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Show Results For
- All HBS Web
(6,773)
- People (18)
- News (2,148)
- Research (3,576)
- Events (3)
- Multimedia (212)
- Faculty Publications (2,763)
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- November 2009 (Revised March 2010)
- Case
Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story
By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details
Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States
Hamermesh, Richard G., Raju Kucherlapati, and Rachel Gordon. "Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story." Harvard Business School Case 810-066, November 2009. (Revised March 2010.)
- 04 Mar 2002
- Research & Ideas
Don’t Lose Money With Customers
at the market level, then translate these into strategies at the market segment level. A paper mill's marketing strategy, for instance, might call for selling newsprint to the publishing industry segment and paperboard to the packaging... View Details
Keywords: by Peter K. Jacobs
- 02 Nov 2010
- First Look
First Look: November 2, 2010
a commercial entity (images captured and uploaded from personal cell phone cameras), the news industry landscape became freewheeling and individualistic. The straight-line model of content generator to distributor to reader was gone.... View Details
Keywords: Sean Silverthorne
- January 2007 (Revised January 2007)
- Background Note
Note on the U.S. Food and Drug Administration
By: Robert F. Higgins, Richard G. Hamermesh and Virginia Fuller
Describes the U.S. FDA with particular emphasis on its role in the development of new drugs, biologic products, and medical devices today. Provides context for the drug approval process by describing the FDA's history and organizational structure. View Details
Keywords: Health; Governance Compliance; Policy; Product Development; Government and Politics; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; United States
Higgins, Robert F., Richard G. Hamermesh, and Virginia Fuller. "Note on the U.S. Food and Drug Administration." Harvard Business School Background Note 807-050, January 2007. (Revised January 2007.)
- January 2021
- Supplement
Barbara Krakow Gallery (B): Art and the Pandemic
By: José B. Alvarez and David Lane
Updates (A) case by describing the early impact of the COVID-19 pandemic on the art market, the renaming of the gallery as the Krakow Witkin Gallery, and the response of its partners and staff to the pandemic. View Details
Keywords: Art Market; COVID-19; Arts; Business Model; Change Management; Trends; Communication; Customer Focus and Relationships; Human Resources; Marketing; Distribution Channels; Outcome or Result; Health Pandemics; Fine Arts Industry
Alvarez, José B., and David Lane. "Barbara Krakow Gallery (B): Art and the Pandemic." Harvard Business School Supplement 521-031, January 2021.
- July 1997
- Case
We've Got Rhythm! Medtronic Corporation's Cardiac Pacemaker Business
By: Clayton M. Christensen
Illustrates how a new management team at Medtronic's Cardiac Pacemaker business reversed a steep decline in market share by adopting certain management principles for new product development: clarifying strategy, aggregating project planning, accommodating the number... View Details
Keywords: Management Teams; Innovation Strategy; Innovation and Management; Product Development; Health; Technology; Change Management; Medical Devices and Supplies Industry; United States
Christensen, Clayton M. "We've Got Rhythm! Medtronic Corporation's Cardiac Pacemaker Business." Harvard Business School Case 698-004, July 1997.
- Summer 2020
- Article
Is It Time to Rethink Globalized Supply Chains?: The COVID-19 Pandemic Should Be a Wake-up Call for Managers and Prompt Them to Consider Actions That Will Improve Their Resilience to Future Shocks
By: Willy C. Shih
The COVID-19 pandemic has exposed the complex interdependencies of globalized supply chains. While these global multistage production networks had spread during a relatively benign environment of falling trade barriers and increasing interdependencies among countries,... View Details
Keywords: Supply Chains; Pandemic; Resilience; Supply Chain Management; Supply Chain; Global Range; Health Pandemics; Disruption; System Shocks; Crisis Management; Manufacturing Industry; United States; Asia; Europe; China
Shih, Willy C. "Is It Time to Rethink Globalized Supply Chains? The COVID-19 Pandemic Should Be a Wake-up Call for Managers and Prompt Them to Consider Actions That Will Improve Their Resilience to Future Shocks." MIT Sloan Management Review 61, no. 4 (Summer 2020): 16–18.
