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  • All HBS Web  (6,013)
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  • 2023
  • Working Paper

The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’

By: Jacqueline N. Lane
In their Discussion Paper, Franzoni and Stephan (F&S, 2023) discuss the shortcomings of existing peer review models in shaping the funding of risky science. Their discussion offers a conceptual framework for incorporating risk into peer review models of research... View Details
Keywords: Risk and Uncertainty; Research; Resource Allocation; Perception
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Lane, Jacqueline N. "The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’." Harvard Business School Working Paper, No. 23-037, January 2023.
  • June 2025
  • Exercise

Full-Funnel Advertising on TikTok: An Experiment (Solution)

By: Jeremy Yang and Ayelet Israeli
TikTok’s Marketing Science team developed a new type of advertising strategy beyond branding and performance advertising, called full-funnel advertising. Branding ads focused on brand building at the top of the funnel by generating consumer awareness, while performance... View Details
Keywords: Social Media; Advertising; Brands and Branding; Digital Marketing; Marketing Strategy; Measurement and Metrics
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Yang, Jeremy, and Ayelet Israeli. "Full-Funnel Advertising on TikTok: An Experiment (Solution)." Harvard Business School Exercise 525-067, June 2025.
  • June 2025
  • Supplement

Full-Funnel Advertising on TikTok: An Experiment

By: Jeremy Yang and Ayelet Israeli
TikTok’s Marketing Science team developed a new type of advertising strategy beyond branding and performance advertising, called full-funnel advertising. Branding ads focused on brand building at the top of the funnel by generating consumer awareness, while performance... View Details
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Yang, Jeremy, and Ayelet Israeli. "Full-Funnel Advertising on TikTok: An Experiment." Harvard Business School Spreadsheet Supplement 525-721, June 2025.
  • April 2023
  • Article

The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’

By: Jacqueline N. Lane
In their Discussion Paper, Franzoni and Stephan (F&S, 2023) discuss the shortcomings of existing peer review models in shaping the funding of risky science. Their discussion offers a conceptual framework for incorporating risk into peer review models of research... View Details
Keywords: Risk and Uncertainty; Research; Resource Allocation; Perception
Citation
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Lane, Jacqueline N. "The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’." Art. 104707. Research Policy 52, no. 3 (April 2023).
  • 10 May 2016
  • First Look

May 10, 2016

build a literature more effectively than they could with less diverse approaches to gathering data. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=51015 April 29, 2016 Science The Growing Problem of Patent Trolling By:... View Details
Keywords: Carmen Nobel
  • 15 Oct 2013
  • First Look

First Look: October 15

science to consumers. It found it increasingly necessary to direct more of its resources towards marketing, including a major investment in Jennifer Aniston as its celebrity spokesperson. Were they becoming less of a biotech company and... View Details
Keywords: Sean Silverthorne
  • January 2021 (Revised March 2021)
  • Case

THE YES: Reimagining the Future of E-Commerce with Artificial Intelligence (AI)

By: Jill Avery, Ayelet Israeli and Emma von Maur
THE YES, a multi-brand shopping app launched in May 2020 offered a new type of buying experience for women’s fashion, driven by a sophisticated algorithm that used data science and machine learning to create and deliver a personalized store for every shopper, based on... View Details
Keywords: Data; Data Analytics; Artificial Intelligence; AI; AI Algorithms; AI Creativity; Fashion; Retail; Retail Analytics; E-Commerce Strategy; Platform; Platforms; Big Data; Preference Elicitation; Preference Prediction; Predictive Analytics; App Development; "Marketing Analytics"; Advertising; Mobile App; Mobile Marketing; Apparel; Online Advertising; Referral Rewards; Referrals; Female Ceo; Female Entrepreneur; Female Protagonist; Analytics and Data Science; Analysis; Creativity; Marketing Strategy; Brands and Branding; Consumer Behavior; Demand and Consumers; Forecasting and Prediction; Marketing Channels; Digital Marketing; Internet and the Web; Mobile and Wireless Technology; AI and Machine Learning; E-commerce; Digital Platforms; Fashion Industry; Retail Industry; Apparel and Accessories Industry; Consumer Products Industry; United States
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Avery, Jill, Ayelet Israeli, and Emma von Maur. "THE YES: Reimagining the Future of E-Commerce with Artificial Intelligence (AI)." Harvard Business School Case 521-070, January 2021. (Revised March 2021.)
  • December 2007
  • Article

