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- All HBS Web
(1,742)
- People (10)
- News (377)
- Research (1,013)
- Multimedia (6)
- Faculty Publications (451)
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- 2024
- Working Paper
Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for
millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s
development; the initial development of tamoxifen from 1960 to 1973;... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant Datar, and Katherine Stebbins. "Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-134, July 2020. (Revised May 2024.)
- 2014
- Case
Tommy Koh and the United States–Singapore Free Trade Agreement (B)
By: James K. Sebenius and Laurence A. Green
This case details the efforts of Singapore Ambassador-At-Large Tommy Koh to forge a free trade agreement between Singapore and the United States following both nations' support for the initiation of negotiations on a USSFTA. Examining the various barriers and fronts of... View Details
Sebenius, James K., and Laurence A. Green. "Tommy Koh and the United States–Singapore Free Trade Agreement (B)." Program on Negotiation at Harvard Law School Case, 2014.
- 2013
- Article
Boardroom Centrality and Firm Performance
By: David F. Larcker, Eric C. So and Charles C.Y. Wang
Firms with central or well-connected boards of directors earn superior risk-adjusted stock returns. Initiating a long position in the most central firms and a short position in the least central firms earns an average risk-adjusted return of 4.68% per year. Firms with... View Details
Larcker, David F., Eric C. So, and Charles C.Y. Wang. "Boardroom Centrality and Firm Performance." Journal of Accounting & Economics 55, nos. 2-3 (April–May 2013): 225–250.
- 29 Jan 2015
- Op-Ed
The Fall of Greece
them by favoring reform based on central government control rather than the forces of competition, meritocracy, and individual accountability. Let me be clear about one thing: the previous government, as most previous governments, failed... View Details
Keywords: by George Serafeim
- 08 Jun 2010
- First Look
First Look: June 8
for reuse is highlighted. The case recounts Kundra's experience at the state and local government levels in developing open data initiatives and the application of that experience to the federal government.... View Details
Keywords: Martha Lagace
- July 2009 (Revised January 2014)
- Case
Sustainability at Millipore
By: Michael W. Toffel and Katharine Lee
This case describes Millipore Corporation's approach to becoming a more environmentally sustainable company. As he prepared for his quarterly meeting with the CEO, the Director of Sustainability needed to develop positions on several issues. Tactically, he needed to... View Details
Keywords: Investment; Corporate Disclosure; Operations; Corporate Social Responsibility and Impact; Organizational Structure; Natural Environment; Environmental Sustainability; Pollutants
Toffel, Michael W., and Katharine Lee. "Sustainability at Millipore." Harvard Business School Case 610-012, July 2009. (Revised January 2014.) (defining sustainability in a corporate context, managing greenhouse gas (GHG) emissions including inventories, targets, disclosure, reduction strategies.)
- 14 Mar 2007
- Op-Ed
Government’s Misguided Probe of Private Equity
Fifty-three years ago, Judge Harold Medina dismissed charges brought by the Justice Department against seventeen leading investment banks. A case built up over a decade of investigations and almost three years of trial collapsed when the View Details
- 15 Feb 2011
- First Look
First Look: Feb. 15
each complementing the other. Government Advertising and Media Coverage of Corruption Scandals Authors:Rafael Di Tella and Ignacio Franceschelli Publication:American Economic Journal: Applied Economics (forthcoming) Abstract : We... View Details
Keywords: Sean Silverthorne
- September 1995
- Case
Richina Capital Partners Limited
By: William A. Sahlman and Jason Green
Richard Yan and Suzanne Foels raise a $52.5 million fund to invest in Chinese companies in concert with major multinational companies. They face all the challenges of starting a business from scratch in addition to the challenges of operating in a cross-cultural... View Details
Keywords: Business Startups; Venture Capital; Problems and Challenges; Emerging Markets; Multinational Firms and Management; Cross-Cultural and Cross-Border Issues; Governance Compliance; Business Strategy; Expansion; Investment Return; China
Sahlman, William A., and Jason Green. "Richina Capital Partners Limited." Harvard Business School Case 396-059, September 1995.
- 2024
- Working Paper
Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how Computed Tomography (CT) scanners - that combine Xrays
and computers to image soft tissues of the brain and other organs -- have become a widely used
diagnostic tool. Specifically, we chronicle the 1) initial development of CT... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-004, July 2019. (Revised May 2024.)
