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      • November 2023
      • Supplement

      'Care in Every Drop': Ayala Corporation and Manila Water (B)

      By: Debora L. Spar, Paul Healy, Tricia Peralta and Julia Comeau
      Since 1834, eight generations of the Ayala family have used their conglomerate to fund nation-building projects in the Philippines, including investments in tramcars, telecommunications, hospitals, and schools. In 1997, Ayala’s subsidiary, Manila Water, took control of... View Details
      Keywords: Family Business; Economic Growth; Social Entrepreneurship; Climate Change; Natural Resources; Crisis Management; Failure; Privatization; Social Issues; Urban Development; Adaptation; Infrastructure; Utilities Industry; Philippines
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      Spar, Debora L., Paul Healy, Tricia Peralta, and Julia Comeau. "'Care in Every Drop': Ayala Corporation and Manila Water (B)." Harvard Business School Supplement 324-039, November 2023.
      • November 2023 (Revised April 2024)
      • Case

      BiomX: Bringing Phage Back to the Stage

      By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
      In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
      Keywords: Working Capital; Financing and Loans; Health Testing and Trials; Product Development; Research and Development; Science-Based Business; Commercialization; Biotechnology Industry; Pharmaceutical Industry
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      Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
      • 2023
      • Working Paper

      Coordinated R&D Programs and the Creation of New Industries

      By: Daniel P. Gross and Maria P. Roche
      Complex systems technologies—including “deep tech”—are prone to numerous frictions that stymie commercial development. Yet technologies with these features underpin some of the most valuable industries of the past century. We examine how large, mission-oriented... View Details
      Keywords: Research and Development; Policy; Business and Government Relations; Technological Innovation; Collaborative Innovation and Invention
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      Gross, Daniel P., and Maria P. Roche. "Coordinated R&D Programs and the Creation of New Industries." Harvard Business School Working Paper, No. 24-027, April 2023. (Revised October 2024.)
      • November 2023 (Revised May 2024)
      • Case

      Kickstarter: Crowdfunding for the Arts

      By: Rohit Deshpandé and Alexis Lefort
      Kickstarter was a virtual crowdfunding platform and community that allowed creators of all kinds to raise funding for creative projects. The executive team was wrestling with a tension in its business model: the organization earned the majority of its revenue from... View Details
      Keywords: Fundraising; Mission; Crowdfunding; Corporate Social Responsibility and Impact; Mission and Purpose; Philanthropy and Charitable Giving; Arts; Web Services Industry; United States
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      Deshpandé, Rohit, and Alexis Lefort. "Kickstarter: Crowdfunding for the Arts." Harvard Business School Case 524-016, November 2023. (Revised May 2024.)
      • October 2023 (Revised November 2023)
      • Teaching Note

      The Miccosukee Tribe and the Battle to Save the Everglades: A Miami Climate Action Story

      By: Rosabeth Moss Kanter and Jacob A. Small
      Teaching Note for HBS Case No. 324-002. "Miccosukee" explores the challenges of coordinating actions to solve a complex systems problem—from individuals, small organizations, and coalitions of multiple organizations. The case discusses the impact of climate change and... View Details
      Keywords: Climate Change; Leading Change; Natural Environment; Florida; Everglades National Park
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      Kanter, Rosabeth Moss, and Jacob A. Small. "The Miccosukee Tribe and the Battle to Save the Everglades: A Miami Climate Action Story." Harvard Business School Teaching Note 324-048, October 2023. (Revised November 2023.)
      • September 2023 (Revised September 2023)
      • Teaching Note

      Roche: Innovation and Access to Healthcare

      By: George Serafeim
      Teaching Note for HBS Case No. 123-075. In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to... View Details
      Keywords: ESG; Access To Care; Healthcare; Healthcare Access; Innovation; Social Impact; Affordable; Health Care and Treatment; Innovation and Invention; Product Development; Resource Allocation; Corporate Social Responsibility and Impact; Health Industry
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      Serafeim, George. "Roche: Innovation and Access to Healthcare." Harvard Business School Teaching Note 124-028, September 2023. (Revised September 2023.)
      • September 2023
      • Article

      Addressing Vaccine Hesitancy: Experimental Evidence from Nine Countries during the COVID-19 Pandemic

