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      • November 2022
      • Case

      Ajax Health: A New Model for Medical Technology Innovation

      By: Regina E. Herzlinger and Ben Creo
      This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
      Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Technology Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
      • November 2022
      • Background Note

      The Future of E-Commerce: Lessons from the Livestream Wars in China

      By: Ayelet Israeli, Jeremy Yang and Billy Chan
      This note explores the emerging multi-billion dollar commerce trend of livestream commerce. Livestream commerce is the sale of goods or services directly to consumers via live shows on digital platforms (such as social media or e-commerce platforms). It is a form of... View Details
      Keywords: Retail; Retailing; E-commerce; E-Commerce Strategy; Ecommerce; Channels Of Distribution; Marketing Communication; Livestream Commerce; Marketing; Marketing Channels; Marketing Strategy; Advertising; Brands and Branding; Media; Consumer Behavior; Social Media; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; China; United States; United Kingdom
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      Israeli, Ayelet, Jeremy Yang, and Billy Chan. "The Future of E-Commerce: Lessons from the Livestream Wars in China." Harvard Business School Background Note 523-055, November 2022.
      • November 2022 (Revised December 2024)
      • Case

      Hugging Face (A): Serving AI on a Platform

      By: Shane Greenstein, Daniel Yue, Sarah Gulick and Kerry Herman
      It is fall 2022, and open-source AI model company Hugging Face is considering its three areas of priorities: platform development, supporting the open-source community, and pursuing cutting-edge scientific research. As it expands services for enterprise clients, which... View Details
      Keywords: Community; Open-source; AI and Machine Learning; Product Development; Networks; Service Delivery; Research; Governance; Business and Stakeholder Relations; Information Industry; Technology Industry; United States
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      Greenstein, Shane, Daniel Yue, Sarah Gulick, and Kerry Herman. "Hugging Face (A): Serving AI on a Platform." Harvard Business School Case 623-026, November 2022. (Revised December 2024.)
      • 2022
      • Article

      A Human-Centric Take on Model Monitoring

      By: Murtuza Shergadwala, Himabindu Lakkaraju and Krishnaram Kenthapadi
      Predictive models are increasingly used to make various consequential decisions in high-stakes domains such as healthcare, finance, and policy. It becomes critical to ensure that these models make accurate predictions, are robust to shifts in the data, do not rely on... View Details
      Keywords: AI and Machine Learning; Research and Development; Demand and Consumers
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      Shergadwala, Murtuza, Himabindu Lakkaraju, and Krishnaram Kenthapadi. "A Human-Centric Take on Model Monitoring." Proceedings of the AAAI Conference on Human Computation and Crowdsourcing (HCOMP) 10 (2022): 173–183.
      • November 2022
      • Article

      A Language-Based Method for Assessing Symbolic Boundary Maintenance between Social Groups

      By: Anjali M. Bhatt, Amir Goldberg and Sameer B. Srivastava
      When the social boundaries between groups are breached, the tendency for people to erect and maintain symbolic boundaries intensifies. Drawing on extant perspectives on boundary maintenance, we distinguish between two strategies that people pursue in maintaining... View Details
      Keywords: Culture; Machine Learning; Natural Language Processing; Symbolic Boundaries; Organizations; Boundaries; Social Psychology; Interpersonal Communication; Organizational Culture
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      Bhatt, Anjali M., Amir Goldberg, and Sameer B. Srivastava. "A Language-Based Method for Assessing Symbolic Boundary Maintenance between Social Groups." Sociological Methods & Research 51, no. 4 (November 2022): 1681–1720.
      • October 2022
      • Case

      Pricing at Echosec Systems

      By: Elie Ofek, Marco Bertini, Annelena Lobb and Alexis Lefort
      This case follows the evolution of pricing strategy at Echosec Systems, a Canadian open source intelligence firm. The case provides information on pricing as the company grows and diversifies its product offerings. View Details
      Keywords: Marketing Strategy; Product Positioning; Price; Product Development; Information Industry; Canada; United States
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      Ofek, Elie, Marco Bertini, Annelena Lobb, and Alexis Lefort. "Pricing at Echosec Systems." Harvard Business School Case 523-052, October 2022.
      • October 2022 (Revised June 2025)
      • Case

      Lyra Health: Transforming Mental Health

      By: Rembrand Koning and Nicole Keller
      In January 2022, Lyra Health was deciding between several different alternatives to grow the business. Founded in 2015, Lyra Health was a digital mental health platform that combined technology with human therapists and coaches to deliver high quality mental health... View Details
      Keywords: Mental Health; Health Care and Treatment; Corporate Entrepreneurship; Customer Value and Value Chain; Growth and Development Strategy; Expansion; Health Industry; Technology Industry; San Francisco
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      Koning, Rembrand, and Nicole Keller. "Lyra Health: Transforming Mental Health." Harvard Business School Case 723-365, October 2022. (Revised June 2025.)
      • October 2022
      • Case

