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September 2024
Article

Standing on the Shoulders of Science

By: Joshua Lev Krieger, Monika Schnitzer and Martin Watzinger

Today’s innovations rely on scientific discoveries of the past, yet only some corporate R&D builds directly on scientific output. In this paper, we analyze U.S. patents to investigate how firms generate value by building on prior art “closer” to science. We show... View Details

Keywords: Patent Novelty; Value Capture; Science; Patents; Valuation; Research and Development

September 2024
Article

The Human Side of the Future of Work: Understanding the Role People Play in Shaping a Changing World

By: Jochen I. Menges, Lauren C. Howe, Erika Hall, Jon M. Jachimowicz, Sharon K. Parker, Riki Takeuchi, Abhijeet K. Vadera, Ashley Whillans and Susan K. Cohen

For as long as there has been work, there has been a “future of work,” through humans’ ingenuity and drive to get things done easier, faster, and better. With the industrial revolution, efforts to shape a better future of work were dominated by improvements in... View Details

Keywords: Change; Labor

2024
Working Paper

The Operational Impact of Customer Location in On-Demand Services

By: Natalie Epstein, Santiago Gallino and Antonio Moreno

The rapid growth of on-demand delivery services, particularly in the food and grocery sectors, has driven the expansion of hyperlocal fulfillment centers (FCs). This paper uses data from an on-demand grocery delivery platform in Latin America to assess how customer... View Details

Keywords: Consumer Behavior; Logistics; Geographic Location; Service Delivery; Quality; Retail Industry; Latin America

2024
Working Paper

What Do Bank Trading Desks Do?

By: Lina Lu and Jonathan Wallen

Bank trading desks earn profits from intermediating customer trading volume. Across a broad set of asset markets, we document that the trading desks of large U.S. dealer banks behave as financial intermediaries that profit from toll-taking as in Duffie et al. (2005).... View Details

Keywords: Banks and Banking; Profit; Financial Markets

August 2024 (Revised February 2025)
Case

Novo Nordisk Foundation

By: Debora L. Spar and Julia M. Comeau

In 2024, Novo Nordisk A/S was one of the most profitable firms in the world, thanks largely to just two GLP-1-based drugs, Ozempic and Wegovy. Unusually, this incredibly profitable firm was controlled not by individual private shareholders, but by a non-profit... View Details

Keywords: Pharmaceutical Companies; Diabetes; Obesity; Foundation; Non-profit Management; Profit; Corporate Governance; Business or Company Management; Corporate Social Responsibility and Impact; Expansion; Philanthropy and Charitable Giving; Nonprofit Organizations; Pharmaceutical Industry; Denmark; Europe

August 2024
Background Note

The Five Pillars That Drive the Success or Failure of Healthcare and Life Sciences Innovations

By: Regina E. Herzlinger

August 2024
Case

Cristina Ventura: The Career of a Catalyst

By: Linda A. Hill, Allison J. Wigen and Ruth Page

This multimedia case follows the career of Chief Catalyst Officer for the Lane Crawford Joyce Group (LCJG), Cristina Ventura. After beginning her career in luxury in Europe and Asia, Ventura was recruited in 2011 to open Apple’s flagship stores in Hong Kong and South... View Details

Keywords: Innovation Leadership; Innovation Strategy; Technological Innovation; Leadership Style; Leading Change; Entrepreneurship; Luxury; Family Business; Personal Development and Career; Fashion Industry; Retail Industry; Technology Industry; Asia; China; Hong Kong

August 2024 (Revised December 2024)
Case

Influencer-Led Brand Building: Hairitage and the McKnights

By: William R. Kerr, Daniel O'Connor and James Palano

Longtime hairstyle influencer Mindy McKnight had been building her “Cute Girls Hairstyles” audience across numerous online platforms for nearly two decades. Brand incubator Maesa took an innovative approach to producing successful brands: identifying white space in the... View Details

Keywords: Business Model; Customer Focus and Relationships; Brands and Branding; Product Launch; Product Development; Partners and Partnerships; Power and Influence; Beauty and Cosmetics Industry; Consumer Products Industry

August 2024
Case

Sky Therapeutics: Innovating in Digital Therapeutics

By: Satish Tadikonda, Olivia Reszczynski and William Marks

Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still... View Details

Keywords: Business Startups; Entrepreneurship; Mission and Purpose; Health Care and Treatment; Technological Innovation; Business Strategy; Health Industry; Technology Industry

2024
Case

EPCorp: What Story Does the Data Tell?

