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      • 2025
      • Working Paper

      Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how Computed Tomography (CT) scanners - that combine Xrays and computers to image soft tissues of the brain and other organs -- have become a widely used diagnostic tool. Specifically, we chronicle the 1) initial development of CT... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-004, July 2019. (Revised January 2025.)
      • 2025
      • Working Paper

      Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how endoscopy transformed the diagnosis of ulcers, cancerous polyps, and other alimentary canal diseases and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber endoscopes... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-005, July 2019. (Revised January 2025.)
      • 2025
      • Working Paper

      HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-007, July 2019. (Revised January 2025.)
      • 2024
      • Working Paper

      Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances

      By: Amar Bhidé, Caitlin N. Bowler and Srikant M. Datar
      We describe how operations through laparoscopes – tubular instruments inserted into abdominal cavities – revolutionized gynecological and other surgeries inside the abdomen, such as gall bladder removal. Specifically, we chronicle the 1) foundational contributions of... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Caitlin N. Bowler, and Srikant M. Datar. "Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-008, July 2019. (Revised May 2024.)
      • 2025
      • Working Paper

      Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances

      By: Srikant M. Datar, Amar Bhidé and Katherine Stebbins
      This case history describes how Magnetic Resource Imaging (MRI) came to complement – and partially replace -- computed tomography (CT) imaging of soft tissue. Specifically, we chronicle 1) the development of foundational techniques and prototypes (through the 1970s);... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Datar, Srikant M., Amar Bhidé, and Katherine Stebbins. "Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-001, July 2019. (Revised January 2025.)
      • 2025
      • Working Paper

      Mammography - Early Detection, Precise Diagnoses: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how the development of x-ray-based techniques and equipment (“mammography”) led to widespread screening for breast cancer and enabled “minimally invasive” biopsies of breast tumors. Specifically, we chronicle how: 1) new protocols and... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Mammography - Early Detection, Precise Diagnoses: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-002, July 2019. (Revised January 2025.)
      • 2025
      • Working Paper

      Ultrasound Imaging--Cheap, Versatile, and Safe: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how efforts on multiple fronts, including advocacy, training, and technological development, made ultrasound the second most commonly used diagnostic imaging technology (after X-rays). Specifically, we chronicle 1) ultrasound’s development... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Ultrasound Imaging--Cheap, Versatile, and Safe: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-003, July 2019. (Revised January 2025.)
      • July 2019
      • Case

      Autonomous Vehicles: Smooth or Bumpy Ride Ahead?

      By: Elie Ofek and Akhil Waghmare
      In early 2019, transportation was set to undergo a major transformation with the advent of autonomous vehicles (AVs), also referred to as driverless cars, which were nearing completion from an R&D and testing phase. Yet many questions remained open regarding exactly... View Details
      Keywords: Transportation; Technological Innovation; Disruptive Innovation; Transformation; Technology Adoption; Business Model; Governing Rules, Regulations, and Reforms; Transportation Industry; Auto Industry
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      Ofek, Elie, and Akhil Waghmare. "Autonomous Vehicles: Smooth or Bumpy Ride Ahead?" Harvard Business School Case 520-008, July 2019.
      • June 2019
      • Teaching Note

      Zebra Medical Vision

      By: Shane Greenstein and Sarah Gulick
      Teaching note is meant to accompany Zebra Medical Vision case, which offers a look at a company’s decisions as a small startup competing with other startups and major technology companies. It also demonstrates the challenges faced by a machine learning company working... View Details
      Keywords: Business Startups; Science-Based Business; Applications and Software; Patents; Cross-Cultural and Cross-Border Issues; Health Care and Treatment; Technology Industry; Technology Industry; Technology Industry; Israel
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      Greenstein, Shane, and Sarah Gulick. "Zebra Medical Vision." Harvard Business School Teaching Note 619-053, June 2019.
      • June 2019
      • Case

      The Shale Revolution: America's Energy Independence?

