Publications

November 2009 (Revised March 2010)
Case

Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon

In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details

Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States

July 2009
Teaching Note

Targanta Therapeutics: Hitting a Moving Target (TN)

By: Arthur A. Daemmrich

Teaching Note for [709002]. View Details

Keywords: Governing Rules, Regulations, and Reforms; Product Development; Business Strategy; Initial Public Offering; Mergers and Acquisitions; Policy; Selection and Staffing; Health Testing and Trials; Resource Allocation; Biotechnology Industry

May 2004
Teaching Note

Monsanto: Technology Cooperation and Small Holder Farmer Projects (TN)

By: James E. Austin and Diana Barrett

Teaching Note to (9-302-068). View Details

Keywords: Biotechnology Industry

November 2001 (Revised December 2002)
Case

Tracking Stocks at Genzyme (A)

By: Malcolm S. Salter

Genzyme, a tracking stock pioneer, has used its innovative capital structure as a way to frame and grow its R&D-intensive business. Facing the question of how best to integrate a new acquisition into its tracking stock structure, Genzyme's top management is forced to... View Details

Keywords: Integration; Value Creation; Motivation and Incentives; Conflict of Interests; Stocks; Capital Structure; Research and Development; Corporate Governance; Biotechnology Industry

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October 2001
Case

TIGR and ILRI: Solving Problems with Genomics

By: Ray A. Goldberg and James M Beagle

Discusses nonprofit institutional leadership applying advances in genetic science to solve health and animal problems in industrial countries and the developing world. View Details

Keywords: Developing Countries and Economies; Health; Technological Innovation; Leading Change; Emerging Markets; Genetics; Non-Governmental Organizations; Technology Adoption; Biotechnology Industry

October 2001 (Revised June 2002)
Case

Centagenetix (A): Building a Business Model for Genetic Longevity

Describes a start-up company seeking to exploit population genetic data from long-lived, healthy people. The company must address legal, financial, ethical, and personal issues among its team to launch the company. View Details

Keywords: Ethics; Genetics; Business Startups; Biotechnology Industry

April 2001 (Revised January 2003)
Case

Robert Shapiro and Monsanto

Traces Monsanto's efforts to become a global biotech powerhouse under Shapiro's leadership. Examines how his crusade to save the world through genetic modification foundered. View Details

Keywords: Genetics; Supply Chain Management; Alliances; Global Strategy; Cross-Cultural and Cross-Border Issues; Biotechnology Industry

December 2000
Case

Paradigm Genetics: The Industrialization of Genomics

By: Ray A. Goldberg, Carin-Isabel Knoop and Laure Mougeot Stroock

Keywords: Genetics; Biotechnology Industry

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November 1999
Case

Seminis Inc.

By: Ray A. Goldberg, Jonathan West, Carin-Isabel Knoop and David Benedict Pearcy

Seminis became the world leader in vegetable seeds through a series of acquisitions. This case describes the Seminis strategy toward capturing value, biotechnology, and international operations. View Details

Keywords: Business Earnings; Acquisition; Profit; Global Strategy; Corporate Strategy; Valuation; Value Creation; Biotechnology Industry

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August 1996 (Revised May 1997)
Case

Delta & Pine Land: Measuring the Value of Transgenic Cotton

By: Ray A. Goldberg and Charlotte A. Tasker

Discusses the joint venture between two companies with different capabilities: 1) technology provider and 2) transportation agent. Discusses how to capture value from joint venture and biotechnology: 1) who are winners and who are losers; 2) how much value can/should... View Details

Keywords: Agribusiness; Joint Ventures; Marketing Strategy; Supply Chain Management; Performance Consistency; Information Technology; Transportation; Valuation; Biotechnology Industry

November 1995 (Revised February 1996)
Case

Monsanto Company: The Coming of Age of Bio-Technology

By: Ray A. Goldberg and Thomas N. Urban Jr

Monsanto has one product, Roundup, accounting for 30% of company net income and is going off patent. How should the company position itself and its products in the future? View Details

Keywords: Patents; Product Positioning; Strategic Planning; System Shocks; Biotechnology Industry

November 1978 (Revised October 1989)
Case

Amicon Corp. (B)

Details the negotiation between Amicon and three potential licensees, Jackson, Maynard-Smith and Behrstein. View Details

Keywords: Technology; Patents; Negotiation Process; Negotiation Participants; Health Care and Treatment; Biotechnology Industry

October 2020 (Revised April 2022)
Case

When Institutions Fail: HIV/AIDS in the 1980s

By: Tom Nicholas and Christian Godwin

During the early 1980s, young gay men in urban centers such as San Francisco and New York City began contracting a mysterious illness that would come to be known as HIV/AIDS. A diagnosis meant almost certain death, with a less than 1% survival rate. Conflicting... View Details

January 2016 (Revised February 2016)
Course Overview Note

The Sustainable Core: Operations Management

By: Michael W. Toffel and L. Beril Toktay

This note is designed to help faculty embed environmental sustainability content into their core Operations Management course at the MBA or undergraduate level. It can also be used to identify cases with environmental content that can be used in operations electives... View Details

Keywords: Environmental Management; Operations Management; Sustainable Operations; Environmental Regulation; Operations; Supply Chain; Supply Chain Management; Agriculture and Agribusiness Industry; Biotechnology Industry; Food and Beverage Industry; Construction Industry; Forest Products Industry; Retail Industry