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  • March 2015 (Revised January 2024)
  • Case

CV Ingenuity (A): How to Evaluate the Commercial Viability of New Health Care Technologies

By: Regina E. Herzlinger and Andrew Otazo
Duke Rohlen (HBS MBA ’01) hoped to win over a prominent venture capital investor for Series B financing of his firm CVI that was creating a drug-eluting balloon (DES) to treat peripheral arterial disease. As a second-mover, Duke felt he was more likely to acquire... View Details
Keywords: CV Ingenuity; CVI; Drug Eluting Balloon; DEB; Drug Eluting Stent; Angioplasty Balloon; FoxHollow; Medical Device; Medical Device Startup; Premarket Approval; PMA; Lutonix; Stellarex; LEVANT; ILLUMENATE; Clinical Trials; Peripheral Arterial Disease; PAD; Healthcare Startups; Covidien; Health Care and Treatment; Health Testing and Trials; Business Startups; Commercialization; Health Industry; Medical Devices and Supplies Industry; United States; Europe
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Herzlinger, Regina E., and Andrew Otazo. "CV Ingenuity (A): How to Evaluate the Commercial Viability of New Health Care Technologies." Harvard Business School Case 315-045, March 2015. (Revised January 2024.)
  • December 2014 (Revised February 2020)
  • Case

Compass Group: The Ascension Health Decision

By: Ryan W. Buell
In 2012, Compass Group (Compass) was on the verge of closing a $2 billion deal with Ascension Health (Ascension), one of the largest healthcare systems in the United States. Under the deal, Compass would provide foodservice management and cleaning services for 86 of... View Details
Keywords: Operations Strategy; Sectorization; Operational Focus; Customer Compatibility; Service Operations; Service Delivery; Operations; Strategy; Customer Focus and Relationships; Service Industry; Health Industry; United States
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Buell, Ryan W. "Compass Group: The Ascension Health Decision." Harvard Business School Case 615-026, December 2014. (Revised February 2020.)
  • 2024
  • Working Paper

HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-007, July 2019. (Revised May 2024.)
  • October 2010 (Revised July 2011)
  • Case

PrimedicProviding Primary Care in Mexico

By: Richard G. Hamermesh, Regina Garcia-Cuellar and Lauren Sarah Margulies
Primedic is a Mexican start-up that aims to deliver affordable primary and preventative healthcare to those at the base of the economic pyramid. The company is about to exhaust its first round of venture capital funding and the business model has yet to gain traction.... View Details
Keywords: Business Model; Business Startups; Developing Countries and Economies; Social Entrepreneurship; Venture Capital; Health Care and Treatment; Social Enterprise; Health Industry; Mexico
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Hamermesh, Richard G., Regina Garcia-Cuellar, and Lauren Sarah Margulies. "PrimedicProviding Primary Care in Mexico." Harvard Business School Case 811-040, October 2010. (Revised July 2011.)
  • November 2021 (Revised December 2021)
  • Case

Praava Health: A New Model for Bangladesh

By: Michael Chu
Launched in Dhaka, Bangladesh, in 2018, Praava Health (‘Praava’) delivered high-quality in-clinic primary and specialist care, backed by its own high quality diagnostic laboratories, imaging and pharmacy. Praava was founder Sylvana Sinha’s response to what she saw as a... View Details
Keywords: Entrepreneurship; Health Care and Treatment; Investment Return; Mobile and Wireless Technology; Business Model; Growth and Development Strategy; Health Industry; Bangladesh; Asia
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Chu, Michael. "Praava Health: A New Model for Bangladesh." Harvard Business School Case 322-067, November 2021. (Revised December 2021.)
  • January 2013 (Revised October 2015)
  • Case

Pittsburgh

By: Eric Werker, Meg Rithmire, Benjamin Kennedy and Andrew Knauer
The case narrates the development of Pittsburgh from the 1940s to 2012. It analyzes the collapse of the steel industry in the early 1980s, the city's subsequent decline, and the city's later re-emergence as a hub for higher education, the tech sector, and the... View Details
Keywords: Google; Population; City Growth; Shale; PNC; Tom Murphy; Luke Ravenstahl; Public-private Partnership; Tax Increment Financing; Brownfields; Renaissance; Industry Clusters; Industry Growth; City; Business and Government Relations; Taxation; Philanthropy and Charitable Giving; Nonprofit Organizations; Higher Education; Technology Industry; Health Industry; Steel Industry; Education Industry; Pittsburgh
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Werker, Eric, Meg Rithmire, Benjamin Kennedy, and Andrew Knauer. "Pittsburgh." Harvard Business School Case 713-035, January 2013. (Revised October 2015.)
  • September 2007 (Revised January 2009)
  • Case

Reading Rehabilitation Hospital: Implementing Patient-Focused Care (A) (Abridged)

