July – August 2009
- Article
Restoring American Competitiveness
By: Gary P. Pisano and Willy C. Shih
For decades, U.S. companies have been outsourcing manufacturing in the belief that it held no competitive advantage. That's been a disaster, maintain Harvard professors Pisano and Shih, because today's low-value manufacturing operations hold the seeds of tomorrow's... View Details
- 2009
- Chapter
Entrepreneurship and the History of Globalization
By: G. Jones and R. Daniel Wadhwani
In this article, we build on the recent efforts of scholars to reintroduce entrepreneurship into the research agenda of business historians. We examine the value and limitations of adapting recent social scientific theories and methods on entrepreneurship to research... View Details
- December 2008
- Article
Which Kind of Collaboration Is Right for You?
By: Roberto Verganti and Gary P. Pisano
Nowadays, virtually no companies innovate alone. Firms team up with a variety of partners, in a wide number of ways, to create new technologies, products, and services. But what is the best way to leverage the power of outsiders? To help executives answer that... View Details
- September 2008
- Case
Pfizer Inc: Building an Innovation Center
By: Stefan H. Thomke and Ashok Nimgade
The case describes Pfizer's efforts to build and run an innovation center in Cambridge, Massachusetts. As the center goes through different periods of leadership and strategic models, its relationship with the corporation and other research sites is explored. The case... View Details
- July–August 2008
- Article
Interview with a Quality Leader: Regina E. Herzlinger on Consumer-Driven Healthcare
Regina E. Herzlinger is the Nancy R. McPherson Professor of Business Administration Chair at the Harvard Business School, Cambridge, MA. She received her bachelor's degree from MIT and her doctorate from the Harvard Business School The first woman to be tenured and... View Details
- May 2008 (Revised May 2008)
- Case
Symyx Technologies, Inc.
By: H. Kent Bowen, Courtney Purrington and Thomas D. Perry
Symyx is a science-based company spun out of Berkeley. Its unique materials technology has been exploited for 10 years, but the company needs a new business model. The company concept required the invention of hardware and software to do high throughput materials... View Details
- May 2008 (Revised December 2010)
- Case
Chi Mei Optoelectronics
By: Willy C. Shih, Chintay Shih, Jyun-Cheng Wang and Ho Howard Yu
Chi Mei is a Taiwanese industrial group that makes a major diversification into the technology intensive TFT-LCD flat panel display industry. Because the diversification is far away from its core competence in petrochemicals, it is an opportunity to examine how the... View Details
- May 2008
- Article
When Winning Is Everything
By: Deepak Malhotra, Gillian Ku and J. Keith Murnighan
In the heat of competition, executives can easily become obsessed with beating their rivals. This adrenaline-fueled emotional state, which the authors call competitive arousal, often leads to bad decisions. Managers can minimize the potential for competitive arousal... View Details