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  • February 2015 (Revised November 2015)
  • Case

Building an Integrated Biopharma Company: Crucell (A)

By: Richard G. Hamermesh, Marianne Van Der Steen and Susan S. Harmeling
By 2009, Crucell had become the largest biopharma company in the Netherlands and a symbol of national pride. The case traces the evolution of the company from a University spin-off into a fully-integrated company. Crucell's success, particularly in the vaccine space,... View Details
Keywords: Biotechnology; Biopharmacy Company; Licensing; Licensing Agreements In Biopharmacy; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Partners and Partnerships; Entrepreneurship; Growth and Development Strategy; Biotechnology Industry; Pharmaceutical Industry; Netherlands
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Hamermesh, Richard G., Marianne Van Der Steen, and Susan S. Harmeling. "Building an Integrated Biopharma Company: Crucell (A)." Harvard Business School Case 815-085, February 2015. (Revised November 2015.)
  • October 2022 (Revised August 2024)
  • Case

Cigna-Express Scripts: Can a Vertical Merger Rescue an Industry Under Attack?

By: Leemore Dafny
In Fall 2019, Cigna Corporation – a global health services company with a significant presence in the U.S. employer-sponsored health insurance market - was digesting its $54 billion acquisition of Express Scripts, Inc. (ESI), a pharmacy benefit manager (PBM)... View Details
Keywords: Mergers and Acquisitions; Business Model; Vertical Integration; Insurance Industry
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Dafny, Leemore. "Cigna-Express Scripts: Can a Vertical Merger Rescue an Industry Under Attack?" Harvard Business School Case 323-038, October 2022. (Revised August 2024.)
  • December 12, 2023
  • Article

Prices for Common Services at Quaternary vs Nonquaternary Hospitals

By: Brandon W. Yan, Maximilian J. Pany and Leemore S. Dafny
Using commercial health insurance claims data from 2017-2019, we assessed whether quaternary hospitals charged higher prices for common, unspecialized services also offered by nonquaternary hospitals. We found quaternary-hospital price premiums of 8.2 percent, on... View Details
Keywords: Price; Health Care and Treatment; Insurance; Markets; Health Industry
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Yan, Brandon W., Maximilian J. Pany, and Leemore S. Dafny. "Prices for Common Services at Quaternary vs Nonquaternary Hospitals." JAMA, the Journal of the American Medical Association 330, no. 22 (December 12, 2023): 2211–2213.
  • November 2002
  • Compilation

Four Principles of Biomedical Ethics: Definitions and Examples

By: Sandra J. Sucher
Introduces four principles of biomedical ethics, excerpted from Principles of Biomedical Ethics, Tom L. Beauchamp and James F. Childress (Oxford University Press, 2001). The principles provide a conceptual framework for the analysis and resolution of moral problems... View Details
Keywords: Framework; Moral Sensibility; Health Care and Treatment; Distribution; Problems and Challenges; Research; Emotions; Management Analysis, Tools, and Techniques; Health Industry; Health Industry
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Sucher, Sandra J. "Four Principles of Biomedical Ethics: Definitions and Examples." Harvard Business School Compilation 603-079, November 2002.
  • 2019
  • Chapter

Behavioral Economics and Health-Care Markets

By: Amitabh Chandra, Benjamin Handel and Joshua Schwartzstein
This chapter summarizes research in behavioral health economics, focusing on insurance markets and product markets in health care. We argue that the prevalence of choice difficulties and biases leading to mistakes in these markets establish a special place for them in... View Details
Keywords: Behavioral Economics; Consumer Behavior; Economics; Health Care and Treatment; Insurance; Markets
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Chandra, Amitabh, Benjamin Handel, and Joshua Schwartzstein. "Behavioral Economics and Health-Care Markets." Chap. 6 in Handbook of Behavioral Economics: Foundations and Applications 2, edited by B. Douglas Bernheim, Stefano DellaVigna, and David Laibson, 459–502. Amsterdam: Elsevier/North-Holland, 2019.
  • Article

The Economic Consequences of Hospital Admissions

By: Carlos Dobkin, Amy Finkelstein, Raymond Kluender and Matthew Notowidigdo
We use an event study approach to examine the economic consequences of hospital admissions for adults in two datasets: survey data from the Health and Retirement Study, and hospitalization data linked to credit reports. For non-elderly adults with health insurance,... View Details
Keywords: Personal Finance; Borrowing and Debt; Insurance; Insolvency and Bankruptcy; Health Care and Treatment
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Dobkin, Carlos, Amy Finkelstein, Raymond Kluender, and Matthew Notowidigdo. "The Economic Consequences of Hospital Admissions." American Economic Review 108, no. 2 (February 2018): 308–352.
  • May 2007 (Revised July 2011)
  • Case

