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  • March 1992 (Revised June 2005)
  • Teaching Note

Monsanto's March into Biotechnology (A), Teaching Note

By: Dorothy Leonard-Barton and Alistair D. Williamson
Teaching Note for (9-690-009). View Details
Keywords: Biotechnology Industry
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Leonard-Barton, Dorothy, and Alistair D. Williamson. "Monsanto's March into Biotechnology (A), Teaching Note." Harvard Business School Teaching Note 692-045, March 1992. (Revised June 2005.)
  • 2000
  • Chapter

Strategic Alliances and Technology Licensing in Biotechnology

By: Josh Lerner
Keywords: Alliances; Corporate Strategy; Intellectual Property; Biotechnology Industry
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Lerner, Josh. "Strategic Alliances and Technology Licensing in Biotechnology." In Encyclopedia of Ethical, Legal and Policy Issues in Biotechnology, edited by Thomas H. Murray and Maxwell J. Mehlman, 1069–1079. New York: John Wiley & Sons, 2000.
  • 1988
  • Chapter

Joint Ventures and Collaboration in the Biotechnology Industry

By: Gary P. Pisano, W. Shan and David Teece
Keywords: Joint Ventures; Cooperation; Biotechnology Industry
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Pisano, Gary P., W. Shan, and David Teece. "Joint Ventures and Collaboration in the Biotechnology Industry." In International Collaborative Ventures in U.S. Manufacturing, edited by David Mowery. Cambridge, MA: Ballinger Publishing Company, 1988.
  • January 2000
  • Article

The Tragedy of the Commoners: Biotechnology and its Publics

By: Arthur A. Daemmrich
Keywords: Biotechnology Industry
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Daemmrich, Arthur A. "The Tragedy of the Commoners: Biotechnology and its Publics." Nature Biotechnology 18, no. 1 (January 2000): 2–4.
  • March 2011
  • Case

MorphoSys AG: The Evolution of a Biotechnology Business Model

By: Gary P. Pisano, Ryan Johnson and Carin-Isabel Knoop
In the biotech world, the 18-year-old Munich-based company MorphoSys was a rarity: it was profitable. The company achieved this profitability not by developing and selling its own drugs, but by licensing access to its proprietary library of human antibodies. Recently,... View Details
Keywords: Business Model; Profit; Intellectual Property; Rights; Risk Management; Digital Platforms; Product Development; Business and Shareholder Relations; Vertical Integration; Biotechnology Industry; Munich
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Pisano, Gary P., Ryan Johnson, and Carin-Isabel Knoop. "MorphoSys AG: The Evolution of a Biotechnology Business Model." Harvard Business School Case 611-046, March 2011.
  • Article

Do Equity Financing Cycles Matter?: Evidence from Biotechnology Alliances

By: Josh Lerner, Hilary Shane and Alexander Tsai
Keywords: Equity; Financing and Loans; Science; Alliances; Biotechnology Industry
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Lerner, Josh, Hilary Shane, and Alexander Tsai. "Do Equity Financing Cycles Matter?: Evidence from Biotechnology Alliances." Journal of Financial Economics 67, no. 3 (March 2003): 411–446. (Earlier versions distributed as HBS Working Paper No. 00-038 and NBER Working Paper No. 7464.)
  • February 2012
  • Article

A 'Core Periphery' Framework to Navigate Emerging Market Governments—Qualitative Evidence from a Biotechnology Multinational

By: Prithwiraj Choudhury, James Geraghty and Tarun Khanna
We build on the emerging literature of influence-based models to study how multinational firms can navigate host governments. Our "core-periphery" framework posits that the actions that an MNC takes with actors in what we call the "periphery"—comprised of state,... View Details
Keywords: Emerging Markets; Multinational Firms and Management; Business and Government Relations; Power and Influence; Framework; Biotechnology Industry; Massachusetts; Brazil; China; Costa Rica; France; India
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Choudhury, Prithwiraj, James Geraghty, and Tarun Khanna. "A 'Core Periphery' Framework to Navigate Emerging Market Governments—Qualitative Evidence from a Biotechnology Multinational." Global Strategy Journal 2, no. 1 (February 2012): 71–87.
  • Article

Using Equity Participation to Support Exchange: Evidence from the Biotechnology Industry

By: Gary P. Pisano
Keywords: Information; Biotechnology Industry
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Pisano, Gary P. "Using Equity Participation to Support Exchange: Evidence from the Biotechnology Industry." Journal of Law, Economics & Organization 5, no. 1 (Spring 1989): 109–126.
  • September 2020
  • Case

Minerva 2010: Turbulent Times

By: John R. Wells and Benjamin Weinstock
In 2010, amid a flurry of new discoveries, Cynthia Bamdad, founder and CEO of Minerva Biotechnologies Corporation (Minerva), raised $6.6 million to test her new cancer drugs in mice. It had been more than 6 years since she had announced that she and her small team at... View Details
Keywords: Biotechnology; Research; Product Development; Commercialization; Strategy
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Wells, John R., and Benjamin Weinstock. "Minerva 2010: Turbulent Times." Harvard Business School Case 721-390, September 2020.
  • Article

The Control of Technology Alliances: An Empirical Analysis of the Biotechnology Industry

By: Josh Lerner and Robert P. Merges
Keywords: Information Technology; Alliances; Information; Biotechnology Industry
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Lerner, Josh, and Robert P. Merges. "The Control of Technology Alliances: An Empirical Analysis of the Biotechnology Industry." Journal of Industrial Economics 46, no. 2 (June 1998): 125–156. (Special Symposium "Inside the Pin Factory": Empirical Studies Augmented by Manager Interviews.)
  • Article

The Governance of Innovation: Vertical Integration and Collaborative Arrangements in the Biotechnology Industry

