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      • January 2024 (Revised April 2024)
      • Case

      Target Malaria: Editing Mosquitoes through Gene Drives

      By: Shikhar Ghosh and Shweta Bagai
      Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details
      Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa
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      Ghosh, Shikhar, and Shweta Bagai. "Target Malaria: Editing Mosquitoes through Gene Drives." Harvard Business School Case 824-068, January 2024. (Revised April 2024.)
      • 2024
      • Working Paper

      The Wandering Scholars: Understanding the Heterogeneity of University Commercialization

      By: Josh Lerner, Henry Manley, Carolyn Stein and Heidi Williams
      University-based scientific research has long been argued to be a central source of commercial innovation and economic growth. Yet at the same time, there have been long-held concerns that many university-based discoveries never realize their potential social... View Details
      Keywords: Research; Higher Education; Business Startups; Innovation and Invention
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      Lerner, Josh, Henry Manley, Carolyn Stein, and Heidi Williams. "The Wandering Scholars: Understanding the Heterogeneity of University Commercialization." Harvard Business School Working Paper, No. 24-043, January 2024. (Econometrica, Conditionally Accepted. Earlier version distributed as National Bureau of Economic Research Working Paper No. 31898 and Harvard Business School Working Paper No. 24-043. Related discussion published as “The Commercialisation of University Research: The Role of People versus Place,” VoxEU, 2024.)
      • January 2024 (Revised May 2024)
      • Case

      Generation Investment Management: Sustainable Investing in a Warming World

      By: Vikram S. Gandhi, Michael Norris and David Allen
      In September 2021, the sustainable investment firm Generation Investment Management (Generation) considered whether to add Schneider Electric to the focus list of companies in which it was prepared to invest. Dedicated to promoting a sustainable world through its... View Details
      Keywords: Sustainable Investing; Climate Change; Environmental Sustainability; Governance; Private Equity; Public Equity; Financial Markets; Investment Return; Investment Activism; Investment Funds; Investment Portfolio; Institutional Investing; Corporate Social Responsibility and Impact; Financial Services Industry; United Kingdom; England; London
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      Gandhi, Vikram S., Michael Norris, and David Allen. "Generation Investment Management: Sustainable Investing in a Warming World." Harvard Business School Case 324-043, January 2024. (Revised May 2024.)
      • 2024
      • Article

      Financial Constraints and Short-Term Planning Are Linked to Flood Risk Adaptation Gaps in U.S. Cities

      By: Shirley Lu and Anya Nakhmurina
      Adaptation is critical in reducing the inevitable impact of climate change. Here we study cities’ adaptation to elevated flood risk by introducing a linguistic measure of adaptation extracted from financial disclosures of 431 US cities over 2013–2020. While cities with... View Details
      Keywords: City; Natural Disasters; Climate Change; Adaptation; Risk and Uncertainty; Strategic Planning
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      Lu, Shirley, and Anya Nakhmurina. "Financial Constraints and Short-Term Planning Are Linked to Flood Risk Adaptation Gaps in U.S. Cities." Art. 43. Communications Earth & Environment 5 (2024).
      • January 2024
      • Case

      Flashfood: The Magic of Commitment

      By: Reza Satchu and Patrick Sanguineti
      Josh Domingues had accomplished what countless young entrepreneurs long to achieve: founding a promising company that aspires to make the world a tangibly better place. Shocked to learn that international food waste cumulatively amounted to the world’s third largest... View Details
      Keywords: Entrepreneur; Founder; Startup; Business Model; Business Startups; Food; Applications and Software; Mission and Purpose; Environmental Sustainability; Canada
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      Satchu, Reza, and Patrick Sanguineti. "Flashfood: The Magic of Commitment." Harvard Business School Case 824-131, January 2024.
      • January 11, 2024
      • Article