      Afrigen Biologics: Vaccines for the Global South

      By: Debora L. Spar and Julia Comeau
      The majority of vaccines used on the continent of Africa (99%) are produced offshore. This makes African nations reliant on the West for major health care needs, a problem which was exacerbated by the COVID-19 pandemic. Afrigen Biologics (in partnership with the WHO)... View Details
      Keywords: Vaccination; Vaccine; mRNA; COVID; COVID-19; Inequity; Hub-and-spoke; Health Care and Treatment; Health Pandemics; Production; Social Issues; Business and Government Relations; South Africa; Africa
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      Spar, Debora L., and Julia Comeau. "Afrigen Biologics: Vaccines for the Global South." Harvard Business School Case 323-030, October 2022.
      • October 2022 (Revised July 2025)
      • Case

      Driving Decarbonization at BMW

      By: Shirley Lu, George Serafeim and Michael W. Toffel
      The case describes BMW’s electrification and decarbonization strategy, and how the company measured carbon emissions throughout the life cycle of its vehicles and used tools like carbon abatement cost curves to evaluate decarbonization opportunities. In mid-2022,... View Details
      Keywords: Decarbonization; Climate Change; Environment; Sustainability; Carbon Accounting; Carbon; Carbon Abatement; Electric Vehicles; Automobiles; Transportation; Environmental Accounting; Environmental Management; Environmental Sustainability; Accounting; Strategy; Technological Innovation; Supply Chain; Business and Stakeholder Relations; Transportation Industry; Auto Industry; Battery Industry; Germany; China; United States; Europe
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      Lu, Shirley, George Serafeim, and Michael W. Toffel. "Driving Decarbonization at BMW." Harvard Business School Case 123-008, October 2022. (Revised July 2025.)
      • October 2022 (Revised September 2024)
      • Case

      mPharma: Scaling Access to Affordable Primary Care in Africa

      By: Regina E. Herzlinger and Ben Creo
      mPharma hopes to scale up to create the largest pan-African healthcare company ever to provide much-needed primary care in retail pharmacies; a reliable, fairly priced supply of drugs; and micro-insurance for drugs. They must prioritize launching a telemedicine... View Details
      Keywords: Africa; Pharmaceutical Companies; Pharmacy Benefit Manager; Health Care; Health Care And Treatment; Health Care Costs; Health Care Delivery; Health Care Entrepreneurship; Telehealth; Health Equity; Corporate Strategy; Social Entrepreneurship; Equity; Growth and Development Strategy; Expansion; Product Launch; Customer Value and Value Chain; Social Enterprise; Multinational Firms and Management; Pharmaceutical Industry; Health Industry; Africa
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      Herzlinger, Regina E., and Ben Creo. "mPharma: Scaling Access to Affordable Primary Care in Africa." Harvard Business School Case 323-033, October 2022. (Revised September 2024.)
      • October 2022
      • Case

      Beam Dental (A)

      By: Rembrand Koning and Alicia Dadlani
      In May 2014, Alex Frommeyer, cofounder and CEO of Kentucky-based Beam Dental, a seed-stage startup that developed connected toothbrushes that tracked brushing habits, needed to decide which strategy to pitch to a venture capital firm. The first pitch deck played to the... View Details
      Keywords: Business Startups; Business Strategy; Entrepreneurship; Financing and Loans; Presentations; Product Development; Insurance Industry; United States; Kentucky; Ohio
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      Koning, Rembrand, and Alicia Dadlani. "Beam Dental (A)." Harvard Business School Case 723-355, October 2022.
      • October 2022 (Revised September 2024)
      • Case

      Podimetrics: Next Steps for Diabetes Cases

      By: Regina E. Herzlinger and Ben Creo
      Podimetrics, a virtual care management company treating adults with acute diabetes, sat at the intersection of medical device technology, digital health, and health services. Its SmartMat had demonstrated that it could help prevent amputations and that people with... View Details
      Keywords: Health Care; Health Care Delivery; Health Care Entrepreneurship; Health Care Outcomes; Diabetes; Chronic Disease; Chronic Illness; Health Care and Treatment; Health Disorders; Medical Specialties; Technological Innovation; Innovation Strategy; Product Development; Business Model; Customer Focus and Relationships; Medical Devices and Supplies Industry; Health Industry
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      Herzlinger, Regina E., and Ben Creo. "Podimetrics: Next Steps for Diabetes Cases." Harvard Business School Case 323-015, October 2022. (Revised September 2024.)
      • September 2022 (Revised November 2023)
      • Case

      Wordle

      By: Karen G. Mills, Christina Wallace, Ebehi Iyoha, Gabriella Elanbeck and Morgane Herculano
      After sourdough bread, countertop chive gardens, and vaccine selfies came a pandemic-era trend that everyone seemed to be in on: one daily chance to guess a five-letter word and crow about your success on social media via little green and yellow squares. From a... View Details
      Keywords: Games; Innovation; General Management; Mergers and Acquisitions; Trends; Entrepreneurship; Bids and Bidding; Consumer Behavior; Entertainment and Recreation Industry; Technology Industry
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      Mills, Karen G., Christina Wallace, Ebehi Iyoha, Gabriella Elanbeck, and Morgane Herculano. "Wordle." Harvard Business School Case 323-032, September 2022. (Revised November 2023.)
      • September 2022 (Revised September 2024)
      • Case

