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      • Faculty Publications  (417)

      Regina E. HerzlingerRemove Regina E. Herzlinger →

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      • January 2023
      • Case

      Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

      By: Regina Herzlinger and Brian Walker
      What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details
      Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry
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      Herzlinger, Regina, and Brian Walker. "Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery." Harvard Business School Case 323-045, January 2023.
      • December 2022 (Revised September 2024)
      • Case

      Sword Health

      By: Regina E. Herzlinger, Annelena Lobb and Carin-Isabel Knoop
      Virgilio “V” Bento, CEO of Sword Health—a startup that provided virtual physical therapy to patients in self-insured firms via AI and sensor technology with supervision by a physical therapist with a doctorate—considered how to increase its U.S. market share. To do so,... View Details
      Keywords: Business Growth and Maturation; Competitive Strategy; Health Industry; Technology Industry
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      Herzlinger, Regina E., Annelena Lobb, and Carin-Isabel Knoop. "Sword Health." Harvard Business School Case 323-022, December 2022. (Revised September 2024.)
      • November 2022
      • Case

      Ajax Health: A New Model for Medical Technology Innovation

      By: Regina E. Herzlinger and Ben Creo
      This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
      Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Technology Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
      • November 2022
      • Case

      The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales

      By: Regina E. Herzlinger and Tiffany Farrell
      Can an online, direct-to-consumer pharmacy both improve the quality and speed of care for patients who need branded drugs and stabilize profits for pharmaceutical manufacturers? UpScript, after years spent achieving legal and regulatory compliance and simultaneous... View Details
      Keywords: DTC; Internet and the Web; Marketing Channels; Customer Value and Value Chain; Governing Rules, Regulations, and Reforms; Competitive Strategy; Service Delivery; Growth and Development Strategy; Pharmaceutical Industry; Health Industry; Retail Industry
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      Herzlinger, Regina E., and Tiffany Farrell. "The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales." Harvard Business School Case 323-031, November 2022.
      • November 1, 2022
      • Article

      To Prepare for Future Surges, U.S. Hospitals Must Start Planning—& Sharing Resources—Now!

      By: Regina E. Herzlinger
      Keywords: COVID-19; Crisis Management; Health Pandemics; Disruption; Planning; Health Industry; United States
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      Herzlinger, Regina E. "To Prepare for Future Surges, U.S. Hospitals Must Start Planning—& Sharing Resources—Now!" Medical Device News Magazine (November 1, 2022).
      • October 2022 (Revised September 2024)
      • Case

      mPharma: Scaling Access to Affordable Primary Care in Africa

      By: Regina E. Herzlinger and Ben Creo
      mPharma hopes to scale up to create the largest pan-African healthcare company ever to provide much-needed primary care in retail pharmacies; a reliable, fairly priced supply of drugs; and micro-insurance for drugs. They must prioritize launching a telemedicine... View Details
      Keywords: Africa; Pharmaceutical Companies; Pharmacy Benefit Manager; Health Care; Health Care And Treatment; Health Care Costs; Health Care Delivery; Health Care Entrepreneurship; Telehealth; Health Equity; Corporate Strategy; Social Entrepreneurship; Equity; Growth and Development Strategy; Expansion; Product Launch; Customer Value and Value Chain; Social Enterprise; Multinational Firms and Management; Pharmaceutical Industry; Health Industry; Africa
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      Herzlinger, Regina E., and Ben Creo. "mPharma: Scaling Access to Affordable Primary Care in Africa." Harvard Business School Case 323-033, October 2022. (Revised September 2024.)
      • 29 Sep 2022
      • Talk

      Lessons from U.S. COVID Hospital Crisis

      By: Regina E. Herzlinger
      Keywords: COVID-19 Pandemic; Hospital Capacity; Health Care and Treatment; Health Pandemics; Health Industry; United States
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      Herzlinger, Regina E. "Lessons from U.S. COVID Hospital Crisis." Henry Stewart Talks Ltd., September 29, 2022.
      • July 1, 2022
      • Editorial

      New Transparency Rule Helps Rein in Health Care Costs

      By: Regina E. Herzlinger and Cynthia A. Fisher
      Over the last year, consumer prices have grown 60% faster than wages. Employers can help their employees contend with this high inflation by addressing a long-running source: health care costs. View Details
      Keywords: Healthcare Costs; Consumer Prices; Inflation and Deflation; Wages; Health Industry
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      Herzlinger, Regina E., and Cynthia A. Fisher. "New Transparency Rule Helps Rein in Health Care Costs." Boston Herald (July 1, 2022).
      • May 2022
      • Other Article

