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  • All HBS Web  (8,491)
    • People  (28)
    • News  (977)
    • Research  (6,006)
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  • 1996
  • Chapter

Note on New Drug Development in the United States

By: S. Thomke and A. Nimgade
Keywords: Product Development; Pharmaceutical Industry; United States
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Thomke, S., and A. Nimgade. "Note on New Drug Development in the United States." In Strategic Management of Technology and Innovation. 2nd ed. by R. Burgelman, M. A. Maidique, and S. C. Wheelwright. Burr Ridge, IL: Irwin/McGraw-Hill, 1996.
  • May 2021
  • Case

The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease

By: Amitabh Chandra, Spencer Lee-Rey and Caroline Marra
This case explores incentives for rare disease drug development by chronicling the role of the Spinal Muscular Atrophy (SMA) Foundation in forming strategic partnerships with the scientific research community and pharmaceutical developers to transform the trajectory... View Details
Keywords: Innovation and Invention; Strategy; Business or Company Management; Society; Health; Public Administration Industry; Public Administration Industry; United States
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Chandra, Amitabh, Spencer Lee-Rey, and Caroline Marra. "The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease." Harvard Business School Case 621-112, May 2021.
  • 2009
  • Working Paper

Broadening Focus: Spillovers, Complementarities and Specialization in the Hospital Industry

By: Jonathan R. Clark and Robert S. Huckman
The long-standing argument that focused operations outperform others stands in contrast to claims about the benefits of broader operational scope. The performance benefits of focus are typically attributed to reduced complexity, lower uncertainty, and the development... View Details
Keywords: Health Care and Treatment; Medical Specialties; Performance Capacity; Diversification; Health Industry
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Clark, Jonathan R., and Robert S. Huckman. "Broadening Focus: Spillovers, Complementarities and Specialization in the Hospital Industry." Harvard Business School Working Paper, No. 09-120, April 2009. (Revised April 2011.)
  • December 2014
  • Article

When to Sell Your Idea: Theory and Evidence from the Movie Industry

By: Hong Luo
I study a model of investment and sale of ideas and test its empirical implications using a novel data set from the market for original movie ideas. Consistent with the theoretical results, I find that buyers are reluctant to meet unproven sellers for early-stage... View Details
Keywords: Market For Ideas; Information Asymmetry; Expropriation Risk; Intermediary; Intellectual Property Protection; Strategy; Intellectual Property; Film Entertainment; Sales; Entertainment and Recreation Industry
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Luo, Hong. "When to Sell Your Idea: Theory and Evidence from the Movie Industry." Management Science 60, no. 12 (December 2014): 3067–3086.
  • January 2000
  • Supplement

Basic Statistics from the World Bank's World Development Report 1998/1999

By: Julio J. Rotemberg
Supplements National Income Accounting and The Origins of National Income Accounting. View Details
Keywords: Business Organization; History; Earnings Management; Financial Institutions; International Finance; International Accounting; Business Earnings; Mathematical Methods; Reports; Economic Growth; Commercial Banking; Financial Services Industry
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Rotemberg, Julio J. "Basic Statistics from the World Bank's World Development Report 1998/1999." Harvard Business School Supplement 700-088, January 2000.
  • 2013
  • Teaching Note

Innovation and Development of China Machine Press in the New Century (TN)

By: F. Warren McFarlan, Ning Jia and Guo Jia
China Machine Press (CMP), founded in 1952, is a leading multi-field, multi-discipline and multimedia publishing group in China with large scale, comprehensive and specialized business that integrates paper media, audiovisual media and online media, and combines... View Details
Keywords: General Management; Organizational Structure; Strategy; China; China
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McFarlan, F. Warren, Ning Jia, and Guo Jia. "Innovation and Development of China Machine Press in the New Century (TN)." Tsinghua University Teaching Note, 2013.
  • August 1997
  • Case

European Bank for Reconstruction and Development in 1997, The

By: Hugo Uyterhoeven, Michael Y. Yoshino and Carin-Isabel Knoop
Keywords: Banking Industry; Europe
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Uyterhoeven, Hugo, Michael Y. Yoshino, and Carin-Isabel Knoop. "European Bank for Reconstruction and Development in 1997, The." Harvard Business School Case 398-032, August 1997.
  • September 2006 (Revised February 2010)
  • Supplement

