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      • 2020
      • Working Paper

      Tech Clusters

      By: William R. Kerr and Frederic Robert-Nicoud
      Tech clusters like Silicon Valley play a central role for modern innovation, business competitiveness, and economic performance. This paper reviews what constitutes a tech cluster, how they function internally, and the degree to which policy makers can purposefully... View Details
      Keywords: Clusters; Agglomeration; Innovation; Industry Clusters; Innovation and Invention; Entrepreneurship; Patents
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      Kerr, William R., and Frederic Robert-Nicoud. "Tech Clusters." Harvard Business School Working Paper, No. 20-063, November 2019. (Revised June 2020.)
      • November 2019 (Revised January 2020)
      • Case

      Bayer Crop Science

      By: David E. Bell, Damien McLoughlin, Natalie Kindred and James Barnett
      In mid-2019, a year after German conglomerate Bayer Group closed its acquisition of U.S.-based seeds giant Monsanto, the leadership of Bayer’s Crop Science division (which absorbed Monsanto) is reflecting on the opportunities ahead. Some observers have questioned... View Details
      Keywords: Agribusiness; Research and Development; Innovation and Invention; Innovation Strategy; Mergers and Acquisitions; Consolidation; Customer Value and Value Chain; Change Management; Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry; United States; Germany
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      Bell, David E., Damien McLoughlin, Natalie Kindred, and James Barnett. "Bayer Crop Science." Harvard Business School Case 520-055, November 2019. (Revised January 2020.)
      • October 14, 2019
      • Article

      The Truth About Open Offices: There Are Reasons Why They Don't Produce the Desired Interactions

      By: Ethan Bernstein and Ben Waber
      It’s never been easier for workers to collaborate—or so it seems. Open, flexible, activity-based spaces are displacing cubicles, making people more visible. Messaging is displacing phone calls, making people more accessible. Enterprise social media such as Slack and... View Details
      Keywords: Buildings and Facilities; Interpersonal Communication; Communication Technology; Design; Human Resources; Performance Productivity; Organizational Design
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      Bernstein, Ethan, and Ben Waber. "The Truth About Open Offices: There Are Reasons Why They Don't Produce the Desired Interactions." Harvard Business Review 97, no. 6 (November–December 2019): 82–91.
      • October 2019
      • Case

      Feeling Machines: Emotion AI at Affectiva

      By: Shane Greenstein and John Masko
      In 2016, Affectiva—a Boston-based emotion AI software company with a long track record of building emotion-sensing software for market research—had attempted to expand into new verticals by releasing a mobile software development kit (SDK) that downloaders could adapt... View Details
      Keywords: Artificial Intelligence; Market Research; Business Model; Finance; Revenue; Decision Making; Risk and Uncertainty; Market Entry and Exit; Applications and Software; AI and Machine Learning; Information Technology Industry; Information Technology Industry; United States
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      Greenstein, Shane, and John Masko. "Feeling Machines: Emotion AI at Affectiva." Harvard Business School Case 620-058, October 2019.
      • October 2019 (Revised April 2020)
      • Background Note

      Note on Funding Deep Tech Startups

      By: Karim Lakhani, Peter Barrett and Noubar Afeyan
      This Background Note provides essential information on funding deep technologies—those technologies that were inherently capital intensive, time consuming, risky, and potentially disruptive. Both dilutive and non-dilutive sources of investment are highlighted, along... View Details
      Keywords: Entrepreneurship; Energy; Venture Capital; Corporate Finance; Initial Public Offering; Investment; Health Testing and Trials; Innovation and Invention; Technological Innovation; Intellectual Property; Product Design; Product Development; Information Technology; Research and Development; Risk and Uncertainty; Technology Industry; Technology Industry; United States; North America; Europe; Asia
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      Lakhani, Karim, Peter Barrett, and Noubar Afeyan. "Note on Funding Deep Tech Startups." Harvard Business School Background Note 620-029, October 2019. (Revised April 2020.)
      • September 2019 (Revised February 2020)
      • Teaching Note

      Fishbowl: Scaling Up

      By: Leslie K. John
      Email mking@hbs.edu for a courtesy copy.

      Teaching Note for HBS No. 919-013. Fishbowl is a social media app that allows professionals to connect with other relevant professionals both within their company and... View Details
      Keywords: Communication Technologies; Customer Value; Value Chain; Interpersonal Communication; Talent and Talent Management; Customer Value and Value Chain; Entrepreneurship; Business Model; Growth and Development Strategy; Marketing Strategy; Advertising; Product Marketing; Digital Platforms; Consumer Behavior; Network Effects; Emotions; Motivation and Incentives; Trust; Applications and Software; Technology Adoption; Digital Platforms; Media and Broadcasting Industry; Media and Broadcasting Industry; Media and Broadcasting Industry; Media and Broadcasting Industry; Media and Broadcasting Industry; United States
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      John, Leslie K. "Fishbowl: Scaling Up." Harvard Business School Teaching Note 920-022, September 2019. (Revised February 2020.) (Email mking@hbs.edu for a courtesy copy.)
      • Article