      The Children of Ukraine Are Our Hope for the Future

      By: Regina E. Herzlinger
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      Herzlinger, Regina E. "The Children of Ukraine Are Our Hope for the Future." Medium (May 2, 2022).
      • March 5, 2022
      • Article

      Hospital Capacity Shortages: An SEC-Backed Transparency “PULL” Will Open Beds Faster Than a “PUSH” by HHS

      By: Regina E. Herzlinger
      In the new normal of ongoing pandemics, hospital bed shortages will continue. Healthcare innovation expert and author of the upcoming book Innovating in Healthcare: Creating Breakthrough Services, Products, and Business Models (Wiley, 2023, 978-1119543008), HBS... View Details
      Keywords: Hospital Capacity; Access To Care; Health Pandemics; Health Care and Treatment; Performance Capacity; Planning
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      Herzlinger, Regina E. "Hospital Capacity Shortages: An SEC-Backed Transparency “PULL” Will Open Beds Faster Than a “PUSH” by HHS." Healthcare Business Today (March 5, 2022).
      • February 24, 2022
      • Article

      Want to Prevent the Next Hospital Bed Crisis? Enlist the SEC

      By: Regina E. Herzlinger and Richard Boxer
      During the initial phases of the COVID-19 pandemic, many U.S. hospitals could not provide enough beds to meet demand. Solving the problem of inadequate capacity is of utmost importance in the “new normal,” which requires recognizing the ongoing need for hospital-based... View Details
      Keywords: COVID; COVID-19 Pandemic; Hospital Capacity; SEC Regulation; Health Pandemics; Crisis Management; Performance Capacity; Planning
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      Herzlinger, Regina E., and Richard Boxer. "Want to Prevent the Next Hospital Bed Crisis? Enlist the SEC." Harvard Business School Working Knowledge (February 24, 2022).
      • February 18, 2022
      • Article

      Transparency as a Solution for COVID-19 Related Hospital Capacity Issues

      By: Regina E. Herzlinger and Richard Boxer
      In the initial phases of the COVID-19 pandemic, many U.S. hospitals could not provide an adequate supply of beds to meet demand. Solving the problem of hospital bed capacity is of great importance in the “new normal,” which requires recognizing that SARS-CoV-2 is but... View Details
      Keywords: COVID; COVID-19 Pandemic; Health Care; Health Care Demand; Health Care Delivery; Health Care Industry; Health Care Operations; Health Care Policy; Transparency; Hospital; Hospital Management; Hospitals; Health Pandemics; Health Care and Treatment; Service Delivery; Operations; Performance Capacity; Policy; Health Industry
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      Herzlinger, Regina E., and Richard Boxer. "Transparency as a Solution for COVID-19 Related Hospital Capacity Issues." Health Affairs Forefront (February 18, 2022).
      • 2 Dec 2021
      • Interview

      How To Make Healthcare Innovation Happen

      By: Regina E. Herzlinger
      Regina Herzlinger has been called “the godmother of consumer-driven healthcare” because of her groundbreaking scholarly articles and books on the subject. As a professor of business administration at Harvard Business School for nearly 50 years, her focus has supported... View Details
      Keywords: Health Care and Treatment; Innovation and Invention
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      Herzlinger, Regina E. "How To Make Healthcare Innovation Happen." Raise the Line (podcast), Osmosis, December 2, 2021.
      • Article

      Transparency as a Solution for the Hospital Capacity Problem

      By: Regina E. Herzlinger
      COVID dramatically clarified a shortcoming in our great healthcare system, but like everything in the world, it has its shortcomings. What we see through the apex of COVID is that many hospitals in hotspot areas cannot provide an adequate supply of beds. Although the... View Details
      Keywords: Hospital Capacity; Health Care and Treatment; Performance Capacity; Planning; Cooperation
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      Herzlinger, Regina E. "Transparency as a Solution for the Hospital Capacity Problem." Ohio State Law Journal 82, no. 5 (December 2021): 787–794.
      • 2021
      • White Paper

      Go Out and Innovate! Perspectives on Educating Health Care Leadership in the Time of Innovation

      By: Regina E. Herzlinger, Anthony Stanowski, Edward Schumacher, Eugene Schneller, Kaveh Safavi, Quint Studer, Andrew Jay, Tom Robinson and Kevin Mahoney
      The CAHME Innovation Council unanimously believes that education is essential. In evaluating the competency domain of management and leadership, and learning from programs that prioritize innovation, we ask how do we develop competencies in future leaders to succeed in... View Details
      Keywords: Health Care; Health Care Industry; Health Care Entrepreneurship; Innovation; Innovation & Entrepreneurship; Health Industry
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      Herzlinger, Regina E., Anthony Stanowski, Edward Schumacher, Eugene Schneller, Kaveh Safavi, Quint Studer, Andrew Jay, Tom Robinson, and Kevin Mahoney. "Go Out and Innovate! Perspectives on Educating Health Care Leadership in the Time of Innovation." White Paper, Commission on Accreditation of Healthcare Management Education (CAHME), November 2021.
      • June 15, 2021
      • Article