The West German Headache Center: Integrated Migraine Care

By: Michael E. Porter, Clemens Guth and Elisa M. Dannemiller
Describes the joint efforts of the German health plan KKH and Essen University Hospital to develop an integrated practice unit (IPU), and the West German Headache Center's efforts to improve the quality of migraine care. Provides an overview of the German health care... View Details
Keywords: Business Model; Health Care and Treatment; Medical Specialties; Industry Structures; Service Delivery; Integration; Health Industry; Germany
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Porter, Michael E., Clemens Guth, and Elisa M. Dannemiller. "The West German Headache Center: Integrated Migraine Care." Harvard Business School Case 707-559, May 2007. (Revised July 2011.)
  • 05 Jun 2012
  • First Look

First Look: June 5

bond market. Specifically, we show evidence for reaching for yield among insurance companies, the largest institutional holders of corporate bonds. Insurance companies have capital requirements tied to the... View Details
Keywords: Sean Silverthorne
  • Research Summary

Behavioral Hazard and Public Policy

By: Joshua R. Schwartzstein

It is well recognized that people overuse low-value medical care due to moral hazard—because copays are lower than costs. Now Professor Schwartzstein has introduced the concept of “behavioral hazard” to explain the opposite: people underuse high-value care because... View Details

  • June 2005 (Revised August 2011)
  • Case

Narayana Hrudayalaya Heart Hospital: Cardiac Care for the Poor (A)

By: Tarun Khanna, V. Kasturi Rangan and Merlina Manocaran
Describes the mission, vision, and strategy of a team of entrepreneurs headed by a charismatic heart surgeon who founded a heart hospital in Bangalore, India. The purpose of the hospital was to offer health care for the masses. This tertiary care hospital performed... View Details
Keywords: Social Entrepreneurship; Health Care and Treatment; Goals and Objectives; Social Marketing; Mission and Purpose; Strategic Planning; Social Enterprise; Welfare; Health Industry; Health Industry; Bangalore
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Khanna, Tarun, V. Kasturi Rangan, and Merlina Manocaran. "Narayana Hrudayalaya Heart Hospital: Cardiac Care for the Poor (A)." Harvard Business School Case 505-078, June 2005. (Revised August 2011.)
  • April 2020
  • Supplement

Luvo (B)

By: José B. Alvarez and Natalie Kindred
This case, a follow on to HBS No. 517-049 "Luvo," provides a brief look at changes that have occurred at Luvo, now called Performance Kitchen, since the timing of the first case (mid-2016). Set in January 2020, “Luvo (B)” touches on developments such as the company's... View Details
Keywords: Consumer Behavior; Health; Health Care and Treatment; Nutrition; Food; Strategy; Product Positioning; Product Marketing; Food and Beverage Industry; Agriculture and Agribusiness Industry; Consumer Products Industry; Retail Industry; United States; Canada
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Alvarez, José B., and Natalie Kindred. "Luvo (B)." Harvard Business School Supplement 520-101, April 2020.
  • March 2010 (Revised April 2014)
  • Case

American Well: The Doctor Will E-See You Now

By: Elie Ofek and Ron Laufer
What is next for healthcare IT provider American Well, whose innovative Online Care technology allows physicians to deliver care to patients online in real time? Using American Well's platform, patients with non-emergency health concerns can communicate with physicians... View Details
Keywords: Entrepreneurship; Health Care and Treatment; Technological Innovation; Growth and Development Strategy; Market Entry and Exit; Service Delivery; Online Technology; Health Industry
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Ofek, Elie, and Ron Laufer. "American Well: The Doctor Will E-See You Now." Harvard Business School Case 510-061, March 2010. (Revised April 2014.)
  • September 2023
  • Case

Healthy.io: The Negotiation for the Medical Selfie

By: Amit Goldenberg and Kumba Sennaar
Healthy.io, an Israeli digital health company, prepares to enter the U.S. market with its chronic kidney disease test. A product safety approval is delayed, putting the company’s cash runway at risk. How should the CEO negotiate his offer to insurance companies ahead... View Details
Keywords: Negotiation; Entrepreneurship; Venture Capital; Operations; Business Startups; Market Entry and Exit; Health Industry; Israel; United Kingdom; United States
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Goldenberg, Amit, and Kumba Sennaar. "Healthy.io: The Negotiation for the Medical Selfie." Harvard Business School Case 924-001, September 2023.
  • April 2008 (Revised May 2008)
  • Case

Commonwealth Care Alliance: Elderly and Disabled Care

By: Michael E. Porter and Jennifer F Baron
Individuals enrolled in both Medicare and Medicaid, known as dual eligibles, are among the highest-cost beneficiaries in the US. Commonwealth Care Alliance, a small nonprofit insurer and care delivery system in Massachusetts, operated under a public demonstration... View Details
Keywords: Programs; Public Sector; Alliances; Policy; Age; Service Delivery; Value; Health Care and Treatment; Welfare; Insurance Industry; Insurance Industry; Massachusetts
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Porter, Michael E., and Jennifer F Baron. "Commonwealth Care Alliance: Elderly and Disabled Care." Harvard Business School Case 708-502, April 2008. (Revised May 2008.)
  • September 2009
  • Case

The Risk Management Foundation of the Harvard Medical Institutions, Inc.

