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      • November 2022
      • Case

      Ajax Health: A New Model for Medical Technology Innovation

      By: Regina E. Herzlinger and Ben Creo
      This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
      Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Technology Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
      • November 2022
      • Background Note

      The Future of E-Commerce: Lessons from the Livestream Wars in China

      By: Ayelet Israeli, Jeremy Yang and Billy Chan
      This note explores the emerging multi-billion dollar commerce trend of livestream commerce. Livestream commerce is the sale of goods or services directly to consumers via live shows on digital platforms (such as social media or e-commerce platforms). It is a form of... View Details
      Keywords: Retail; Retailing; E-commerce; E-Commerce Strategy; Ecommerce; Channels Of Distribution; Marketing Communication; Livestream Commerce; Marketing; Marketing Channels; Marketing Strategy; Advertising; Brands and Branding; Media; Consumer Behavior; Social Media; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; China; United States; United Kingdom
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      Israeli, Ayelet, Jeremy Yang, and Billy Chan. "The Future of E-Commerce: Lessons from the Livestream Wars in China." Harvard Business School Background Note 523-055, November 2022.
      • November 2022 (Revised December 2024)
      • Case

      Hugging Face (A): Serving AI on a Platform

      By: Shane Greenstein, Daniel Yue, Sarah Gulick and Kerry Herman
      It is fall 2022, and open-source AI model company Hugging Face is considering its three areas of priorities: platform development, supporting the open-source community, and pursuing cutting-edge scientific research. As it expands services for enterprise clients, which... View Details
      Keywords: Community; Open-source; AI and Machine Learning; Product Development; Networks; Service Delivery; Research; Governance; Business and Stakeholder Relations; Information Industry; Technology Industry; United States
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      Greenstein, Shane, Daniel Yue, Sarah Gulick, and Kerry Herman. "Hugging Face (A): Serving AI on a Platform." Harvard Business School Case 623-026, November 2022. (Revised December 2024.)
      • October 2022
      • Case

      Pricing at Echosec Systems

      By: Elie Ofek, Marco Bertini, Annelena Lobb and Alexis Lefort
      This case follows the evolution of pricing strategy at Echosec Systems, a Canadian open source intelligence firm. The case provides information on pricing as the company grows and diversifies its product offerings. View Details
      Keywords: Marketing Strategy; Product Positioning; Price; Product Development; Information Industry; Canada; United States
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      Ofek, Elie, Marco Bertini, Annelena Lobb, and Alexis Lefort. "Pricing at Echosec Systems." Harvard Business School Case 523-052, October 2022.
      • October 2022 (Revised June 2025)
      • Case

      Lyra Health: Transforming Mental Health

      By: Rembrand Koning and Nicole Keller
      In January 2022, Lyra Health was deciding between several different alternatives to grow the business. Founded in 2015, Lyra Health was a digital mental health platform that combined technology with human therapists and coaches to deliver high quality mental health... View Details
      Keywords: Mental Health; Health Care and Treatment; Corporate Entrepreneurship; Customer Value and Value Chain; Growth and Development Strategy; Expansion; Health Industry; Technology Industry; San Francisco
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      Koning, Rembrand, and Nicole Keller. "Lyra Health: Transforming Mental Health." Harvard Business School Case 723-365, October 2022. (Revised June 2025.)
      • October 2022
      • Case

      Afrigen Biologics: Vaccines for the Global South

      By: Debora L. Spar and Julia Comeau
      The majority of vaccines used on the continent of Africa (99%) are produced offshore. This makes African nations reliant on the West for major health care needs, a problem which was exacerbated by the COVID-19 pandemic. Afrigen Biologics (in partnership with the WHO)... View Details
      Keywords: Vaccination; Vaccine; mRNA; COVID; COVID-19; Inequity; Hub-and-spoke; Health Care and Treatment; Health Pandemics; Production; Social Issues; Business and Government Relations; South Africa; Africa
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      Spar, Debora L., and Julia Comeau. "Afrigen Biologics: Vaccines for the Global South." Harvard Business School Case 323-030, October 2022.
      • October 2022 (Revised September 2024)
      • Case

      mPharma: Scaling Access to Affordable Primary Care in Africa

      By: Regina E. Herzlinger and Ben Creo
      mPharma hopes to scale up to create the largest pan-African healthcare company ever to provide much-needed primary care in retail pharmacies; a reliable, fairly priced supply of drugs; and micro-insurance for drugs. They must prioritize launching a telemedicine... View Details
      Keywords: Africa; Pharmaceutical Companies; Pharmacy Benefit Manager; Health Care; Health Care And Treatment; Health Care Costs; Health Care Delivery; Health Care Entrepreneurship; Telehealth; Health Equity; Corporate Strategy; Social Entrepreneurship; Equity; Growth and Development Strategy; Expansion; Product Launch; Customer Value and Value Chain; Social Enterprise; Multinational Firms and Management; Pharmaceutical Industry; Health Industry; Africa
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      Herzlinger, Regina E., and Ben Creo. "mPharma: Scaling Access to Affordable Primary Care in Africa." Harvard Business School Case 323-033, October 2022. (Revised September 2024.)
      • October 2022
      • Case

      Beam Dental (A)

      By: Rembrand Koning and Alicia Dadlani
      In May 2014, Alex Frommeyer, cofounder and CEO of Kentucky-based Beam Dental, a seed-stage startup that developed connected toothbrushes that tracked brushing habits, needed to decide which strategy to pitch to a venture capital firm. The first pitch deck played to the... View Details
      Keywords: Business Startups; Business Strategy; Entrepreneurship; Financing and Loans; Presentations; Product Development; Insurance Industry; United States; Kentucky; Ohio
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      Koning, Rembrand, and Alicia Dadlani. "Beam Dental (A)." Harvard Business School Case 723-355, October 2022.
      • October 2022 (Revised September 2024)
      • Case

      Podimetrics: Next Steps for Diabetes Cases

      By: Regina E. Herzlinger and Ben Creo
      Podimetrics, a virtual care management company treating adults with acute diabetes, sat at the intersection of medical device technology, digital health, and health services. Its SmartMat had demonstrated that it could help prevent amputations and that people with... View Details
      Keywords: Health Care; Health Care Delivery; Health Care Entrepreneurship; Health Care Outcomes; Diabetes; Chronic Disease; Chronic Illness; Health Care and Treatment; Health Disorders; Medical Specialties; Technological Innovation; Innovation Strategy; Product Development; Business Model; Customer Focus and Relationships; Medical Devices and Supplies Industry; Health Industry
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      Herzlinger, Regina E., and Ben Creo. "Podimetrics: Next Steps for Diabetes Cases." Harvard Business School Case 323-015, October 2022. (Revised September 2024.)
      • September 2022 (Revised November 2023)
      • Case

      Wordle

      By: Karen G. Mills, Christina Wallace, Ebehi Iyoha, Gabriella Elanbeck and Morgane Herculano
      After sourdough bread, countertop chive gardens, and vaccine selfies came a pandemic-era trend that everyone seemed to be in on: one daily chance to guess a five-letter word and crow about your success on social media via little green and yellow squares. From a... View Details
      Keywords: Games; Innovation; General Management; Mergers and Acquisitions; Trends; Entrepreneurship; Bids and Bidding; Consumer Behavior; Entertainment and Recreation Industry; Technology Industry
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      Mills, Karen G., Christina Wallace, Ebehi Iyoha, Gabriella Elanbeck, and Morgane Herculano. "Wordle." Harvard Business School Case 323-032, September 2022. (Revised November 2023.)
      • September 2022
      • Article

      Find and Replace: R&D Investment Following the Erosion of Existing Products

      By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor
      How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first... View Details
      Keywords: R&D Investments; Drug Development; Product Shocks; M&A; Biopharmaceutical Industry; FDA; System Shocks; Research and Development; Investment; Decision Making; Pharmaceutical Industry
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      Krieger, Joshua L., Xuelin Li, and Richard T. Thakor. "Find and Replace: R&D Investment Following the Erosion of Existing Products." Management Science 68, no. 9 (September 2022): 6552–6571.
      • August 2022 (Revised March 2025)
      • Case

      Wasabi Technologies (A)

      By: N. Louis Shipley and Mel Martin
      After launching a successful hot cloud storage company, Founder and CEO David Friend is ready to scale the venture rapidly. Wasabi Technologies had focused primarily on direct sales, but an opportunity to pivot to channel sales was on the horizon. The company’s major... View Details
      Keywords: Direct Sales; Channel Sales; Information Management; Sales; Product Development; Growth and Development Strategy; Business Divisions; Information Technology Industry; United States
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      Shipley, N. Louis, and Mel Martin. "Wasabi Technologies (A)." Harvard Business School Case 823-021, August 2022. (Revised March 2025.)
      • August 2022
      • Case

      Meaningful Gigs

      By: Brian Trelstad and Rachel Philbin
      In October 2020, just a year after founding their company Meaningful Gigs, founders Ronnie Kwesi Coleman and Stephanie Nachemja-Burton prepared for a vital investment meeting with Rethink Education. They had already reached $400,000 in annually recurring revenue (ARR)... View Details
      Keywords: Venture Capital; Growth and Development Strategy; Revenue; Education Industry; Technology Industry; Africa; United States
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      Trelstad, Brian, and Rachel Philbin. "Meaningful Gigs." Harvard Business School Case 323-006, August 2022.
      • August 2022
      • Case

      One Tiger Per Mountain: The He Family Office

      By: Lauren Cohen, Fei Wu and Grace Headinger
      Roy He, founder and majority shareholder of his family construction material production company, was preparing to pass down the family business through its first generational handover to his children. His decision would establish his familial legacy and set a precedent... View Details
      Keywords: Governance Structure; Family Business; Family Ownership; Strategic Planning; Family and Family Relationships; Leadership; Construction Industry; Canton (city, China); Canton (province, China); China
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      Cohen, Lauren, Fei Wu, and Grace Headinger. "One Tiger Per Mountain: The He Family Office." Harvard Business School Case 223-001, August 2022.
      • 2024
      • Working Paper

      The Impact of the Chinese Exclusion Act on the Economic Development of the Western U.S.

      By: Joe Long, Carlo Medici, Nancy Qian and Marco Tabellini
      This paper investigates the economic consequences of the 1882 Chinese Exclusion Act, which banned immigration from China. The Act reduced the number of Chinese workers of all skill levels living in the United States. It also reduced the labor supply and the quality of... View Details
      Keywords: Growth; Productivity; Economic Development; Business History; Economic Slowdown and Stagnation; Business and Government Relations; Prejudice and Bias; Government Legislation; Immigration; United States
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      Long, Joe, Carlo Medici, Nancy Qian, and Marco Tabellini. "The Impact of the Chinese Exclusion Act on the Economic Development of the Western U.S." Harvard Business School Working Paper, No. 23-008, August 2022. (Revised September 2024. Featured in Bloomberg, at Hoover Institute, VoxEU, NBER Digest, NPR, Forbes, The New Yorker, HBS Working Knowledge, Cato Institute, and America: A History (podcast), quoted here.)
      • July 2022
      • Case

      boAt Lifestyle

      By: Rajiv Lal and Kairavi Dey
      boAt began as a lifestyle brand in the consumer electronics category in 2016 with the aim of bringing affordable, durable, and fashionable audio products and accessories to millennials and Gen-Z customers in India. Born in 2016 with Amazon India as its only sales... View Details
      Keywords: Marketing; Brands and Branding; Initial Public Offering; Digital Marketing; Product Development; Product Marketing; Business or Company Management; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Asia; India
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      Lal, Rajiv, and Kairavi Dey. "boAt Lifestyle." Harvard Business School Case 523-019, July 2022.
      • July 2022 (Revised August 2022)
      • Case

      Athletic Brewing Company: Crafting the U.S. Non-Alcoholic Beer Category

      By: Ayelet Israeli and Anne V. Wilson
      Athletic Brewing Company (“Athletic,” for short) was founded by Bill Shufelt and John Walker in 2017. In creating Athletic, Shufelt and Walker opened the first U.S. brewery and taproom fully devoted to the production of non-alcoholic (NA) craft beer. By 2021, Athletic... View Details
      Keywords: Advertising; Brands and Branding; Product Development; Product Marketing; Product Positioning; Product Launch; Product Design; Product; Competition; Marketing; Entrepreneurship; Growth Management; Cultural Entrepreneurship; Culture; Food and Beverage Industry; United States
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      Israeli, Ayelet, and Anne V. Wilson. "Athletic Brewing Company: Crafting the U.S. Non-Alcoholic Beer Category." Harvard Business School Case 523-021, July 2022. (Revised August 2022.)
      • July 2022 (Revised February 2024)
      • Teaching Note

      The DivaCup: Navigating Distribution and Growth

      By: Ayelet Israeli
      Teaching Note for HBS Case No. 519-055. When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique... View Details
      Keywords: Female; Female Ceo; Female Entrepreneur; Female Protagonist; Health & Wellness; Healthcare; Price Policies; Minimum Advertised Price; Differentiation; Positioning; Growth; Health; Health Care and Treatment; Price; Disruption; Distribution; Distribution Channels; Competitive Strategy; Competition; Growth Management; Mission and Purpose; Product Development; Product Marketing; Product Launch; Product Positioning; Advertising; Business Startups; Internet and the Web; Entrepreneurship; Social Entrepreneurship; Social Issues; Social Enterprise; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Canada; United States; United Kingdom
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      Israeli, Ayelet. "The DivaCup: Navigating Distribution and Growth." Harvard Business School Teaching Note 523-008, July 2022. (Revised February 2024.)
      • July 2022
      • Teaching Note

      Arçelik (A), (B): From a Dealer Network to an Omnichannel Experience

      By: Ayelet Israeli, Fares Khrais and Menna Hassan
      Arçelik Turkey, the country’s market leader in household appliances, was at an omnichannel crossroads in January 2020. Arçelik was a B2B player utilizing a dealership network with an umbrella of brands and had one of the largest brick-and-mortar store networks in... View Details
      Keywords: Digital Marketing; Bricks And Mortar; Franchise Management; Franchising; Dealer Network; Dealers; B2B; B2B2C; Tradition; Culture Change; Cultural Adaptation; Omnichannel; Omnichannel Retail; Omni-channel; Omnichannel Retailing; Sales Channels; Sales Channel Development; Channel Management; Channels Of Distribution; Marketplace; Platforms; Collaboration; Online Channel; Online Data; Online Sales; Online Shopping; Online; Retail; Retailing; Disruption; Transformation; Franchise Ownership; Change Management; Partners and Partnerships; Consumer Behavior; Sales; Internet and the Web; Marketing Strategy; Conflict and Resolution; Conflict Management; Organizational Culture; Distribution Channels; Digital Transformation; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Turkey
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      Israeli, Ayelet, Fares Khrais, and Menna Hassan. "Arçelik (A), (B): From a Dealer Network to an Omnichannel Experience." Harvard Business School Teaching Note 523-009, July 2022.
      • July 2022 (Revised January 2023)
      • Case

      Vicky Tsai and Tatcha: Confronting Stereotypes

      By: Geoffrey Jones and Veronica Tong
      Teaching Plan for HBS Case No. 323-007. This case examines the career of Vicky Tsai, the creator of San Francisco-based TATCHA, a Japanese-themed luxury beauty brand launched in 2009. It explores how Tsai developed the concept, assembled management, and successfully... View Details
      Keywords: Cosmetics Industry; Japan; Startup; Marketing; Entrepreneurship; Growth and Development; Product Development; Product Marketing; Acquisition; Identity; Brands and Branding; Ethnicity; Gender; Beauty and Cosmetics Industry; United States
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      Jones, Geoffrey, and Veronica Tong. "Vicky Tsai and Tatcha: Confronting Stereotypes." Harvard Business School Case 323-007, July 2022. (Revised January 2023.)
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