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  • 09 Dec 2008
  • First Look

First Look: December 9, 2008

roles that various constituencies played in the development process. Purchase the case: http://harvardbusinessonline.hbsp.harvard.edu/ b01/en/common/item_detail.jhtml?id=207027 Note on Accountability in the U.S. Health View Details
Keywords: Martha Lagace
  • 24 Apr 2018
  • First Look

First Look at New Research and Ideas, April 24, 2018

In October 2015, ZappRx founder Zoe Barry is deciding between two business models for her health technology start-up. Her product, a software application that aims to expedite the prescription fulfillment process for patients with rare... View Details
Keywords: Sean Silverthorne
  • September 2021 (Revised October 2022)
  • Supplement

Hester Pharmaceuticals (B): Securing Supply

By: Dante Roscini and John Masko
Supplements the (A) case. In late 2020, demand for Hester Pharmaceutical’s (Hester’s) breakthrough oncology drug Akrozumab was outstripping the company’s most optimistic projections. In order to increase manufacturing capacity and meet the demand, Hester was... View Details
Keywords: COVID-19 Pandemic; Cost vs Benefits; Trade; Supply Chain; Global Strategy; Buildings and Facilities; Operations; Health Care and Treatment; Demand and Consumers; Global Range; Globalized Markets and Industries; Pharmaceutical Industry; Italy; China; United States; Germany
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Roscini, Dante, and John Masko. "Hester Pharmaceuticals (B): Securing Supply." Harvard Business School Supplement 722-009, September 2021. (Revised October 2022.)
  • 15 Sep 2015
  • First Look

September 15, 2015

https://www.hbs.edu/faculty/Pages/item.aspx?num=49614 October 2015 Journal of Finance The Cost of Capital for Alternative Investments By: Jurek, Jakub W., and Erik Stafford Abstract—Traditional risk factor models indicate that hedge funds... View Details
Keywords: Sean Silverthorne
  • 2025
  • Working Paper

Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Fabio Villa
We describe how Coronary Artery Bypass Grafting (CABG, or more popularly, “bypass”) operations revolutionized the treatment of coronary disease (that can produce fatal heart attacks and debilitating angina). Specifically, we chronicle the: 1) development of the... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Fabio Villa. "Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-010, July 2019. (Revised January 2025.)
  • 11 Oct 2024
  • Research & Ideas

How AI Could Ease the Refugee Crisis and Bring New Talent to Businesses

instance, Paulson says she recently had a conversation with an executive MBA student who is designing a platform for matching patients with mental health care providers and wanted to learn from the... View Details
Keywords: by Ben Rand; Technology; Information Technology
  • 24 Sep 2001
  • Research & Ideas

How To Be an Angel Investor

evaluation occurs throughout sourcing, valuing, structuring and negotiating. Given the potential time drain, the best angel investors are careful and strategic in their approach to evaluation. Angels take a variety of approaches to this... View Details
Keywords: by David Amis & Howard Stevenson
  • 12 Mar 2014
  • Research & Ideas

Entrepreneurship and Multinationals Drive Globalization

War I, the management of political risk became a central concern for firms operating internationally. These risks were on many levels, from expropriation to exchange controls and other economic policies. The issue is explored in multiple chapters, but the chapter on... View Details
Keywords: by Sean Silverthorne; Beauty & Cosmetics; Manufacturing; Consumer Products; Pharmaceutical
  • 21 Oct 2008
  • First Look

First Look: October 21, 2008

http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=608168 HealthAllies (A) Harvard Business School Case 302-019 This case describes a "do good and do well" firm that enables individuals to buy health View Details
Keywords: Martha Lagace
  • 2024
  • Working Paper

Cephalosporins—Fighting Hospital Infections: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins
This case history describes the development of three generations of cephalosporins – antibiotics that have significantly reduced hospital infections. Specifically, we chronicle how: 1) Early (pre-cephalosporin) antibiotics were developed in the first half of the 20th... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant Datar, and Katherine Stebbins. "Cephalosporins—Fighting Hospital Infections: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-133, July 2020. (Revised May 2024.)
  • 2025
  • Working Paper

Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s development; the initial development of tamoxifen from 1960 to 1973;... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant Datar, and Katherine Stebbins. "Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-134, July 2020. (Revised January 2025.)
  • 2025
  • Working Paper

Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Caitlin N. Bowler
We describe how operations through laparoscopes – tubular instruments inserted into abdominal cavities – revolutionized gynecological and other surgeries inside the abdomen, such as gall bladder removal. Specifically, we chronicle the 1) foundational contributions of... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Caitlin N. Bowler. "Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-008, July 2019. (Revised January 2025.)
  • 2025
  • Working Paper

Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how Computed Tomography (CT) scanners - that combine Xrays and computers to image soft tissues of the brain and other organs -- have become a widely used diagnostic tool. Specifically, we chronicle the 1) initial development of CT... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-004, July 2019. (Revised January 2025.)
  • Spring 2021
  • Article

Corporate Resilience and Response During COVID-19

By: Alex Cheema-Fox, Bridget LaPerla, George Serafeim and Hui (Stacie) Wang
The coronavirus pandemic caused a sharp market decline while raising heterogeneous responses across companies related to their employees, supply chain, and repurposing of operations to provide needed products and services. We study whether during the 2020 COVID-19... View Details
Keywords: ESG; COVID-19; Coronavirus; Crisis Response Plans; Crisis; ESG (Environmental, Social, Governance) Performance; ESG Ratings; Leadership & Corporate Accountability; Big Data; Machine Learning; Investor Behavior; Institutional Investors; Corporate Performance; Health Pandemics; Crisis Management; Corporate Social Responsibility and Impact; Human Capital; Supply Chain; Operations; Leadership; Corporate Accountability; Institutional Investing; Performance
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Cheema-Fox, Alex, Bridget LaPerla, George Serafeim, and Hui (Stacie) Wang. "Corporate Resilience and Response During COVID-19." Journal of Applied Corporate Finance 33, no. 2 (Spring 2021): 24–40.
  • 19 Jul 2006
  • Research & Ideas

Political Turmoil and Mexico’s Economy

maintained his control in part by creating a banking system that functioned more as a kind of investment club, Maurer says. Local businessmen would agree to lend each other money to finance one another's companies, while also selling... View Details
Keywords: by Julia Hanna
  • 28 May 2012
  • Research & Ideas

A Pragmatic Alternative for Creating a Corporate Social Responsibility Strategy

treating its employees well. The company provides staffers with free education services to complete high school and supplementary medical care to cover gaps in government health plans. These efforts have... View Details
Keywords: by Dina Gerdeman
  • March 2013 (Revised May 2013)
  • Case

Omar Ishrak: Building Medtronic Globally

By: Bill George and Natalie Kindred
Omar Ishrak, Medtronic's first non-American CEO, aims to reinvigorate the medical device maker's growth by focusing on emerging markets, therapy innovation, and creative business models. In 2012, budget constraints in mature economies, the lack of new medical therapies... View Details
Keywords: Healthcare; Medical Devices; Medtronic; Globalization; Innovation; Reverse Innovation; Leadership; Multinational Firms and Management; Globalized Markets and Industries; Management Teams; Business Model; Emerging Markets; Global Strategy; Health Care and Treatment; Acquisition; Innovation and Invention; Manufacturing Industry; Medical Devices and Supplies Industry; China
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George, Bill, and Natalie Kindred. "Omar Ishrak: Building Medtronic Globally." Harvard Business School Case 413-065, March 2013. (Revised May 2013.)
  • 11 Dec 2012
  • First Look

First Look: Dec. 11

of Health Care Reform Oberholzer-Gee, Felix, Raffaella Sadun, and Richard G. HamermeshHarvard Business School Case 711-403 Per the Patient Protection and Affordable Care Act... View Details
Keywords: Sean Silverthorne
  • 30 Jun 2015
  • First Look

First Look: June 30, 2015

associated with adult outcomes at home. Sons raised by an employed mother spend more time caring for family members than men whose mothers stayed home full time, and daughters raised by an employed mother spend less time on housework than... View Details
Keywords: Carmen Nobel
  • January 2009 (Revised July 2010)
  • Case

iZumi

By: Robert F. Higgins, Jacob Ian Broder-Fingert, Eliot Sherman and Sidhartha Palani
Presents the issues faced while building an innovative company in an emerging space with new intellectual property from the perspective of a venture capitalist. Beth Seidenberg, a partner at the venture capital firm Kleiner Perkins Caufield & Byers (KPCB), had helped... View Details
Keywords: Entrepreneurship; Venture Capital; Globalized Markets and Industries; Innovation and Management; Intellectual Property; Rights; Genetics; Health Industry; Health Industry
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Higgins, Robert F., Jacob Ian Broder-Fingert, Eliot Sherman, and Sidhartha Palani. "iZumi." Harvard Business School Case 809-105, January 2009. (Revised July 2010.)
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