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  • 01 Aug 2017
  • First Look

First Look at New Research and Ideas, August 1

Abstract—Objective: Assess whether a commitment contract informed by behavioral economics leads to persistent virologic suppression among HIV-positive patients with poor antiretroviral therapy (ART) adherence. Design: Single-center pilot randomized clinical View Details
Keywords: Sean Silverthorne
  • 24 Apr 2014
  • News

Giving hope and inspiration to cancer patients around the globe

data and share it globally. The organization also spearheads a clinical network of 16 research centers to conduct early-phase clinical trials faster and more efficiently. By... View Details
  • 12 Aug 2019
  • Working Paper Summaries

Case Histories of Significant Medical Advances

Keywords: by Amar Bhidé, Srikant M. Datar, and Katherine Stebbins

    Who Benefits Most in Disease Management Programs?

    Disease management programs aim to reduce cost by improving the quality of care for chronic diseases. Evidence of their effectiveness is mixed. Reducing health care spending sufficiently to cover program costs has proved particularly challenging. This study uses a... View Details
    • 16 May 2017
    • First Look

    First Look at New Ideas and Research, May 16

    health of the enterprise rather than near-term returns to its shareholders. Their model would refocus companies’ attention to innovation, strategic renewal, and investment in the future. Publisher's link:... View Details
    Keywords: Re: Multiple Faculty
    • 2008
    • Article

    Entrepreneurial Ventures and Whole-body Donations: A Regional Perspective from the United States

    By: Michel Anteby and Mikell Hyman

    Human cadavers are crucial to medical science. While the debate on how to secure sufficient cadavers has focused primarily on donors' behaviors, procuring organizations' roles in increasing donations remain less explored. The United States offers a unique setting in... View Details

    Keywords: Entrepreneurship; Behavior; Programs; Nonprofit Organizations; Business Ventures; Health Testing and Trials; Demand and Consumers; Supply Chain; For-Profit Firms; Organizations; Training; United States
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    • April 2014 (Revised July 2015)
    • Case

    Sanofi Pasteur: The Dengue Vaccine Dilemma

    By: V. Kasturi Rangan, David E. Bloom, Vincent Dessain and Emilie Billaud
    In 2012, Sanofi Pasteur was racing to develop a vaccine against dengue, a mosquito-borne disease, and was evaluating this product in a Phase IIb trial conducted with school children in Thailand. But while the candidate vaccine met the high safety expectations and a... View Details
    Keywords: Health Testing and Trials; Product Launch; Market Entry and Exit; Emerging Markets; Pharmaceutical Industry; France
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    • 06 Feb 2018
    • First Look

    First Look at New Research and Ideas: February 6, 2018

    communities) and the moderating effects of team leader experience. We test our moderated mediation model in a sample of 121 teams that filed patents in a Fortune 50 company’s India R&D center between... View Details
    • 2006
    • Chapter

    BioRisk: interleukin-2 from laboratory to market in the United States and Germany

    By: Arthur A. Daemmrich
    Keywords: Product Development; Risk and Uncertainty; Health Testing and Trials; Pharmaceutical Industry; Biotechnology Industry; United States; Germany
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    • 26 Sep 2017
    • First Look

    First Look at New Research and Ideas, September 26, 2017

    article proposes that the review process initially be adopted on a pilot basis. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=53264 September 2017 Health Affairs Narrow Networks on the View Details
    Keywords: Sean Silverthorne
    • 16 Oct 2013
    • Op-Ed

    Response to Readers: Combating Climate Change with Nuclear Power and Fracking

    deaths due to severe smog (estimated between 3,000 to more recently 10,000 in London between December 1952 and March 1953) now officially acknowledged and seemingly routine in China today as well as coal... View Details
    Keywords: by Joe Lassiter; Energy; Utilities
    • 29 Jun 2020
    • News

    After saving his own life with a repurposed drug, a professor reviews every drug being tried against Covid-19. Here's what he's found

    • 24 Apr 2014
    • News

    Transforming the way the social sector innovates, learns, and improves

    In Zambia and Uganda, it partnered with the Clinton Health Access Initiative and the Ministries of Health to test... View Details
    • March 2015 (Revised February 2022)
    • Supplement

    CV Ingenuity (B): Epilogue

    By: Regina E. Herzlinger and Andrew Otazo
    Duke Rohlen used a lea-nfunding, iconoclastic strategy for his start up for a drug eluding balloon for peripheral artery disease. His giant competitors were first movers. Did Duke obtain the funding he sought? How did his DEB fare versus that of his competitors? The... View Details
    Keywords: CV Ingenuity; CVI; Drug Eluting Balloon; DEB; Drug Eluting Stent; Angioplasty Balloon; FoxHollow; Medical Device; Medical Device Startup; Premarket Approval; PMA; Lutonix; Stellarex; LEVANT; ILLUMENATE; Clinical Trials; Peripheral Arterial Disease; PAD; Healthcare Startups; Covidien; Health Care and Treatment; Health Testing and Trials; Business Startups; Commercialization; Strategy; Health Industry; Health Industry; United States; Europe
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    • 28 May 2019
    • Research & Ideas

    Investor Lawsuits Against Auditors Are Falling, and That's Bad News for Capital Markets

    mistake made. Our tests show that previously when there have been serious restatements of financials, those mistakes would lead to a certain number of lawsuits being filed and a certain settlement amount... View Details
    Keywords: by Martha Lagace; Financial Services; Accounting
    • 23 May 2017
    • First Look

    First Look at New Ideas and Research: May 23, 2017

    about the causes of regional variations in health care expenditures. We use vignettes from patient and physician surveys linked to fee-for-service Medicare expenditures to test... View Details
    Keywords: Carmen Nobel
    • 24 Apr 2018
    • First Look

    First Look at New Research and Ideas, April 24, 2018

    and financial outcomes. The study complements financial education with (1) financial incentives on a financial literacy test to affect participant motivation, (2) financial goal setting to provide a... View Details
    Keywords: Sean Silverthorne
    • 17 Oct 2017
    • First Look

    First Look at New Research and Ideas, October 17, 2017

    patient satisfaction, and problems with patient safety. Nearly all U.S. health care organizations have used similar evidence to justify their investments in safety and quality.... View Details
    Keywords: Sean Silverthorne
    • November 2009 (Revised March 2010)
    • Case

    Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

    By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
    In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details
    Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States
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    • February 2009
    • Case

    Avid Radiopharmaceuticals: The Venture Debt Question

    By: Matthew Rhodes-Kropf and Ann Leamon
    The CEO of a promising biotech company must decide how to respond to the macro-economic slump of late 2008. He had planned to pursue an aggressive schedule, moving the firm's Alzheimer's and Parkinson's disease imaging compounds through clinical trials and into the... View Details
    Keywords: Financial Crisis; Entrepreneurship; Borrowing and Debt; Venture Capital; Financial Management; Investment; Health Testing and Trials; Expansion; Biotechnology Industry; Pharmaceutical Industry
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