By: Roy D. Shapiro
Reading Rehab Hospital has experimented with a popular concept in health care--patient-focused care--intended to increase quality and reduce costs by organizing care delivery around particular diagnoses or "service lines," rather than around the functions or... View Details
Keywords: Health Care and Treatment; Medical Specialties; Quality; Cost; Management Practices and Processes; Business Strategy; Service Delivery; Health Industry
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Shapiro, Roy D. "Reading Rehabilitation Hospital: Implementing Patient-Focused Care (A) (Abridged)." Harvard Business School Case 608-070, September 2007. (Revised January 2009.)
  • March 2014
  • Teaching Note

E-Cigarettes: Marketing Versus Public Health

By: John A. Quelch
Electronic cigarettes (e-cigarettes) were heralded by some as a healthcare game changer, enabling smokers to switch to a new product which carried lower risk of cancer. However, there were concerns about the public health risk of e-cigarettes, particularly the chance... View Details
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Quelch, John A. "E-Cigarettes: Marketing Versus Public Health." Harvard Business School Teaching Note 514-108, March 2014.
  • March 2010 (Revised February 2014)
  • Case

Community Health Workers in Zambia: Incentive Design and Management

By: Nava Ashraf and Natalie Kindred
This case examines the various considerations relevant to selecting and compensating workers in a context where their work involves a pro-social component. This is relevant to not only health care in Zambia, but to NGO and public sector workers who are both motivated... View Details
Keywords: Developing Countries and Economies; Training; Health Care and Treatment; Compensation and Benefits; Recruitment; Selection and Staffing; Mission and Purpose; Non-Governmental Organizations; Motivation and Incentives; Health Industry; Zambia
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Ashraf, Nava, and Natalie Kindred. "Community Health Workers in Zambia: Incentive Design and Management." Harvard Business School Case 910-030, March 2010. (Revised February 2014.) (Request a courtesy copy.)
  • Research Summary

Front-Line Organizational Learning

Dr. Tucker uses operations management and organizational learning theory to understand and improve front-line work processes.  Specifically, she examines the conditions under which the problem solving routines of front-line workers are likely to result in positive... View Details
  • January 2021 (Revised June 2021)
  • Case

Hester Pharmaceuticals (A): A Pricing Dilemma

By: Dante Roscini and John Masko
In August 2019, the leadership of Hester Pharmaceuticals (Hester) had a problem. Italy promised to be a key market for their new breakthrough oncology drug Akrozumab, but for almost two years, its single-payer healthcare system had been unable to agree with Hester on a... View Details
Keywords: Macroeconomics; Trade; Price; Global Range; Global Strategy; Globalized Markets and Industries; Health Care and Treatment; Patents; Monopoly; Negotiation; Business and Government Relations; Risk and Uncertainty; Human Needs; Business Strategy; Commercialization; Pharmaceutical Industry; Italy
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Roscini, Dante, and John Masko. "Hester Pharmaceuticals (A): A Pricing Dilemma." Harvard Business School Case 721-001, January 2021. (Revised June 2021.)
  • May 2010 (Revised May 2011)
  • Case

Kent Thiry: "Mayor" of DaVita

By: William W. George and Natalie Kindred
Kent Thiry, CEO of dialysis provider DaVita, is considering how to integrate employees from recently acquired Gambro Healthcare without damaging DaVita's robust, unconventional internal culture. When Thiry joined DaVita in 1999, breaking an important promise to his... View Details
Keywords: Mergers and Acquisitions; Experience and Expertise; Employee Relationship Management; Leadership Style; Organizational Change and Adaptation; Organizational Culture; Personal Development and Career; Integration; Health Industry
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George, William W., and Natalie Kindred. Kent Thiry: "Mayor" of DaVita. Harvard Business School Case 410-065, May 2010. (Revised May 2011.)
  • September 2007
  • Case

Collaborating to Improve

By: Richard M.J. Bohmer and Ingrid M. Nembhard
Madison Memorial Hospital is deciding between a variety of quality improvement strategies. Highlights quality improvement collaborative—organized programs popularized by the Institute for Healthcare Improvement in which teams from multiple institutions work together to... View Details
Keywords: Health Care and Treatment; Service Delivery; Performance Improvement; Quality; Groups and Teams; Cooperation; Integration; Health Industry
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Bohmer, Richard M.J., and Ingrid M. Nembhard. "Collaborating to Improve." Harvard Business School Case 608-054, September 2007.
  • 18 Oct 2006
  • Research & Ideas

New at the Helm: A Talk with HBS Dean Light

Healthcare Initiative that will draw on the work of our faculty and alumni leaders in the field to create innovative solutions to healthcare problems. In addition, the University plans to break ground next... View Details
Keywords: by Roger Thompson; Education
  • 2021
  • Working Paper

