Publications

September 2022
Article

Find and Replace: R&D Investment Following the Erosion of Existing Products

By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor

How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first... View Details

Keywords: R＆D Investments; Drug Development; Product Shocks; M＆A; Biopharmaceutical Industry; FDA; System Shocks; Research and Development; Investment; Decision Making; Pharmaceutical Industry

November 3, 2020
Article

Gender Differences in COVID-19 Attitudes and Behavior: Panel Evidence from Eight Countries

By: Vincenzo Galasso, Vincent Pons, Paola Profeta, Michael Becher, Sylvain Brouard and Martial Foucault

Using original data from two waves of a survey conducted in March and April 2020 in eight OECD countries (N = 21,649), we show that women are more likely to see COVID-19 as a very serious health problem, to agree with restraining public policy measures adopted in... View Details

Keywords: COVID-19; Health Pandemics; Attitudes; Behavior; Gender; Policy; Governance Compliance

December 2004 (Revised March 2007)
Case

Cutlass Capital, L.P.

By: Richard G. Hamermesh and Brian DeLacey

David Hetz and Jon Osgood are forming a new venture capital fund in 2001 to invest in health care start-ups. Describes their fundraising activities at a time when venture capital investing has reached an all-time high. Although their background skills and experiences... View Details

Keywords: Venture Capital; Negotiation Process; Entrepreneurship; Investment Funds; Health Care and Treatment; Business Startups; Health Industry; United States

2022
Report

The First Four Healthy Building Strategies Every Building Should Pursue to Reduce Risk from COVID-19

By: Joseph G. Allen, Emily Jones, Marissa V. Rainbolt, Linsey C. Marr, David Michaels, Leslie R. Cadet, Shelly L. Miller, Meira Levinson, Lidia Morawska, Richard L. Corsi, Nira R. Pollock, Yuguo Li, Alasdair P.S. Munro, Kelly Grier, Qingyan Chen, John D. Macomber and Xiaodong Cao

Understanding of the most probable transmission routes and identifying the risk environments for disease spread should always be among the first critical steps in the response to future disease threats. This is one of the most vital public health lessons of the... View Details

Keywords: Health Pandemics; Buildings and Facilities; Risk and Uncertainty; Health Industry; Health Industry; Health Industry

January 2004 (Revised September 2004)
Background Note

Confidentiality in Settlement Negotiations: Ethics & Law

By: Michael A. Wheeler, Dana Nelson and Gillian Morris

Legal policy has a long history of protecting confidentiality of negotiations that are designed to produce settlement. However, within the past several decades there has been a significant push toward openness. Compelling arguments support confidentiality: It helps... View Details

Keywords: Ethics; Lawsuits and Litigation; Attorney and Client Relationships; Policy; Corporate Disclosure; Negotiation

April 2007 (Revised March 2008)
Case

Dr. Iqbal Survé at Sekunjalo Investment Group (A)

By: Linda A. Hill and Emily Stecker

Dr. Iqbal Surve, a self-described "medical doctor, philanthropist, and social entrepreneur," was born in 1963 and grew up in poverty, like virtually all non-white South Africans during apartheid. During the 1970s and 1980s, he served in leadership positions in the ANC,... View Details

Keywords: Crime and Corruption; Social Entrepreneurship; Investment; Leadership; Corporate Social Responsibility and Impact; Partners and Partnerships; South Africa

July 2020
Teaching Note

COVID-19: The Global Shutdown

By: Laura Alfaro and Sarah Jeong

In the first months of 2020, a pandemic overwhelmed the world. COVID-19, commonly known as the coronavirus, spread from China and created a severe public health emergency across countries. While an immediate fear of the disease’s impact on human life permeaacted... View Details

Keywords: COVID-19; Health Pandemics; Trade; Microeconomics; Macroeconomics; Financial Crisis; Economy; Policy; Governance; Economic Systems; Economic Slowdown and Stagnation; Economic Sectors

January 2023
Case

Thomas Buberl: Refounding AXA

By: Hubert Joly, Mihir Desai and Amram Migdal

In 2022, AXA and its CEO Thomas Buberl faced new types of challenges, including systemic risks such as climate change, geopolitical instability, public health crises, and social tensions caused by economic risks. AXA was one of the world’s largest insurers. Since... View Details

03 Jun 2020
Research & Ideas

Who Guarantees Your Workplace Is Safe for Return?

