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  • 09 Apr 2013
  • First Look

First Look: April 9

offered by Blue Cross Blue Shield of Massachusetts, providers received a fixed-dollar budget to cover all care provided to a specific patient population, as well as incentive payments for quality. The AQC... View Details
Keywords: Sean Silverthorne
  • 27 Aug 2013
  • First Look

First Look: August 27

Factory Models for Cancer Care This case compares and contrasts four different models for delivering cancer care View Details
Keywords: Sean Silverthorne
  • 26 Nov 2013
  • First Look

First Look: November 26

that increased the number of doctors and nurses serving patients, expanded existing staff roles and developed new ones, redistributed health care work, and invested in... View Details
Keywords: Sean Silverthorne
  • September 2018 (Revised December 2019)
  • Case

Zebra Medical Vision

By: Shane Greenstein and Sarah Gulick
An Israeli startup founded in 2014, Zebra Medical Vision developed algorithms that produced diagnoses from X-rays, mammograms, and CT-scans. The algorithms used deep learning and digitized radiology scans to create software that could assist doctors in making... View Details
Keywords: Radiology; Machine Learning; X-ray; CT Scan; Medical Technology; Probability; FDA 510(k); Diagnosis; Business Startups; Health Care and Treatment; Information Technology; Applications and Software; Competitive Strategy; Product Development; Commercialization; Decision Choices and Conditions; Health Industry; Medical Devices and Supplies Industry; Technology Industry; Israel
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  • 21 Nov 2017
  • First Look

First Look at New Research and Ideas, November 21, 2017

in Medicare managed care (i.e., Medicare Advantage) plans. CareMore's President, Sachin Jain, and his colleagues believed their model achieved the elusive goal of improving... View Details
Keywords: Sean Silverthorne
  • 19 Oct 2010
  • First Look

First Look: October 19, 2010

Raffaella Sadun, and John Van Reenen Publication:American Economic Review (forthcoming) Abstract The U.S. has experienced a sustained increase in productivity growth since... View Details
Keywords: Sean Silverthorne
  • 25 Jul 2017
  • First Look

First Look at New Research and Ideas: July 25, 2017

experience physical improvements? In this paper, we introduce a computer vision method to measure changes in the physical appearances of neighborhoods from time-series... View Details
Keywords: Carmen Nobel
  • September 2021 (Revised October 2022)
  • Supplement

Hester Pharmaceuticals (B): Securing Supply

By: Dante Roscini and John Masko
Supplements the (A) case. In late 2020, demand for Hester Pharmaceutical’s (Hester’s) breakthrough oncology drug Akrozumab was outstripping the company’s most optimistic projections. In order to increase manufacturing capacity and meet the demand, Hester was... View Details
Keywords: COVID-19 Pandemic; Cost vs Benefits; Trade; Supply Chain; Global Strategy; Buildings and Facilities; Operations; Health Care and Treatment; Demand and Consumers; Global Range; Globalized Markets and Industries; Pharmaceutical Industry; Italy; China; United States; Germany
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  • August 2023
  • Case

Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company

By: Satish Tadikonda and Brad Prosek
Constellation Pharmaceuticals was a company focused on epigenetic therapies for cancer patients. Despite a promising start and an early deal with a leading biopharma company, the company weathered twin setbacks in the end of a major research collaboration and the... View Details
Keywords: Mergers and Acquisitions; Health Care and Treatment; Organizational Change and Adaptation; Research and Development; Business Strategy; Partners and Partnerships; Goals and Objectives; Pharmaceutical Industry; United States
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  • Article

Cybersecurity Features of Digital Medical Devices: An Analysis of FDA Product Summaries

By: Ariel Dora Stern, William J. Gordon, Adam B. Landman and Daniel B. Kramer
Objectives:
To more clearly define the landscape of digital medical devices subject to U.S. Food and Drug Administration (FDA) oversight, this analysis leverages publicly available regulatory documents to characterise the prevalence and trends of software and... View Details
Keywords: Digital; Medicine; FDA; Health Care and Treatment; Applications and Software; Safety; Cybersecurity; Medical Devices and Supplies Industry
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  • October 2009 (Revised July 2013)
  • Case

