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      • March 2001 (Revised September 2002)
      • Case

      Merck Latin America (C): Brazil

      By: Michael Beer and James Weber
      Examines Merck's change effort in Brazil from the perspective of the local employees. View Details
      Keywords: Change Management; Cross-Cultural and Cross-Border Issues; Multinational Firms and Management; Employees; Operations; Perspective; Pharmaceutical Industry; Brazil
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      Beer, Michael, and James Weber. "Merck Latin America (C): Brazil." Harvard Business School Case 401-031, March 2001. (Revised September 2002.)
      • March 2001 (Revised September 2002)
      • Case

      Merck Latin America (D): Mexico

      By: Michael Beer and James Weber
      Examines Merck's change effort in Mexico from the perspective of the local employees. View Details
      Keywords: Change Management; Cross-Cultural and Cross-Border Issues; Multinational Firms and Management; Employees; Operations; Perspective; Pharmaceutical Industry; Mexico
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      Beer, Michael, and James Weber. "Merck Latin America (D): Mexico." Harvard Business School Case 401-032, March 2001. (Revised September 2002.)
      • March 2001 (Revised June 2017)
      • Teaching Note

      Vyaderm Pharmaceuticals: The EVA Decision

      By: Robert Simons and Indra A. Reinbergs
      Teaching Note for (9-101-019). View Details
      Keywords: Pharmaceutical Industry; Washington (state, US)
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      Simons, Robert, and Indra A. Reinbergs. "Vyaderm Pharmaceuticals: The EVA Decision." Harvard Business School Teaching Note 101-043, March 2001. (Revised June 2017.)
      • February 2001 (Revised July 2006)
      • Case

      Discovering the Future: R&D Strategy at Merck

      By: Gary P. Pisano
      Given explosive growth in technologies for drug discovery, how does Merck remain competitive in an industry that is fragmented and continues to consolidate? View Details
      Keywords: Competitive Strategy; Research and Development; Pharmaceutical Industry
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      Pisano, Gary P. "Discovering the Future: R&D Strategy at Merck." Harvard Business School Case 601-086, February 2001. (Revised July 2006.)
      • February 2001
      • Teaching Note

      CVS: The Web Strategy TN

      By: John A. Deighton
      Teaching Note for (9-500-008). View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Deighton, John A. "CVS: The Web Strategy TN." Harvard Business School Teaching Note 501-064, February 2001.
      • January 2001
      • Case

      Merck Global Health Initiatives (A)

      By: James E. Austin, Diana Barrett and James Weber
      The case series focuses on Merck's drug donation program and then raises new issues facing management about what to do about HIV/AIDS in Africa given the company's development of a new therapy. Describes collaboration among many parties including the Gates Foundation,... View Details
      Keywords: Programs; Philanthropy and Charitable Giving; Health Disorders; Health Care and Treatment; Private Sector; Public Sector; Alliances; Problems and Challenges; Pharmaceutical Industry; Botswana
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      Austin, James E., Diana Barrett, and James Weber. "Merck Global Health Initiatives (A)." Harvard Business School Case 301-088, January 2001.
      • January 2001 (Revised May 2003)
      • Case

      Novartis Pharma: The Business Unit Model

      By: Srikant M. Datar, Carin-Isabel Knoop and Cate Reavis
      In June 2000, Novartis reorganized its pharmaceutical business to form global business units in oncology, transplantation, ophthalmology, and mature products. The remaining primary care products continued to be managed within global functions (e.g., R&D and marketing).... View Details
      Keywords: Restructuring; Recruitment; Product Marketing; Organizational Structure; Problems and Challenges; Health Industry; Health Industry
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      Datar, Srikant M., Carin-Isabel Knoop, and Cate Reavis. "Novartis Pharma: The Business Unit Model." Harvard Business School Case 101-030, January 2001. (Revised May 2003.)
      • January 2001
      • Case