      Improving the Rhythm of Your Collaboration

      By: Ethan S. Bernstein, Jesse Shore and David Lazer
      In this article, we summarize our research on the value of intermittency for complex problem solving at work and give practical advice on how organizations can improve the rhythm of their people's collaboration. Executives have been counseled to be collaborative... View Details
      Keywords: Problem Solving; Collaborative Innovation and Invention; Internet and the Web; Leadership
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      Bernstein, Ethan S., Jesse Shore, and David Lazer. "Improving the Rhythm of Your Collaboration." MIT Sloan Management Review 61, no. 1 (Fall 2019).
      • 2018
      • Article

      Prior Ties and the Limits of Peer Effects on Startup Team Performance

      By: Sharique Hasan and Rembrand Koning
      We conduct a field experiment at an entrepreneurship bootcamp to investigate whether interaction with proximate peers shapes a nascent startup team's performance. We find that teams whose members lack prior ties to others at the bootcamp experience peer effects that... View Details
      Keywords: Field Experiment; Peer Effects; Office Space; Knowledge Spillovers; Accelerators; Entrepreneurship; Knowledge Sharing; Performance; Technology Industry; India
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      Hasan, Sharique, and Rembrand Koning. "Prior Ties and the Limits of Peer Effects on Startup Team Performance." Strategic Management Journal 40, no. 9 (September 2019): 1394–1416.
      • September 2019
      • Article

      Technology Reemergence: Creating New Value for Old Technologies in Swiss Mechanical Watchmaking, 1970-2008

      By: Ryan Raffaelli
      In 1983, 14 years after the introduction of the battery-powered quartz watch, mechanical watches and the Swiss watchmakers who built them were predicted to be obsolete (Landes, 1983). Unexpectedly, however, by 2008 the Swiss mechanical watchmaking industry had... View Details
      Keywords: Technology Reemergence; Technology Cycles; Cognition And Market Redefinition; Legacy Technology Trajectories; Information Technology; Demand and Consumers; Organizational Change and Adaptation; Identity; Change; Consumer Products Industry; Switzerland
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      Raffaelli, Ryan. "Technology Reemergence: Creating New Value for Old Technologies in Swiss Mechanical Watchmaking, 1970-2008." Administrative Science Quarterly 64, no. 3 (September 2019): 576–618.
      • August 2019 (Revised April 2021)
      • Case

      Zillow Offers: Winning Online Real Estate 2.0

      By: Luis Viceira, Marco Di Maggio and Allison Ciechanover
      Founded in 2005, Zillow had become the leading online real estate and home-related marketplace. The brand was recognized as a trusted resource for players in the real estate market, providing information and transparency on home prices. Revenue, which was historically... View Details
      Keywords: Real Estate; Corporate Culture; Intermediation; Brokerage; Startup; Evaluating Business Investments; Property; Information Technology; Business Model; Expansion; Business Startups; Media and Broadcasting Industry; Media and Broadcasting Industry; United States
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      Viceira, Luis, Marco Di Maggio, and Allison Ciechanover. "Zillow Offers: Winning Online Real Estate 2.0." Harvard Business School Case 220-021, August 2019. (Revised April 2021.)
      • Article

      Extending the Role of Headquarters Beyond the Firm Boundary: Entrepreneurial Alliance Innovation

      By: Jaeho Kim and Andy Wu
      Prior research on corporate headquarters (CHQ) characteristics identifies the impact of CHQ location and composition on the innovation outcomes of internal subsidiaries. However, given that external strategic alliances with high-tech entrepreneurial firms represent a... View Details
      Keywords: Alliance; Innovation; Corporate Headquarters; Geographic Proximity; Entrepreneurship; Corporate Strategy; Alliances; Joint Ventures; Innovation and Invention; Business Headquarters; Geographic Location
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      Kim, Jaeho, and Andy Wu. "Extending the Role of Headquarters Beyond the Firm Boundary: Entrepreneurial Alliance Innovation." Art. 15. Special Issue on Corporate Headquarters. Journal of Organization Design 8 (2019): 1–35.
      • 2019
      • Article

      History, Micro Data, and Endogenous Growth

      By: Ufuk Akcigit and Tom Nicholas
      The study of economic growth is concerned with long-run changes, and therefore, historical data should be especially influential in informing the development of new theories. In this review, we draw on the recent literature to highlight areas in which study of history... View Details
      Keywords: Economic Development; Growth; Innovation; Economic Growth; History; Analytics and Data Science; Innovation and Invention
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      Akcigit, Ufuk, and Tom Nicholas. "History, Micro Data, and Endogenous Growth." Annual Review of Economics 11 (2019): 615–633.
      • 2025
      • Working Paper

      Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how a chance discovery of bacteria that infect stomach linings completely changed how physicians treat ulcers. Specifically, we chronicle how: 1) two Australian physicians brought the bacterial infection to the world’s attention and... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-006, July 2019. (Revised January 2025.)
      • 2025
      • Working Paper

      HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-007, July 2019. (Revised January 2025.)
      • July 2019 (Revised November 2019)
      • Case