By: Jacob M. Cook

In EPCorp: What Story Does the Data Tell?, the Quick Case begins with Shivani Bahl researching problems with her company's website so that she can begin to analyze which option would help EPCorp most: selling all its products on Amazon or improving its own data... View Details

Keywords: Distribution Channels; E-commerce; Analytics and Data Science; Decision Making

August 2024
Case

Iogen: Decarbonizing Hard-to-Abate Sectors

By: George Serafeim, Charlotte Foody and John Mulliken

Brian Foody, CEO of Iogen Corporation, was an early leader in advanced biofuels, developing a range of technologies to transform agricultural waste into transportation fuel. With $100 million in revenue and 350 patents across various biofuel technologies, Iogen was... View Details

Keywords: Technology; Biofuel; Market Attractiveness; Decarbonization; Technological Innovation; Climate Change; Energy; Environmental Sustainability; Transformation; Market Entry and Exit; Strategy; Energy Industry; United States; United Kingdom

20 Aug 2024
Interview

Angel City Football Club: A New Business Model for Women’s Sports

By: Jeffrey F. Rayport, Brian Kenny and Nicole Tempest Keller

Angel City Football Club (ACFC) was founded in 2020 by venture capitalist Kara Nortman, entrepreneur Julie Uhrman, and actor and activist Natalie Portman. As outsiders to professional sports, the all-female founding team had rewritten the playbook for how to build a... View Details

Keywords: Brands and Branding; Gender; Franchise Ownership; Business Model; Sports Industry

August 2024
Case

Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic

By: Susanna Gallani, Karen L. Sedatole and Sarah Mehta

Set in March 2024, this case is about CWC Alliance (CWC), a nonprofit working to prevent opioid addiction in the U.S. Founder Cammie Wolf Rice launched CWC in 2018 after her son, Christopher Wolf, died of a heroin overdose. Wolf’s dependence on opioids stemmed from a... View Details

Keywords: Health Care and Treatment; Innovation and Invention; Jobs and Positions; Nonprofit Organizations; Expansion; Growth and Development Strategy; Service Delivery; Mission and Purpose; Health Industry; United States; Georgia (state, US); Atlanta

August 2024 (Revised October 2024)
Case

Discerene Group: Long-Term Public-Markets Investing

By: Luis M. Viceira and Brent Schwarz

This case discusses active investing based on fundamental valuations and price distortions created by market events, and whether contractual terms between investment managers and their investors can help align incentives between long-term investors and active managers.... View Details

Keywords: Financial Strategy; Investment Funds; Valuation; Financial Markets; Financial Services Industry; Connecticut

August 2024 (Revised November 2024)
Case

Mercado Bitcoin: M&A, IPO, or Series B?

By: Raymond Kluender, Emanuele Colonnelli, Sabrina T. Howell and Karina Souza

In April 2021, Brazilian cryptocurrency platform Mercado Bitcoin had to decide how to scale: go public, M&A with a bank, or take a VC big check. In a highly volatile market, Roberto Dagnoni, chairman of the board, viewed the unprecedent crypto momentum as a window of... View Details

August 2024 (Revised January 2025)
Case

Barbie: Reviving a Cultural Icon at Mattel

By: Elie Ofek, Ryann Noe and Sarah Mehta

The 2023 release of the live-action film Barbie, and its accompanying marketing blitz, incited a worldwide Barbie craze. Suddenly Barbie was everywhere, a celebrated icon reinstated at the forefront of cultural conversation. This goodwill stood in contrast to... View Details

Keywords: Brands and Branding; Media; Intellectual Property; Business Strategy; Entertainment; Gender; Public Opinion; Marketing Strategy; Consumer Products Industry; Entertainment and Recreation Industry; Motion Pictures and Video Industry; Retail Industry; United States

August 2024 (Revised November 2024)
Case

Commonwealth Fusion Systems: Born at Scale

By: Joshua Lev Krieger, Jim Matheson, Kyle Myers, Gunnar Trumbull and Richard Vietor

This case study chronicles the journey of Commonwealth Fusion Systems (CFS) on its ambitious mission to commercialize fusion energy and become the world’s leading provider of fusion power plants. Emerging from a “special arrangement” with MIT's Plasma Science and... View Details

Keywords: Nuclear Energy; Innovation; Entrepreneurship; Entrepreneurial Finance; Energy Generation; Commercialization; Science-Based Business; Technological Innovation; Market Entry and Exit; Energy Industry

August 2024 (Revised July 2025)
Case

agilon health

By: Regina E. Herzlinger and Nicholas Samonas

agilon health is part of the Module 1 of the Innovating Healthcare course: How to Evaluate Innovative Health Ventures. agilon health serves two pedagogical purposes: • it faces a difficult evaluation about how to grow the firm • It introduces the students to... View Details

Keywords: Health Industry

2025
Working Paper

Narrative AI and the Human-AI Oversight Paradox in Evaluating Early-Stage Innovations

By: Jacqueline N. Lane, Léonard Boussioux, Charles Ayoubi, Ying Hao Chen, Camila Lin, Rebecca Spens, Pooja Wagh and Pei-Hsin Wang

Do AI-generated narrative explanations enhance human oversight or diminish it? We investigate this question through a field experiment with 228 evaluators screening 48 early-stage innovations under three conditions: human-only, black-box AI recommendations without... View Details

Keywords: Large Language Models; AI and Machine Learning; Innovation and Invention; Decision Making

2024
Working Paper

“If You’re Not There… You’re Not There”: How Art Market Platforms Induce Status Anxiety to Coerce Participation

By: James Riley and Ezra Zuckerman Sivan

This paper, an 18-month ethnographic investigation of international art fairs (IAFs), shows how market platforms can have a coercive effect, inducing sellers (i.e., art galleries) to participate despite ambivalence over their value and anxiety over the process by which... View Details

Keywords: Market Participation; Status and Position; Competition; Demand and Consumers; Fine Arts Industry

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