      Esas Group: Investing Together, Staying Together

      By: Christina R. Wing and Alpana Thapar
      This case opens in June 2022, after Esas Group, one of Turkey’s largest family-owned investment firms, implements a series of changes to professionalize the business and help transition family members from operators to responsible investors. In December 2019, the Group... View Details
      Keywords: Family Business; Transition; Business or Company Management; Organizational Structure; Governing and Advisory Boards; Governance; Financial Services Industry; Turkey
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      Wing, Christina R., and Alpana Thapar. "Esas Group: Investing Together, Staying Together." Harvard Business School Case 623-027, September 2022. (Revised September 2024.)
      • September 2022
      • Case

      ROI vs. ROI: The Grupo Baobá Family Office

      By: Lauren Cohen, Hao Gao, Jiawei Ye and Grace Headinger
      Fernando Scodro, a third-generation member of his family, mulled over the next step in integrating an ESG strategy into his family office’s investment portfolio. While his family office, Grupo Baobá, had made excellent progress in incorporating his family’s values into... View Details
      Keywords: Impact Investing; ESG; Green Building; Family; Partnership; Latin America; Brazil; Buildings and Facilities; Green Buildings; Family Business; Family and Family Relationships; Financial Management; Partners and Partnerships; Financial Services Industry; Brazil; Latin America
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      Cohen, Lauren, Hao Gao, Jiawei Ye, and Grace Headinger. "ROI vs. ROI: The Grupo Baobá Family Office." Harvard Business School Case 223-018, September 2022.
      • September 2022
      • Article

      Find and Replace: R&D Investment Following the Erosion of Existing Products

      By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor
      How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first... View Details
      Keywords: R&D Investments; Drug Development; Product Shocks; M&A; Biopharmaceutical Industry; FDA; System Shocks; Research and Development; Investment; Decision Making; Pharmaceutical Industry
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      Krieger, Joshua L., Xuelin Li, and Richard T. Thakor. "Find and Replace: R&D Investment Following the Erosion of Existing Products." Management Science 68, no. 9 (September 2022): 6552–6571.
      • August 2022 (Revised October 2023)
      • Case

      Bajaj Finance: Building an Omnipresent Financial Services Firm

      By: Das Narayandas and Rachna Tahilyani
      Bajaj Finance, India’s largest consumer finance firm with $20.9 billion of assets across 50.5 million customers, is on a journey to transform itself from a traditional firm that sells loans and other financial products through brick-and-mortar outlets to an omnipresent... View Details
      Keywords: Financial Institutions; Transformation; Financial Instruments; Customer Satisfaction; Internet and the Web; Customer Focus and Relationships; India
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      Narayandas, Das, and Rachna Tahilyani. "Bajaj Finance: Building an Omnipresent Financial Services Firm." Harvard Business School Case 523-040, August 2022. (Revised October 2023.)
      • August 2022
      • Case

      Southwick Social Ventures

      By: Henry McGee, Mel Martin and Amy Klopfenstein
      In 2021, the HBS Impact Investment Fund student team had found a promising potential investment in Southwick Social Ventures (SSV), a worker and management-owned trouser manufacturer. With a 100% immigrant workforce, the co-operative was focused on reviving... View Details
      Keywords: Impact Investing; Entrepreneurship; Social Entrepreneurship; Finance; Investment; Goods and Commodities; Manufacturing Industry; United States; Massachusetts
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      McGee, Henry, Mel Martin, and Amy Klopfenstein. "Southwick Social Ventures." Harvard Business School Case 323-011, August 2022.
      • August 2022 (Revised March 2025)
      • Case

      Wasabi Technologies (A)

      By: N. Louis Shipley and Mel Martin
      After launching a successful hot cloud storage company, Founder and CEO David Friend is ready to scale the venture rapidly. Wasabi Technologies had focused primarily on direct sales, but an opportunity to pivot to channel sales was on the horizon. The company’s major... View Details
      Keywords: Direct Sales; Channel Sales; Information Management; Sales; Product Development; Growth and Development Strategy; Business Divisions; Information Technology Industry; United States
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      Shipley, N. Louis, and Mel Martin. "Wasabi Technologies (A)." Harvard Business School Case 823-021, August 2022. (Revised March 2025.)
      • August 2022
      • Case

      Air Wars: Deregulating the U.S. Airline Industry

      By: Tom Nicholas and James Weber
      In the early decades of the twentieth century, the U.S. government assisted in the development of an airline industry by subsidizing the delivery of mail and allowing mail carriers to also fly passengers. Because the government awarded mail routes to the lowest... View Details
      Keywords: Government Regulation; Deregulation; Change Management; Economics; Entrepreneurship; Financial Management; Business History; Human Resources; Compensation and Benefits; Labor; Labor Unions; Leading Change; Leadership Style; Crisis Management; Industry Structures; Operations; Strategy; Adaptation; Competition; Air Transportation; Air Transportation Industry; United States
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      Nicholas, Tom, and James Weber. "Air Wars: Deregulating the U.S. Airline Industry." Harvard Business School Case 823-033, August 2022.
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