Measuring Employment Impact: Applications and Cases

By: Katie Panella and George Serafeim
Applying the Impact-Weighted Accounts Initiative’s employment impact methodology on eight leading companies, we document wide variability in employment impacts as a percentage of salaries paid, ranging between 59 and 80 percent. We identify opportunities for... View Details
Keywords: Impact Measurement; Employee Compensation; Accounting; Employees; Labor; Well-being; Diversity; Wages; Compensation and Benefits
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Panella, Katie, and George Serafeim. "Measuring Employment Impact: Applications and Cases." Harvard Business School Working Paper, No. 21-082, January 2021. (Revised August 2021.)
  • September 2022
  • Article

Cost of Cardiac Stereotactic Body Radioablation Therapy versus Catheter Ablation for Treatment of Ventricular Tachycardia

By: Chen Wei, Michelle Boeck, Pierre C. Qian, Todd Vivenzio, Zoe Elizee, Jeremy S. Bredfeldt, Robert S. Kaplan, Usha Tedrow, Raymond Mak and Paul C. Zei
Cardiac SBRT is a novel way of treating refractory ventricular tachycardia (VT) that may be less costly than catheter ablation, owing to its noninvasive, outpatient nature. We applied time-driven activity-based costing to both procedures. The direct and total... View Details
Keywords: Health Care and Treatment; Activity Based Costing and Management; Cost; Health Industry
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Wei, Chen, Michelle Boeck, Pierre C. Qian, Todd Vivenzio, Zoe Elizee, Jeremy S. Bredfeldt, Robert S. Kaplan, Usha Tedrow, Raymond Mak, and Paul C. Zei. "Cost of Cardiac Stereotactic Body Radioablation Therapy versus Catheter Ablation for Treatment of Ventricular Tachycardia." Pacing and Clinical Electrophysiology 45, no. 9 (September 2022): 1005–1179.
  • November 2007 (Revised August 2014)
  • Case

D2Hawkeye: Growing the Medical IT Enterprise

By: Robert F. Higgins, Rosie O'Donnell, Sophie LaMontagne and Brent Kazan
In mid-March 2007, Chris Kryder sat in his office and thought about how to best finance his company's growth. Over the previous five years as founder and CEO of D2Hawkeye, a Waltham, Massachusetts-based healthcare analytics company, Kryder had grown the firm from a... View Details
Keywords: Strategy Development; Strategic Positioning; Strategic Vision; Venture Capital; Small Business; Investment; Growth Management; Expansion; Business Growth and Maturation; Decision Choices and Conditions; Financing and Loans; Business Startups; Financial Strategy; Business Strategy; Service Industry; Health Industry; Waltham
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Higgins, Robert F., Rosie O'Donnell, Sophie LaMontagne, and Brent Kazan. "D2Hawkeye: Growing the Medical IT Enterprise." Harvard Business School Case 808-006, November 2007. (Revised August 2014.)
  • August 1998
  • Case

HIMSCORP, Inc.

By: William A. Sahlman, Michael J. Roberts and Laurence E. Katz
Himscorp is an industry consolidation of records storage companies providing management and retrieval services of active medical records to healthcare institutions. Kent Dauten, a former general partner at Madison Dearborn Partners with 15 years of venture capital and... View Details
Keywords: Value Creation; Initial Public Offering; Business Exit or Shutdown; Business Growth and Maturation; Decision Choices and Conditions; Consolidation; Information Industry
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Sahlman, William A., Michael J. Roberts, and Laurence E. Katz. "HIMSCORP, Inc." Harvard Business School Case 899-021, August 1998.
  • January 2018
  • Article

Innovation Incentives and Biomarkers

By: Ariel Dora Stern, Brian M. Alexander and Amitabh Chandra
Previously, we have discussed the importance of economic incentives in shaping markets for precision medicines. Here we consider incentives for biomarker development, including discovery and establishment. Biomarkers can reveal valuable information regarding diagnosis... View Details
Keywords: Health Care and Treatment; Innovation and Invention; Research and Development; Markets
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Stern, Ariel Dora, Brian M. Alexander, and Amitabh Chandra. "Innovation Incentives and Biomarkers." Clinical Pharmacology & Therapeutics 103, no. 1 (January 2018): 34–36.
  • June 2010 (Revised December 2019)
  • Case

Piramal e-Swasthya (A): Attempting Big Changes for Small Places - in India and Beyond

By: Rosabeth M. Kanter and Matthew Bird
Anand Piramal and his team sought to "democratize healthcare" in India through the development of a new service delivery model. If Henry Ford could build and deliver cars to everyone in the United States, Piramal thought, then why can't India deliver healthcare to the... View Details
Keywords: Health Care and Treatment; Service Delivery; Social Entrepreneurship; Change Management; Emerging Markets; Health Industry; India
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Kanter, Rosabeth M., and Matthew Bird. "Piramal e-Swasthya (A): Attempting Big Changes for Small Places - in India and Beyond." Harvard Business School Case 310-134, June 2010. (Revised December 2019.)
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