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  • 2018
  • Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details
Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly
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  • 2024
  • Working Paper

Does the Case for Private Equity Still Hold?

By: Nori Gerardo Lietz and Philipp Chvanov
Private Equity (“PE”) received a 10-fold increase in capital flows since the Great Financial Crisis (“GFC”) Investors sought higher nominal returns relative to those they could obtain in the public capital markets. This paper questions the fundamental assumptions... View Details
Keywords: Private Equity; Investment Return; Investment Portfolio; Financial Markets
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  • 14 Nov 2005
  • Research & Ideas

How Can Start Ups Grow?

those one-out-of-ten firms grow into successful, sustained enterprises? Assistant professor Mukti Khaire believes that small companies can grow by developing intangible social resources such as legitimacy,... View Details
Keywords: by Sarah Jane Gilbert; Advertising
  • 07 Jan 2015
  • Research & Ideas

The Quest for Better Layoffs

were convinced that their classmates had no idea what it would be like to be in a small town in New England, and to no longer have a source of employment." “We want to change the way layoffs are done” Those emails have led to a... View Details
Keywords: by Carmen Nobel; Manufacturing
  • 14 Nov 2023
  • Research & Ideas

The Network Effect: Why Companies Should Care About Employees’ LinkedIn Connections

In today’s high-tech economy, it’s not just quant skills and R&D know-how that confer competitive advantage. Relationships still matter—maybe more than ever, as social media turbocharges old-fashioned networking. A new study mapped LinkedIn connections among View Details
Keywords: by Ben Rand
  • 16 Apr 2001
  • Research & Ideas

Making the Most of Government Upheaval

privatization have created unprecedented opportunities for firms of all sizes and varieties to compete in larger markets than ever before. In the process, a handful of global organizations have risen to replace formerly state-owned... View Details
Keywords: by Nancy O. Perry
  • 17 Jul 2012
  • First Look

First Look: July 17

article: http://hbr.org/2012/07/a-better-way-to-tax-us-businesses/ar/1 How Firms Respond to Mandatory Information Disclosure Authors:Anil Doshi, Glen W.S. Dowell, and Michael W. Toffel Publication:Strategic Management Journal... View Details
Keywords: Sean Silverthorne
  • 07 Dec 2009
  • Research & Ideas

Government’s Positive Role in Kick-Starting Entrepreneurship

Silverthorne: Why is this book right for the times? Josh Lerner: There are two sets of events that make this book particularly timely. First, there is a keen awareness on the part of many governments of the need for "green shoots," high-potential View Details
Keywords: by Sean Silverthorne; Technology
  • 22 Jan 2008
  • Research & Ideas

New Challenges in Leading Professional Services

small ways and acknowledge the contribution of the largest portion of their workforce. Solid citizens don't demand much but the return will be enormous in terms of renewed commitment, output, and overall View Details
Keywords: by Sean Silverthorne; Consulting; Accounting; Legal Services
  • 26 Mar 2013
  • First Look

First Look: March 26

ones. Findings: Our key counterintuitive finding is that Japanese and American founders of entrepreneurial firms are more similar than is often suggested. We first find that in both Japan and the U.S., achievement motivation is positively... View Details
Keywords: Sean Silverthorne
  • 09 Apr 2019
  • First Look

New Research and Ideas, April 9, 2019

April 4, 2019 Palgrave Macmillan Fintech, Small Business & the American Dream: How Technology Is Transforming Lending and Shaping a New Era of Small Business Opportunity By: Mills, Karen G.... View Details
Keywords: Dina Gerdeman
  • 2024
  • Working Paper

Do Collusive Norms Maximize Profits? Evidence From a Vegetable Market Experiment in India

By: Abhijit Banerjee, Greg Fischer, Dean Karlan, Matt Lowe and Benjamin N. Roth
Social norms have been shown to facilitate anti-competitive behavior in decentralized markets. We demonstrate that these norms can also reduce aggregate profits. First, we present descriptive evidence of competition-suppressing norms in Kolkata vegetable markets.... View Details
Keywords: Collusion; Competition; Market Entry and Exit; Small Business; Microeconomics; Kolkata
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  • 18 Dec 2018
  • First Look

New Research and Ideas, December 18, 2018

the threshold for research and development (R&D) investment in an economically viable product. Further, the small size of patient populations for orphan drugs, together with the increasing prevalence of biologics among orphan drugs,... View Details
Keywords: Dina Gerdeman
  • 26 Nov 2013
  • First Look

First Look: November 26

find that GPs are associated with higher expected acquisition premiums and that this association is at least partly due to the effect of GPs on executive incentives. However, we also find that firms that adopt GPs experience negative... View Details
Keywords: Sean Silverthorne
  • August 2003 (Revised August 2024)
  • Case

Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment

By: Regina E. Herzlinger and John McDonough
Many health care innovations appear successful; but fail. This is the first case in the Innovating Health Care course that investigates how to create successful health care innovations. It is part of the first module in the course. This module focuses on how to... View Details
Keywords: Three Pillars; Industry Analysis; Health Care and Treatment; Innovation and Invention; Innovation and Management; Medical Specialties; Health Industry
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  • 11 Sep 2017
  • Research & Ideas

Why Employers Favor Men

likely to advance to the top of their fields. Women make up just 4.2 percent of CEOs at S&P 500 firms and 19.2 percent of board members. "This discrimination does not appear to be driven by gender-specific stereotypes or animus" The... View Details
Keywords: by Dina Gerdeman
  • 09 Feb 2007
  • Working Paper Summaries

Do Corporate Social Responsibility Ratings Predict Corporate Social Performance?

Keywords: by Aaron K. Chatterji, David I. Levine & Michael W. Toffel
  • 2019
  • Article

Industrie-Holding: Creating a Community of Interest among Swiss 'Multinationals'

By: Sabine Pitteloud
This article focuses on the genesis and evolution of Industrie-Holding, a federation of Swiss multinationals, from 1942 onwards. Thanks to recent donations from the Alusuisse and Hero archives, historians now have access to the minutes of the Industrie-Holding... View Details
Keywords: Business ＆ Government Relations; Multinationals; Lobbying; Business and Government Relations; Multinational Firms and Management; Switzerland
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  • 20 Mar 2019
  • Working Paper Summaries

In the Shadows? Informal Enterprise in Non-Democracies

Keywords: by Kristin Fabbe, Allison Spencer Hartnett, and Steve L. Monroe
  • 04 Dec 2006
  • Research & Ideas

The Money Connection—Understanding VC Networks

seeking investment at a later stage of a company's financing, when they enjoy geographic proximity to the start-up in question, and when they are a specialist in the start-up's industry. Under these low-risk circumstances, a firm starts... View Details
Keywords: by Julia Hanna; Financial Services

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