      Understanding the Tradeoffs of the Amazon Antitrust Case

      By: Chiara Farronato, Andrey Fradkin, Andrei Hagiu and Dionne Lomax
      Regulators in the United States and Europe have been taking on Big Tech, challenging what they say are the companies’ anti-competitive and predatory strategies that harm consumers and third-party users of their platforms. This article examines the FTC’s case against... View Details
      Keywords: Monopoly; Governing Rules, Regulations, and Reforms; Market Design; Lawsuits and Litigation
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      Farronato, Chiara, Andrey Fradkin, Andrei Hagiu, and Dionne Lomax. "Understanding the Tradeoffs of the Amazon Antitrust Case." Harvard Business Review Digital Articles (January 11, 2024).
      • January 2024 (Revised February 2024)
      • Course Overview Note

      Managing Customers for Growth: Course Overview for Students

      By: Eva Ascarza
      Managing Customers for Growth (MCG) is a 14-session elective course for second-year MBA students at Harvard Business School. It is designed for business professionals engaged in roles centered on customer-driven growth activities. The course explores the dynamics of... View Details
      Keywords: Customer Relationship Management; Decision Making; Analytics and Data Science; Growth Management; Telecommunications Industry; Technology Industry; Financial Services Industry; Education Industry; Travel Industry
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      Ascarza, Eva. "Managing Customers for Growth: Course Overview for Students." Harvard Business School Course Overview Note 524-032, January 2024. (Revised February 2024.)
      • January 2024
      • Technical Note

      The ICARUS Principles: What It Takes to Tackle the World

      By: Debora L. Spar and Julia M. Comeau
      Over the course of the 20th century, most of the world’s major multinational corporations framed their mission around Milton Friedman’s famous mantra: that the sole purpose of the firm is to maximize its shareholders’ profits. Recently, however, growing numbers of... View Details
      Keywords: Purpose; Mission; Social Business; Corporate Social Responsibility and Impact; Mission and Purpose; Social Enterprise; For-Profit Firms
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      Spar, Debora L., and Julia M. Comeau. "The ICARUS Principles: What It Takes to Tackle the World." Harvard Business School Technical Note 324-055, January 2024.
      • January 2024 (Revised May 2024)
      • Case

      PortageBay and ESG Analytics

      By: Vikram S. Gandhi and Radhika Kak
      In 2023, sustainable investors faced several challenges. The first was the lack of access to standardized and vetted environmental, social, and governance (ESG) data, and equally, the interpretation of this data into investment-useful insights. Reducing reliance on... View Details
      Keywords: ESG Ratings; Investment Funds; Governance; Environmental Sustainability; Corporate Social Responsibility and Impact
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      Gandhi, Vikram S., and Radhika Kak. "PortageBay and ESG Analytics." Harvard Business School Case 324-065, January 2024. (Revised May 2024.)
      • January 2024 (Revised February 2024)
      • Technical Note

      Computer Science for Strategists

      By: Andy Wu and Matt Higgins
      Two of the most important computer science principles in the technology industry are abstraction and platformization. Our aim with this note is to explain these concepts in an approachable way that brings managers and computer scientists a little closer together. View Details
      Keywords: Strategist; Computer Science; Strategy; Management Practices and Processes
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      Wu, Andy, and Matt Higgins. "Computer Science for Strategists." Harvard Business School Technical Note 724-429, January 2024. (Revised February 2024.)
      • January 2024
      • Article

      Helping Children Catch Up: Early Life Shocks and the PROGRESA Experiment

      By: Achyuta Adhvaryu, Theresa Molina, Anant Nyshadham and Jorge Tamayo
      Can investing in children who faced adverse events in early childhood help them catch up? We answer this question using two orthogonal sources of variation – resource availability at birth (local rainfall) and cash incentives for school enrollment – to identify the... View Details
      Keywords: Children; Outcome or Result; Welfare; Early Childhood Education; Weather
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      Adhvaryu, Achyuta, Theresa Molina, Anant Nyshadham, and Jorge Tamayo. "Helping Children Catch Up: Early Life Shocks and the PROGRESA Experiment." Economic Journal 134, no. 657 (January 2024): 1–22.
      • 2024
      • Working Paper