      Abgenix and the XenoMouse

      By: Robert J. Dolan
      Abgenix has a unique method for generating antibodies useful in treating a number of diseases, including cancer. In early 2000, the company's cancer has performed very well in animal testing and is moving to early stage human testing. Abgenix must decide whether to... View Details
      Keywords: Product Development; Marketing Strategy; Health Testing and Trials; Risk and Uncertainty; Technological Innovation; Innovation Strategy; Science-Based Business; Biotechnology Industry
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      Dolan, Robert J. "Abgenix and the XenoMouse." Harvard Business School Case 501-061, January 2001.
      • January 2001 (Revised July 2003)
      • Case

      Pharmacyclics: Financing Research & Development

      By: Malcolm P. Baker, Richard S. Ruback and Aldo Sesia
      Pharmacyclics (NASDAQ: PCYC), a pharmaceutical company that manufactures products that will improve existing therapeutic treatments for cancer, arteriosclerosis, and retinal disease, was considering a $60 million private placement in February 2000. The company had more... View Details
      Keywords: Valuation; Cash Flow; Financing and Loans; Business Startups; Financial Strategy; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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      Baker, Malcolm P., Richard S. Ruback, and Aldo Sesia. "Pharmacyclics: Financing Research & Development." Harvard Business School Case 201-056, January 2001. (Revised July 2003.)
      • 2001
      • Chapter

      Publicly Funded Science and the Productivity of the Pharmaceutical Industry

      By: Rebecca Henderson and Ian Cockburn
      U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details
      Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry
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      Henderson, Rebecca, and Ian Cockburn. "Publicly Funded Science and the Productivity of the Pharmaceutical Industry." In Innovation Policy and the Economy, Volume 1, edited by Adam B. Jaffe, Josh Lerner, and Scott Stern, 1–34. MIT Press, 2001.
      • December 2000 (Revised January 2001)
      • Background Note

      Promise of Functional Foods, The

      By: Ray A. Goldberg, Carin-Isabel Knoop and Laure Mougeot Stroock
      This case presents a definition of functional foods or nutraceuticals (food or food ingredients that could provide a health benefit beyond the traditional nutrients they contain), a description of some of the major obstacles to their commercialization and... View Details
      Keywords: Food; Private Sector; Public Sector; Health; Product Development; Production; Commercialization; Food and Beverage Industry; Food and Beverage Industry
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      Goldberg, Ray A., Carin-Isabel Knoop, and Laure Mougeot Stroock. "Promise of Functional Foods, The." Harvard Business School Background Note 901-013, December 2000. (Revised January 2001.)
      • October 2000 (Revised March 2003)
      • Case

      Merck & Company: Evaluating a Drug Licensing Opportunity

      By: Richard S. Ruback and David B Krieger
      This explores the valuation of an opportunity to license a compound before it enters clinical trials. Describes Merck's decision tree evaluation process is presented. Information required to evaluate a specific licensing opportunity is provided, including the costs of... View Details
      Keywords: Decision Making; Cost vs Benefits; Opportunities; Valuation; Outcome or Result; Pharmaceutical Industry
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      Ruback, Richard S., and David B Krieger. "Merck & Company: Evaluating a Drug Licensing Opportunity." Harvard Business School Case 201-023, October 2000. (Revised March 2003.)
      • 2000
      • Chapter

      Millennium Pharmaceuticals, Inc.

