Publications
Publications
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(5,158)
- Faculty Publications (1,314)
- 2024
- Working Paper
Prozac—Controversial Blockbuster: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes the development of Prozac, a blockbuster drug that transformed
the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we
chronicle the: 1) prior treatments for depression and the research that... View Details
- 2024
- Working Paper
Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for
millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s
development; the initial development of tamoxifen from 1960 to 1973;... View Details
- June 2020
- Supplement
TransDigm in 2017: Congressional Hearing on the DoD Inspector General’s Report (5/15/19)
By: Benjamin C. Esty
This video accompanies the case, “TransDigm in 2017: The Beginning of the End or the End of the Beginning?” View Details
Keywords: Value Capturing; Pricing Strategy; Supplier Power; Buyer Power; Porter's Five Forces; Bargaining Power; Monopoly; Aerospace; Acquisition Strategy; Value Drivers; Ethical Behavior; Regulation; Growth Strategy; Business Ethics; Defense; Procurement; Sustainability; Value Based Health Care; Acquisition; Ethics; Private Equity; Financial Strategy; Growth Management; Performance Evaluation; Business Strategy; Competitive Strategy; Horizontal Integration; Value Creation; Competitive Advantage; Aerospace Industry; Air Transportation Industry; United States
- Article
Sustainability, Business, and Health
By: George Serafeim, Amanda M. Rischbieth and Howard K. Koh
The coronavirus disease 2019 (COVID-19) pandemic has demonstrated that response demands involvement from every sector of society. As a major example, some businesses have stepped up in ways previously unimaginable. Garment companies have repurposed production to face... View Details
- Article
Are Cost Advantages from a Modern Indian Hospital Transferable to the United States?
By: R. S. Kaplan, F. Erhun, V.G. Narayanan, B. Mistry and K. Brayton, et al
We use time-driven activity-based costing to estimate the cost of personnel and space for an elective coronary artery bypass graft (CABG) surgery at two U.S. hospitals, Intermountain and Baylor Heart, and Narayana Health (NH), in India. All three hospitals use modern... View Details
- June 2020
- Article
How Scheduling Can Bias Quality Assessment: Evidence from Food Safety Inspections
By: Maria Ibanez and Michael W. Toffel
Accuracy and consistency are critical for inspections to be an effective, fair, and useful tool for assessing risks, quality, and suppliers—and for making decisions based on those assessments. We examine how inspector schedules could introduce bias that erodes... View Details
- 2020
- Working Paper
How Should U.S. Bank Regulators Respond to the COVID-19 Crisis?
By: Michael Blank, Samuel G. Hanson, Jeremy C. Stein and Adi Sunderam
Drawing on lessons from the 2007–2009 Global Financial Crisis (GFC) and a simple conceptual framework, we examine the response of U.S. bank regulators to the COVID-19 pandemic. We argue that the current regulatory strategy of “watchful waiting”—the same strategy that... View Details
- June 2020
- Article
Overcoming Barriers to Early Disease Intervention
By: H. Hugo Caicedo, Daniel A. Hashimoto, Julio C. Caicedo, Alex Pentland and Gary P. Pisano
It is widely acknowledged that earlier intervention in many disease processes leads to better patient outcomes and lower treatment costs. To date, most efforts at early disease intervention have focused on "primary prevention" which focuses on preventing diseases in... View Details
- Article
The Inpatient Discharge Lounge as a Potential Mechanism to Mitigate Emergency Department Boarding and Crowding
By: Brian Franklin, Sharif Vakili, Robert S. Huckman, Sarah Hosein, Nicholas Falk, Katherine Cheng, Maria Murray, Sheila Harris, Charles A. Morris and Eric Goralnick
Delayed access to inpatient beds for admitted patients contributes significantly to emergency department (ED) boarding and crowding, which have been associated with deleterious patient safety effects. To expedite inpatient bed availability, some hospitals have... View Details
- Article
Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17
By: Karen Shen, Eric Barrette and Leemore S. Dafny
There is abundant literature on efforts to reduce opioid prescriptions and misuse, but comparatively little on the treatment provided to people with opioid use disorder (OUD). Using claims data representing 12–15 million nonelderly adults covered through commercial... View Details
- Article
The Business of Medicine in the Era of COVID-19
By: David M. Cutler, Sayeh Nikpay and Robert S. Huckman
This Viewpoint discusses the shifting landscape of health care financing, regulation, and delivery as a result of the coronavirus pandemic, and discusses regulatory and other changes that need to be in place if telehealth and physician practice and hospital mergers... View Details
- May 21, 2020
- Editorial
Primary Care Is Hurting: Why Aren't Private Insurers Pitching In?
By: Leemore S. Dafny and J. Michael McWilliams
Primary care clinicians are the front line for patients with suspected infection. We rely on them to diagnose, triage, and manage patients with potential or confirmed COVID infections. They are also responsible for keeping non-COVID medical conditions under control... View Details
- Article
Using the Balanced Scorecard for Successful Health Care M&A Integration
By: Robert S. Kaplan
The failure of merged organizations to achieve stated goals is commonplace. In health care, the challenge is exacerbated by the industry’s third-party payer system and multiple stakeholders, especially the physicians in the merging entities. This article describes how... View Details
- May 2020
- Case
Big Boom Beverages: Fight or Flight?
By: Stephen A. Greyser and William Ellet
Four college friends market a beverage that combines ingredients like those in a drink they consumed in college bars. It includes a caffeinated energy drink, malt liquor, and a soft drink flavoring. They launch the business, Big Boom Beverages (BBB), with their own... View Details
- Article
How to End the Plasma Shortage for Coronavirus Patients
Those who have recovered from the virus will donate more blood if given the right incentives. View Details
- May 8, 2020
- Article
Lead Your Team Into a Post-Pandemic World
By: Hubert Joly
The unprecedented COVID-19 pandemic has tested leaders, especially as it relates to how they lead their workers. As the crisis goes on, many that the author has spoken with have begun to frame it around three distinct phases: The Shelter-in-Place Phase, the Re-opening... View Details
- 2020
- Working Paper
Paying It Backward and Forward: Expanding Access to Convalescent Plasma Therapy Through Market Design
By: Scott Duke Kominers, Parag A. Pathak, Tayfun Sönmez and M. Utku Ünver
COVID-19 convalescent plasma (CCP) therapy is currently a leading treatment for COVID-19. At present, there is a shortage of CCP relative to demand. We develop and analyze a model of centralized CCP allocation that incorporates both donation and distribution. In order... View Details
- May 2020 (Revised April 2024)
- Case
Gavi and COVID-19: Pandemic of the Century
By: Tarun Khanna and Sid Misra
Gavi has helped immunize over 760 million children in the world's poorest countries over the past 20 years saving 13 million lives. How should Gavi respond to the need for a vaccine for the worldwide COVID-19 pandemic? View Details
- May 2020
- Article
Identifying Sources of Inefficiency in Health Care
By: Amitabh Chandra and Douglas O. Staiger
In medicine, the reasons for variation in treatment rates across hospitals serving similar patients are not well understood. Some interpret this variation as unwarranted and push standardization of care as a way of reducing allocative inefficiency. However, an... View Details
- May–June 2020
- Article
The Agenda for the Next Generation of Health Care Information Technology
By: Thomas W. Feeley, Zachary Landman and Michael E. Porter
As the diffusion of value-based health care efforts accelerates globally, the need for interoperable information technology systems that support value-based care is essential. Such systems are needed to facilitate dramatic improvements in patient outcomes and... View Details