      Cutting the Gordian Knot of Employee Health Care Benefits and Costs: A Corporate Model Built on Employee Choice

      By: Regina E. Herzlinger and Barak D. Richman
      President Joe Biden’s promise to give every American access to affordable health insurance is well-intentioned, but his plan’s policy elements—a public option, a permanent expanded tax credit—require congressional approval and would expend significant political and... View Details
      Keywords: Health Insurance; Health Insurance Marketplaces; Health Care Delivery; Health Care Financing; Health Care Industry; Health Care and Treatment; Insurance; Service Delivery; Cost Management; Health Industry; United States
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      Herzlinger, Regina E., and Barak D. Richman. "Cutting the Gordian Knot of Employee Health Care Benefits and Costs: A Corporate Model Built on Employee Choice." Health Affairs Blog (June 15, 2021).
      • June 10, 2021
      • Article

      Preparing Hospitals for the Next Pandemic

      By: Regina E. Herzlinger and Barak D. Richman
      The COVID-19 epidemic response has shown that the U.S. is blessed with heroic physicians and other health care providers, researchers, and facilities. But it has also revealed a health care system that was woefully unprepared for the surge of pandemic patients. In the... View Details
      Keywords: Hospital; Hospital Management; Hospitals—administration; Health Care; Health Care Industry; Health Care Investment; Health Care Operations; Health Pandemics; Health Care and Treatment; Operations; Performance Improvement; Investment; Health Industry; United States
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      Herzlinger, Regina E., and Barak D. Richman. "Preparing Hospitals for the Next Pandemic." Harvard Business Review Digital Articles (June 10, 2021).
      • Article

      Ten Year Sunset Rule for Healthcare Regulation Is a Nonstarter and Discouragement to Post-COVID-19 Investment

      By: Regina E. Herzlinger and Eugene Schneller
      U.S. healthcare delivery has not benefitted from the same productivity growth as many other service industries, such as bricks and mortar retailing, a loss that has gravely diminished cost control and access. Regulatory capture, which creates barriers to venture... View Details
      Keywords: Health Care; COVID-19; Regulation; Health Care and Treatment; Health Pandemics; Governing Rules, Regulations, and Reforms; Investment
      Citation
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      Herzlinger, Regina E., and Eugene Schneller. "Ten Year Sunset Rule for Healthcare Regulation Is a Nonstarter and Discouragement to Post-COVID-19 Investment." Journal of Health Care Finance 47, no. 4 (Spring 2021). (Special Commentary.)
      • March 2021 (Revised January 2022)
      • Case

      Philips: Redefining Telehealth

      By: Regina E. Herzlinger, Alec Petersen, Natalie Kindred and Sara M. McKinley
      As one of the world’s largest healthcare companies, Philips sought to reach beyond the walls of the hospital and expand its hospital-to-home program to gain future competitive advantage through technology solutions combining predictive analytics with care delivery. By... View Details
      Keywords: Health Care; Philips; Visicu; Telemedicine; eICU; Accountable Care Organization; ACO; Bundled Payment; Hospital To Home; Patient Monitoring Devices; Home Health Care; Health Care and Treatment; Communication Technology; Quality; Safety; Performance Productivity; Performance Capacity; Performance Efficiency; Consumer Behavior; Emerging Markets; Health Industry; Telecommunications Industry; Netherlands
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      Herzlinger, Regina E., Alec Petersen, Natalie Kindred, and Sara M. McKinley. "Philips: Redefining Telehealth." Harvard Business School Case 321-135, March 2021. (Revised January 2022.) (As companion reading for this case, see: Regina E. Herzlinger and Charles Huang. "Note on Bundled Payment in Health Care," HBS Background Note 312-032.)
      • March 2021
      • Case

      Humana (A)

      By: Regina E. Herzlinger and Ashley Ifeadike
      To implement a bold new strategy, Humana needed to decide how to prioritize the pillars; where to own and where to partner; how much risk is acceptable; and how to continue to deliver strong operational performance while implementing a new strategy. Had the firm made... View Details
      Keywords: Health & Wellness; Health Care Industry; Health Care Costs; Health Insurance; Health Insurance Marketplaces; Health Care and Treatment; Cost; Insurance; Strategy; Health Industry; United States
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      Herzlinger, Regina E., and Ashley Ifeadike. "Humana (A)." Harvard Business School Case 321-097, March 2021.
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