Applying Modern Risk Management to Equity and Credit Analysis

By: Robert C. Merton
Traditional conventions of accounting and actuarial science distort the valuation of capital risk in corporations with pension plans because under these conventions, pension assets and liabilities are not included in balance sheet calculations. The modern risk... View Details
Keywords: Risk Management; Valuation; Financial Reporting; Decision Making; Credit; Financial Statements; Capital; Equity; Compensation and Benefits
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Merton, Robert C. "Applying Modern Risk Management to Equity and Credit Analysis." CFA Institute Conference Proceedings Quarterly 24 (December 2007): 14–22.
  • 04 Oct 2019
  • Working Paper Summaries

Soul and Machine (Learning)

Keywords: by Davide Proserpio, John R. Hauser, Xiao Liu, Tomomichi Amano et al.
  • Editorial

Zeroing Out on zero-COVID

By: William C. Kirby
China’s culture reveres science, yet operates under a government that often defines what “science” is and is not. China’s “zero-COVID” policy has created a bifurcated scientific community that threatens international collaboration in science and technology. A... View Details
Keywords: COVID; Scientific Community; World Health Organization; Pseudoscience; Governance; Government and Politics; Health; Research and Development; Social Media; China
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Kirby, William C. "Zeroing Out on zero-COVID." Science 376, no. 6597 (June 2, 2022): 1026.
  • June 2009 (Revised April 2011)
  • Case

Cincinnati Children's Hospital Medical Center

By: Anita L. Tucker and Amy C. Edmondson
The case describes an organization's use of the science of improvement to transform their process quality from below average to the top 10% in their industry. The case outlines the protagonist's strategy of developing internal experts who are trained in a common... View Details
Keywords: Change Management; Experience and Expertise; Leading Change; Measurement and Metrics; Service Delivery; Performance Improvement; Health Industry; Ohio
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Tucker, Anita L., and Amy C. Edmondson. "Cincinnati Children's Hospital Medical Center." Harvard Business School Case 609-109, June 2009. (Revised April 2011.)
  • November 2006 (Revised March 2008)
  • Case

The Harvard Stem Cell Institute

By: William A. Sahlman
Describes a set of issues confronting the leaders of the Harvard Stem Cell Institute, an innovative cross-university effort to accelerate scientific discovery and translation in the domain of stem cells. Covers a wide range of topics, including understanding how... View Details
Keywords: Talent and Talent Management; Higher Education; Entrepreneurship; Collaborative Innovation and Invention; Intellectual Property; Research and Development; Genetics; Biotechnology Industry; Health Industry; Massachusetts
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Sahlman, William A. "The Harvard Stem Cell Institute." Harvard Business School Case 807-096, November 2006. (Revised March 2008.)
  • June 2025
  • Exercise

Full-Funnel Advertising on TikTok: An Experiment

By: Jeremy Yang and Ayelet Israeli
TikTok’s Marketing Science team developed a new type of advertising strategy beyond branding and performance advertising, called full-funnel advertising. Branding ads focused on brand building at the top of the funnel by generating consumer awareness, while performance... View Details
Keywords: Social Media; Advertising; Brands and Branding; Digital Marketing; Marketing Strategy; Measurement and Metrics
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Yang, Jeremy, and Ayelet Israeli. "Full-Funnel Advertising on TikTok: An Experiment." Harvard Business School Exercise 525-066, June 2025.
  • 27 Aug 2008
  • Research & Ideas

