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  • August 2023
  • Case

Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company

By: Satish Tadikonda and Brad Prosek
Constellation Pharmaceuticals was a company focused on epigenetic therapies for cancer patients. Despite a promising start and an early deal with a leading biopharma company, the company weathered twin setbacks in the end of a major research collaboration and the... View Details
Keywords: Mergers and Acquisitions; Health Care and Treatment; Organizational Change and Adaptation; Research and Development; Business Strategy; Partners and Partnerships; Goals and Objectives; Pharmaceutical Industry; United States
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  • 27 Mar 2012
  • First Look

First Look: March 27

Corp. (B) Regina E. Herzlinger and Natalie KindredHarvard Business School Supplement 311-087 This case, the denouement to "PAREXEL International Corp. (A)," describes developments at PAREXEL and the biopharmaceutical View Details
Keywords: Carmen Nobel
  • 22 Jul 2014
  • First Look

First Look: July 22

Corporate Finance Attracting Long-Term Investors Through Integrated Thinking and Reporting: A Clinical Study of a Biopharmaceutical Company By: Knauer, Andrew, and George Serafeim Abstract—Faced with a large percentage of investors that... View Details
Keywords: Sean Silverthorne
  • 24 Jun 2008
  • First Look

First Look: June 24, 2008

Patenting on the Rate, Quality, and Direction of (Public) Research Output Authors: Pierre Azoulay, Waverly Ding, and Toby E. Stuart Periodical: Journal of Industrial Economics (forthcoming) Abstract We examine the influence of faculty... View Details
Keywords: Martha Lagace
  • 28 Jul 2015
  • First Look

First Look: July 28, 2015

country-level factors that limit firms' use of selective disclosure by intensifying scrutiny on them and by diffusing global norms to their headquarters countries. We test our hypotheses using a novel panel dataset of 4,750 public companies across many View Details
Keywords: Carmen Nobel
  • 22 Aug 2006
  • First Look

First Look: August 22, 2006

is a need for a fund like this at the time of the case. Supports discussion of specialized versus generalized venture capital funds. Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=805075 John Moran and the Orthopedics View Details
Keywords: Martha Lagace
  • 11 May 2010
  • First Look

First Look: May 11

this case:http://cb.hbsp.harvard.edu/cb/product/610031-PDF-ENG Revitalizing Dell Jan W. RivkinHarvard Business School Case 710-442 Dell Inc., with its vaunted Direct Model, defined success in the personal computer industry for more than a... View Details
Keywords: Martha Lagace
  • 17 Mar 2009
  • First Look

First Look: March 17, 2009

Agreements in Bio-Pharmaceuticals Authors:Juan Alcácer, John Cantwell, and Michelle Gittelman Publication:In Location of Biopharmaceutical Activity, edited by Iain M. Cockburn and Matthew J. Slaughter. NBER, forthcoming. Abstract As the... View Details
Keywords: Martha Lagace
  • 01 May 2007
  • First Look

First Look: May 1, 2007

possibility that the effects of FDI differ by sector. Second, we differentiate FDI based on objective qualitative industry characteristics including the average skill intensity and reliance on external capital. Third, we use a new dataset... View Details
Keywords: Sean Silverthorne
  • 07 Feb 2017
  • First Look

First Look at New Research: February 7

2017 New York: Oxford University Press Managing Risk in Reinsurance: From City Fires to Global Warming By: Hauter, Niels Viggo, and Geoffrey Jones, eds. Abstract—This is the first book to provide a comprehensive history of the reinsurance View Details
Keywords: Sean Silverthorne
  • 17 Aug 2010
  • First Look

First Look: August 17

companies increasingly are participants in open communities of science and technology. To participate in the system of exchange in such communities, firms often publicly disclose what would otherwise remain private discoveries. In a quantitative case study of one firm... View Details
Keywords: Martha Lagace
  • 27 Feb 2018
  • First Look

First Look at New Research and Ideas, February 27, 2018

developments in the Bangladesh ready-made garment industry after the fire at Tazreen Fashions factory, including formation of the Bangladesh Fire and Building Safety Accord (“Accord”) and the Alliance for Bangladesh Worker Safety... View Details
Keywords: Sean Silverthorne
  • 05 Dec 2017
  • First Look

First Look at New Research and Ideas, December 5, 2017

learning from parallel R&D projects in the setting of drug development. Leveraging the biopharmaceutical industry's unique characteristics to overcome barriers to measuring the project-level response to competitor news, I employ a... View Details
Keywords: Sean Silverthorne
  • 26 Apr 2011
  • Op-Ed

HBS Faculty Comment on Environmental Issues for Earth Day

Earth Day focuses the world's attention on the both the dangers and opportunities facing the planet. But sustainability and the intersection between business and the environment are issues that need to be addressed all the time, as cities grow, resources diminish, and... View Details
Keywords: by Staff; Energy; Utilities
  • 16 Dec 2014
  • First Look

First Look: December 16

Stages of Innovation Through the lens of biopharmaceutical contract research organization (CRO) PAREXEL, this case traces the evolution of the firm as it reinvents itself in response to the transformation of the CRO sector from a small,... View Details
Keywords: Sean Silverthorne
  • 14 Mar 2017
  • First Look

First Look at New Research, March 14

somewhere to stay. Clustering created positive externalities drawing new entrepreneurs into the industry who could also learn from knowledge spillovers. There were downsides to the new industry. The creation of the national image of a... View Details
Keywords: Sean Silverthorne
  • 16 Jul 2013
  • First Look

First Look: July 16

look at the creation of the Carnegie Tech Graduate School of Industrial Administration after World War II. This episode illustrates the increasingly successful claims of social scientists, backed by philanthropic foundations, on business... View Details
Keywords: Anna Secino
  • 18 Mar 2014
  • First Look

First Look: March 18

the ratings. Our tests examine whether these forms of disclosure reflect firms' real efforts to combat corruption or are cheap talk. We find that the ratings are related to enforcement and monitoring, country and industry corruption risk,... View Details
Keywords: Sean Silverthorne
  • 11 Sep 2012
  • First Look

First Look: September 11

expansions of biopharmaceutical firms (by both new establishments and employment increase in existing establishments) in the U.S. in 1993-2005. We consider all activities in the value chain and allow location choices to vary by R&D,... View Details
Keywords: Sean Silverthorne

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