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- January–February 2023
- Article
Data-Driven COVID-19 Vaccine Development for Janssen
By: Dimitris Bertsimas, Michael Lingzhi Li, Xinggang Liu, Jennings Xu and Najat Khan
The COVID-19 pandemic has spurred extensive vaccine research worldwide. One crucial part of vaccine development is the phase III clinical trial that assesses the vaccine for safety and efficacy in the prevention of COVID-19. In this work, we enumerate the first... View Details
- 2 Mar 2023 - 4 Mar 2023
- Conference Presentation
Ethical Risks of Autonomous Products: The Case of Mental Health Crises on AI Companion Applications
By: Julian De Freitas, K. Uguralp and Z. Oguz
- 2023
- Working Paper
Job Design and Workers’ Wellbeing: Evidence from a Hospital Setting
By: Susanna Gallani and Jacob Riegler
This study examines the relationship between job design imbalance and workers’ well-being. We build on Simons (2005) framework for the design of high-performing jobs and develop a survey instrument to capture workers’ perceptions of their job design and work... View Details
- 26 Oct 2023 - 28 Oct 2023
- Conference Presentation
The Dark Side of Generative AI: Chatbots and Mental Health
By: Julian De Freitas, K Uguralp, Z Oguz and Stefano Puntoni
- December 2022 (Revised September 2024)
- Case
Sword Health
By: Regina E. Herzlinger, Annelena Lobb and Carin-Isabel Knoop
Virgilio “V” Bento, CEO of Sword Health—a startup that provided virtual physical therapy to patients in self-insured firms via AI and sensor technology with supervision by a physical therapist with a doctorate—considered how to increase its U.S. market share. To do so,... View Details
- December 2022 (Revised December 2024)
- Exercise
Choose Your Own Adventure: Your Financial Health (B): 5 Years Later, What Now?
By: Sara L. Fleiss and Emily R. McComb
- December 2022
- Article
Collaborative Rooming: An Innovative Pilot Project to Overcome Primary Care Challenges
By: Gagandeep Singh, Jill G. Lenhart, Richard A. Helmers, Michele Renee Eberlee, Heather Costley, Joel B. Roberts and Robert S. Kaplan
Primary care physicians are overburdened with growing complexities and increasing expectations for primary care visits. To meet expectations, primary care physicians must multitask during visits and spend extra hours in the office for charting, billing, and... View Details
- December 2022
- Article
Cost Standard Set Program: Moving Forward to Standardization of Cost Assessment Based on Clinical Condition
By: Anna Paula Beck da Silva Etges, Richard D. Urman, Anne Geubelle, Robert Kaplan and Carisi Anne Polanczyk
This communication announces the International Cost Standard Set Program. Its goal is to establish global standardized frameworks for measuring the costs of treating specific clinical conditions. A scientific committee, including 16 international healthcare cost... View Details
- Winter 2022
- Article
Distributing a Billion Vaccines: COVAX Successes, Challenges, and Opportunities
By: Eric Budish, Hannah Kettler, Scott Duke Kominers, Erik Osland, Canice Prendergast and Andrew A. Torkelson
By January 2022, the COVAX international vaccine collaboration had allocated over a billion vaccines to over 140 countries. We describe and review the allocation process chosen, which reflected both an objective of equitably distributing vaccines across the world and... View Details
- 2022
- Article
Investigating the Association Between Telemedicine Use and Timely Follow-Up Care After Acute Cardiovascular Hospital Encounters
By: Mitchell Tang, A Jay Holmgren, Erin E. McElrath, Ankeet S. Bhatt, Anubodh S. Varshney, Simin Gharib Lee, Muthiah Vaduganathan, Dale S. Adler and Robert S. Huckman
Background: Telemedicine use increased dramatically during the COVID-19 pandemic; however, questions remain as to how telemedicine use impacts care.
Objectives: The purpose of this study was to examine the association of increased telemedicine use on rates of... View Details
Objectives: The purpose of this study was to examine the association of increased telemedicine use on rates of... View Details
- December 2022
- Article
The Contribution of Price Growth to Pharmaceutical Revenue Growth in the United States: Evidence from Medicines Sold in Retail Pharmacies
By: Pragya Kakani, Michael Chernew and Amitabh Chandra
Context: To what extent does pharmaceutical revenue growth depend on new medicines versus increasing prices for existing medicines? Moreover, does using list prices, as is commonly done, instead of prices net of confidential rebates offered by manufacturers, which are... View Details
- Winter 2022
- Article
Vaccines and the COVID-19 Pandemic: Lessons from Failure and Success
By: Scott Duke Kominers and Alex Tabarrok
The losses from the global COVID-19 pandemic have been staggering—trillions in economic costs, on top of significant losses of life, health, and well-being. The world made significant and successful investments in vaccines to mitigate the pandemic, yet there were... View Details
- November 2022 (Revised March 2024)
- Case
Replika AI: Monetizing a Chatbot
By: Julian De Freitas and Nicole Tempest Keller
In early 2018, Eugenia Kuyda, co-founder and CEO of San Francisco-based chatbot Replika AI, was deciding how to monetize the app she had built. Launched in 2017, Replika was a consumer AI “companion app” developed by a team of AI software engineers originally based in... View Details
- November 2022
- Case
Ajax Health: A New Model for Medical Technology Innovation
By: Regina E. Herzlinger and Ben Creo
This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
- November 2022
- Case
The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales
By: Regina E. Herzlinger and Tiffany Farrell
Can an online, direct-to-consumer pharmacy both improve the quality and speed of care for patients who need branded drugs and stabilize profits for pharmaceutical manufacturers? UpScript, after years spent achieving legal and regulatory compliance and simultaneous... View Details
- November 2022 (Revised December 2022)
- Exercise
Choose Your Own Adventure: Your Financial Health (A): Congratulations, HBS Grad! Now, What?
By: Sara Fleiss and Emily R. McComb
- November 2022 (Revised April 2024)
- Case
Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams
By: Debora L. Spar and Julia M. Comeau
In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At the time, there was little medication... View Details
- 2022
- Article
How Does Working from Home during COVID-19 Affect What Managers Do? Evidence from Time-Use Studies
By: Thomaz Teodorovicz, Raffaella Sadun, Andrew L. Kun and Orit Shaer
We assess how the sudden and widespread shift to working from home during the pandemic impacted how managers allocate time throughout their working day. We analyze the results from an online time-use survey with data on 1,192 knowledge workers (out of which 973 are... View Details
Keywords: Time-use; Working-from-home; COVID; Managers; Knowledge Workers; Health Pandemics; Time Management
- November 2022
- Article
Measuring Inequality beyond the Gini Coefficient May Clarify Conflicting Findings
By: Kristin Blesch, Oliver P. Hauser and Jon M. Jachimowicz
Prior research has found mixed results on how economic inequality is related to various outcomes. These contradicting findings may in part stem from a predominant focus on the Gini coefficient, which only narrowly captures inequality. Here, we conceptualize the... View Details
- November 1, 2022
- Article
To Prepare for Future Surges, U.S. Hospitals Must Start Planning—& Sharing Resources—Now!
Keywords: COVID-19; Crisis Management; Health Pandemics; Disruption; Planning; Health Industry; United States