      Lost in Transmission

      By: Thomas Graeber, Shakked Noy and Christopher Roth
      For many decisions, people rely on information received from others by word of mouth. How does the process of verbal transmission distort economic information? In our experiments, participants listen to audio recordings containing economic forecasts and are paid to... View Details
      Keywords: Information Trnasmission; Word Of Mouth; Word-of-Mouth; Narratives; Reliability; Knowledge Sharing; Spoken Communication; Cognition and Thinking
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      Graeber, Thomas, Shakked Noy, and Christopher Roth. "Lost in Transmission." Harvard Business School Working Paper, No. 24-047, January 2024.
      • 2024
      • Article

      Technological Adoption and Taxation: The Case of China's Golden Tax Reform

      By: Haichao Fan, Yu Liu, Nancy Qian and Jaya Y. Wen
      This paper investigates the effect of Phase 2 of the Golden Tax Project on VAT in China. The reform introduced computer-generated invoices and electronic transaction linking. Using a difference-in-differences strategy, we show that the reform increased VAT by reducing... View Details
      Keywords: Taxation; Governing Rules, Regulations, and Reforms; Technological Innovation; Economic Growth; China
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      Fan, Haichao, Yu Liu, Nancy Qian, and Jaya Y. Wen. "Technological Adoption and Taxation: The Case of China's Golden Tax Reform." Tax Policy and the Economy 38 (2024): 101–122.
      • 2024
      • Report

      The Eco-Digital EraTM: The Dual Transition to a Sustainable and Digital Economy

      By: Suraj Srinivasan, Andy Feinstein, Amol Khadikar, Jiani Zhang, Noémie Lauer, Hiral Shah, Sally Epstein, Jerome Buvat and Vaishnavee Ananth
      Since the proliferation of smartphones and social media in the late 2000s, digital has captured an increasingly large portion of the economy. In this Capgemini Research Institute report, The Eco-Digital EraTM: The dual transition to a sustainable and... View Details
      Keywords: Technology Adoption; Digital Transformation; Environmental Sustainability; Trends
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      Srinivasan, Suraj, Andy Feinstein, Amol Khadikar, Jiani Zhang, Noémie Lauer, Hiral Shah, Sally Epstein, Jerome Buvat, and Vaishnavee Ananth. "The Eco-Digital EraTM: The Dual Transition to a Sustainable and Digital Economy." Report, Capgemini Research Institute, January 2024.
      • 2024
      • Book

      The Everything Token: How NFTs and Web3 Will Transform the Way We Buy, Sell, and Create

      By: Steve Kaczynski and Scott Duke Kominers
      We demystify the coming digital revolution, showing how NFTs will transform our online and offline interactions.

      NFTs aren’t just pictures on the internet, or a fad that has come and gone. Rather, they’re a new technology for creating digital assets and... View Details
      Keywords: Economic Systems; Microeconomics; Entrepreneurship; Cultural Entrepreneurship; Information Technology; Innovation and Invention; Innovation Strategy; Digital Platforms; Digital Strategy; Digital Transformation; Internet and the Web; Technology Adoption; Marketing; Marketing Strategy; Product Marketing; Product Positioning; Markets; E-commerce; Market Design; Value; Customer Value and Value Chain; Collaborative Innovation and Invention; Innovation and Management; Organizational Structure; Customer Ownership; Ownership; Advertising Industry; Communications Industry; Computer Industry; Consumer Products Industry; Fashion Industry; Information Technology Industry; Media and Broadcasting Industry; Technology Industry; Web Services Industry
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      Kaczynski, Steve, and Scott Duke Kominers. The Everything Token: How NFTs and Web3 Will Transform the Way We Buy, Sell, and Create. Portfolio/Penguin, 2024.
      • 2024
      • Chapter

