Publications

Article

Do Equity Financing Cycles Matter?: Evidence from Biotechnology Alliances

By: Josh Lerner, Hilary Shane and Alexander Tsai

Keywords: Equity; Financing and Loans; Science; Alliances; Biotechnology Industry

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February 2012
Article

A 'Core Periphery' Framework to Navigate Emerging Market Governments—Qualitative Evidence from a Biotechnology Multinational

By: Prithwiraj Choudhury, James Geraghty and Tarun Khanna

We build on the emerging literature of influence-based models to study how multinational firms can navigate host governments. Our "core-periphery" framework posits that the actions that an MNC takes with actors in what we call the "periphery"—comprised of state,... View Details

Keywords: Emerging Markets; Multinational Firms and Management; Business and Government Relations; Power and Influence; Framework; Biotechnology Industry; Massachusetts; Brazil; China; Costa Rica; France; India

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February 1986 (Revised November 1992)
Case

Novo Industri A/S--1981

By: W. Carl Kester and Glynn Ferguson

This small but rapidly growing Danish biochemical company must choose among several financing opportunities that include a convertible Eurobond, a rights offering in Denmark and an issue of new common shares in the United States. The case involves a broad range of... View Details

Keywords: Capital Markets; Cost of Capital; Bonds; Stock Shares; Financing and Loans; Globalization; Biotechnology Industry; Biotechnology Industry; Denmark; United States

July 2013
Case

Sample6: Innovating to Make Food Safer

By: Robert F. Higgins and Kirsten Kester

Tim Curran, CEO of Sample6, a start-up biotechnology company developing a novel food safety diagnostics platform, must decide how to partner with food industry players. How can he best convince leaders in this mature industry to adopt a new technology and improve food... View Details

October 2016 (Revised February 2017)
Teaching Note

Alvogen

By: Daniel Isenberg, William R. Kerr and Alexis Brownell

Alvogen is an Icelandic pharmaceutical company that makes and sells generic drugs. Founder and CEO Robert Wessman is deciding whether to take on private equity investors willing to buy out all shareholders, merge with a large and publicly-traded US pharmaceutical... View Details

Keywords: Biotechnology; Globalization; Entrepreneurship; Biotechnology Industry

February 2003
Article

The Geography of Opportunity: Spatial Heterogeneity in Founding Rates and the Performance of Biotechnology Rirms

Keywords: Opportunities; Performance; Business Ventures; Biotechnology Industry

December 2006 (Revised January 2008)
Case

ViaGen: Revolutionizing the Livestock Industry

By: David E. Bell, Reed Martin and Mary L. Shelman

ViaGen has invested heavily to develop cloning technology for the livestock industry. Cloning has the potential to significantly improve the genetics of livestock, leading to higher quality meat, healthier animals, and more efficient production. Since 2003, the firm... View Details

Keywords: Animal-Based Agribusiness; Business Plan; Governing Rules, Regulations, and Reforms; Marketing Communications; Industry Structures; Business and Government Relations; Genetics; Commercialization; Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry

Article

Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology

By: Rebecca M. Henderson, Sarah Kaplan and Fiona Murray

Keywords: Management; Science; Technology; Biotechnology Industry

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June 1990 (Revised April 1993)
Teaching Note

Novo Industri A/S--1981, Teaching Note

By: W. Carl Kester

Teaching Note for (9-286-084). View Details

Keywords: Biotechnology Industry; Biotechnology Industry; Denmark; United States

Research Summary

Industrial competitiveness in high tech and science-based businesses

By: Willy C. Shih

How do emerging economies develop industrial and technical capabilities that overtake those of advanced economies? Are there some industrial sectors that are especially susceptible to such targeting? What will it take to restore America’s... View Details

Keywords: Technological Innovation; Technology Diffusion; Knowledge Flows; Competitive Advantage; Globalization; Manufacturing Industry; Manufacturing Industry; Manufacturing Industry; United States; China; Asia

03 Dec 2001
Research & Ideas

Healthcare Conference Looks At Ailing Industry

Mixing Risk And Reward The basic model that the biotechnology industry has followed for over twenty years is also changing, and for the better, according to panelists at a session titled "Will Equal... View Details

Keywords: by Martha Lagace; Health

October 2011
Case

Gene Sequencing: Staking a Position in an Expanding Industry

By: Richard G. Hamermesh, Mara Aspinall and Phillip Andrews

Towards the end of 2010, companies in the gene sequencing industry were pushing aggressive R&D programs to develop technologies and products in the race to sequence the entire human genome at a cost of $1,000. It remained to be seen when the "$1,000 genome" would... View Details

Keywords: Genetics; Business Growth and Maturation; Business Plan; Competition; Venture Capital; Biotechnology Industry

November 2016
Supplement

Alnylam Pharmaceuticals: Building Value from the IP Estate (B)

By: Vicki Sato, Willy Shih and Matt Higgins

The leader of a pioneering biotech company in the siRNA space weighs his options for scaling production capacity in advance of an anticipated commercial launch. Operational complexity and relative merits of in-house manufacturing versus a contractor model are... View Details

Keywords: Pharmaceutical Companies; Pharmaceutical Industry; Biotech; Biotechnology; Operational Complexity; Strategy; Manufacturing; Production; Strategic Planning; Intellectual Property; Biotechnology Industry; United States

20 May 2013
Op-Ed

Making America an Industrial Powerhouse Again

computer science, optics, and various engineering disciplines. We need to get over the outdated notion that manufacturing is "mature" and unconnected to science. Anyone who believes that should take a tour of a factory that produces semiconductors or View Details

Keywords: by Gary Pisano; Manufacturing

April 2008
Teaching Note

Viagen: Revolutioning the Livestock Industry (TN)

By: David E. Bell, Mary L. Shelman and Eliot Sherman

Teaching Note for [507021]. View Details

Keywords: Investment; Genetics; Production; Training; Customers; Supply Chain; Business Plan; Commercialization; Information Technology; Performance Efficiency; Governing Rules, Regulations, and Reforms; Industry Structures; Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry