Publications
Publications
Show Results For
- All HBS Web
(5,945)
- Faculty Publications (1,519)
science
→
- June 2023
- Case
Verve Therapeutics: Taking DNA Editing to Heart
By: Shikhar Ghosh and Shweta Bagai
Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
- June, 2023
- Article
Walking the Purpose-Talk Inside a Large Company: Sustainable Product Development as an Instance of Divergent Change
By: Marissa Kimsey, Thijs Geradts and Julie Battilana
There is a growing interest in large companies pursuing a new purpose—changing their core reason for being from a singular focus on financial gain to a renewed responsibility to people and the planet alongside profit. Yet knowledge of how a large company can walk that... View Details
- 2023
- Article
Exploiting Discovered Regression Discontinuities to Debias Conditioned-on-observable Estimators
By: Benjamin Jakubowski, Siram Somanchi, Edward McFowland III and Daniel B. Neill
Regression discontinuity (RD) designs are widely used to estimate causal effects in the absence of a randomized experiment. However, standard approaches to RD analysis face two significant limitations. First, they require a priori knowledge of discontinuities in... View Details
- May 2023 (Revised November 2023)
- Case
Arcos Dorados: Decarbonizing McDonald's in Latin America
By: George Serafeim, Michael W. Toffel, Jenyfeer Martinez Buitrago and Mariana Cal
This case describes the decarbonization strategy of Arcos Dorados—McDonald’s largest independent franchisee, operating in 20 countries and territories in Latin America and the Caribbean—and how the company measured its greenhouse gas (GHG) emissions, including those... View Details
Keywords: Environmental Accounting; Animal-Based Agribusiness; Plant-Based Agribusiness; Change Management; Forecasting and Prediction; Environmental Sustainability; Food; Growth Management; Supply Chain; Corporate Social Responsibility and Impact; Strategy; Agriculture and Agribusiness Industry; Food and Beverage Industry; Green Technology Industry; Consumer Products Industry; Latin America; North and Central America; South America
- May 2023 (Revised June 2023)
- Case
Harvard University and Urban Mining Industries: Decarbonizing the Supply Chain
By: Shirley Lu and Robert S. Kaplan
The case describes Harvard University’s consideration to decarbonize its supply chain by replacing cement with a low-carbon substitute called Pozzotive®. Developed and produced by Urban Mining Industries, Pozzotive® is a ground-glass material made with post-consumer... View Details
- April 2023
- Technical Note
An Art & A Science: How to Apply Design Thinking to Data Science Challenges
By: Michael Parzen, Eddie Lin, Douglas Ng and Jessie Li
We hear it all the time as managers: “what is the data that backs up your decisions?” Even local mom-and-pop shops now have access to complex point-of-sale systems that can closely track sales and customer data. Social media influencers have turned into seven-figure... View Details
- April 2023
- Case
Fizzy Fusion: When Data-Driven Decision Making Failed
By: Michael Parzen, Eddie Lin, Douglas Ng and Jessie Li
This is a case about a fictional New York beverage company called Fizzy Fusion. The business is facing supply chain and inventory management challenges with its new product, SparklingSip. Despite seeking help from a data science consulting firm, the machine learning... View Details
- April 5, 2023
- Article
We Need an Operation Warp Speed for Long COVID
By: Esther K. Choo and Scott Duke Kominers
With millions of people affected and at least $1 trillion of economic value at stake, long COVID is our next national health emergency. View Details
- April 3, 2023
- Article
Getting a Clearer View of Your Company’s Carbon Footprint
By: Robert S. Kaplan, Karthik Ramanna and Stefan Reichelstein
E-liability accounting is a new technique that will help customers factor in a product’s environmental footprint into their purchasing decisions and will help create a competition dynamic that leads to reduced carbon outputs. This article describes two pilot studies—by... View Details
- 2023
- Working Paper
Corporate Website-based Measures of Firms' Value Drivers
By: Wei Cai, Dennis Campbell and Patrick Ferguson
We develop and validate new text-based measures of firms’ financial and non-financial value drivers. Using the Wayback Machine to access public US firms’ archived websites from 1995-2020, we scrape text from corporate homepages. We use Kaplan and Norton’s (1992)... View Details
- 2023
- Working Paper
Feature Importance Disparities for Data Bias Investigations
By: Peter W. Chang, Leor Fishman and Seth Neel
It is widely held that one cause of downstream bias in classifiers is bias present in the training data. Rectifying such biases may involve context-dependent interventions such as training separate models on subgroups, removing features with bias in the collection... View Details
- 2023
- Working Paper
PRIMO: Private Regression in Multiple Outcomes
By: Seth Neel
We introduce a new differentially private regression setting we call Private Regression in Multiple Outcomes (PRIMO), inspired the common situation where a data analyst wants to perform a set of l regressions while preserving privacy, where the covariates... View Details
- April 2023
- Article
The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’
In their Discussion Paper, Franzoni and Stephan (F&S, 2023) discuss the shortcomings of existing peer review models in shaping the funding of risky science. Their discussion offers a conceptual framework for incorporating risk into peer review models of research... View Details
- March 2023
- Supplement
Allianz Türkiye (B): Adapting to a Changing World
By: John D. Macomber and Fares Khrais
- March 2023
- Supplement
Allianz Türkiye (C): Managing the 2017 Hail Storm
By: John D. Macomber and Fares Khrais
Allianz Turkey is a property casualty insurance company operating in a region experiencing increasing losses from natural catastrophe events related to climate change, for example hail, wildfire, and flooding. There are also substantial other natural catastrophe... View Details
- March 2023 (Revised April 2024)
- Case
Allianz Türkiye: Adapting to Climate Change
By: John D. Macomber and Fares Khrais
Allianz Turkey is a property casualty insurance company operating in a region experiencing increasing losses from natural catastrophe events related to climate change, for example hail, wildfire, and flooding. There are also substantial other natural catastrophe... View Details
- March 2023 (Revised June 2023)
- Case
Metaverse Wars
By: Andy Wu, David B. Yoffie and Matt Higgins
In 2023, the term metaverse — a combination of “meta” and “universe” — had become a catch-all for a diverse set of expectations about online virtual worlds and the future of the internet. To some, the metaverse conjured images of a massive participatory videogame... View Details
- March 2023
- Case
Azenta Life Sciences: The Road to Transformation
By: Gary P. Pisano and Catherine Piner
When the Board brought Steve Schwartz in as President of Brooks Automation in 2010, they gave him a clear mission: strengthen the company’s core semiconductor equipment business and find a new industry to enter. Over the course of the next decade, Schwartz and the... View Details
- March 2023
- Teaching Note
Sustainability Reporting at Dollar Tree, Inc.
By: Suraj Srinivasan and Li-Kuan Ni
Teaching Note for HBS Case No. 122-044. The case discusses the ESG strategy of Dollar Tree Inc., a U.S. Fortune 500 company in the deep discount retail industry and the shareholder pressure faced by the company. In 2022, the company faced a shareholder resolution from... View Details
Keywords: ESG; Sustainability; Shareholder Activism; Dollar Tree; Sustainability Reporting; ESG Reporting; Board Of Directors; Shareholder Engagement; GHG; Environmental Accounting; Integrated Corporate Reporting; Trends; Communication; Announcements; Voting; Environmental Management; Climate Change; Environmental Sustainability; Values and Beliefs; Corporate Accountability; Corporate Disclosure; Corporate Governance; Governing Rules, Regulations, and Reforms; Policy; Reports; Business or Company Management; Risk Management; Corporate Social Responsibility and Impact; Outcome or Result; Strategic Planning; Business and Stakeholder Relations; Situation or Environment; Opportunities; Civil Society or Community; Social Issues; Public Opinion; Strategy; Adaptation; Alignment; Business Strategy; Corporate Strategy; Value Creation; Retail Industry; United States; Virginia
- March 2023 (Revised May 2025)
- Case
On (A)
By: Ramon Casadesus-Masanell, Karolin Frankenberger and Sascha Mader
Founded in 2010, in just one decade, the Swiss company On had established itself as a main player in global sports footwear and apparel. Based on an unconventional strategy which one of the founders labeled as “obsessively distinct,” On grew its sales with a compound... View Details
Keywords: Brands and Branding; Business Growth and Maturation; Business Model; Business Startups; Business Strategy; Competitive Advantage; Competitive Strategy; Corporate Strategy; Customer Focus and Relationships; Customer Satisfaction; Digital Marketing; Disruptive Innovation; Distribution Channels; Entrepreneurship; Environmental Sustainability; Global Strategy; Initial Public Offering; Innovation and Invention; Innovation Strategy; Market Entry and Exit; Marketing Strategy; Product Design; Product Development; Product Marketing; Social Media; Strategy; Supply Chain Management; Technological Innovation; Apparel and Accessories Industry; Consumer Products Industry; Manufacturing Industry; Retail Industry; Sports Industry; Europe; Switzerland; Germany; United States