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  • All HBS Web  (1,022)
    • News  (154)
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  • Faculty Publications  (441)
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  • June 2016
  • Teaching Note

N12 Technologies: Building an Organization and Building a Business

By: David A. Garvin
N12 Technologies was a startup founded in 2010 that employed nanotechnology to manufacture a patented material to improve the performance of carbon fiber composites, which were used in a wide variety of products, ranging from bicycles to automobiles to aircraft parts.... View Details
Keywords: Startup; Organizational Structure; Nanotechnology; Business Processes; Organizational Change and Adaptation; Organizational Design; Management Systems; Commercialization; Industrial Products Industry; Manufacturing Industry; Auto Industry; Bicycle Industry; Transportation Industry; United States
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Garvin, David A. "N12 Technologies: Building an Organization and Building a Business." Harvard Business School Teaching Note 316-187, June 2016.
  • May 2014 (Revised January 2015)
  • Case

Vaxess Technologies, Inc.

By: John A. Quelch and Margaret L. Rodriguez
In February 2014, Michael Schrader, chief executive of Vaxess Technologies, Inc., was assessing the startup health care company's 2014 marketing plan. On December 31st, 2013, Vaxess had obtained an exclusive license to a series of patents for a silk protein technology... View Details
Keywords: Vaccine; Cold Chain; Antigen; Temperature Controlled; Developing Markets; Immunization; Health Care and Treatment; Health Pandemics; Global Strategy; Supply Chain; Health; Health Industry; Medical Devices and Supplies Industry
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Quelch, John A., and Margaret L. Rodriguez. "Vaxess Technologies, Inc." Harvard Business School Case 514-107, May 2014. (Revised January 2015.)
  • March 1992 (Revised June 1995)
  • Case

Introduction of FM Radio (A): Finally, A ""Staticless"" Radio

Describes the evolution of radio technology and business from the initial days of wireless telegraphy to the advent, growth, and establishment of amplitude-modulated (AM) radio manufacturing and broadcasting. Begins and ends with a description of a decision the Radio... View Details
Keywords: Technological Innovation; Leading Change; Product Design; Product Development; Media and Broadcasting Industry; United States
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Dhebar, Anirudh S. Introduction of FM Radio (A): Finally, A ""Staticless"" Radio. Harvard Business School Case 592-092, March 1992. (Revised June 1995.)
  • 2009
  • Working Paper

Breakthrough Inventions and Migrating Clusters of Innovation

By: William R. Kerr
We investigate the speed at which clusters of invention for a technology migrate spatially following breakthrough inventions. We identify breakthrough inventions as the top one percent of US inventions for a technology during 1975-1984 in terms of subsequent citations.... View Details
Keywords: Geographic Location; Immigration; Disruptive Innovation; Technological Innovation; Patents; Industry Clusters; United States
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Kerr, William R. "Breakthrough Inventions and Migrating Clusters of Innovation." Harvard Business School Working Paper, No. 10-020, September 2009.
  • Winter 2021
  • Article

Can Staggered Boards Improve Value? Causal Evidence from Massachusetts

By: Robert Daines, Shelley Xin Li and Charles C.Y. Wang
We study the effect of staggered boards (SBs) using a quasi-experiment: a 1990 law that imposed an SB on all Massachusetts-incorporated firms. The law led to an increase in Tobin's Q, investment in CAPEX and R&D, patents, higher-quality patented innovations, and... View Details
Keywords: Staggered Board; Entrenchment; Life-cycle; Tobin's Q; Innovation; Profitability; Investor Composition; Governing and Advisory Boards; Investment; Innovation and Invention; Institutional Investing; Value
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Daines, Robert, Shelley Xin Li, and Charles C.Y. Wang. "Can Staggered Boards Improve Value? Causal Evidence from Massachusetts." Contemporary Accounting Research 38, no. 4 (Winter 2021): 3053–3084.
  • April 2023
  • Case

Elliott Management: Capital Allocation in Biopharma

By: Amitabh Chandra, Paul Clancy and Lauren Gunasti
The case explores the intersection of capital allocation and shareholder activism in the biopharmaceutical industry. As many biopharma companies face looming patent expirations for key medicines, the case asks the question of whether investing in R&D and M&A is an... View Details
Keywords: Finance; Strategy; Capital Allocation; Biopharmaceutical Industry; Shareholder Activism; Investment Activism; Resource Allocation; Research and Development; Business and Shareholder Relations; Corporate Strategy; Pharmaceutical Industry
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Chandra, Amitabh, Paul Clancy, and Lauren Gunasti. "Elliott Management: Capital Allocation in Biopharma." Harvard Business School Case 623-045, April 2023.
  • March 2020
  • Article