      By: Vincenzo Galasso, Vincent Pons, Paola Profeta, Martin McKee, David Stuckler, Michael Becher, Sylvain Brouard and Martial Foucault
      We study the impact of public health messages on intentions to vaccinate and vaccination uptakes, especially among hesitant groups. We performed an experiment comparing the effects of egoistic and altruistic messages on COVID-19 vaccine intentions and behaviour. We... View Details
      Keywords: COVID-19; Vaccination; Vaccine Hesitancy; Information Campaigns; Health Pandemics; Behavior; Information
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      Galasso, Vincenzo, Vincent Pons, Paola Profeta, Martin McKee, David Stuckler, Michael Becher, Sylvain Brouard, and Martial Foucault. "Addressing Vaccine Hesitancy: Experimental Evidence from Nine Countries during the COVID-19 Pandemic." BMJ Global Health 8, no. 9 (September 2023).
      • Article

      Update on E-liability Accounting

      By: Robert Kaplan, Karthik Ramanna and Piyush Jha
      Since publication of the original E-liability carbon accounting paper (HBR, Nov 2021), we created the E-liability Institute to help companies, governments, and nonprofits implement the method. The Institute’s mission is to test and validate the method, and develop... View Details
      Keywords: Decarbonization; Carbon Footprint; Supply Chain; Environmental Sustainability; Environmental Accounting
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      Kaplan, Robert, Karthik Ramanna, and Piyush Jha. "Update on E-liability Accounting." Accountability in a Sustainable World Quarterly, no. 4 (September 2023): 96–117.
      • July 2023
      • Case

      Moderna: Everything, Everywhere, All at Once

      By: Satish Tadikonda, Shikhar Ghosh and William Marks
      Coming out of the COVID-19 pandemic, Moderna was riding the successes of developing a vaccine in record time and helping stem the tide of the crisis. However, the company had grown at an incredible rate, more than doubled its number of employees, and had to put on hold... View Details
      Keywords: Health Pandemics; Selection and Staffing; Growth Management; Management Succession; Retirement; Technological Innovation; Corporate Strategy; Biotechnology Industry
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      Tadikonda, Satish, Shikhar Ghosh, and William Marks. "Moderna: Everything, Everywhere, All at Once." Harvard Business School Case 824-021, July 2023.
      • 3 Jun 2023
      • Talk

      Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen

      By: Regina E. Herzlinger
      The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
      Keywords: Policy; Health Pandemics; Health Care and Treatment; Innovation and Invention; Health Industry; Health Industry
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      Herzlinger, Regina E. "Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen." Harvard Business School Alumni Reunion, Boston, MA, June 3, 2023. (Link to cases described in this talk.)
      • June 2023
      • Article

      The Effect of Firms' Information Exposure on Safeguarding Employee Health: Evidence from COVID-19

      By: Lisa Yao Liu and Shirley Lu
      We show that information exposure through international business networks enables firms to take proactive measures that benefit employees and potentially the local community. Specifically, in the early days of COVID-19, firms that have business networks with China and... View Details
      Keywords: COVID-19 Pandemic; Networks; Knowledge Use and Leverage; Health Pandemics; Decision Choices and Conditions; Corporate Social Responsibility and Impact
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      Liu, Lisa Yao, and Shirley Lu. "The Effect of Firms' Information Exposure on Safeguarding Employee Health: Evidence from COVID-19." Journal of Accounting Research 61, no. 3 (June 2023): 891–933.
      • June 2023
      • Case

      Verve Therapeutics: Taking DNA Editing to Heart

      By: Shikhar Ghosh and Shweta Bagai
      Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
      Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
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      Ghosh, Shikhar, and Shweta Bagai. "Verve Therapeutics: Taking DNA Editing to Heart." Harvard Business School Case 823-113, June 2023.
      • May 2023
      • Article

      A Public Health Approach to Negative News Media: The 3-to-1 Solution

      By: Tyler VanderWeele and Arthur C. Brooks
      There is clear evidence that the prevalence of negative media reporting has increased substantially over the past years. There is evidence also that this negative reporting adversely affects social interactions, as well as health and well-being outcomes. Given the wide... View Details
      Keywords: News; Social Networks; Contagion; Population Health; Media; Health; Welfare; Organizational Change and Adaptation; Journalism and News Industry
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      VanderWeele, Tyler, and Arthur C. Brooks. "A Public Health Approach to Negative News Media: The 3-to-1 Solution." American Journal of Health Promotion 37, no. 4 (May 2023): 447–449.
      • May–June 2023
      • Article

      Unmasking Behaviors During the Pandemic with Video Analytics

      By: Shunyuan Zhang, Kaiquan Xu and Kannan Srinivasan
      In 2020, as the novel coronavirus spread globally, face masks were recommended in public settings to protect against and slow down viral transmission. People complied to varying extents, and their reactions may have been driven by a variety of psychological factors.... View Details
      Keywords: COVID-19 Pandemic; Social Influence; Social Norms; Health Pandemics; Behavior
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      Zhang, Shunyuan, Kaiquan Xu, and Kannan Srinivasan. "Unmasking Behaviors During the Pandemic with Video Analytics." Marketing Science 42, no. 3 (May–June 2023): 440–450.
      • April 2023 (Revised January 2024)
      • Background Note