- 10 Mar 2015
- First Look
First Look: March 10
http://www.hbs.edu/faculty/Publication%20Files/15-068_c417331e-2146-40b6-8dfc-aa9a029db119.pdf February 2015 Harvard Business Review Corporate Governance 2.0 By: Subramanian, Guhan Abstract—No abstract available. Publisher's link:... View Details
Keywords: Carmen Nobel
- 22 Apr 2009
- Working Paper Summaries
Where is the Pharmacy to the World? International Regulatory Variation and Pharmaceutical Industry Location
- 16 Nov 2010
- First Look
First Look: November 16, 2010
reassignments (transfers) across posts of varying importance to control bureaucrats. High-skilled bureaucrats face less frequent political transfers and lower variability in the importance of their posts. We find evidence of two alternative paths to career success:... View Details
Keywords: Sean Silverthorne
- July 2021
- Case
Amazon HQ2
By: James K. Sebenius and Ben Cook
Amazon’s failed bid for a second headquarters location (“HQ2”) in Long Island City, New York offers many lessons for negotiators looking to avoid similar high-profile defeats in strategically important deals. The company’s project – which promised to bring billions of... View Details
Keywords: Buildings and Facilities; Negotiation; Public Opinion; Governing Rules, Regulations, and Reforms; Problems and Challenges
Sebenius, James K., and Ben Cook. "Amazon HQ2." Harvard Business School Case 922-009, July 2021.
- January 2018
- Case
Trian Partners' Proxy Contest at Procter & Gamble
By: Suraj Srinivasan and Quinn Pitcher
In July 2017, activist hedge fund Trian Partners announced that it was launching a proxy fight at U.S. consumer goods giant Procter & Gamble. P&G would be the largest company ever subjected to a proxy fight, as Trian sought to have its CEO, Nelson Peltz, elected to the... View Details
- January 2025 (Revised March 2025)
- Case
Creating Value by Splitting Aster: Can One Minus One Equal Two?
By: V.G. Narayanan and Kairavi Dey
Aster DM Healthcare (Aster), founded by Dr. Azad Moopen in 1987, is a prominent healthcare conglomerate with operations spanning hospitals, clinics, retail pharmacies, and diagnostic centers across India and the GCC. After its 2018 listing on India’s National Stock... View Details
Keywords: Corporate Governance; Corporate Accountability; Leadership; Change Management; Mergers and Acquisitions; Restructuring; Negotiation; Valuation; Health Industry; Asia; India; Middle East; United Arab Emirates
Narayanan, V.G., and Kairavi Dey. "Creating Value by Splitting Aster: Can One Minus One Equal Two?" Harvard Business School Case 125-069, January 2025. (Revised March 2025.)
- January 2013 (Revised October 2015)
- Case
Pittsburgh
By: Eric Werker, Meg Rithmire, Benjamin Kennedy and Andrew Knauer
The case narrates the development of Pittsburgh from the 1940s to 2012. It analyzes the collapse of the steel industry in the early 1980s, the city's subsequent decline, and the city's later re-emergence as a hub for higher education, the tech sector, and the... View Details
Keywords: Google; Population; City Growth; Shale; PNC; Tom Murphy; Luke Ravenstahl; Public-private Partnership; Tax Increment Financing; Brownfields; Renaissance; Industry Clusters; Industry Growth; City; Business and Government Relations; Taxation; Philanthropy and Charitable Giving; Nonprofit Organizations; Higher Education; Technology Industry; Health Industry; Steel Industry; Education Industry; Pittsburgh
Werker, Eric, Meg Rithmire, Benjamin Kennedy, and Andrew Knauer. "Pittsburgh." Harvard Business School Case 713-035, January 2013. (Revised October 2015.)
- September 2006 (Revised December 2006)
- Case
Arizona Department of Public Health: The Challenges of Preparing for a Public Health Emergency
By: Lynda M. Applegate, Ajay Vinze, T. S. Raghu and Minu Ipe
In the post-9/11 era information technology enablement for emergency preparedness and response have taken on increased significance. Public health organizations like ADHS play a critical role in any statewide preparation for large scale emergencies. With issues like... View Details
Keywords: Problems and Challenges; Information Technology; Health Care and Treatment; Business Processes; Service Delivery; National Security; Health Industry; Public Administration Industry; Arizona
Applegate, Lynda M., Ajay Vinze, T. S. Raghu, and Minu Ipe. "Arizona Department of Public Health: The Challenges of Preparing for a Public Health Emergency." Harvard Business School Case 807-016, September 2006. (Revised December 2006.)
- December 2018 (Revised June 2020)
- Case
Creating the French Behavioral Insights Team
By: Michael Luca, Ariella Kristal and Emilie Billaud
This case explores how neuroscientist Mariam Chammat helped set up the first behavioral insights team at the center of the French government, and encouraged French administrations to innovate and create policy initiatives based on psychological theories of influence... View Details
Keywords: Choice Architecture; Behavioral Economics; Experiments; Negotiation; Decision Making; Economics; Taxation; Entrepreneurship; Consumer Behavior; Public Administration Industry; Europe; France; Paris
Luca, Michael, Ariella Kristal, and Emilie Billaud. "Creating the French Behavioral Insights Team." Harvard Business School Case 919-015, December 2018. (Revised June 2020.)
- 31 Jan 2022
- Research & Ideas
Where Can Digital Transformation Take You? Insights from 1,700 Leaders
for instance, in innovation labs designed for that purpose. 6. Ethical decision-making and proactive governance As technological advances give rise to previously unimaginable use cases, digitally mature organizations recognize that they... View Details