By: Gary P. Pisano
Keywords: Governance; Innovation and Invention; Vertical Integration; Biotechnology Industry
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Pisano, Gary P. "The Governance of Innovation: Vertical Integration and Collaborative Arrangements in the Biotechnology Industry." Research Policy 20, no. 3 (June 1991): 237–249.
  • October 2016 (Revised February 2017)
  • Teaching Note

Alvogen

By: Daniel Isenberg, William R. Kerr and Alexis Brownell
Alvogen is an Icelandic pharmaceutical company that makes and sells generic drugs. Founder and CEO Robert Wessman is deciding whether to take on private equity investors willing to buy out all shareholders, merge with a large and publicly-traded US pharmaceutical... View Details
Keywords: Biotechnology; Globalization; Entrepreneurship; Biotechnology Industry
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Isenberg, Daniel, William R. Kerr, and Alexis Brownell. "Alvogen." Harvard Business School Teaching Note 817-057, October 2016. (Revised February 2017.)
  • 1989
  • Chapter

Collaborative Product Development and the Market for Know-How: Strategies and Structures in the Biotechnology Industry

By: Gary P. Pisano and Paul Mang
Keywords: Product Development; Innovation Strategy; Knowledge Management; Industry Structures; Biotechnology Industry
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Pisano, Gary P., and Paul Mang. "Collaborative Product Development and the Market for Know-How: Strategies and Structures in the Biotechnology Industry." In Research on Technological Innovation, Management, and Policy. Vol. 4, edited by Richard S. Rosenbloom and Robert A. Burgelman. Greenwich, CT: JAI Press, 1989.
  • Article

Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology

By: Rebecca M. Henderson, Sarah Kaplan and Fiona Murray
Keywords: Management; Science; Technology; Biotechnology Industry
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Henderson, Rebecca M., Sarah Kaplan, and Fiona Murray. "Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology." Industrial and Corporate Change 12, no. 2 (April 2003).
  • February 2003
  • Article

The Geography of Opportunity: Spatial Heterogeneity in Founding Rates and the Performance of Biotechnology Rirms

Keywords: Opportunities; Performance; Business Ventures; Biotechnology Industry
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Stuart, Toby E., and Olav Sorenson. "The Geography of Opportunity: Spatial Heterogeneity in Founding Rates and the Performance of Biotechnology Rirms." Research Policy 32, no. 2 (February 2003): 229–253.
  • 1997
  • Working Paper

R&D Performance, Collaborative Arrangements, and the Market-for-Know-How: A Test of the "Lemons" Hypothesis in Biotechnology

By: Gary P. Pisano
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Pisano, Gary P. R&D Performance, Collaborative Arrangements, and the Market-for-Know-How: A Test of the "Lemons" Hypothesis in Biotechnology. Harvard Business School Working Paper, No. 97-105, June 1997.
  • September 2020
  • Case

Minerva 2020: Clinical Trials

By: John R. Wells and Benjamin Weinstock
In March 2020, Dr. Cynthia Bamdad, founder and CEO of Minerva Biotechnologies Inc. (Minerva), was reviewing the first results of human clinical trials for the company’s novel CAR-T drug therapeutic, one of the first ever to target solid cancer tumors. The results... View Details
Keywords: Biotechnology; Strategic Decision Making; Entrepreneurship; Health Testing and Trials; Decision Choices and Conditions; Strategy
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Wells, John R., and Benjamin Weinstock. "Minerva 2020: Clinical Trials." Harvard Business School Case 721-391, September 2020.
  • July 2013
  • Case

Sample6: Innovating to Make Food Safer

By: Robert F. Higgins and Kirsten Kester
Tim Curran, CEO of Sample6, a start-up biotechnology company developing a novel food safety diagnostics platform, must decide how to partner with food industry players. How can he best convince leaders in this mature industry to adopt a new technology and improve food... View Details
Keywords: Data Analytics; Food Safety; Biotechnology; Nutrition; Entrepreneurship; Product; Partners and Partnerships; Food; Technological Innovation; Business Startups; Governing Rules, Regulations, and Reforms; Product Development; Agribusiness; Information Technology; Globalization; Performance Improvement; Safety; Technology Adoption; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States; Boston; Massachusetts
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Higgins, Robert F., and Kirsten Kester. "Sample6: Innovating to Make Food Safer." Harvard Business School Case 814-014, July 2013.
  • April 2014
  • Case

Merrimack Pharmaceuticals, Inc. (A)

By: Amy C. Edmondson, Bethany S. Gerstein and Melissa Valentine
In 2006, Merrimack Pharmaceuticals was a fast-growing biotechnology company. Its leadership team was divided over whether to keep R&D organized in functional departments or transition to interdisciplinary teams. As a small company, Merrimack's R&D organization had... View Details
Keywords: Teamwork; Interdisciplinary Collaboration; R&D; Biotechnology; Complexity; Innovation Management; Organizational Design; Groups and Teams; Collaborative Innovation and Invention; Research and Development; Biotechnology Industry; Biotechnology Industry
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Edmondson, Amy C., Bethany S. Gerstein, and Melissa Valentine. "Merrimack Pharmaceuticals, Inc. (A)." Harvard Business School Case 614-063, April 2014.
  • January 2018
  • Teaching Note

BeiGene

By: Willy Shih and Jimmy Zhang
Teaching Note for HBS No. 618-033. View Details
Keywords: Biotechnology; Drug Development; Corporate Strategy; Business Startups; Technological Innovation; Situation or Environment; Biotechnology Industry; Biotechnology Industry; China
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Shih, Willy, and Jimmy Zhang. "BeiGene." Harvard Business School Teaching Note 618-039, January 2018.
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