Publications

February 1996 (Revised April 1997)
Case

Partners HealthCare System, Inc. (A)

By: Gary P. Pisano and Maryam Golnaraghi

Focuses on the decision confronting senior administrators at the Brigham and Women's Hospital: whether to enter into an affiliation with the Massachusetts General Hospital. Requires students to analyze the complex institutional changes in the health environment and to... View Details

Keywords: Consolidation; Health Care and Treatment; Mergers and Acquisitions; Organizational Change and Adaptation; Change Management; Management Teams; Health Industry; Massachusetts

December 2023 (Revised February 2024)
Case

Transforming Healthcare Delivery at Karolinska University Hospital

By: Susanna Gallani, Mary Witkowski, Elena Corsi and Nikolina Jonsson

The case study examines the journey toward value-based healthcare at Karolinska University Hospital. The hospital's ambitious shift to a patient-centered care delivery model, accompanied by the construction of a new facility, encountered challenges such as high costs,... View Details

Keywords: Change Management; Transformation; Transition; Business Organization; Communication Strategy; Information Infrastructure; Service Delivery; Organizational Change and Adaptation; Organizational Structure; Health Industry; Sweden; Europe

October 2012 (Revised March 2022)
Case

Kleiner-Perkins and Genentech: When Venture Capital Met Science

By: Felda Hardymon and Tom Nicholas

Genentech is a rare success story in the biotechnology industry. Hundreds of billions of dollars of venture capital have been invested without the expected transformational effects. Established in 1976, Genentech was to develop the new science of recombinant DNA into... View Details

Keywords: Innovation ＆ Entrepreneurship; Venture Capital; Innovation and Invention; Entrepreneurship; Information Technology; Science; Biotechnology Industry; United States

March 2014 (Revised September 2017)
Case

salaUno: Eliminating Needless Blindness in Mexico

By: Richard Hamermesh, Regina Garcia Cueller and Valeria Moy

In May 2013 the co-founders and co-CEOs of salaUno, Javier Okhuysen and Carlos Orellana, were encouraged by the results of their fledgling start-up. salaUno was founded as a for-profit enterprise in order to have the capital needed for rapid growth and to fulfill its... View Details

Keywords: Medical Services; Developing Countries; Developing Markets; Health Care Industry; Health Services; Healthcare Ventures; Healthcare Startups; Health Care and Treatment; Health; Business Startups; Developing Countries and Economies; Growth and Development Strategy; Health Industry; Mexico; Mexico City

January 2017
Supplement

Intrapreneurship at DaVita HealthCare Partners: Cash Flow Tool

By: Joseph B. Fuller and Christopher Payton

DaVita Healthcare Partners Inc. (DaVita) is one of the U.S.'s leading dialysis providers, a process whereby persons with end-stage renal disease (ESRD) are connected to a machine that performs the functions of a healthy kidney. Kent Thiry, DaVita's CEO, has expanded... View Details

Keywords: Intrapreneurship; Entrepreneurial Organizations; Startup Management; Startup; Strategic Positioning; Corporate Entrepreneurship; Corporate Strategy; Business Startups; Strategic Planning; Competitive Strategy; Health Industry; United States

August 2013
Course Overview Note

Building Life Science Businesses Fall 2013: Course Outline and Syllabus

By: Richard G. Hamermesh

This Course Outline and Syllabus gives an overview of the Fall 2013 class Building Life Science Businesses. View Details

Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Health Industry; Biotechnology Industry; Medical Devices and Supplies Industry; Asia; North America; Europe

July 2014 (Revised January 2017)
Course Overview Note

Building Life Science Businesses Spring Term 2017: Course Outline and Syllabus

By: Richard G. Hamermesh

This Course Outline and Syllabus gives an overview of the Spring 2016 class Building Life Science Businesses.7 View Details

Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Health Industry; Biotechnology Industry; Medical Devices and Supplies Industry; Asia; North America; Europe

10 Dec 2024
Interview

A New Model for Funding Healthcare Innovation

By: Regina E. Herzlinger and Duke Rohlen

Ajax Health founder Duke Rohlen (HBS MBA 2001) and HBS Professor Regina Herzlinger join host Brian Kenny to discuss the key success factors for both start-up and established medical technology firms. The case “Ajax Health: A New Model for Medical Technology Innovation”... View Details

Keywords: Entrepreneurship; Innovation and Invention; Business Model; Private Equity; Health Industry

December 2005 (Revised October 2013)
Case

Fred Khosravi and AccessClosure (A)

By: Richard Hamermesh and Liz Kind

Fred Khosravi is a serial medical device entrepreneur. In his latest venture, he must decide whether to sell now or continue to develop his current product and whether to market it, sell the company, or IPO. View Details

Keywords: Negotiation; Medical Devices; Venture Capital; Life Sciences; Health Care Industry; Healthcare Technology; Healthcare Ventures; Business Startups; Decision Choices and Conditions; Entrepreneurship; Growth and Development Strategy; Medical Devices and Supplies Industry; United States