      By: S. Thomke and A. Nimgade
      Keywords: Pharmaceutical Industry
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      Thomke, S., and A. Nimgade. "Millennium Pharmaceuticals, Inc." In Inside Biotechnology and Pharmaceuticals.Harvard Business School From the Field Series. Boston, MA: Harvard Business School Publishing, 2000.
      • October 2000
      • Case

      Procter & Gamble Italy: The Pringles Launch (A)

      By: Roy D. Shapiro
      Procter & Gamble's (P&G) Pringles potato chips have been a very successful brand. This case reviews the development and first launch in the United States, then in markets around the world. Italy is one of the last countries where Pringles will be launched. Should P&G... View Details
      Keywords: Globalized Markets and Industries; Brands and Branding; Marketing Strategy; Product Launch; Emerging Markets; Product Development; Adoption; Value Creation; Pharmaceutical Industry; United States
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      Shapiro, Roy D. "Procter & Gamble Italy: The Pringles Launch (A)." Harvard Business School Case 601-070, October 2000.
      • October 2000
      • Teaching Note

      Kendle International Inc. TN

      By: Dwight B. Crane and Indra Reinbergs
      Teaching Note for (9-200-033). View Details
      Keywords: Biotechnology Industry; Biotechnology Industry
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      Crane, Dwight B., and Indra Reinbergs. "Kendle International Inc. TN." Harvard Business School Teaching Note 201-014, October 2000.
      • October 2000
      • Supplement

      Hans Fritz at Novartis Thailand (C)

      By: Carin-Isabel Knoop and Michael Y. Yoshino
      Supplements the (A) case. View Details
      Keywords: Pharmaceutical Industry; Thailand
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      Knoop, Carin-Isabel, and Michael Y. Yoshino. "Hans Fritz at Novartis Thailand (C)." Harvard Business School Supplement 301-054, October 2000.
      • October 2000
      • Supplement

      Hans Fritz at Novartis Thailand (D): The First 18 Months

      By: Michael Y. Yoshino and Carin-Isabel Knoop
      Supplements the (A) case. View Details
      Keywords: Pharmaceutical Industry; Thailand
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      Yoshino, Michael Y., and Carin-Isabel Knoop. "Hans Fritz at Novartis Thailand (D): The First 18 Months." Harvard Business School Supplement 301-055, October 2000.
      • October 2000 (Revised June 2017)
      • Case

      Vyaderm Pharmaceuticals: The EVA Decision

      By: Robert Simons and Indra A. Reinbergs
      In 2016, the new CEO of Vyaderm Pharmaceuticals introduces an Economic Value Added (EVA) program to focus the company on long-term shareholder value. The EVA program consists of three elements: EVA centers (business units), EVA drivers (operational practices that... View Details
      Keywords: Compensation and Benefits; Employee Relationship Management; Economic Growth; Economic Systems; Management; Motivation and Incentives; Organizational Design; Organizational Structure; Performance Evaluation; Decision Choices and Conditions; Pharmaceutical Industry; Washington (state, US)
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      Simons, Robert, and Indra A. Reinbergs. "Vyaderm Pharmaceuticals: The EVA Decision." Harvard Business School Case 101-019, October 2000. (Revised June 2017.)
      • 2000
      • Chapter

      In Search of Dynamic Capabilities: The Origins of R&D Competence in Biopharmaceuticals

      By: Gary P. Pisano
      Keywords: Competency and Skills; Research and Development; Pharmaceutical Industry; Pharmaceutical Industry
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      Pisano, Gary P. "In Search of Dynamic Capabilities: The Origins of R&D Competence in Biopharmaceuticals." Chap. 5 in The Nature and Dynamics of Organizational Capabilities, edited by Giovanni Dosi, Richard Nelson, and Sidney Winter, 129–154. New York: Oxford University Press, 2000.
      • 2000
      • Chapter

      Measuring Competence? Exploring Firm Effects in Drug Discovery

      By: Rebecca M. Henderson and Iain Cockburn
      Keywords: Competency and Skills; Measurement and Metrics; Research and Development; Innovation and Invention; Pharmaceutical Industry
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      Henderson, Rebecca M., and Iain Cockburn. "Measuring Competence? Exploring Firm Effects in Drug Discovery." Chap. 6 in The Nature and Dynamics of Organizational Capabilities, edited by Giovanni Dosi, Richard Nelson, and Sidney Winter. New York: Oxford University Press, 2000.
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