      The Private Economy Under Party-State Capitalism

      By: Margaret M. Pearson, Meg Rithmire and Kellee S. Tsai
      This chapter addresses the evolution of China’s approach to the private sector from the early reform era until the beginning of Xi Jinping’s third term. It argues that China has evolved from a familiar form of state capitalism, in which economic growth is the primary... View Details
      Keywords: Government Administration; International Relations; Economic Growth; Economic Sectors; Economic Systems; China
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      Pearson, Margaret M., Meg Rithmire, and Kellee S. Tsai. "The Private Economy Under Party-State Capitalism." Chap. 3 in Chinese Politics: The Xi Jinping Difference. 2nd edition edited by Stanley Rosen and Daniel C. Lynch, 67–82. Routledge, 2024.
      • December 2023 (Revised March 2024)
      • Case

      Manufacturing Moderna's Future

      By: Satish Tadikonda and William Marks
      In 2019, Moderna faced long odds of survival having failed to develop a successful clinical program out of the vast platform technology they had built around mRNA. Nearly overnight, the company skyrocketed to success with a vaccine for COVID-19, leading to an extremely... View Details
      Keywords: Health Pandemics; Health Testing and Trials; Technological Innovation; Product Development; Production; Science-Based Business; Biotechnology Industry
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      Tadikonda, Satish, and William Marks. "Manufacturing Moderna's Future." Harvard Business School Case 824-076, December 2023. (Revised March 2024.)
      • 2025
      • Working Paper

      Money, Time, and Grant Design

      By: Kyle Myers and Wei Yang Tham
      We conduct survey experiments to test how the design of scientific grants— the money and time awarded—can be used to manage researchers. On average, researchers are relatively unwilling to trade off money for time when choosing among grants. However, there is... View Details
      Keywords: Research; Power and Influence; Money
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      Myers, Kyle, and Wei Yang Tham. "Money, Time, and Grant Design." Harvard Business School Working Paper, No. 24-037, December 2023. (Revised June 2025.)
      • 2025
      • Working Paper

      Enhancing Treatment Effect Prediction on Privacy-Protected Data: An Honest Post-Processing Approach

      By: Ta-Wei Huang and Eva Ascarza
      As firms increasingly rely on customer data for personalization, concerns over privacy and regulatory compliance have grown. Local Differential Privacy (LDP) offers strong individual-level protection by injecting noise into data before collection. While... View Details
      Keywords: Targeted Intervention; Conditional Average Treatment Effect Estimation; Differential Privacy; Honest Estimation; Post-processing; Analytics and Data Science; Consumer Behavior; Marketing
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      Huang, Ta-Wei, and Eva Ascarza. "Enhancing Treatment Effect Prediction on Privacy-Protected Data: An Honest Post-Processing Approach." Harvard Business School Working Paper, No. 24-034, December 2023. (Revised March 2025.)
      • December 2023
      • Case

      Raízen: Helping to Decarbonize the World?

      By: Gunnar Trumbull, Pedro Levindo, Daniel Tong and Rafaella Mazza
      Raízen, the world’s largest sugar and ethanol producer, strived to find ways to expand the second-generation ethanol (E2G) market, which it pioneered. The company planned to invest R$24 billion (around $4.6 billion) in 20 production plants, with a total capacity to... View Details
      Keywords: Plant-Based Agribusiness; Factories, Labs, and Plants; Renewable Energy; Environmental Sustainability; Production; Expansion; Agriculture and Agribusiness Industry; Energy Industry; Brazil; Europe; North America; United States; Argentina; Paraguay
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      Trumbull, Gunnar, Pedro Levindo, Daniel Tong, and Rafaella Mazza. "Raízen: Helping to Decarbonize the World?" Harvard Business School Case 724-014, December 2023.
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