By: Richard M.J. Bohmer, Stephen P. Bradley and Natalie Kindred
Through its uniquely proactive approach to medical malpractice risk management, the Risk Management Foundation (RMF) has decreased claims—and premiums—for the Harvard hospitals it insures. The RMF is the captive medico-legal insurer of the Harvard medical institutions... View Details
Keywords: Cost Management; Insurance; Health Care and Treatment; Risk Management; Performance Improvement; Safety; Health Industry; Health Industry; Boston
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Bohmer, Richard M.J., Stephen P. Bradley, and Natalie Kindred. "The Risk Management Foundation of the Harvard Medical Institutions, Inc." Harvard Business School Case 610-014, September 2009.
  • Article

Motivated Inferences of Price and Quality in Healthcare Decisions

By: Emily Prinsloo, Kate Barasz and Peter A. Ubel
Policy makers have increasingly advocated for healthcare price transparency, whereby prices are made salient before services are rendered. While such policies may empower consumers, they also bring price to the forefront of healthcare choices as never before, with yet... View Details
Keywords: Healthcare; Price Transparency; Health Care and Treatment; Price; Quality; Perception; Consumer Behavior; Decisions; Insurance
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Prinsloo, Emily, Kate Barasz, and Peter A. Ubel. "Motivated Inferences of Price and Quality in Healthcare Decisions." Special Issue on Healthcare and Medical Decision Making edited by Dipankar Chakravarti, Jian Ni, Meng Zhu. Journal of the Association for Consumer Research 7, no. 2 (April 2022): 186–197.
  • Article

Undermining Value-Based Purchasing — Lessons from the Pharmaceutical Industry

By: Leemore S. Dafny, Christopher Ody and Matt Schmitt
The analogy between value-based purchasing in pharmaceuticals and the new frontier of alternative payment models for health care providers is relatively straightforward. Insurers are increasingly demanding steep discounts from providers in exchange for inclusion in... View Details
Keywords: Drug Copayment Coupons; Prescription Drug Policy; Health Care and Treatment; Insurance; Cost; Policy; Pharmaceutical Industry
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Dafny, Leemore S., Christopher Ody, and Matt Schmitt. "Undermining Value-Based Purchasing — Lessons from the Pharmaceutical Industry." New England Journal of Medicine 375, no. 21 (November 24, 2016): 2013–2015.
  • February 2022 (Revised February 2024)
  • Case

Sekisui House and the In-Home Early Detection Platform

By: John D. Macomber and Akiko Kanno
To address an aging population and sales declines, a major Japanese homebuilder considers pivoting to provide and support an in-home health detection platform, in competition with tech companies. This case considers the point of view of major builders regarding how... View Details
Keywords: Voice Assistants; Architecture; Smart Home; Aging Society; Digitalization; Real Estate; Home Automation; Sensors; Strategy; Digital Platforms; Health Care and Treatment; Housing; Age; Health Industry; Health Industry; Health Industry; Japan
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Macomber, John D., and Akiko Kanno. "Sekisui House and the In-Home Early Detection Platform." Harvard Business School Case 222-070, February 2022. (Revised February 2024.)
  • Teaching Interest

Overview

GHHP-50: The Quality of Health Care in America (undergraduate level)
2016: Head Teaching Fellow
2015: Teaching Fellow 2015 & 2016: Recipient of Harvard University Derek C. Bok Center for Teaching and Learning Certificate of Distinction and Excellence View Details
  • November 2011 (Revised May 2013)
  • Case

The Freelancers Union (A)

By: Michel Anteby and Erin McFee
Sara Horowitz faces a major strategic decision. Founder and CEO of the Freelancers Union, Horowitz has worked tirelessly to operationalize her new mutualist ideals, which comprise collective strength, independence, and shared protections. In 2008, she plans to move the... View Details
Keywords: Labor Unions
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Anteby, Michel, and Erin McFee. "The Freelancers Union (A)." Harvard Business School Case 412-056, November 2011. (Revised May 2013.)
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