Airbus vs. Boeing (C): Developments from 1996 to 1999

By: Ramon Casadesus-Masanell, Erich Alexander Voigt and Jordan Mitchell
Keywords: Business Model; Air Transportation Industry
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Casadesus-Masanell, Ramon, Erich Alexander Voigt, and Jordan Mitchell. "Airbus vs. Boeing (C): Developments from 1996 to 1999." Harvard Business School Supplement 707-449, September 2006. (Revised February 2010.)
  • July 1987 (Revised November 1989)
  • Teaching Note

Lotus Development Corp. Channel Choice: Direct vs. Distribution, Teaching Note

By: V. Kasturi Rangan
Teaching Note for (9-587-078). View Details
Keywords: Software; Information Technology Industry
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Rangan, V. Kasturi. "Lotus Development Corp. Channel Choice: Direct vs. Distribution, Teaching Note." Harvard Business School Teaching Note 588-007, July 1987. (Revised November 1989.)
  • April 2012
  • Article

Broadening Focus: Spillovers, Complementarities and Specialization in the Hospital Industry

By: Jonathan R. Clark and Robert S. Huckman
The long-standing argument that focused operations outperform others stands in contrast to claims about the benefits of broader operational scope. The performance benefits of focus are typically attributed to reduced complexity, lower uncertainty, and the development... View Details
Keywords: Performance Capacity; Operations; Advertising; Production; Corporate Strategy; Relationships; Medical Specialties; Complexity; Risk and Uncertainty; Experience and Expertise; Diversification; Quality; Health Industry
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Clark, Jonathan R., and Robert S. Huckman. "Broadening Focus: Spillovers, Complementarities and Specialization in the Hospital Industry." Management Science 58, no. 4 (April 2012): 708–722.
  • June 2012
  • Case

Microsoft IT India

By: Willy C. Shih, Margaret Pierson, Alexander Down, William Gustave Jair-Shemuel Jurist, Diego Medicina and Helen Wang
Raj Biyani faced tough challenges managing Microsoft IT India: leading a remote development organization in which key decisions were made in Redmond, and managing an organization that was perceived as less strategic than its sister Microsoft India Development Center... View Details
Keywords: Organizational Development; Cross-functional Management; Foreign Subsidiaries; Strategy Alignment; Organizational Behavior; Indian Software Development; Global Distributed R&D; Software Industry; Organizational Structure; Research and Development; Operations; Leadership; Globalized Firms and Management; Business Subsidiaries; Information Technology; Applications and Software; Technology Industry; India
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Shih, Willy C., Margaret Pierson, Alexander Down, William Gustave Jair-Shemuel Jurist, Diego Medicina, and Helen Wang. "Microsoft IT India ." Harvard Business School Case 612-078, June 2012.
  • 2000
  • Other Unpublished Work

Career Concerns and Staged Investment: Evidence from the Venture Capital Industry

By: Malcolm Baker
I develop a model in which career concerns lead to inefficient reinvestment decisions. Managers have incentives to inflate interim returns by continuing bad projects and delaying write-offs. In the venture capital industry, the syndication of follow-on investments can... View Details
Keywords: Performance Efficiency; Valuation; Venture Capital; Investment; Decisions; Motivation and Incentives; Quality
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Baker, Malcolm. "Career Concerns and Staged Investment: Evidence from the Venture Capital Industry." 2000. (First draft in 2000.)
  • June 2002 (Revised November 2005)
  • Case

Life, Death, and Property Rights: The Pharmaceutical Industry Faces AIDS in Africa

By: Debora L. Spar
In the final years of the 20th century, the world was hit by a plague of epidemic proportions--AIDS, a life-threatening disease that remained stubbornly immune to any cure or vaccine. In the developed nations of the West, AIDS was slowly brought under control through a... View Details
Keywords: Patents; Health Pandemics; Corporate Social Responsibility and Impact; Pharmaceutical Industry; Africa
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Spar, Debora L., and Nick Bartlett. "Life, Death, and Property Rights: The Pharmaceutical Industry Faces AIDS in Africa." Harvard Business School Case 702-049, June 2002. (Revised November 2005.)
  • 25 Sep 2000
  • Research & Ideas

More Than the Sum of Its Parts: The Impact of Modularity on the Computer Industry