Here are key requirements to ask of any service provider offering to certify your work setting as a healthy building. These best practices apply for employers, employees, and customers alike. Our research over many decades in public View Details

Keywords: by John Macomber and Joseph Allen; Real Estate

02 Jan 2018
First Look

First Look at New Research and Ideas, January 3, 2018

in U.S. politics: CEOs are taking very public stands on thorny political issues that have nothing to do with their firms’ bottom lines. Business leaders like Tim Cook of Apple, Howard Schultz of Starbucks, and Marc Benioff of... View Details

Keywords: Sean Silverthorne

December 2010
Case

Oral Rehydration Therapy

By: Nava Ashraf and Claire Qureshi

This case highlights the puzzlingly high rate of diarrhea-related child mortality in developing countries despite the existence of a simple, effective treatment: oral rehydration therapy (ORT). ORT treated extreme dehydration caused by diarrhea, which was a leading... View Details

Keywords: Health Care and Treatment; Innovation Strategy; Problems and Challenges; Developing Countries and Economies; Technological Innovation; Distribution Channels; Emerging Markets; Consumer Behavior; Performance Consistency; Performance Evaluation; Health Industry; Africa; Asia

Summer 2021
Article

The Cost and Evolution of Quality at Cipla Ltd, 1935–2016

By: Muhammad H. Zaman and Tarun Khanna

This article examines the evolution of Indian pharmaceutical manufacturer Cipla towards producing drugs that met the quality standards of European and U.S. regulators. It employs new research in Cipla’s corporate archives, the Creating Emerging Markets database, and... View Details

Keywords: Cipla; Pharmaceuticals; Drug Quality; Generics; Quality; Standards; Information Technology; Cost; Organizational Culture; Business History; Pharmaceutical Industry; India

Article

Big Names or Big Ideas: Do Peer-Review Panels Select the Best Science Proposals?

By: Danielle Li and Leila Agha

This paper examines the success of peer-review panels in predicting the future quality of proposed research. We construct new data to track publication, citation, and patenting outcomes associated with more than 130,000 research project (R01) grants funded by the U.S.... View Details

Keywords: Patents; Research; Entrepreneurship; Forecasting and Prediction; Innovation and Invention; Business and Government Relations; United States

24 Aug 2016
Research & Ideas

Can Obamacare Be Saved?

On August 15th, Aetna announced that it would reduce by 80 percent its participation in the Obama administration’s public exchanges for health insurance policies in 2017, citing significant financial losses.... View Details

Keywords: by John A. Quelch and Emily Boudreau; Health; Health

February 2014
Article

Developing a System to Track Meaningful Outcome Measures in Head and Neck Cancer Treatment

By: Ronald S. Walters, Heidi W. Albright, Randal S. Weber, Thomas W. Feeley, Ehab Y. Hanna, Scott B. Cantor, Carol M. Lewis and Thomas W. Burke

The health care industry, including consumers, providers, and payers of health care, recognize the importance of developing meaningful, patient-centered measures. This article describes our experience using an existing electronic medical record largely based on free... View Details

Keywords: Cancer Treatment; Cancer Care In The U.S.; Outcomes Measurement; Health Care and Treatment; Measurement and Metrics; Health Industry; North and Central America

2022
Working Paper

The Lifesaving Benefits of Convenient Infrastructure: Quantifying the Mortality Impact of Abandoning Shallow Tubewells Contaminated by Arsenic in Bangladesh

By: Nina Buchmann, Erica Field, Rachel Glennerster and Reshmaan Hussam

We document the consequences of a public health campaign which led to the sudden abandonment of local water infrastructure by one-fifth of Bangladesh’s population. Households who experienced quasi-randomly distributed arsenic contamination, and thus were likely to... View Details

Keywords: Child Mortality; Arsenic; Unintended Consequences; Health Disorders; Safety; Outcome or Result; Bangladesh