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January 2009 (Revised July 2009)
Case

Targanta Therapeutics: Hitting a Moving Target

By: Arthur A. Daemmrich

This case explores regulatory, product testing, and business strategy at Targanta Therapeutics, a biotech company preparing its first new drug application to the FDA. In October 2007, Mark Leuchtenberger, president and CEO of Targanta—which has just held a successful... View Details

Keywords: Decision Choices and Conditions; Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Product Development; Business and Government Relations; Business Strategy; Biotechnology Industry; Biotechnology Industry

September 2008
Teaching Note

Chi Mei Optoelectronics (TN)

By: Willy C. Shih

Teaching Note for [608-123]. View Details

Keywords: Diversification; Information Technology; Market Entry and Exit; Standards; Industry Clusters; Supply Chain; Production; Experience and Expertise; Biotechnology Industry; Biotechnology Industry; Taiwan; Asia; Korean Peninsula; China

September 2007 (Revised May 2009)
Case

Syndexa and Technology Transfer at Harvard University

By: Richard G. Hamermesh and David Kiron

Gokhan Hotamisligil is a star researcher at Harvard School of Public Health who has made groundbreaking discoveries linking fat cells, inflammation, and diabetes. He now wants to form a company to commercialize these discoveries. At the same time, Isaac Kohlberg, the... View Details

Keywords: Business Startups; Higher Education; Entrepreneurship; Innovation and Invention; Intellectual Property; Rights; Agreements and Arrangements; Science-Based Business; Commercialization; Biotechnology Industry; Biotechnology Industry

November 2006 (Revised March 2008)
Case

The Harvard Stem Cell Institute

By: William A. Sahlman

Describes a set of issues confronting the leaders of the Harvard Stem Cell Institute, an innovative cross-university effort to accelerate scientific discovery and translation in the domain of stem cells. Covers a wide range of topics, including understanding how... View Details

Keywords: Talent and Talent Management; Higher Education; Entrepreneurship; Collaborative Innovation and Invention; Intellectual Property; Research and Development; Genetics; Biotechnology Industry; Biotechnology Industry; Massachusetts

November 2005 (Revised November 2005)
Case

Massachusetts General Hospital and the Enbrel Royalty

By: David S. Scharfstein and Darren R. Smart

Massachusetts General Hospital is considering selling its royalty interest in Enbrel, Amgen's blockbuster drug for the treatment of rheumatoid arthritis. In assessing whether to sell, and at what price, the hospital must determine its value to a potential buyer as well... View Details

Keywords: Valuation; Price; Investment Return; Capital; Value; Revenue; Health Care and Treatment; Biotechnology Industry; Biotechnology Industry; Massachusetts

March 2005 (Revised August 2005)
Case

Procurement at Betapharm Corp. (A)

Presents a move by Betapharm to centralize procurement and e-sourcing and the many control and incentive issues that arose subsequently. View Details

Keywords: Motivation and Incentives; Governance Controls; Supply Chain Management; Biotechnology Industry; Biotechnology Industry

June 2003 (Revised March 2008)
Case

Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene

By: Regina E. Herzlinger and Marc Aquino

Personalized medicine requires the identification of mutated genes. Schering-Plough's search for the one related to asthma requires finding families with the disease. Examines the industry that helps conduct such research, including contract research organizations. View Details

Keywords: Health Disorders; Research and Development; Genetics; Biotechnology Industry; Biotechnology Industry

November 1998 (Revised October 1999)
Case

E.I. du Pont de Nemours and Company (A)

Du Pont's chief executive must decide what steps to take as his company expands from commodity and specialized chemicals into biotechnology. View Details

Keywords: Technology; Leading Change; Expansion; Biotechnology Industry; Biotechnology Industry

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September 1997 (Revised October 1997)
Case

Bayer AG (A)

By: John A. Quelch

Bayer's senior executives convene in Germany to consider submitting a $1 billion bid that would recover the Bayer brand name and trademark cross in North America, both of which were confiscated by the U.S. government after World War I. The group also sets out to assess... View Details

Keywords: Management Teams; Brands and Branding; War; Communication; Trademarks; Acquisition; Government and Politics; Biotechnology Industry; Biotechnology Industry; Germany; North America; United States

