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July 2006 (Revised July 2007)
Case

C.K. Coolidge, Inc. (Abridged)

Coolidge (CKC), a chemical manufacturer, is being sued for patent infringement. The plaintiffs are the patent holder and its sole licensee, who is also a CKC competitor. An analyst at CKC has done a breakeven decision analysis from CKC's perspective, balancing going to... View Details

Keywords: Negotiation Preparation; Courts and Trials; Patents; Analysis; Decision Choices and Conditions; Lawsuits and Litigation; Chemical Industry

April 2014 (Revised July 2015)
Case

Sanofi Pasteur: The Dengue Vaccine Dilemma

By: V. Kasturi Rangan, David E. Bloom, Vincent Dessain and Emilie Billaud

In 2012, Sanofi Pasteur was racing to develop a vaccine against dengue, a mosquito-borne disease, and was evaluating this product in a Phase IIb trial conducted with school children in Thailand. But while the candidate vaccine met the high safety expectations and a... View Details

Keywords: Health Testing and Trials; Product Launch; Market Entry and Exit; Emerging Markets; Pharmaceutical Industry; France

February 2009
Case

Avid Radiopharmaceuticals: The Venture Debt Question

By: Matthew Rhodes-Kropf and Ann Leamon

The CEO of a promising biotech company must decide how to respond to the macro-economic slump of late 2008. He had planned to pursue an aggressive schedule, moving the firm's Alzheimer's and Parkinson's disease imaging compounds through clinical trials and into the... View Details

Keywords: Financial Crisis; Entrepreneurship; Borrowing and Debt; Venture Capital; Financial Management; Investment; Health Testing and Trials; Expansion; Biotechnology Industry; Pharmaceutical Industry

March 2015 (Revised February 2022)
Supplement

CV Ingenuity (B): Epilogue

By: Regina E. Herzlinger and Andrew Otazo

Duke Rohlen used a lea-nfunding, iconoclastic strategy for his start up for a drug eluding balloon for peripheral artery disease. His giant competitors were first movers. Did Duke obtain the funding he sought? How did his DEB fare versus that of his competitors? The... View Details

12 Aug 2019
Working Paper Summaries

Case Histories of Significant Medical Advances

Keywords: by Amar Bhidé, Srikant M. Datar, and Katherine Stebbins

Web

New Levels of Capitalism: Finance - Railroads and the Transformation of Capitalism | Harvard Business School

were coproductions. . . . Congress and the courts created ways in which corporations could fail repeatedly and arise again.” 23 US Railroads Management Site Credits Petition to... View Details

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Health; Biotechnology; Pharmaceutical; Medical Devices & Supplies

Article

The Impact of Intangibles on Firm Growth

By: Stefano Denicolai, E. Cotta Ramusino and F. Sotti

Persuading users to try new technologies continues to be a problem confronting organisations and technology vendors alike. To better understand the process of new technology trial and adoption, several theoretical models have been proposed, of which the Technology... View Details

Keywords: Motivation and Incentives; Technology Adoption

Find at Harvard

November 2009 (Revised August 2010)
Case

NovoCure Ltd.

By: William A. Sahlman and Sarah Flaherty

Venture capitalist William Doyle must raise $35 million for a portfolio company with a promising, novel cancer therapy, just as global capital markets are imploding in the fall of 2008. NovoCure, Ltd., has developed an electrical-field-based therapy, called Tumor... View Details

Keywords: Financial Crisis; Entrepreneurship; Venture Capital; Investment; Health Care and Treatment; Health Testing and Trials; Technological Innovation; Financial Services Industry

01 Mar 2015
News

Debt-Saddled Municipal Budgets Get a Lifeline

19 May 2016
Research Event

Crowdsourcing, Patent Trolls, and Other Research Insights Highlighted at Harvard Business School Symposium

dispute to court can be an expensive proposition. Cohen shared an example: Lumen View Technology, which had initiated patent lawsuits in the past against numerous companies, sued FindTheBest and several... View Details

Keywords: by Dina Gerdeman & Carmen Nobel

Fall 2020
Article

Sizing Up Corporate Restructuring in the COVID Crisis

By: Robin Greenwood, Benjamin Iverson and David Thesmar

In the wake of the COVID-19 pandemic, the financial and legal system will need to deal with a surge of financial distress in the business sector. Some firms will be able to survive, while others will face bankruptcy and thus need to be liquidated or reorganized. Many... View Details

Keywords: COVID-19; Health Pandemics; Economy; System Shocks; Financial Crisis; Restructuring

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28 Oct 2024
Op-Ed

Latino Voters Have Grown More Politically Divided. That’s Not Surprising.

vehicles—political parties fight for votes where they can get them. If a group of voters starts to grow, then both parties will court that group with campaign effort, messaging, and policy change. And, in... View Details

Keywords: by Richard Calvo, Vincent Pons, and Jesse M. Shapiro

15 Dec 2010
News

Should sensitive events be used in ads?

November 2020
Teaching Note

DayTwo: Going to Market with Gut Microbiome

By: Ayelet Israeli

Teaching Note for HBS Case No. 519-010. DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals.... View Details