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2008
Article

Entrepreneurial Ventures and Whole-body Donations: A Regional Perspective from the United States

By: Michel Anteby and Mikell Hyman

Human cadavers are crucial to medical science. While the debate on how to secure sufficient cadavers has focused primarily on donors' behaviors, procuring organizations' roles in increasing donations remain less explored. The United States offers a unique setting in... View Details

Keywords: Entrepreneurship; Behavior; Programs; Nonprofit Organizations; Business Ventures; Health Testing and Trials; Demand and Consumers; Supply Chain; For-Profit Firms; Organizations; Training; United States

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July 2006 (Revised July 2007)
Case

C.K. Coolidge, Inc. (Abridged)

Coolidge (CKC), a chemical manufacturer, is being sued for patent infringement. The plaintiffs are the patent holder and its sole licensee, who is also a CKC competitor. An analyst at CKC has done a breakeven decision analysis from CKC's perspective, balancing going to... View Details

Keywords: Negotiation Preparation; Courts and Trials; Patents; Analysis; Decision Choices and Conditions; Lawsuits and Litigation; Chemical Industry

Fall 2020
Article

Sizing Up Corporate Restructuring in the COVID Crisis

By: Robin Greenwood, Benjamin Iverson and David Thesmar

In the wake of the COVID-19 pandemic, the financial and legal system will need to deal with a surge of financial distress in the business sector. Some firms will be able to survive, while others will face bankruptcy and thus need to be liquidated or reorganized. Many... View Details

Keywords: COVID-19; Health Pandemics; Economy; System Shocks; Financial Crisis; Restructuring

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Health; Biotechnology; Pharmaceutical; Medical Devices & Supplies

28 Oct 2024
Op-Ed

Latino Voters Have Grown More Politically Divided. That’s Not Surprising.

vehicles—political parties fight for votes where they can get them. If a group of voters starts to grow, then both parties will court that group with campaign effort, messaging, and policy change. And, in... View Details

Keywords: by Richard Calvo, Vincent Pons, and Jesse M. Shapiro

19 May 2016
Research Event

Crowdsourcing, Patent Trolls, and Other Research Insights Highlighted at Harvard Business School Symposium

dispute to court can be an expensive proposition. Cohen shared an example: Lumen View Technology, which had initiated patent lawsuits in the past against numerous companies, sued FindTheBest and several... View Details

Keywords: by Dina Gerdeman & Carmen Nobel

March 2015 (Revised February 2022)
Supplement

CV Ingenuity (B): Epilogue

By: Regina E. Herzlinger and Andrew Otazo

Duke Rohlen used a lea-nfunding, iconoclastic strategy for his start up for a drug eluding balloon for peripheral artery disease. His giant competitors were first movers. Did Duke obtain the funding he sought? How did his DEB fare versus that of his competitors? The... View Details

September 2001
Background Note

Note on Application of the Antitrust Laws to the New Economy: An Analysis of United States v. Microsoft Corporation

Analyzes the 1991 decision of the U.S. Court of Appeals for the District of Columbia Circuit in the seminal New Economy antitrust case United States vs. Microsoft Corp., 253 F.3rd 34 (D.C. Cir. 2001), which arose out of Microsoft's efforts to promote Internet Explorer... View Details

Keywords: Lawsuits and Litigation; Software; Intellectual Property; Monopoly; Laws and Statutes; Information Technology Industry; District of Columbia

2006
Chapter

BioRisk: interleukin-2 from laboratory to market in the United States and Germany

By: Arthur A. Daemmrich

Keywords: Product Development; Risk and Uncertainty; Health Testing and Trials; Pharmaceutical Industry; Biotechnology Industry; United States; Germany

November 2009 (Revised August 2010)
Case

NovoCure Ltd.