Do Managers Matter? A Natural Experiment from 42 R&D Labs in India

By: Prithwiraj Choudhury, Tarun Khanna and Christos A. Makridis
We exploit plausibly exogenous variation in the staggered entry of new managers into India’s 42 public R&D labs between 1994 and 2006 to study how alignment between the CEO and middle-level managers affect research productivity. We show that the introduction of new lab... View Details
Keywords: Incentives; Innovation; Productivity; Management; Alignment; Research and Development; Innovation and Invention; Performance Productivity; India
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Choudhury, Prithwiraj, Tarun Khanna, and Christos A. Makridis. "Do Managers Matter? A Natural Experiment from 42 R&D Labs in India." Journal of Law, Economics & Organization 36, no. 1 (March 2020): 47–83.
  • 2018
  • Working Paper

Taxation and Innovation in the 20th Century

By: Ufuk Akcigit, John Grigsby, Tom Nicholas and Stefanie Stantcheva
This paper studies the effect of corporate and personal taxes on innovation in the United States over the 20th century. We use three new datasets: a panel of the universe of inventors who patent since 1920; a dataset of the employment, location, and patents of firms... View Details
Keywords: Taxation; Innovation and Invention; History; United States
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Akcigit, Ufuk, John Grigsby, Tom Nicholas, and Stefanie Stantcheva. "Taxation and Innovation in the 20th Century." NBER Working Paper Series, No. 24982, September 2018. (Forthcoming in Quarterly Journal of Economics.)
  • May 2016
  • Article

Return Migration and Geography of Innovation in MNEs: A Natural Experiment of Knowledge Production by Local Workers Reporting to Return Migrants

By: Prithwiraj Choudhury
I study whether return migrants facilitate knowledge production by local employees working for them at geographically distant R&D locations. Using unique personnel and patenting data for 1,315 employees at the Indian R&D center of a Fortune 500 technology firm, I... View Details
Keywords: Innovation; Innovation and Invention
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Choudhury, Prithwiraj. "Return Migration and Geography of Innovation in MNEs: A Natural Experiment of Knowledge Production by Local Workers Reporting to Return Migrants." Journal of Economic Geography 16, no. 3 (May 2016): 585–610.
  • December 2006 (Revised October 2007)
  • Case

Monsanto: Realizing Biotech Value in Brazil

By: David E. Bell and Mary L. Shelman
In 2003, Monsanto's patented "Roundup Ready" technology was used illegally on 70-80% of the soybean area in southern Brazil. Under pressure from U.S. soybean growers, who were paying to license the technology, the firm implemented an innovative delivery-based... View Details
Keywords: Plant-Based Agribusiness; Patents; Lawfulness; Emerging Markets; Product Development; Agriculture and Agribusiness Industry; Biotechnology Industry; Brazil
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Bell, David E., and Mary L. Shelman. "Monsanto: Realizing Biotech Value in Brazil." Harvard Business School Case 507-018, December 2006. (Revised October 2007.)
  • August 2020
  • Article

Machine Learning and Human Capital Complementarities: Experimental Evidence on Bias Mitigation

By: Prithwiraj Choudhury, Evan Starr and Rajshree Agarwal
The use of machine learning (ML) for productivity in the knowledge economy requires considerations of important biases that may arise from ML predictions. We define a new source of bias related to incompleteness in real time inputs, which may result from strategic... View Details
Keywords: Machine Learning; Bias; Human Capital; Management; Strategy
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Choudhury, Prithwiraj, Evan Starr, and Rajshree Agarwal. "Machine Learning and Human Capital Complementarities: Experimental Evidence on Bias Mitigation." Strategic Management Journal 41, no. 8 (August 2020): 1381–1411.
  • 2014
  • Chapter

Technology, Innovation and Economic Growth in Britain Since 1870

By: Tom Nicholas
This chapter examines technological change in Britain over the last 140 years. It analyzes the effects of patent laws and innovation prizes that were designed to promote technical progress. It explores the challenge associated with the changing organizational structure... View Details
Keywords: Information Technology; Organizational Change and Adaptation; History; Economic Growth; Change; Innovation and Invention; Great Britain
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Nicholas, Tom. "Technology, Innovation and Economic Growth in Britain Since 1870." Chap. 7, Vol. 2 of The Cambridge Economic History of Modern Britain. New ed. Edited by Roderick Floud, Jane Humphries, and Paul Johnson, 181–204. Cambridge University Press, 2014.
  • February 2015
  • Article

'Open' Disclosure of Innovations, Incentives and Follow-on Reuse: Theory on Processes of Cumulative Innovation and a Field Experiment in Computational Biology

