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      • Faculty Publications  (525)

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      • June 2003
      • Teaching Note

      Discovering the Future: R&D Strategy at Merck (TN)

      By: Gary P. Pisano
      Teaching Note for (9-601-086). View Details
      Keywords: Pharmaceutical Industry
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      Pisano, Gary P. "Discovering the Future: R&D Strategy at Merck (TN)." Harvard Business School Teaching Note 603-137, June 2003.
      • April 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (A)

      By: Sandra J. Sucher and Stacy McManus
      Preliminary results from Phase 1 clinical trials of a newly developed compound, STI571, showed that 31 out of 31 patients with chronic myelogenous leukemia (CML) had their blood counts return to normal. In the world of oncology, this was unheard of. This was the... View Details
      Keywords: Decision Making; Health Testing and Trials; Innovation and Invention; Markets; Distribution; Product Development; Production; Problems and Challenges; Research; Research and Development; Complexity; Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (A)." Harvard Business School Case 603-043, April 2003. (Revised October 2004.)
      • April 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (B)

      By: Sandra J. Sucher and Stacy McManus
      When Dr. Daniel Vasella learned of the early Phase 1 trial results, he immediately decided what course of action Novartis would take. Students will be able to examine and assess the concrete steps, and the rationale behind them, that Novartis took in response to this... View Details
      Keywords: Decision Making; Moral Sensibility; Innovation and Invention; Distribution; Product Development; Production; Problems and Challenges; Research and Development; Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (B)." Harvard Business School Case 603-044, April 2003. (Revised October 2004.)
      • February 2003 (Revised April 2004)
      • Case

      Pharmaceutical Industry, The: Challenges in the New Century

      By: Stephen P. Bradley and James Weber
      Provides a broad overview of the numerous internal and external forces that were driving change in the global pharmaceutical industry in 2003. These forces--including downward price pressures, political and social pressures, increased development costs, new... View Details
      Keywords: Business Model; Change; Cost; Price; Globalization; Government and Politics; Brands and Branding; Industry Growth; Society; Competition; Consolidation; Technology; Pharmaceutical Industry
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      Bradley, Stephen P., and James Weber. "Pharmaceutical Industry, The: Challenges in the New Century." Harvard Business School Case 703-489, February 2003. (Revised April 2004.)
      • February 2003 (Revised August 2005)
      • Case

      UCB (A): Managing Information for Globalization and Innovation

      By: F. Warren McFarlan and Brian DeLacey
      This case presents a complex total MIS strategy case for a $3 billion European pharmaceutical/chemicals company based in Brussels. It covers corporate strategy alignment of IT portfolio, IT operations issues, and global coordination of IT. View Details
      Keywords: Information Technology; Operations; System; Corporate Strategy; Investment Portfolio; Globalization; Pharmaceutical Industry; Pharmaceutical Industry; Brussels
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      McFarlan, F. Warren, and Brian DeLacey. "UCB (A): Managing Information for Globalization and Innovation." Harvard Business School Case 303-091, February 2003. (Revised August 2005.)
      • Article

      Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology

      By: Rebecca M. Henderson, Sarah Kaplan and Fiona Murray
      Keywords: Management; Science; Technology; Biotechnology Industry
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      Henderson, Rebecca M., Sarah Kaplan, and Fiona Murray. "Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology." Industrial and Corporate Change 12, no. 2 (April 2003).
      • December 2002
      • Teaching Note

      Abgenix and the XenoMouse (TN)

      By: John T. Gourville
      Teaching Note for (501-061). View Details
      Keywords: Health Testing and Trials; Decision Choices and Conditions; Sales; Product Development; Joint Ventures; Pharmaceutical Industry; Pharmaceutical Industry
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      Gourville, John T. "Abgenix and the XenoMouse (TN)." Harvard Business School Teaching Note 503-046, December 2002.
      • December 2002
      • Article

      Knowledge Seeking and Location Choice of Foreign Direct Investment in the United States

      By: Juan Alcacer and Wilbur Chung
      To what extent do firms go abroad to access technology available in other locations? This paper examines whether and when state technical capabilities attract foreign investment in manufacturing from 1987-1993. We find that on average state R&D intensity does not... View Details
      Keywords: Knowledge Acquisition; Foreign Direct Investment; Research and Development; Information Technology; Production; Geographic Location; United States
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      Alcacer, Juan, and Wilbur Chung. "Knowledge Seeking and Location Choice of Foreign Direct Investment in the United States." Management Science 48, no. 12 (December 2002): 1534–1554.
      • November 2002
      • Compilation

      Four Principles of Biomedical Ethics: Definitions and Examples

      By: Sandra J. Sucher
      Introduces four principles of biomedical ethics, excerpted from Principles of Biomedical Ethics, Tom L. Beauchamp and James F. Childress (Oxford University Press, 2001). The principles provide a conceptual framework for the analysis and resolution of moral problems... View Details
      Keywords: Framework; Moral Sensibility; Health Care and Treatment; Distribution; Problems and Challenges; Research; Emotions; Management Analysis, Tools, and Techniques; Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J. "Four Principles of Biomedical Ethics: Definitions and Examples." Harvard Business School Compilation 603-079, November 2002.
      • October 2002 (Revised June 2003)
      • Background Note

      New Frontiers in Target Discovery and Validation

      By: Regina E. Herzlinger, Niv Caviar, Jon Chatterton and Andrea Lynn
      Explains Immusol and Novartis's technology. View Details
      Keywords: Information Technology; Technological Innovation; Pharmaceutical Industry
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      Herzlinger, Regina E., Niv Caviar, Jon Chatterton, and Andrea Lynn. "New Frontiers in Target Discovery and Validation." Harvard Business School Background Note 303-054, October 2002. (Revised June 2003.)
      • September 2002 (Revised August 2014)
      • Case

