Publications
Publications
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- Faculty Publications (639)
- 2024
- Working Paper
Cephalosporins—Fighting Hospital Infections: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
This case history describes the development of three generations of cephalosporins – antibiotics that have significantly reduced hospital infections. Specifically, we chronicle how: 1) Early (pre-cephalosporin) antibiotics were developed in the first half of the 20th... View Details
- 2024
- Working Paper
Prozac—Controversial Blockbuster: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes the development of Prozac, a blockbuster drug that transformed
the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we
chronicle the: 1) prior treatments for depression and the research that... View Details
- 2024
- Working Paper
Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for
millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s
development; the initial development of tamoxifen from 1960 to 1973;... View Details
- June 2020 (Revised January 2024)
- Case
TraceTogether
By: Mitchell B. Weiss and Sarah Mehta
By April 7, 2020, over 1.4 million people worldwide had contracted the novel coronavirus (COVID-19). Governments raced to curb the spread of COVID-19 by scaling up testing, quarantining those infected, and tracing their possible contacts. It had taken Singapore’s... View Details
Keywords: COVID-19; Contact Tracing; Government Administration; Crisis Management; Health; Health Pandemics; Innovation and Invention; Innovation Leadership; Innovation Strategy; Technological Innovation; Social Issues; Information Technology; Mobile and Wireless Technology; Applications and Software; Technology Adoption; Health Industry; Public Administration Industry; Singapore
- April 2020 (Revised October 2021)
- Case
SpaceX, Economies of Scale, and a Revolution in Space Access
By: Matthew C. Weinzierl, Kylie Lucas and Mehak Sarang
From the time he transformed the world of online banking, Elon Musk established himself as a bold innovator. After selling X.com to PayPal in 2002, he founded a series of revolutionary start-ups, starting with Space Exploration Technologies (SpaceX). Hoping to "make... View Details
- April 2020
- Case
TiVo 2020
By: David B. Yoffie and Daniel Fisher
This short case provides an update on TiVo from 2016-2020. The case covers TiVo merger with Rovi, the turnover of several CEOs, and struggles on how to reposition its product business (the digital video recorder). View Details
- April 2020
- Case
Apple Inc. in 2020
By: David B. Yoffie and Daniel Fisher
After a decade as CEO, Tim Cook is facing one of his biggest strategic transitions of his tenure. While Apple had performed spectacularly well under Cook, Apple's core business was maturing. Sales of iPhones, iPads, and Macs were flat or down. However, Apple's new... View Details
Keywords: Innovation; Market Positioning; Marketing Implementation; Planning; Products; Strategic Positioning; Strategy; Information Technology; Competitive Strategy; Technological Innovation; Competitive Advantage; Product Positioning; Communication; Competition; Leadership; Strategic Planning; Computer Industry; Telecommunications Industry; Technology Industry
- April 2020
- Article
Technological Leadership (de)Concentration: Causes in Information and Communication Technology Equipment
By: Yasin Ozcan and Shane Greenstein
Using patent data from 1976 to 2010 as indicators of inventive activity, we determine the concentration level of where inventive ideas originate and then examine how and why those concentrations change over time. The analysis finds pervasive deconcentration in every... View Details
- March 2020
- Case
SRS and the Defense Innovation Unit: Rethinking Procurement
By: Paul A. Gompers and David Lane
SRS and the Defense Innovation Unit (DIU) follows the process by which SRS, a lean maker of remotely-operated submersible vehicles, navigates the DIU’s acquisition process. Set up in 2015 to speed the U.S. military’s access to promising commercial technologies, the DIU... View Details
- March 2020
- Case
Voi Technology
By: Jeffrey F. Rayport and Olivia Hull
Voi Technology, a fast-growing start-up out of Sweden, is competing in the highly contested European e-scooter sharing market. With a presence in nearly 40 cities in Europe by February 2020, the firm is working hard to improve its unit economics to reach profitability.... View Details
