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- 15 Sep 2009
- First Look
First Look: September 15
http://www.nber.org/papers/w11503 Synthesis by Microbes or Chemists? Pharmaceutical Research and Manufacturing in the Antibiotic Era Author:Arthur A. Daemmrich Publication:History and Technology 23, no. 3... View Details
Keywords: Martha Lagace
- 19 Aug 2002
- Research & Ideas
Here Comes Internet2—Time to Shed Dot Vertigo
The same DVD would take approximately twenty-five hours to download via a standard DSL/cable line (and 170 hours—or more than seven days—via a 56K modem). Genomics and pharmaceuticals are other research... View Details
Keywords: by Martha Lagace
- 13 Jan 2003
- Research & Ideas
Making Biotech Work as a Business
technologies for drug discovery.) And patients with previously unmet medical needs can now get treatments that were not available before. That should be inspiring, he reminded the audience. Economic frustrations remain, however. Pisano cautioned that current data on... View Details
- 07 Aug 2000
- Research & Ideas
The Business of Biotech
coming of age of biotechnology. The disappearance of "blockbuster" drugs could create new management challenges for pharmaceutical companies. — Gary Pisano The prospect is exhilarating, but the road to this brave new biotech... View Details
- 18 Jul 2018
- Research & Ideas
No More General Tso's? A Threat to 'Knowledge Recombination'
Turmeric is prepared into medicine. Doucefleur In the early 1990s, an Indian plastic surgeon at the University of Mississippi, S. K. Das, was about to amputate the leg of a patient because of a wound that wouldn’t heal. Colleague Hari P. Cohly stopped him. A View Details
- 03 Aug 2016
- What Do You Think?
How Can We Hold the “Leadership Industry” Accountable?
these leadership industry issues varied. Pradip commented: “In a competitive industry there are many who want everyone to ‘buy in’ (to) their half baked research as ‘new truth.’” He called for a “rigorous View Details
- Research Summary
Overview
By: Andy Wu
How can technology entrepreneurs build competitive advantage from the ground up? Professor Andy Wu conducts scholarly research and develops course materials that document how technology entrepreneurs can (1) organize for innovation to create new market opportunities... View Details
Keywords: Strategy; Entrepreneurship; Venture Capital; Growth Management; Organizational Design; Organizational Structure; Technology Platform; Technological Innovation; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; United States; China; Southeast Asia; South Asia
- 12 Mar 2014
- Research & Ideas
Entrepreneurship and Multinationals Drive Globalization
volumes, and in the spirit of the whole being greater than the sum of the parts, I sought to pull together my research and conclusions in this book, in the hope of reaching broader audiences. I address three key themes. First, I show that... View Details
- 21 Nov 2006
- First Look
First Look: November 21, 2006
Kathryn S. Roloff Abstract The emergence of a research literature on team learning has been driven by at least two factors. First, longstanding interest in what makes organizational work teams effective leads naturally to questions of how... View Details
Keywords: Sean Silverthorne
- 15 Jan 2018
- Research & Ideas
A Better Business Model for Fighting Cancer
iPhoto With billions of dollars spent on the development of precision medicine and related cancer research over the last decade, a recent partnership seeks a new way to bring these treatments to patients more quickly: through a better... View Details
- 28 Aug 2017
- Research & Ideas
Should Industry Competitors Cooperate More to Solve World Problems?
are persistent issues that in many cases have worsened. "Addressing these issues is critical for the future competitiveness of these industries" In our competitive landscape, ESG efforts are guided by economic incentives. Indeed, my View Details
- 25 Apr 2005
- Research & Ideas
New Learning at American Home Products
pharmaceutical companies in 1984, American Home Products ranked first in sales and twenty-eighth in R&D expenditures as a percentage of sales.23 As the historian Williams Haynes noted, by the end of the 1930s, American Home Products... View Details
- 30 Jun 2003
- Research & Ideas
Computer Security is For Managers, Too
each warrants. A bank, for instance, might assign the greatest amount of protection to the database that stores its customers' financial information. For a pharmaceutical company, it might be the research... View Details
- 12 Oct 2006
- First Look
First Look: October 12, 2006
responsible" investments as well as some consumers, activists, and potential employees. Unfortunately, there is little evidence about the validity of these ratings. We examine how well two of the most widely used ratings—those of Kinder, Lydenberg, Domini View Details
Keywords: Sean Silverthorne
- 10 Sep 2008
- Research & Ideas
Long-Tail Economics? Give Me Blockbusters!
by focusing on bigger films that require a bigger commitment." Jeff Robinov believes in blockbusters and his strategy is to create more of them. The pharmaceutical and entertainment industries are similar. R&D costs in both are... View Details
- 09 Feb 2018
- Working Paper Summaries
Developing Novel Drugs
- 1999
- Chapter
The Economics of Drug Discovery
By: Rebecca M. Henderson and Iain Cockburn
Henderson, Rebecca M., and Iain Cockburn. "The Economics of Drug Discovery." Chap. 5 in Pharmaceutical Innovation, edited by Ralph Landau, Basil Achilladelis, and Alexander Scriabine, 308–331. Philadelphia: Chemical Heritage Press, 1999.
- 18 Aug 2011
- Lessons from the Classroom
Business Plan Contest: 15 Years of Building Better Entrepreneurs
asking, is this the right business model? But there are no answers. The market and technology are constantly changing," Riesenfeld remarks. Important Sounding Board The biotech industry presents similar challenges in a space littered with failed companies. When... View Details
- 2023
- Working Paper
Evaluation and Learning in R&D Investment
By: Alexander P. Frankel, Joshua L. Krieger, Danielle Li and Dimitris Papanikolaou
We examine the role of spillover learning in shaping the value of exploratory versus incremental
R&D. Using data from drug development, we show that novel drug candidates generate more
knowledge spillovers than incremental ones. Despite being less likely to reach... View Details
Frankel, Alexander P., Joshua L. Krieger, Danielle Li, and Dimitris Papanikolaou. "Evaluation and Learning in R&D Investment." Harvard Business School Working Paper, No. 23-074, May 2023. (NBER Working Paper Series, No. 31290, May 2023.)
- 26 Apr 2011
- Op-Ed
HBS Faculty Comment on Environmental Issues for Earth Day
always, more than half the challenge is creating and implementing the new management processes that make smart technologies work. In short, the so-called "soft stuff" presents challenges that will occupy management researchers and... View Details