- 09 Mar 2020
- Research & Ideas
Warring Algorithms Could Be Driving Up Consumer Prices
that is freely available online—as an input for calculating price changes. In a given industry or category, the most technologically sophisticated company is able to continually undercut its rivals by updating prices more frequently than... View Details
- 03 Mar 2008
- Research & Ideas
Marketing Your Way Through a Recession
Industrial customers prefer to see products and services unbundled and priced separately. Gimmicks are out; reliability, durability, safety, and performance are in. New products, especially those that address the new consumer reality and... View Details
Keywords: by John Quelch
- November 2023 (Revised April 2024)
- Case
BiomX: Bringing Phage Back to the Stage
By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
Keywords: Working Capital; Financing and Loans; Health Testing and Trials; Product Development; Research and Development; Science-Based Business; Commercialization; Biotechnology Industry; Biotechnology Industry
Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
- November 2007
- Case
Antegren: A Beacon of Hope
By: Joshua D. Margolis, Thomas J. DeLong and Terence Heymann
The CEO of Biogen Idec faces a set of difficult decisions regarding a promising drug for Multiple Sclerosis that is headed for early approval by the FDA. The first in a series focuses on operational decisions triggered by the drive for early approval. Sparks discussion... View Details
Keywords: Demand and Consumers; Leadership; Ethics; Corporate Social Responsibility and Impact; Decision Choices and Conditions; Crisis Management; Health Testing and Trials; Biotechnology Industry; Biotechnology Industry
Margolis, Joshua D., Thomas J. DeLong, and Terence Heymann. "Antegren: A Beacon of Hope." Harvard Business School Case 408-025, November 2007.
- December 2021
- Case
Pairwise
By: José B. Alvarez and Annelena Lobb
Pairwise discusses the strategic approach of a company aiming to “snackify” fruits and vegetables by using CRISPR-Cas9 gene editing to create nutritious, bite-sized foods that could compete with packaged snacks. The company is confronting a number of challenges,... View Details
Keywords: Gene Editing; GMO; Food; Nutrition; Competition; Market Entry and Exit; Public Opinion; Competitive Strategy; Consumer Behavior; Food and Beverage Industry
Alvarez, José B., and Annelena Lobb. "Pairwise." Harvard Business School Case 522-058, December 2021.
- 13 Mar 2014
- Research & Ideas
Can We Get To Where We Need To Go?
those who care about the renewed, continued competitiveness of the United States," he told attendees who gathered recently at the national summit held at HBS, America on the Move: Transportation and Infrastructure for the 21st... View Details
- February 2020
- Teaching Note
Theranos: Who Has Blood on Their Hands? (A) and (B)
By: Nien-he Hsieh and Christina R. Wing
Teaching Note for HBS Nos. 619-039 and 320-091. View Details
- 24 Apr 2018
- First Look
First Look at New Research and Ideas, April 24, 2018
In October 2015, ZappRx founder Zoe Barry is deciding between two business models for her health technology start-up. Her product, a software application that aims to expedite the prescription fulfillment process for patients with rare... View Details
Keywords: Sean Silverthorne
- April 1993 (Revised November 1994)
- Case
Chiron Corp.
Pablo Valenzuela, vice president of R&D at Chiron Corp., faces several choices for how to allocate scarce resources across several promising projects. These choices will determine Chiron's position in several emerging biotechnology and diagnostic markets, including... View Details
Keywords: Health Testing and Trials; Research and Development; Failure; Business Strategy; Joint Ventures; Strategic Planning; Opportunities; Product Development; Biotechnology Industry; California
Wheelwright, Steven C. "Chiron Corp." Harvard Business School Case 693-052, April 1993. (Revised November 1994.)
- March 2023
- Teaching Note
VideaHealth: Building the AI Factory
By: Karim R. Lakhani
Teaching Note for HBS Case No. 621-021. The case “VideaHealth: Building the AI Factory” examines the creation of dental startup VideaHealth (Videa) and the development of its artificial intelligence (AI)-led business strategy through the eyes of founder and CEO Florian... View Details
- October 2014 (Revised July 2016)
- Supplement
Gilead: Hepatitis C Access Strategy (B)
While the "Gilead: Hepatitis-C Access Strategy (A)" case (HBS No. 515-025) poses questions on what the company should do with respect to hard-hit countries like Egypt and India, the (B) case provides the answer. In both cases, the company chose to pursue a proactive... View Details
Rangan, V. Kasturi. "Gilead: Hepatitis C Access Strategy (B)." Harvard Business School Supplement 515-044, October 2014. (Revised July 2016.)
- April 1995 (Revised August 1995)
- Supplement
Empire Blue Cross and Blue Shield (C)
By: Regina E. Herzlinger and Ramona Hilgenkamp
Supplements the (A) case. View Details
Herzlinger, Regina E., and Ramona Hilgenkamp. "Empire Blue Cross and Blue Shield (C)." Harvard Business School Supplement 195-218, April 1995. (Revised August 1995.)
- May 1993
- Case
Alexander Hospital Gift Shoppe
Herzlinger, Regina E. "Alexander Hospital Gift Shoppe." Harvard Business School Case 193-117, May 1993.