      By: Richard H.K. Vietor and Howaida Kamel
      The shale revolution has upended oil and gas markets for nearly a decade and has positioned the U.S. to become a net energy exporter by 2020. Technological improvements pushed productivity forward which has had positive overall positive affects for the U.S. economy.... View Details
      Keywords: Shale Oil; Shale Gas; LNG; Energy Policy; Drilling Technology; Energy; Trade; Economics; Macroeconomics; Policy; Energy Industry; Manufacturing Industry; United States; Middle East
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      Vietor, Richard H.K., and Howaida Kamel. "The Shale Revolution: America's Energy Independence?" Harvard Business School Case 719-076, June 2019.
      • May 28, 2019
      • Other Article

      How Russia Found a Disinformation Haven in America

      By: Rawi Abdelal and Galit Goldstein
      The Mueller Report established that “the Russians” undertook information operations campaigns to meddle in the 2016 U.S. presidential election. Though this has been clear for a long time, Americans continue to discuss Russian information operations in the wrong way.... View Details
      Keywords: Elections; Donald Trump; Political Elections; National Security; Information Technology; Governing Rules, Regulations, and Reforms; Social Media; Russia; United States
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      Abdelal, Rawi, and Galit Goldstein. "How Russia Found a Disinformation Haven in America." National Interest (May 28, 2019).
      • 2019
      • Working Paper

      The Gift of Global Talent: Innovation Policy and the Economy

      By: William R. Kerr
      Talent is the most precious resource for today’s knowledge-based economy, and a significant share of the U.S. skilled workforce in technology fields is foreign born. The United States has long held a leading position in attracting global talent, but the gap to other... View Details
      Keywords: Global Talent Flows; Talent and Talent Management; Global Range; Immigration; Policy; Economy
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      Kerr, William R. "The Gift of Global Talent: Innovation Policy and the Economy." Harvard Business School Working Paper, No. 19-116, May 2019.
      • May 2019 (Revised September 2019)
      • Case

      Mobike and ofo: Dancing with Titans (A)

      By: Shikhar Ghosh and Haibo Zhao
      This case address pacing issues – how fast does a company need to scale? It also examines the role of investors in determining company strategy and exit.
      Mobike and ofo were two dominant players in China’s emerging dockless bike-sharing market, that allowed users... View Details
      Keywords: Information Technology; Venture Capital; Financing and Loans; Competition; Value Creation; Governance; Economics; Business Startups; Strategy; Business Exit or Shutdown; Entrepreneurship; Infrastructure; Transportation; Bicycle Transportation; China
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      Ghosh, Shikhar, and Haibo Zhao. "Mobike and ofo: Dancing with Titans (A)." Harvard Business School Case 819-135, May 2019. (Revised September 2019.)
      • Summer 2019
      • Article

      The Plight of the Graying Tech Worker

      By: William R. Kerr
      If you’re in tech and over 40, your experience is probably underappreciated. A global talent pool complicates matters. View Details
      Keywords: Employees; Age; Personal Development and Career; Immigration; Policy; Technology Industry; Technology Industry
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      Kerr, William R. "The Plight of the Graying Tech Worker." MIT Sloan Management Review 60, no. 4 (Summer 2019): 12–13.
      • 2019
      • Working Paper

      Biometric Monitoring, Service Delivery and Misreporting: Evidence from Healthcare in India

      By: Thomas Bossuroy, Clara Delavallade and Vincent Pons
      Developing countries increasingly use biometric identification technology in hopes of improving the reliability of administrative information and delivering social services more efficiently. This paper exploits the random placement of biometric tracking devices in... View Details
      Keywords: Biometric Technology; Health Care and Treatment; Technological Innovation; Analytics and Data Science; Quality; Performance Improvement; India
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      Bossuroy, Thomas, Clara Delavallade, and Vincent Pons. "Biometric Monitoring, Service Delivery and Misreporting: Evidence from Healthcare in India." NBER Working Paper Series, No. 26388, October 2019. (Revise and resubmit requested, Review of Economics and Statistics.)
      • 2019
      • Chapter