The computer age began some six decades ago with general-purpose machines with Star Wars-like names such as ENIAC and EDVAC. They were powered by vacuum tubes, big enough to fill an entire room, and developed by mathematicians under the... View Details
Keywords: by Staff; Computer; Consumer Products; Technology
  • 2010
  • Working Paper

The Influence of Prior Industry Affiliation on Framing in Nascent Industries: The Evolution of Digital Cameras

New industries sparked by technological change are characterized by high uncertainty. In this paper we explore how a firm's conceptualization of products in this context, as reflected by product feature choices, is influenced by prior industry affiliation. We study... View Details
Keywords: Experience and Expertise; Technological Innovation; Product Launch; Market Entry and Exit; Industry Growth; Product Development; Behavior; Competitive Strategy; Electronics Industry
Citation
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Benner, Mary J., and Mary Tripsas. "The Influence of Prior Industry Affiliation on Framing in Nascent Industries: The Evolution of Digital Cameras." Harvard Business School Working Paper, No. 11-007, July 2010. (Revised December 2010.)
  • 2013
  • Working Paper

Entrepreneurs, Firms and Global Wealth since 1850

By: G. Jones
This working paper integrates the role of entrepreneurship and firms into debates on why Asia, Latin America and Africa were slow to catch up with the West following the Industrial Revolution and the advent of modern economic growth. It argues that the currently... View Details
Keywords: Institutional Change; Political Economy; Emerging Economies; Developing Countries; Industrial Development; Culture; Human Capital; Economic History; History; Wealth and Poverty; Business History; Emerging Markets; Globalization; Developing Countries and Economies; Manufacturing Industry; Manufacturing Industry; Manufacturing Industry; Latin America; Asia; North and Central America; Africa; South America; Europe
Citation
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Jones, G. "Entrepreneurs, Firms and Global Wealth since 1850." Harvard Business School Working Paper, No. 13-076, March 2013.
  • July 1992 (Revised June 1993)
  • Case

Pioneer Hi-Bred International, Inc.: IT Support of Corn Research and Development

By: Richard L. Nolan, Donna B. Stoddard and Sorin A. Bodea
Keywords: Plant-Based Agribusiness; Research and Development; Information Technology; Agriculture and Agribusiness Industry
Citation
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Nolan, Richard L., Donna B. Stoddard, and Sorin A. Bodea. "Pioneer Hi-Bred International, Inc.: IT Support of Corn Research and Development." Harvard Business School Case 193-010, July 1992. (Revised June 1993.)
  • September 2018
  • Article

An Exploratory Study of Product Development in Emerging Economies: Evidence from Medical Device Testing in India

By: Budhaditya Gupta and Stefan Thomke
Recent research has studied innovation in emerging economies. However, microlevel product development processes in these economies are relatively unexplored, and the mechanisms by which the emerging economy context might affect such processes are still unclear. In this... View Details
Keywords: India; Product Development; Emerging Markets; Situation or Environment; Medical Devices and Supplies Industry; India
Citation
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Gupta, Budhaditya, and Stefan Thomke. "An Exploratory Study of Product Development in Emerging Economies: Evidence from Medical Device Testing in India." R&D Management 48, no. 4 (September 2018): 485–501.
  • 11 Feb 2011
  • Working Paper Summaries

Leviathan as a Minority Shareholder: A Study of Equity Purchases by the Brazilian National Development Bank (BNDES), 1995-2003

Keywords: by Sergio G. Lazzarini & Aldo Musacchio
  • June 2009 (Revised June 2009)
  • Case

VidaGas: VillageReach - The Mozambican Foundation for Community Development Joint Venture

This case describes the evolution of a liquid petroleum gas (LPG) distributor start-up, incubated by two not-for-profit NGOs to help improve the vaccine cold chain in Northern Mozambique. These NGOs must face the decision whether and how to sell their participation in... View Details
Keywords: Joint Ventures; Supply Chain; Health Care and Treatment; Investment; Non-Governmental Organizations; Energy Sources; Energy Industry; Energy Industry; Mozambique
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Watson, Noel H., and Santiago Kraiselburd. "VidaGas: VillageReach - The Mozambican Foundation for Community Development Joint Venture." Harvard Business School Case 609-107, June 2009. (Revised June 2009.)
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