Creating Leaders for Science-Based Businesses

It's been said that in this century, carbohydrates will replace hydrocarbons, and biology will supplant physics as the innovation-producing science. As science fiction becomes science fact, and with... View Details
Keywords: by Garry Emmons; Biotechnology; Health
  • October 2023 (Revised June 2024)
  • Case

Revvity: A Symbol of Change

By: Satish Tadikonda and William Marks
After selling the PerkinElmer name and several ancillary business units, Prahlad Singh (CEO) and his team at the newly christened Revvity faced a challenge on how best to capitalize on the opportunities ahead for the business and emerge as winners within the Life... View Details
Keywords: Business Model; Organizational Change and Adaptation; Corporate Strategy
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Tadikonda, Satish, and William Marks. "Revvity: A Symbol of Change." Harvard Business School Case 824-071, October 2023. (Revised June 2024.)
  • November 2007 (Revised March 2009)
  • Case

Allston: Brand vs. Architecture

By: Andre F. Perold, Arthur I Segel and Christopher M. Gordon
Harvard President Lawrence Summers had presided over the final interviews of world-renowned architects being considered for the science complex planned for Harvard's expanded campus in Allston. The selection process had absorbed nine months in 2005 and amplified the... View Details
Keywords: Decision Choices and Conditions; Brands and Branding; Design; Urban Development; Selection and Staffing; Construction Industry; Boston
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Perold, Andre F., Arthur I Segel, and Christopher M. Gordon. "Allston: Brand vs. Architecture." Harvard Business School Case 208-079, November 2007. (Revised March 2009.)
  • June 2004 (Revised November 2004)
  • Case

Acorda Therapeutics: Rebuilding the Spinal Cord

Acorda is an early-stage life science start-up with a promising product that is close to reaching the market (Phase III clinical trials). The company is grappling with how to expand its portfolio of molecules to make the business more sustainable. It faces classic... View Details
Keywords: Decision Making; Science-Based Business; Health Testing and Trials; Business Startups; Product Development; Biotechnology Industry
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Enriquez-Cabot, Juan, Jonathan West, Marina Kolesnik, and Fiona Murray. "Acorda Therapeutics: Rebuilding the Spinal Cord." Harvard Business School Case 604-014, June 2004. (Revised November 2004.)
  • December 2016
  • Case

SEAS in 2016

By: Thomas R. Eisenmann and Kerry Herman
The case explores opportunities and challenges facing the Harvard School of Engineering and Applied Sciences as it 1) grapples with rapid undergraduate enrollment growth and its smaller scale relative to other top engineering schools and 2) prepares to move two-thirds... View Details
Keywords: Business Education; Engineering; Strategy; Partners and Partnerships; Change Management; Education Industry; United States
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Eisenmann, Thomas R., and Kerry Herman. "SEAS in 2016." Harvard Business School Case 817-063, December 2016.
  • November 2023 (Revised April 2024)
  • Case

Khanmigo: Revolutionizing Learning with GenAI

By: William A. Sahlman, Allison M. Ciechanover and Emily Grandjean
Already a leader in the edtech space since its 2008 launch, Khan Academy was now one of the first edtech organizations to embrace generative artificial intelligence ("genAI"). In March 2023, Khan Academy began beta testing Khanmigo, a genAI “guide” and tutor built with... View Details
Keywords: Technology Adoption; Leading Change; Entrepreneurship; Risk and Uncertainty; Education; AI and Machine Learning; Corporate Social Responsibility and Impact; Education Industry; Technology Industry; United States; San Francisco
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Sahlman, William A., Allison M. Ciechanover, and Emily Grandjean. "Khanmigo: Revolutionizing Learning with GenAI." Harvard Business School Case 824-059, November 2023. (Revised April 2024.)
  • 06 Sep 2006
  • Lessons from the Classroom

Mixing Students and Scientists in the Classroom

integrated-circuit testing, admits it was anything but inevitable that he would end up at HBS. "I was interested in science and technology policy at the Kennedy School, and I also thought about law school," notes Fleming, who... View Details
Keywords: by Deborah Blagg; Education
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