      International Business and Emerging Markets in Historical Perspective

      By: Geoffrey Jones
      This chapter examines international business in emerging markets over the long run. It shows how the strategies of Western multinationals evolved over time. In the first era of globalization in the 19th century, Western firms sought access to resources, and they faced... View Details
      Keywords: Emerging Markets; Business History; Multinational Firms and Management; Globalization
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      Jones, Geoffrey. "International Business and Emerging Markets in Historical Perspective." Chap. 3 in The Oxford Handbook of Management in Emerging Markets, edited by Robert Grosse and Klaus E. Meyer, 55–76. Oxford, UK: Oxford University Press, 2019.
      • 2019
      • Working Paper

      Labor Market Shocks and the Demand for Trade Protection: Evidence from Online Surveys

      By: Rafael Di Tella and Dani Rodrik
      We study preferences for government action in response to layoffs resulting from different types of labor-market shocks. We consider the following shocks: technological change, a demand shift, bad management, and three kinds of international outsourcing. Respondents... View Details
      Keywords: Labor; Markets; System Shocks; Trade; Attitudes; Surveys
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      Di Tella, Rafael, and Dani Rodrik. "Labor Market Shocks and the Demand for Trade Protection: Evidence from Online Surveys." NBER Working Paper Series, No. 25705, March 2019.
      • 2020
      • Working Paper

      Overcoming the Cold Start Problem of CRM Using a Probabilistic Machine Learning Approach

      By: Eva Ascarza
      The success of Customer Relationship Management (CRM) programs ultimately depends on the firm's ability to understand consumers' preferences and precisely capture how these preferences may differ across customers. Only by understanding customer heterogeneity, firms can... View Details
      Keywords: Customer Management; Targeting; Deep Exponential Families; Probabilistic Machine Learning; Cold Start Problem; Customer Relationship Management; Customer Value and Value Chain; Consumer Behavior; Analytics and Data Science; Mathematical Methods; Retail Industry
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      Padilla, Nicolas, and Eva Ascarza. "Overcoming the Cold Start Problem of CRM Using a Probabilistic Machine Learning Approach." Harvard Business School Working Paper, No. 19-091, February 2019. (Revised May 2020. Accepted at the Journal of Marketing Research.)
      • February 2019 (Revised January 2022)
      • Case

      The U.S. – China Trade War

      By: Alberto Cavallo, Mariana Cal and Anne Laski
      On December 1, 2018, U.S. President Donald Trump and China’s Leader Xi Jinping faced each other across a dinner table during a G20 meeting in Buenos Aires, Argentina. After what Trump called an “amazing and productive meeting,” the two leaders announced a truce in the... View Details
      Keywords: Trade War; Trump; Current Account; NAFTA; Balance Of Payments; Intellectual Property Protection; Trade; Macroeconomics; Economic Slowdown and Stagnation; International Relations; United States; China
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      Cavallo, Alberto, Mariana Cal, and Anne Laski. "The U.S. – China Trade War." Harvard Business School Case 719-034, February 2019. (Revised January 2022.)
      • February 2019 (Revised September 2019)
      • Case

      Theranos: The Unicorn That Wasn't

      By: Joseph B. Fuller and John Masko
      In 2003, 19-year-old Elizabeth Holmes founded a startup dedicated to making blood testing easier and more affordable. By 2015, her company, Theranos, was worth $9 billion. It boasted a star-studded board and contracts with national pharmacy and supermarket chains... View Details
      Keywords: Theranos; Blood; Lab Testing; Fraud; Holmes; Balwani; Shultz; Carreyrou; Securities And Exchange Commission; Food And Drug Administration; FDA; SEC; Health Testing and Trials; Corporate Accountability; Organizational Culture; Misleading and Fraudulent Advertising; Crime and Corruption; Entrepreneurship; Medical Devices and Supplies Industry
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      Fuller, Joseph B., and John Masko. "Theranos: The Unicorn That Wasn't." Harvard Business School Case 319-068, February 2019. (Revised September 2019.)
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