September 2012 (Revised September 2012)
Course Overview Note

Building Life Science Businesses Fall 2012: Course Outline and Syllabus

By: Richard G. Hamermesh and Richard G. Hamermesh

This Course Outline and Syllabus gives an overview of the Fall 2012 class Building Life Science Businesses View Details

Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Health Industry; Biotechnology Industry; Medical Devices and Supplies Industry; Asia; North America; Europe

January 2020
Teaching Note

GeBBS Healthcare Solutions: Did You Ever Have to Make Up Your Mind? (A) and (B)

By: Shai Benjamin Bernstein

This teaching note is meant to accompany “GeBBS Healthcare Solutions: Did You Ever Have to Make Up Your Mind? (A),” HBS No. 820-041, and “GeBBS Healthcare Solutions: Did You Ever Have to Make Up Your Mind? (B),” HBS No. 820-074. The cases follow Nitin Thakor, President... View Details

Keywords: Health Care and Treatment; Acquisition; Decision Making; Health Industry

April 1996 (Revised June 2001)
Case

Partners HealthCare System, Inc. (B): Cardiac Care Improvement

By: Gary P. Pisano and Maryam Golnaraghi

Explores the challenges confronting the CEO at the Brigham and Women's Hospital in the wake of radical changes in the health care environment. As pressures have risen for cost containment in health care, the hospital has embarked on a series of reengineering efforts to... View Details

Keywords: Consolidation; Health Care and Treatment; Mergers and Acquisitions; Organizational Change and Adaptation; Change Management; Management Teams; Operations; Innovation and Invention; Cost Management; Health Industry; Massachusetts

17 Dec 2001
Research & Ideas

Venture Capital: Hot Markets and Current Industry Trends

sleeves.—Jeff Fagnan Lisa L. Wiersma, Principal, Tribune Ventures, invests around core businesses or newspapers and television stations. Her firm, perhaps not too surprisingly, is particularly interested in ventures that are not driven by... View Details

Keywords: by Julia Hanna

Article

Ten Year Sunset Rule for Healthcare Regulation Is a Nonstarter and Discouragement to Post-COVID-19 Investment

By: Regina E. Herzlinger and Eugene Schneller

U.S. healthcare delivery has not benefitted from the same productivity growth as many other service industries, such as bricks and mortar retailing, a loss that has gravely diminished cost control and access. Regulatory capture, which creates barriers to venture... View Details

Keywords: Health Care; COVID-19; Regulation; Health Care and Treatment; Health Pandemics; Governing Rules, Regulations, and Reforms; Investment

Read Now

September 2015 (Revised February 2023)
Case

Emdeon's Acquisition of Change Healthcare: Innovating Transparency Solutions for Health Care Consumers

By: Regina E. Herzlinger, Jeet Guram and Aanchal Raj

Case describes acquisition of Change Healthcare, which provides health care cost and quality information, by Emdeon, a health information exchange, and discusses health care transparency. Emdeon is a billion-dollar company that has grown through acquisitions; at its... View Details

Keywords: Healthcare; Healthcare Industry; Healthcare Innovation; Health Care and Treatment; Acquisition; Integration; Analytics and Data Science; Mergers and Acquisitions; Competitive Strategy; Health Industry; United States

October 2012 (Revised October 2016)
Case

Predilytics

By: Robert F. Higgins and Annelena Lobb

The management team at Predilytics, a healthcare analytics firm, must decide whether to accept a Series A venture capital financing deal. The company provided analytic services to healthcare plans, typically Medicare Advantage plans, in efforts to draw conclusions from... View Details

Keywords: Analytics; Healthcare; Medicare; Health Care and Treatment; Mathematical Methods; Health Industry; New England; United States

June 2017
Case

Obesity Management at Kaiser Permanente: A New Mindset for Healthcare Delivery?

By: Kevin Schulman, Gregory Leya and Christina Beveridge

Kaiser Permanente (KP) is the largest managed care organization in the United States with over 10 million members. KP evolved from a prepayment or capitation model that focuses the organization around the efficiency of care and the health of the population it serves.... View Details

Keywords: Operations; Health Care and Treatment; Business Model; Strategy; Health Industry; United States

July 2019 (Revised May 2020)
Supplement

Piramal e-Swasthya (B): Considering Change

By: Rosabeth Moss Kanter and Joyce J. Kim

From 2008 to 2010 Anand Piramal ran a series of pilots for his digital healthcare startup, Piramal e-Swasthya (PeS) to “democratize healthcare” in rural areas of India. PeS ran into difficulties so Anand Piramal had to decide whether to continue the organization and,... View Details

Keywords: Entrepreneur; Healthcare; Innovation; Emerging Economies; Decision Choices and Conditions; Health Industry; India