Gilead Sciences, Inc.: Access Program

By: V. Kasturi Rangan and Katharine Lee
Gilead Sciences, the U.S. leader in HIV/AIDS medicines, with global sales of $5.4 billion in 2009, had undertaken several innovative actions to make its anti-viral products available to over 100 low- and middle-income countries. Having reached nearly 680,000 patients... View Details
Keywords: Health Care and Treatment; Emerging Markets; Product; Sales; Competitive Strategy; Biotechnology Industry; Pharmaceutical Industry
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  • 2022
  • Article

Improving Efficiency and Reducing Costs of MRI-Guided Prostate Brachytherapy Using Time-Driven Activity-Based Costing

By: Nikhil G. Thaker, Rajat J. Kudchadker, James R. Incalcaterra, Tharakeswara K. Bathala, Robert S. Kaplan, Ankit Agarwal, Deborah A. Kuban, Benjamin D. Frank, Prajnan Das, Thomas W. Feeley and Steven J. Frank
Integrated quality improvement (QI) and cost reduction strategies can help increase value in cancer care. We applied standard QI and TDABC methods to improve workflow efficiency and reduce costs for MRI-guided prostate brachytherapy. We constructed process maps,... View Details
Keywords: Brachytherapy; Quality Improvement; Prostate; Time-Driven Activity-Based Costing; Cost Accounting; Health Care and Treatment; Performance Efficiency; Health Industry
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  • 2024
  • Working Paper

Fecal Microbiota Transplants —Too Simple to be Safe? Case Histories of Transformational Advances

By: Amar Bhide and Srikant M. Datar
By 2013, after many decades of very slow development and adoption, Fecal Microbiota Transplantation procedures were attracting widespread attention. This case history chronicles the: 1) pioneering fecal transplants performed in the 20th century; 2) development of the... View Details
Keywords: Health Care and Treatment; Innovation and Invention; Governing Rules, Regulations, and Reforms
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  • Article

Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting

By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
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  • 26 Mar 2019
  • First Look

New Research and Ideas, March 26, 2019

case:https://hbsp.harvard.edu/product/516005-PDF-ENG Harvard Business School Case 218-107 The TARP Bailouts: Saving the Banking and Automotive Industries Comparison of the... View Details
Keywords: Dina Gerdeman
  • November 2020
  • Supplement

Improving Access at VA (Update)

By: Ryan W. Buell
In November 2020, Chief Veterans Experience Officer, Lynda Davis, and Deputy Chief Veterans Experience Officer, Barbara C. Morton reflect on a busy four years leading the Veterans Experience Office at the U.S. Department of Veterans Affairs. The case provides an update... View Details
Keywords: Government; Service Management; Leading Change; Transformation; Service Operations; Management; Health Care and Treatment; Government Administration; Performance Improvement; Public Administration Industry; United States
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  • 29 Sep 2008
  • Research & Ideas

Financial Crisis Caution Urged by Faculty Panel

Harvard Business School faculty members, looking at the U.S. financial crisis from a variety of disciplines, urged caution and prudent analysis in a recent panel discussion.... View Details
Keywords: by Martha Lagace; Financial Services
  • 14 Mar 2017
  • First Look

First Look at New Research, March 14

https://cb.hbsp.harvard.edu/cbmp/product/516023-PDF-ENG Harvard Business School Case 817-083 thredUP: Think Secondhand First In the fall of 2016, the management team at... View Details
Keywords: Sean Silverthorne
  • 26 May 2015
  • First Look

First Look: May 26

http://hrleadsbusiness.org/rise-of-hr-e-book May 2015 JAMA, the Journal of the American Medical Association Medicine's Continuous Improvement Imperative By: Huckman, Robert S., and Ananth Raman Abstract—... View Details
Keywords: Sean Silverthorne
  • 22 Jul 2008
  • First Look

First Look: July 22, 2008

goals has different effects on performance. This paper reports on a longitudinal study of 23 neonatal intensive care units (NICUs) in a structured, quality-improvement program. We test View Details
Keywords: Martha Lagace

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