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  • 21 Apr 2014
  • Research & Ideas

Bio-Piracy: When Western Firms Usurp Eastern Medicine

emerging market entities as imitators. (Cases of bio-piracy indicate the opposite.) From a practical perspective, they wanted to suss out factors that might thwart bio-piracy altogether. In a series of new papers, the researchers trace a... View Details
Keywords: by Carmen Nobel; Legal Services; Biotechnology
  • 10 Sep 2020
  • Blog Post

Founding a Company at the Intersection of Medicine and Technology

surgical robotics to treat lung cancer, the intersection of medicine and technology was a deep interest of his prior to HBS. He is now the Founder and CEO of Alife Health, which uses machine learning to help assess the healthiest embryo... View Details
  • 13 Apr 2017
  • News

What Precision Medicine Can Learn from the NFL

  • 12 Apr 2022
  • Blog Post

The Many Languages of Medicine to Impact Care Delivery

Ted Obi (MS/MBA 2023) is a current MBA student at HBS and a third year medical student at the Icahn School of Medicine at Mount Sinai. His previous experiences include co-founding Melanin Doc, a non-profit supporting the next generation... View Details
  • October 2010 (Revised November 2010)
  • Background Note

Plavix: Drugs in the Age of Personalized Medicine

By: Richard G. Hamermesh, Mara G. Aspinall and Rachel Gordon
PIavix, one of the world's best selling drugs in 2010, appears to have a limited future. Its patent was due to expire soon, and recently new data had been discovered that indicated that a small subset of the population would be at risk for stroke, heart attack, or even... View Details
Keywords: Health Care and Treatment; Product Positioning; Business and Government Relations; Genetics; Competitive Strategy; Pharmaceutical Industry
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  • Web

Kraft Precision Medicine Accelerator - Health Care

Faculty & Research Kraft Precision Medicine Accelerator About the Kraft Precision Medicine Accelerator From 2015–2020, the Harvard Business School Kraft Precision Medicine... View Details
  • 12 Nov 2018
  • News

Precision Medicine Has Transformed Cancer Treatment. Here’s How to Move It Beyond Oncology

  • 01 Mar 2017
  • News

How Deep Brain Stimulation Could Change Medicine

engineers to tweak preexisting medical instruments or develop entirely new medical devices. The general deep brain stimulation procedure is now established practice: For over a decade, neurosurgeons have placed electrodes in the brains of... View Details
Keywords: Janelle Nanos
  • 01 May 2020
  • News

The Business of Medicine in the Era of COVID-19

  • June 2023
  • Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai
Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
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  • December 2022
  • Article

The Contribution of Price Growth to Pharmaceutical Revenue Growth in the United States: Evidence from Medicines Sold in Retail Pharmacies

By: Pragya Kakani, Michael Chernew and Amitabh Chandra
Context: To what extent does pharmaceutical revenue growth depend on new medicines versus increasing prices for existing medicines? Moreover, does using list prices, as is commonly done, instead of prices net of confidential rebates offered by manufacturers, which are... View Details
Keywords: Revenue; Price; Policy; Business Strategy; Pharmaceutical Industry
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  • Working Paper

Rebates in the Pharmaceutical Industry: Evidence from Medicines Sold in Retail Pharmacies in the U.S.

By: Pragya Kakani, Michael Chernew and Amitabh Chandra
Rising list prices are often used to illustrate the burden of prescription drug spending, but payers routinely negotiate rebates from manufacturers that generate differences between list and net prices. List prices are easily available and affect patient cost-sharing,... View Details
Keywords: Pharmaceuticals; Rebates; Health Care and Treatment; Markets; Price; Analysis; Pharmaceutical Industry
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  • Article

One Obstacle to Curing Cancer: Patient Data Isn't Shared

By: Richard G. Hamermesh and Kathy Giusti
Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details
Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States
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  • 11 Apr 2017
  • First Look

First Look at New Research, April 11

treated with unproductive therapies while more easily uncovering therapeutic signals. However, such research initiatives alone will not deliver new medicines to patients in the absence of strong incentives... View Details
  • 14 Jul 2020
  • News

A New Playbook for Cure-Seeking Nonprofits

  • Article

Cybersecurity Features of Digital Medical Devices: An Analysis of FDA Product Summaries

By: Ariel Dora Stern, William J. Gordon, Adam B. Landman and Daniel B. Kramer
Objectives:
To more clearly define the landscape of digital medical devices subject to U.S. Food and Drug Administration (FDA) oversight, this analysis leverages publicly available regulatory documents to characterise the prevalence and trends of software and... View Details
Keywords: Digital; Medicine; FDA; Health Care and Treatment; Applications and Software; Safety; Cybersecurity; Medical Devices and Supplies Industry
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  • June 2024
  • Article

Valuing the Societal Impact of Medicines and Other Health Technologies: A User Guide to Current Best Practices

By: Jason Shafrin, Jaehong Kim, Joshua T. Cohen, Louis P. Garrison, Dana A. Goldman, Jalpa A. Doshi, Joshua Krieger, Darius N. Lakdawalla, Peter J. Neumann, Charles E. Phelps, Melanie D. Whittington and Richard Willke
This study argues that value assessment conducted from a societal perspective should rely on the Generalized Cost-Effectiveness Analysis (GCEA) framework proposed herein. Recently developed value assessment inventories—such as the Second Panel on Cost-Effectiveness’s... View Details
Keywords: Health Care and Treatment; Valuation; Cost vs Benefits; Society
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  • 01 Mar 2012
  • News

Capitalism’s New Agenda

hundreds of millions of rural poor into the market system (as China Mobile did by bringing mobile phone service to the Chinese countryside), that brought medicine where it had been unaffordable (which the Indian pharmaceutical firm Cipla... View Details
Keywords: Joseph L. Bower, Herman B. Leonard, and Lynn S. Paine; social activism; Occupy Wallstreet; Corporate Services; Finance
  • 19 Dec 2017
  • First Look

New Research and Ideas, December 19, 2017

Abstract—No abstract available. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=53633 Characterizing the Drug Development Pipeline for Precision Medicines By: Chandra, Amitabh, Craig Garthwaite, and Ariel Dora Stern... View Details
Keywords: Carmen Nobel
  • 25 Feb 2019
  • News

Impact investing: a new way to fund cures for cancer