      Note on Healthcare in Ghana

      By: Regina E. Herzlinger and Ben Creo
      This note provides an overview of the healthcare system in Ghana. It discusses the public and private sector as well as traditional medical practice. It also discusses the country’s pharmaceutical industry. It is recommended as a companion to Professor Regina... View Details
      Keywords: Africa; Pharmaceutical Companies; Pharmacy Benefit Manager; Health Care; Health Care Costs; Health Care Delivery; Health Care Entrepreneurship; Telehealth; Health Equity; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Business and Government Relations; Health Industry; Health Industry; Ghana
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      Herzlinger, Regina E., and Ben Creo. "Note on Healthcare in Ghana." Harvard Business School Background Note 323-112, April 2023. (Revised January 2024.)
      • May 4, 2023
      • Article

      Falling Insulin Prices—What Just Happened?

      By: Leemore S. Dafny
      Recently, more than 100 years after insulin was developed, manufacturers announced price reductions for insulin products. Pressure to reduce prices had long been building, so why would they act now? View Details
      Keywords: Price; Health Care and Treatment; Public Opinion; Demand and Consumers; Pharmaceutical Industry
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      Dafny, Leemore S. "Falling Insulin Prices—What Just Happened?" New England Journal of Medicine 388, no. 18 (May 4, 2023): 1636–1639.
      • April 2023 (Revised July 2023)
      • Case

      Fermenting Accounting Problems at Vermont Kombucha Corp.

      By: Tatiana Sandino and Marshal Herrmann
      Founded in 2005, Vermont Kombucha Corp. (V-Ko) was an early mover in the fledgling U.S. market for kombucha, a drink brewed for its health benefits. Early on, the company captured more than 90% of market share. Under the leadership of its founder and CEO, Joe Williams,... View Details
      Keywords: Going Public; Business Model; Financial Reporting; Ethics; Corporate Governance; Stock Shares; Food and Beverage Industry
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      Sandino, Tatiana, and Marshal Herrmann. "Fermenting Accounting Problems at Vermont Kombucha Corp." Harvard Business School Case 123-064, April 2023. (Revised July 2023.)
      • April 5, 2023
      • Article

      We Need an Operation Warp Speed for Long COVID

      By: Esther K. Choo and Scott Duke Kominers
      With millions of people affected and at least $1 trillion of economic value at stake, long COVID is our next national health emergency. View Details
      Keywords: COVID; COVID-19; COVID-19 Pandemic; Scientific Research; Policy; Health Policy; Innovation; Science; Public Finance; Public Health; Health Disorders; Health Care and Treatment; Human Capital
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      Choo, Esther K., and Scott Duke Kominers. "We Need an Operation Warp Speed for Long COVID." Scientific American (website) (April 5, 2023).
      • March 2023
      • Case

      Between Two Minds: The Staglin Family

      By: Lauren Cohen, Ronnie Stangler and Grace Headinger
      Garen Staglin, Founder and Chairman of One Mind, reflected on his life’s work in brain health. As he contemplated stepping down in the next few years, he weighed how to pass along this legacy to his son, Brandon Staglin, the impetus behind and next generation of the... View Details
      Keywords: Nonprofit Organizations; Well-being; Management Succession; Family Ownership; Mission and Purpose; Health Industry
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      Cohen, Lauren, Ronnie Stangler, and Grace Headinger. "Between Two Minds: The Staglin Family." Harvard Business School Case 223-053, March 2023.
      • March 2023 (Revised March 2023)
      • Case

      Roche: Innovation and Access to Healthcare

      By: George Serafeim, Susanna Gallani and Benjamin Maletta
      In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that had... View Details
      Keywords: ESG (Environmental, Social, Governance) Performance; Sustainable Finance; Growth Strategy And Execution; Sustainability Targets; Impact Evaluation; Healthcare Access; Healthcare Innovation; Healthcare Systems; Healthcare Operations; Finance; Strategy; Health Testing and Trials; Health Care and Treatment; Growth Management; Measurement and Metrics; Innovation Strategy; Corporate Social Responsibility and Impact; Health Industry; Health Industry; Switzerland; North America; Europe; Asia; Latin America; Africa
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      Serafeim, George, Susanna Gallani, and Benjamin Maletta. "Roche: Innovation and Access to Healthcare." Harvard Business School Case 123-075, March 2023. (Revised March 2023.)
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