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- All HBS Web
(5,754)
- People (17)
- News (2,102)
- Research (2,744)
- Events (3)
- Multimedia (223)
- Faculty Publications (2,098)
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- 15 Aug 2017
- First Look
First Look at New Research and Ideas, August 15, 2017
2017 Washington, DC: American Public Health Association Public Health Preparedness: Case Studies in Policy and Management By: Howitt, Arnold M., Dutch Leonard, and David W. Giles, eds. Abstract—This book... View Details
Keywords: Sean Silverthorne
- 18 Aug 2009
- First Look
First Look: August 18
students in the EC course, "Competing Through Business Models." Purchase this course overview : http://cb.hbsp.harvard.edu/cb/product/710409-PDF-ENG Dartmouth-Hitchcock Medical Center: Spine Care Harvard Business School Case... View Details
Keywords: Martha Lagace
- 2025
- Working Paper
Prozac—Controversial Blockbuster: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes the development of Prozac, a blockbuster drug that transformed
the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we
chronicle the: 1) prior treatments for depression and the research that... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Prozac—Controversial Blockbuster: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-135, July 2020. (Revised January 2025.)
- 2025
- Working Paper
Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how endoscopy transformed the diagnosis of ulcers, cancerous polyps, and other alimentary canal diseases and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber endoscopes... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-005, July 2019. (Revised January 2025.)
- 30 Apr 2013
- First Look
First Look: April 30
longitudinal data from 68 multi-method case studies of organizational change initiatives conducted at the National Health Service in the United Kingdom support these predictions and advance a relational view of organizational change in... View Details
Keywords: Sean Silverthorne
- September 2009 (Revised September 2010)
- Case
Avid Radiopharmaceuticals and Lighthouse Capital Partners
By: Matthew Rhodes-Kropf and Ann Leamon
In fall 2008, a venture lender must decide whether to make a loan to Avid, a small but promising venture-backed life sciences firm. In reviewing her proposal, Cristy Barnes considers the company's characteristics and how they differ from a typical investment. At the... View Details
Keywords: Business Startups; Decision Choices and Conditions; Financial Crisis; Venture Capital; Private Equity; Financing and Loans; Investment; Health Industry; Health Industry
Rhodes-Kropf, Matthew, and Ann Leamon. "Avid Radiopharmaceuticals and Lighthouse Capital Partners." Harvard Business School Case 810-054, September 2009. (Revised September 2010.)
- 13 Apr 2015
- Research & Ideas
3 Ways Firms Can Profit From Environmental Investments
strategy has less than a 50 percent probability of panning out. "What sustainability analysis does is to really make [executives] stop and think," she says. "'Will consumers start to care about this? Will we face new regulatory pressures?... View Details
- 14 Jun 2016
- First Look
June 14, 2016
challenging work environments. This article focuses on two such contexts—health care and education. The authors theorize differences in psychological safety based on work type, hierarchical status, and leadership effectiveness. Consistent... View Details
Keywords: Sean Silverthorne
- 28 Aug 2017
- Research & Ideas
Should Industry Competitors Cooperate More to Solve World Problems?
example here. More business leaders in the health care sector recognize that industry actors that engage in egregious pricing of drugs bring all kinds of problems to the whole industry. Silverthorne: You... View Details
- 01 May 2020
- In Practice
COVID-19’s Hard Lessons Might Prepare Business for Climate Change
can deliver the safest perceived service environment, in the face of ongoing public health threats from COVID-19 and from the next pandemic. Sustaining their business viability post-COVID will demand more resources and a higher carbon... View Details
Keywords: by Danielle Kost
- 29 May 2012
- First Look
First Look: May 29
of strong ties to resistors accruing to the change agent are weaker and may yet turn into liabilities that reduce the likelihood of change adoption. Analyses of longitudinal data from 68 multi-method case studies of organizational change initiatives conducted at the... View Details
Keywords: Sean Silverthorne
- 18 Feb 2009
- First Look
First Look: February 18, 2009
School Case 809-009 To help her finance her aggressive expansion plans, Genevieve Thiers plans to raise venture capital for the first time. She has spent the last six long years building Sittercity into the nation's leading babysitting... View Details
Keywords: Martha Lagace
- December 2010
- Teaching Note
Roche's Acquisition of Genentech (TN)
By: Bo Becker and Carliss Y. Baldwin
Teaching Note for 210-040. View Details
- 14 May 2013
- First Look
First Look: May 14
P/E industries, which have a negative valuation change in the year after the investment. 2006 New England Journal of Medicine Leading Clinicians and Clinicians Leading By: Bohmer, Richard M.J. Abstract—More effective models of care... View Details
Keywords: Sean Silverthorne
- 07 Aug 2007
- First Look
First Look: August 7, 2007
providing information for students on CWA's history, the nature of Section 363 auctions, and the bidders who were involved in the process. Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=908004 Connectivity in View Details
Keywords: Martha Lagace
- 10 Oct 2007
- First Look
First Look: First Look: October 10
to customize therapy for individuals. However, adoption of this approach has progressed slowly and unevenly because the trial-and-error treatment model still governs how the health care system develops,... View Details
Keywords: Martha Lagace
- January 2002
- Case
Price-Fixing Vignettes
By: Guhan Subramanian and Michelle Kalka
This case escribes the antitrust prosecutions in the United States and abroad of the international bulk vitamins cartel. Both the civil and criminal fines were historically high, and it was the first time the United States prosecuted foreign nationals for U.S. criminal... View Details
Keywords: Price; Lawsuits and Litigation; Governance Compliance; Auctions; Laws and Statutes; Monopoly; Globalized Markets and Industries; Health Industry; Health Industry; United States
Subramanian, Guhan, and Michelle Kalka. "Price-Fixing Vignettes." Harvard Business School Case 902-068, January 2002.
- March 2021 (Revised May 2021)
- Supplement
Blue Meridian Partners (B): Pivoting in a Crisis
The (B) case situated in 2020 describes the many quick decisions taken by the fund in response to the COVID-19 pandemic and the calls for social justice, and raises the question of whether and how these decisions are aligned with the long range strategy of the fund. View Details
Keywords: Venture Philanthropy; COVID-19; Philanthropy and Charitable Giving; Venture Capital; Social Issues; Health Pandemics; Decisions; Strategy
Rangan, V. Kasturi. "Blue Meridian Partners (B): Pivoting in a Crisis." Harvard Business School Supplement 521-091, March 2021. (Revised May 2021.)
- 15 Sep 2008
- Research & Ideas
The Coming Transformation of Social Enterprise
sense when the for-profit and nonprofit parts are tightly linked by a common purpose or platform. For example, in health care several very successful social entrepreneurs have created a hybrid model where... View Details
Keywords: by Roger Thompson
- January 2021 (Revised June 2021)
- Case
Hester Pharmaceuticals (A): A Pricing Dilemma
By: Dante Roscini and John Masko
In August 2019, the leadership of Hester Pharmaceuticals (Hester) had a problem. Italy promised to be a key market for their new breakthrough oncology drug Akrozumab, but for almost two years, its single-payer healthcare system had been unable to agree with Hester on a... View Details
Keywords: Macroeconomics; Trade; Price; Global Range; Global Strategy; Globalized Markets and Industries; Health Care and Treatment; Patents; Monopoly; Negotiation; Business and Government Relations; Risk and Uncertainty; Human Needs; Business Strategy; Commercialization; Pharmaceutical Industry; Italy
Roscini, Dante, and John Masko. "Hester Pharmaceuticals (A): A Pricing Dilemma." Harvard Business School Case 721-001, January 2021. (Revised June 2021.)