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15 Feb 2000
Research & Ideas

The Right Connections

of IPO Team Ties on Investment Bank Affiliation and IPO Success," which examines how individuals' affiliations can affect the formation of alliances at the firm level. To that end, the researchers pinpointed the biotechnology... View Details

Keywords: by Judith A. Ross

Research Summary

Evolution of firm structure in vertical specialized technology supply chains

By: Willy C. Shih

The global market in many everyday products has been transformed by the internationalization of production. In many industries, semiconductors and electronic products in particular, a sequential mode of production has evolved in which goods are produced... View Details

Keywords: Globalization Of Supply Chain; Globalization; Technological Innovation; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States; Asia; China

Research Summary

Industrial competitiveness in high tech and science-based businesses

By: Willy C. Shih

How do emerging economies develop industrial and technical capabilities that overtake those of advanced economies? Are there some industrial sectors that are especially susceptible to such targeting? What will it take to restore America’s... View Details

Keywords: Technological Innovation; Technology Diffusion; Knowledge Flows; Competitive Advantage; Globalization; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States; China; Asia

September 2019
Case

Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem

By: Willy C. Shih

Vaccines for children has been a long-standing focus for the Bill & Melinda Gates Foundation, and its critical role in public health made its production an important economic and political issue. This case describes the Foundation's investment in a breakthrough vaccine... View Details

Keywords: Vaccine; Production; Supply Chain; Product; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Belgium

June 2010
Teaching Note

Monsanto: Helping Farmers Feed the World (TN)

By: David E. Bell and Mary Louise Shelman

Teaching Note for [510025]. View Details

Keywords: Food; Production; Adoption; Leadership Style; Globalized Markets and Industries; Performance Productivity; Biotechnology Industry; Biotechnology Industry

March 2010 (Revised May 2012)
Case

Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration

By: Karim R. Lakhani and Paul R. Carlile

This case presents the Myelin Repair Foundation's accelerated research collaboration model for drug discovery. It highlights the challenges of building a multi-disciplinary and multi-institutional research collaboration that is attempting to create a treatment for... View Details

Keywords: Research and Development; Intellectual Property; Risk and Uncertainty; Strategic Planning; Collaborative Innovation and Invention; Health Disorders; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry

April 2008
Teaching Note

Viagen: Revolutioning the Livestock Industry (TN)

By: David E. Bell, Mary L. Shelman and Eliot Sherman

Teaching Note for [507021]. View Details

Keywords: Investment; Genetics; Production; Training; Customers; Supply Chain; Business Plan; Commercialization; Information Technology; Performance Efficiency; Governing Rules, Regulations, and Reforms; Industry Structures; Biotechnology Industry; Biotechnology Industry

March 2007
Teaching Note

Monsanto: Realizing Biotech Value in Brazil (TN)

By: David E. Bell and Mary L. Shelman

Keywords: Value; Biotechnology Industry; Biotechnology Industry; Brazil

December 2006 (Revised January 2008)
Case

ViaGen: Revolutionizing the Livestock Industry

By: David E. Bell, Reed Martin and Mary L. Shelman

ViaGen has invested heavily to develop cloning technology for the livestock industry. Cloning has the potential to significantly improve the genetics of livestock, leading to higher quality meat, healthier animals, and more efficient production. Since 2003, the firm... View Details

Keywords: Animal-Based Agribusiness; Business Plan; Governing Rules, Regulations, and Reforms; Marketing Communications; Industry Structures; Business and Government Relations; Genetics; Commercialization; Biotechnology Industry; Biotechnology Industry

September 1990 (Revised November 1990)
Case

DNAP: Looking to the Nineties

By: Ray A. Goldberg

Keywords: Marketing; Product Positioning; Biotechnology Industry; Biotechnology Industry

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May 2025
Supplement

Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)

By: Linda A. Hill and Lydia Begag

This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights how over a decade of cultural and digital evolution positioned GCS to meet unprecedented global challenges. In 2011, Michael Ku became the Vice President of GCS and... View Details

Keywords: Innovation Leadership; Technological Innovation; Leadership Development; Leadership Style; Research and Development; Science-Based Business; Transformation; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States; Asia; Europe; Latin America

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