By: William A. Sahlman and Sarah Flaherty

Venture capitalist William Doyle must raise $35 million for a portfolio company with a promising, novel cancer therapy, just as global capital markets are imploding in the fall of 2008. NovoCure, Ltd., has developed an electrical-field-based therapy, called Tumor... View Details

Keywords: Financial Crisis; Entrepreneurship; Venture Capital; Investment; Health Care and Treatment; Health Testing and Trials; Technological Innovation; Financial Services Industry

April 2003 (Revised October 2004)
Case

Novartis: The Challenge of Success (B)

By: Sandra J. Sucher and Stacy McManus

When Dr. Daniel Vasella learned of the early Phase 1 trial results, he immediately decided what course of action Novartis would take. Students will be able to examine and assess the concrete steps, and the rationale behind them, that Novartis took in response to this... View Details

Keywords: Decision Making; Moral Sensibility; Innovation and Invention; Distribution; Product Development; Production; Problems and Challenges; Research and Development; Biotechnology Industry; Pharmaceutical Industry

Article

The Impact of Intangibles on Firm Growth

By: Stefano Denicolai, E. Cotta Ramusino and F. Sotti

Persuading users to try new technologies continues to be a problem confronting organisations and technology vendors alike. To better understand the process of new technology trial and adoption, several theoretical models have been proposed, of which the Technology... View Details

Keywords: Motivation and Incentives; Technology Adoption

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Article

Decisions about Medication Use and Cancer Screening across Age Groups in the United States

By: Kathleen M. Fairfield, Bethany S. Gerstein, Carrie A. Levin, Vickie Stringfellow, Heidi Wierman and Mary McNaughton-Collins

Objective
To describe decision process and quality for common cancer screening and medication decisions by age group.

Methods
We included 2941 respondents to a national Internet survey who made at least one decision about colorectal, breast,... View Details

Keywords: Screening; Decision Making; Health Care and Treatment; Health Testing and Trials

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13 Oct 2015
Research & Ideas

Does Business Get Done the Same Way in Emerging and Developed Countries?

because the legal system and independent courts pressure government to be even handed. Q: Are there common traits among successful leaders in emerging markets? Are the executive skillsets they need to... View Details

Keywords: by Sean Silverthorne

July 2011 (Revised September 2012)
Case

Intraoperative Radiotherapy for Breast Cancer (A)

"This trial is going to take longer." Those were words that Michael Kaschke, CEO of Carl Zeiss AG, was not surprised to hear as he nurtured the intraoperative radiotherapy business inside his company's microsurgery unit. But he also didn't expect it to take 13 years to... View Details

Keywords: Finance; Business History; Disruptive Innovation; Emerging Markets; Organizational Change and Adaptation; Research and Development; Safety

November 2009 (Revised March 2010)
Case

Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon

In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details

Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States

November 2020
Teaching Note

DayTwo: Going to Market with Gut Microbiome

By: Ayelet Israeli

Teaching Note for HBS Case No. 519-010. DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals.... View Details

2010
Case

Playa Dorado

By: W. Earl Sasser

Playa Dorada Beach & Resort in Boca Raton, Florida, faces a growing seasonal demand for tennis services. The number of guests is expected to double in the next few years, and while the tennis facilities are a popular and well-promoted amenity at the resort, court space... View Details

Keywords: Demand and Consumers; Management Analysis, Tools, and Techniques; Expansion; Planning; Mathematical Methods; Price; Profit; Sales; Operations; Growth and Development Strategy; Marketing; Performance Capacity; Accommodations Industry; Florida

2008
Chapter

The Evidence Does Not Speak for Itself: Expert Witnesses and the Organization of DNA-Typing Companies

By: Arthur A. Daemmrich

During the past 15 years, new biotechnology companies have promoted DNA typing as a sophisticated criminal and paternity identification technique. Private testing laboratories produce results that link individuals with crime scenes and fathers to their children.... View Details

Keywords: Governing Rules, Regulations, and Reforms; Courts and Trials; Organizational Structure; Practice; Genetics; Science-Based Business; Trust; Commercialization; Vertical Integration

12 Aug 2019
Working Paper Summaries

Case Histories of Significant Medical Advances

Keywords: by Amar Bhidé, Srikant M. Datar, and Katherine Stebbins

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