By: Kevin J. Boudreau and Karim R. Lakhani
Most of society's innovation systems―academic science, the patent system, open source, etc.―are "open" in the sense that they are designed to facilitate knowledge disclosure among innovators. An essential difference across innovation systems is whether disclosure is of... View Details
Keywords: Open Innovation; Cumulative Innovation; Incentives; Search; Disclosure And Access; Knowledge Sharing; Motivation and Incentives; Collaborative Innovation and Invention
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Boudreau, Kevin J., and Karim R. Lakhani. "'Open' Disclosure of Innovations, Incentives and Follow-on Reuse: Theory on Processes of Cumulative Innovation and a Field Experiment in Computational Biology." Research Policy 44, no. 1 (February 2015): 4–19.
  • September 1993
  • Case

Manufacturing at ALZA: The Right Prescription? (A)

By: Dorothy A. Leonard
ALZA, a company specializing in drug delivery systems such as transdermal patches, considers manufacturing its own products. Until now, the company has conducted research and development on its patented system but has then licensed the technology to client-partner... View Details
Keywords: Business or Company Management; Technological Innovation; Innovation and Management; Growth and Development Strategy; Problems and Challenges; Production; Research and Development; Organizational Change and Adaptation; Pharmaceutical Industry; Medical Devices and Supplies Industry
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Leonard, Dorothy A. "Manufacturing at ALZA: The Right Prescription? (A)." Harvard Business School Case 694-019, September 1993.
  • 26 Jul 2016
  • Working Paper Summaries

The Impact of the Entry of Biosimilars: Evidence from Europe

Keywords: by Fiona Scott Morton, Ariel Dora Stern, and Scott Stern; Health; Biotechnology; Pharmaceutical
  • Research Summary

Overview

The research activity of Stefano Denicolai regards the management of innovation and technology. His recent works investigate if and how the investment in intangible assets (IA) - especially knowledge assets, such as patents or copyright - impacts on the firm... View Details
Keywords: Innovation Management; International Entrepreneurship; Intangible Assets; Open Innovation; Innovation and Management; Entrepreneurship; Competitive Strategy; Technology Industry; Biotechnology Industry; Web Services Industry; Tourism Industry
  • May 2004
  • Background Note

56K Modem Battle

By: David B. Yoffie and Deborah Freier
Examines the battle to set the standard for the 56K modem. Set in 1996, this case looks at how computers accessed the Internet via a telephone line, or dial-up connection, and a hardware modem. In 1995, there were 18.6 million total modem unit shipments, with market... View Details
Keywords: Announcements; Revenue; Patents; Product Launch; Network Effects; Standards; Competition; Information Infrastructure; Internet and the Web; Technology Industry; Illinois
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Yoffie, David B., and Deborah Freier. "56K Modem Battle." Harvard Business School Background Note 704-501, May 2004.
  • February 2001 (Revised February 2002)
  • Background Note

Leader's (Dis)Advantage, The

Provides a rigorous description of the economic dynamics that may produce inherent advantages for large and/or first-mover firms within an industry, as well as those factors that may result in disadvantages for such leading firms. The leader advantages discussed... View Details
Keywords: Competitive Advantage; Semiconductor Industry
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Coughlan, Peter J. "Leader's (Dis)Advantage, The." Harvard Business School Background Note 701-084, February 2001. (Revised February 2002.)
  • 2018
  • Working Paper

Intellectual Baggage of Ethnic Migrant Inventors: Transfer and Recombination of Knowledge Across Borders

By: Prithwiraj Choudhury
Ethnic migrant inventors might differ from locals in terms of knowledge they bring to host firms. We study the role of first-generation ethnic migrant inventors in cross-border transfer of knowledge previously locked within the cultural context of their home regions.... View Details
Keywords: Skilled Migration; Ethnic Migration; First-generation Migrant; Cultural Context; Knowledge Flows; Knowledge Reuse; Knowledge Recombination; Recombinant Creation; H1B Visas; Knowledge Sharing; Knowledge Use and Leverage; Knowledge Dissemination; Immigration; Ethnicity
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Choudhury, Prithwiraj. "Intellectual Baggage of Ethnic Migrant Inventors: Transfer and Recombination of Knowledge Across Borders." Harvard Business School Working Paper, No. 17-069, January 2017. (Revised January 2018.)
  • 2007
  • Working Paper

Noncompetes and Inventor Mobility: Specialists, Stars, and the Michigan Experiment

Several scholars have documented the positive consequences of job-hopping by inventors, including knowledge spillovers and agglomeration and the concentration of spinoffs. This work investigates a possible antecedent of inventor mobility: regional variation in the... View Details
Keywords: Contracts; Laws and Statutes; Intellectual Property; Innovation and Invention; Michigan
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Marx, Matt, Deborah Strumsky, and Lee Fleming. "Noncompetes and Inventor Mobility: Specialists, Stars, and the Michigan Experiment." Harvard Business School Working Paper, No. 07-042, January 2007.
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