      Osaro: Picking the Best Path

      By: William R. Kerr, James Palano and Bastiane Huang
      The founder of Osaro saw the potential of deep reinforcement learning to allow robots to be applied to new applications. Osaro targeted warehousing, already a dynamic industry for robotics and automation, for its initial product—a system which would allow robotic arms... View Details
      Keywords: Artificial Intelligence; Machine Learning; Robotics; Robots; Ecommerce; Fulfillment; Warehousing; AI; Startup; Technology Commercialization; Business Startups; Entrepreneurship; Logistics; Order Taking and Fulfillment; Information Technology; Commercialization; Learning; Complexity; Competition; E-commerce
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      Kerr, William R., James Palano, and Bastiane Huang. "Osaro: Picking the Best Path." Harvard Business School Case 820-012, July 2019. (Revised November 2019.)
      • May 2019
      • Case

      Elon Musk's Big Bets Update, 2019

      By: David B. Yoffie and Daniel Fisher
      This short case provides an update to Elon Musk's strategy and tactical moves with Tesla, Solar City, and SpaceX from 2016-2019. View Details
      Keywords: Electric Vehicles; Batteries; Solar Power; Execution; Space Flight; Tesla; SolarCity; SpaceX; Elon Musk; Information Technology; Risk and Uncertainty; Expansion; Renewable Energy; Strategy; Investment; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry
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      Yoffie, David B., and Daniel Fisher. "Elon Musk's Big Bets Update, 2019." Harvard Business School Case 719-512, May 2019.
      • March 2019 (Revised May 2019)
      • Case

      Fetchr: A New Way of Last Mile Delivery

      By: V.G. Narayanan and Eren Kuzucu
      By mid-2016, five years of aggressive growth had transformed Fetchr from a small logistics startup to a 1,000-employee, full-fledged last-mile delivery company operating across four countries in the Middle East and North Africa (MENA). Already beneficiaries of the... View Details
      Keywords: Startup; Decision; Financial Strategy; UAE; KSA; MENA; Cost Accounting; Business Model; Business Startups; Transformation; Cost Management; Strategy; Disruptive Innovation; Technological Innovation; Growth and Development Strategy; Growth Management; Logistics; Service Delivery; Supply Chain Management; Performance Evaluation; Mathematical Methods; Mobile and Wireless Technology; Transportation Networks; Middle East; United Arab Emirates; Dubai; Bahrain; Egypt; Saudi Arabia; North Africa
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      Narayanan, V.G., and Eren Kuzucu. "Fetchr: A New Way of Last Mile Delivery." Harvard Business School Case 119-018, March 2019. (Revised May 2019.)
      • March 2019
      • Case

      DayTwo: Going to Market with Gut Microbiome

      By: Ayelet Israeli and David Lane
      DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
      Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B2C; B2B Vs. B2C; Health & Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; "USA,"; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Technology Industry; Technology Industry; Technology Industry; Technology Industry; Technology Industry; Israel; United States
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      Israeli, Ayelet, and David Lane. "DayTwo: Going to Market with Gut Microbiome." Harvard Business School Case 519-010, March 2019.
      • February 2019 (Revised August 2019)
      • Case

      KangaTech

      By: Karim R. Lakhani, Patrick J. Ferguson, Sarah Fleischer, Jin Hyun Paik and Steven Randazzo
      On a warm January afternoon in 2019, Steve Saunders, Dave Scerri, Carl Dilena, and Nick Haslam (see Exhibit 1 for biographies), co-founders of KangaTech, wrapped up the latest round of discussions about the future direction of their sports-technology start-up. Focused... View Details
      Keywords: Startup; Technology Commercialization; Prototype; Business Startups; Technological Innovation; Sports; Health; Commercialization; Research and Development; Decision Making; Growth and Development Strategy; Technology Industry; Technology Industry; Technology Industry; Australia
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      Lakhani, Karim R., Patrick J. Ferguson, Sarah Fleischer, Jin Hyun Paik, and Steven Randazzo. "KangaTech." Harvard Business School Case 619-049, February 2019. (Revised August 2019.)
      • 2020
      • Working Paper

      Overcoming the Cold Start Problem of CRM Using a Probabilistic Machine Learning Approach

      By: Eva Ascarza
      The success of Customer Relationship Management (CRM) programs ultimately depends on the firm's ability to understand consumers' preferences and precisely capture how these preferences may differ across customers. Only by understanding customer heterogeneity, firms can... View Details
      Keywords: Customer Management; Targeting; Deep Exponential Families; Probabilistic Machine Learning; Cold Start Problem; Customer Relationship Management; Customer Value and Value Chain; Consumer Behavior; Analytics and Data Science; Mathematical Methods; Retail Industry
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      Padilla, Nicolas, and Eva Ascarza. "Overcoming the Cold Start Problem of CRM Using a Probabilistic Machine Learning Approach." Harvard Business School Working Paper, No. 19-091, February 2019. (Revised May 2020. Accepted at the Journal of Marketing Research.)
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