Keywords: Entrepreneurship; Business Strategy; Technology Adoption; Innovation Strategy; Technological Innovation; Marketing Strategy; Business Plan; Product Marketing; Product Launch; Product Positioning; Energy Conservation; Cross-Cultural and Cross-Border Issues; Global Strategy; Globalized Economies and Regions; Innovation Leadership; Human Capital; Laws and Statutes; Growth Management; Operations; Logistics; Service Operations; Supply Chain Management; Organizational Culture; Information Infrastructure; Transportation; Transportation Industry; Technology Industry; Europe
- February 28, 2020
- Article
How Tesla Sets Itself Apart
By: Lou Shipley
Tesla and its flamboyant, and sometimes erratic, innovator Elon Musk have turned the more than a century old industry upside down in a mere 16 years. Traditional automakers are ill prepared to compete in today’s software-centered world. Unlike nimble Tesla, they are... View Details
- 2020
- Working Paper
Design in the Age of Artificial Intelligence
By: Roberto Verganti, Luca Vendraminelli and Marco Iansiti
Artificial Intelligence (AI) is affecting the scenario in which innovation takes place. What are the implications for our understanding of design? Is AI just another digital technology that, akin to many others, will not significantly question what we know about... View Details
- February 2020 (Revised March 2020)
- Case
Prime Coalition: Catalytic Capital for Climate Innovation
By: Ramana Nanda, Benjamin N. Roth and Olivia Hull
With long development timelines and high risk, new energy technologies were often left to languish in the “valley of death,” unable to raise enough funds to bring a product to market. In 2014, Sarah Kearney founded the nonprofit Prime Coalition to solve this problem.... View Details
Keywords: Energy Conservation; Renewable Energy; Social Entrepreneurship; Venture Capital; Investment; Innovation and Invention; Technological Innovation; Mission and Purpose; Science-Based Business; Nonprofit Organizations; Social Enterprise; Energy Industry; Technology Industry; Green Technology Industry; United States
- 2019
- Article
Go-Shops Revisited
By: Guhan Subramanian and Annie Zhao
A go-shop process turns the traditional M&A deal process on its head: rather than a pre-signing market canvass followed by a post-signing “no shop” period, a go-shop deal involves a limited pre-signing market check, followed by a post-signing “go shop” process to find... View Details
- January–February 2020
- Article
Competing in the Age of AI
By: Marco Iansiti and Karim R. Lakhani
Today’s markets are being reshaped by a new kind of firm—one in which artificial intelligence (AI) runs the show. This cohort includes giants like Google, Facebook, and Alibaba, and growing businesses such as Wayfair and Ocado. Every time we use their services, the... View Details
- January 2020
- Case
The Origins of Bell Labs
By: Tom Nicholas and John Masko
In 1947, scientists at Bell Labs invented the transistor—a tiny signal amplifier that would go on to become the fundamental building block of the digital age. But, confounding most traditional economic assumptions, it was not a vigorous startup that made this momentous... View Details
- 2020
- Book
Competing in the Age of AI: Strategy and Leadership When Algorithms and Networks Run the World
By: Marco Iansiti and Karim R. Lakhani
In industry after industry, data, analytics, and AI-driven processes are transforming the nature of work. While we often still treat AI as the domain of a specific skill, business function, or sector, we have entered a new era in which AI is challenging the very... View Details
- December 2019
- Case
Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem (Abridged)
By: Willy Shih
This case describes the efforts of the Bill & Melinda Gates Foundation to lower the cost of producing vaccines to prevent polio infections. It is an abridged version of HBS Case No. 620-021 with less emphasis on comparison between traditional and the new compact... View Details
- December 2019
- Case
Forecasting ClimaCell
By: Joshua Lev Krieger, Christopher Stanton and James Barnett
A weather technology startup, ClimaCell considers the R&D trade-offs and financing implications of pursuing a proposed contract with a major automobile maker, rather than continuing its focus on building a scalable, all-purpose weather prediction engine. View Details
- 2019
- Article
Overcoming Cultural Resistance to Open Source Innovation
By: John Winsor, Jin Hyun Paik, Michael Tushman and Karim R. Lakhani
Purpose: This article offers insight on how to effectively help incumbent organizations prepare for global business shifts to open source and digital business models.
Design/methodology/approach: Discussion related to observation, experience and case studies... View Details
Design/methodology/approach: Discussion related to observation, experience and case studies... View Details