      Cardinal Health (A): The Medicine Shoppe Acquisition

      By: Regina E. Herzlinger, Miguel Abecasis and Brenda Cheng
      Robert Walter, the founder and CEO of Cardinal Health, a pharmaceutical distributor, is contemplating the purchase of Medicine Shoppe, a chain of apothecaries. The purchase might be construed as competition against his own drugstore customers. But one of its many... View Details
      Keywords: Mergers and Acquisitions; Business Strategy; Competitive Advantage; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry
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      Herzlinger, Regina E., Miguel Abecasis, and Brenda Cheng. "Cardinal Health (A): The Medicine Shoppe Acquisition." Harvard Business School Case 303-043, September 2002. (Revised August 2014.)
      • July 2002 (Revised December 2002)
      • Case

      Phase Two: The Pharmaceutical Industry Responds to AIDS

      By: Debora L. Spar
      Describes how major pharmaceutical firms changed their strategy and pricing policies in the years 2000 to 2002 to respond to the growing AIDS epidemic in Africa. View Details
      Keywords: International Finance; Health Pandemics; Corporate Social Responsibility and Impact; Pharmaceutical Industry; Africa
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      Spar, Debora L., and Nick Bartlett. "Phase Two: The Pharmaceutical Industry Responds to AIDS." Harvard Business School Case 703-005, July 2002. (Revised December 2002.)
      • July 2002
      • Article

      Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery

      By: Stefan Thomke and Walter Kuemmerle
      Keywords: Assets; Information Technology; Change; Health
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      Thomke, Stefan, and Walter Kuemmerle. "Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery." Strategic Management Journal 23, no. 7 (July 2002): 619–635.
      • June 2002 (Revised November 2005)
      • Case

      Life, Death, and Property Rights: The Pharmaceutical Industry Faces AIDS in Africa

      By: Debora L. Spar
      In the final years of the 20th century, the world was hit by a plague of epidemic proportions--AIDS, a life-threatening disease that remained stubbornly immune to any cure or vaccine. In the developed nations of the West, AIDS was slowly brought under control through a... View Details
      Keywords: Patents; Health Pandemics; Corporate Social Responsibility and Impact; Pharmaceutical Industry; Africa
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      Spar, Debora L., and Nick Bartlett. "Life, Death, and Property Rights: The Pharmaceutical Industry Faces AIDS in Africa." Harvard Business School Case 702-049, June 2002. (Revised November 2005.)
      • May 2002 (Revised October 2005)
      • Case

      Marketing Antidepressants: Prozac and Paxil

      By: Youngme E. Moon and Kerry Herman
      Describes the marketing of Prozac and Paxil, two of the best-selling mental health drugs in history. Set in 2001, several months before the expiration of Prozac's patent, Eli Lilly (Prozac's manufacturer) and GlaxoSmithKline (Paxil's manufacturer) must decide how to... View Details
      Keywords: Patents; Product Positioning; Competition; Ethics; Value; Health Care and Treatment; Brands and Branding; Pharmaceutical Industry; United States
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      Moon, Youngme E., and Kerry Herman. "Marketing Antidepressants: Prozac and Paxil." Harvard Business School Case 502-055, May 2002. (Revised October 2005.)
      • May 2002 (Revised December 2003)
      • Teaching Note

      Medicines Company, The TN

      By: John T. Gourville
      Teaching Note for (9-502-006). View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Gourville, John T. "Medicines Company, The TN." Harvard Business School Teaching Note 502-076, May 2002. (Revised December 2003.)
      • April 2002
      • Supplement

      Grey Warner, Merck Latin America

      By: Michael Beer
      Grey Warner, the vice president of Merck's Latin America region, discusses the challenges raised in the case and the lessons learned. View Details
      Keywords: Strategic Planning; Values and Beliefs; Change Management; Problems and Challenges; Management Teams; Pharmaceutical Industry; Latin America
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      Beer, Michael. "Grey Warner, Merck Latin America." Harvard Business School Video Supplement 402-801, April 2002.
      • February 2002
      • Case

      Fighting AIDS and Pricing Drugs

      By: John T. Gourville
      In early 2001, makers of AIDS drugs were suing to prevent developing countries from violating their patents. The issue was driven by price. The developing countries could not afford the market price for these drugs. At the same time, the drug companies were reluctant... View Details
      Keywords: Developing Countries and Economies; Patents; Price; Strategy; Globalized Markets and Industries; Pharmaceutical Industry
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      Gourville, John T. "Fighting AIDS and Pricing Drugs." Harvard Business School Case 502-061, February 2002.
      • 2002
      • Chapter

      Pharmaceutical Biotechnology

      By: Gary P. Pisano
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Pisano, Gary P. "Pharmaceutical Biotechnology." In Technological Innovation & Economic Performance, edited by Benn Steil, David G. Victor, and Richard R. Nelson. Princeton: Princeton University Press, 2002.
      • September 2001
      • Supplement

      Millennium Pharmaceuticals, Inc. (B)

      By: Stefan H. Thomke and Ashok Nimgade
      Supplements the (A) case. View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry; Cambridge
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      Thomke, Stefan H., and Ashok Nimgade. "Millennium Pharmaceuticals, Inc. (B)." Harvard Business School Supplement 602-063, September 2001.
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